Investigating conservation of the albaflavenone biosynthetic pathway and CYP170 bifunctionality in streptomycetes

FEBS Journal

Volumn 279, Issue 9, 2012, Pages 1640-1649

  Moody, Suzy C ^a   Zhao, Bin ^b   Lei, Li ^b   Nelson, David R ^c   Mullins, Jonathan G L ^a   Waterman, Michael R ^b   Kelly, Steven L ^a   Lamb, David C ^a  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

albaflavenone; cytochrome P450; enzyme bifunctionality; evolution; Streptomyces

Indexed keywords

ALBAFLAVENONE; CYTOCHROME P450; CYTOCHROME P450 170A1; CYTOCHROME P450 170B1; FARNESENE; FARNESYL DIPHOSPHATE; SESQUITERPENE; TERPENOID; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BIOSYNTHESIS; CATALYSIS; CHEMICAL MODIFICATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; STREPTOMYCES; STREPTOMYCES ALBUS; STREPTOMYCES COELICOLOR;

ALKYL AND ARYL TRANSFERASES; AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CYTOCHROME P-450 ENZYME SYSTEM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POLYISOPRENYL PHOSPHATES; SESQUITERPENES; STREPTOMYCES; STREPTOMYCES COELICOLOR;

STREPTOMYCES; STREPTOMYCES ALBUS; STREPTOMYCES COELICOLOR; STREPTOMYCINEAE;

EID: 84860222640     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08447.x     Document Type: Article

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