Genotoxicity evaluation in workers occupationally exposed to lead

International Journal of Hygiene and Environmental Health

Volumn 213, Issue 2, 2010, Pages 99-106

  Grover, Paramjit ^a   Rekhadevi, P V ^a   Danadevi, K ^a   Vuyyuri, S B ^a   Mahboob, M ^a   Rahman, M F ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Chromosomal aberrations; Comet assay; Genotoxicity; Lead; Micronucleus test

Indexed keywords

AMINOLEVULINIC ACID; ANTIOXIDANT; LEAD; PORPHOBILINOGEN SYNTHASE;

ADULT; ARTICLE; BLOOD; CASE CONTROL STUDY; CHEMICALLY INDUCED DISORDER; CHROMOSOME ABERRATION; COMET ASSAY; DNA DAMAGE; ENZYMOLOGY; ERYTHROCYTE; HUMAN; MALE; METABOLISM; MICRONUCLEUS TEST; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; URINE;

ADULT; AMINOLEVULINIC ACID; ANTIOXIDANTS; CASE-CONTROL STUDIES; CHROMOSOME ABERRATIONS; COMET ASSAY; DNA DAMAGE; ERYTHROCYTES; HUMANS; LEAD; MALE; MICRONUCLEUS TESTS; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; PORPHOBILINOGEN SYNTHASE;

EID: 77649236040     PISSN: 14384639     EISSN: 1618131X     Source Type: Journal    
DOI: 10.1016/j.ijheh.2010.01.005     Document Type: Article

References (56)

1. Aebi H. Catalase. In: Bergmeyer H.U. (Ed). Methods of Enzymatic Analysis 2 (1974), Werlag Chemie, Weinheim 673-678
2. Albertini R.J., Anderson D., Douglas G.R., et al. IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans. Mutat. Res. 463 (2000) 111-172
3. ARC, 1994. Seventh Annual Report on Carcinogens. National Toxicology Program. National Institute of Environmental Health Sciences, Research Triangle Park, NC.
4. Astrin K.H., Bishop D.F., Wetmur J.G., Kaul B., Davidow B., and Desnick R.J. delta-Aminolevulinic acid dehydratase isozymes and lead toxicity. Ann. N. Y. Acad. Sci. 514 (1987) 23-29
5. ATSDR. 2000. Lead toxicity. Atlanta, GA: Agency for Toxic Substances and Disease Registry. Available: http://www.atsdr.cdc.gov/HEC/CSEM/lead/index.html.
6. Berlin A., and Schaller K.H. European standardized method for the determination of delta aminolevulinic acid dehydratase activity in blood. Z. Klin. Chem. Klin. Biochem. 128 (1974) 389-390
7. Bonassi S., Abbondandolo A., Camurri L., Dal Pra A., De Ferrari M., Degrassi F., Forni A., Lamberti L., Lando C., Padovani P., et al. Are chromosome aberrations in circulating lymphocytes predictive of future cancer onset in humans? Preliminary results of an Italian cohort study. Cancer Genet. Cytogenet. 79 (1995) 133-135
8. Bonassi S., Neri M., Lando C., Ceppi M., Lin Y.P., Chang W.P., Holland N., Kirsch-Volders M., Zeiger E., Fenech M., and HUMN Collaborative Group. Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the Human Micro Nucleus project. Mutat. Res. 543 (2003) 155-166
9. Chia S.E., Zhou H.J., Yap E., Tham M.T., Dong N.V., Hong T., N.T., and Chia K.S. Association of renal function and δ-aminolevulinic acid dehydratase polymorphism among Vietnamese and Singapore workers exposed to inorganic lead. Occup. Environ. Med. 63 (2006) 180-186
10. Collins A.R. Comet assay for DNA damage and repair: principles, applications and limitations. Mol. Biotechnol. 26 (2004) 249-261
11. Danadevi K., Rozati R., Banu B.S., Rao P.H., and Grover P. DNA damage in workers exposed to lead using comet assay. Toxicology 187 (2003) 183-193
12. Devi K.D., Banu B.S., Grover P., and Jamil K. Genotoxic effect of lead nitrate on mice using SCGE (comet assay). Toxicology 145 (2000) 195-201
13. Duydu Y., and Suzen H.S. Influence of δ-aminolevulinic acid dehydratase (ALAD) polymorphism on the frequency of sister chromatid exchange (SCE) and the number of high-frequency cells (HFCs) in lymphocytes from led-exposed workers. Mutat. Res. 540 (2003) 79-88
14. Duydu Y., Suzen H.S., Aydin A., Cander O., Uysal H., Isimer A., and Vural N. Correlation between lead exposure indicators and sister chromatid exchange (SCE) frequencies in lymphocytes from inorganic lead exposed workers. Arch. Environ. Contam. Toxicol. 41 (2001) 241-246
15. Fenech M., and Morley A.A. Measurement of micronuclei in lymphocytes. Mutat. Res. 147 (1985) 29-36
16. Fracasso M.A., Perbellini L., Solda S., Talamini G., and Franceschetti P. Lead induced DNA strand breaks in lymphocytes of exposed workers: role of reactive oxygen species and protein kinase C. Mutat. Res. 515 (2002) 159-169
17. Gurer-Orhan H., Sabir H.U., and Ozgunes H. Correlation between clinical indicators of lead poisoning and oxidative stress parameters in controls and lead exposed workers. Toxicology 195 (2004) 147-154
18. Hamurcu Z., Donmezm H., Saraymen R., and Demirtas H. Micronucleus frequencies in workers exposed to lead, zinc, and cadmium. Biol. Trace Elem. Res. 83 (2001) 97-102
19. Hiraku Y., and Kawanishi S. Mechanism of oxidative DNA damage induced by aminolevulinic acid in the presence of copper ion. Cancer Res. 56 (1996) 1786-1793
20. Hulka B.S., Wilcosky T.C., and Griffith J.D. Biological Markers in Epidemiology (1990), Oxford University Press, New York
21. Jagetia G.C., and Aruna R. Effect of various concentrations of lead nitrate on the induction of micronuclei in mouse bone marrow. Mutat. Res. 415 (1998) 131-137
22. Kapka L., Baumgartner A., Siwinska E., Knudsen L.E., Anderson D., and Mielzynska D. Enviornmental lead exposure increases micronuclei in children. Mutagenesis 22 (2007) 201-207
23. Kassie F., Parzefall W., and Knasmuller S. Single cell gel electrophoresis assay: a new technique for human biomonitoring studies. Mutat. Res. 463 (2000) 13-31
24. Lazutka J.R., Lekevicius R., Dedonyte V., Maciuleviciute-Gervers L., Mierauskiene J., Rudaitiene S., and Slapsyte G. Chromosomal aberrations and sister chromatid exchanges in Lithuanian populations: effects of occupational and environmental exposures. Mutat. Res. 445 (1999) 225-239
25. Lutz T.M., Nirel P.M.V., and Schmidt B. Whole blood analysis by ICP-MS. In: Holland G., and Eaton A.N. (Eds). Applications of Plasma Source Mass Spectrometry (1991), The Royal Society of Chemistry, Cambridge, UK 96-100
26. Minozzo R., Deimling L.I., Gigante L.P., and Santos-Mello R. Micronuclei in peripheral blood lymphocytes of workers exposed to lead. Mut. Res. 565 (2004) 53-60
27. Norppa H., and Falck G.C.M. What do human micronuclei contain?. Mutagenesis 18 (2003) 221-233.
28. Paglia D.E., and Valentine W. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 70 (1967) 158-169
29. Palus J., Rudzynski K., Dziubaltowska E., Wyszynska K., Natarajan A.T., and Nilsson R. Genotoxic effects of occupational exposure to lead and cadmium. Mutat. Res. 540 (2003) 19-28
30. Pinto D., Ceballos J.M., Garcia G., Guzman P., Del Razo L.M., Vera E., Gomez H., Garcia A., and Gonsebatt M.E. Increased cytogenetic damage in outdoor painters. Mutat. Res. 467 (2000) 105-111
31. Rajaraman P., Stewart P.A., Samet J.M., et al. Lead, genetic susceptibility, and risk of adult brain tumors. Cancer Epidemiol. Biomarkers Prev. 15 (2006) 2514-2520
32. Rekhadevi P.V., Mahboob M., Rahman M.F., and Grover P. Genetic damage in wood dust-exposed workers. Mutagenesis 24 (2009) 59-65
33. Richardson A. Analysis of cytogenetic abnormalities. Part I: Chromosome analysis. I. In: Barch M.J. (Ed). The ACT Cytogenetic Manual (1991), Raven Press, New York 329-382
34. Sakai T., and Morita Y. Delta-aminolevulinic acid in plasma or whole blood as a sensitive indicator of lead effects, and its relation to other heme-related parameters. Int. Arch. Occup. Environ. Health 68 (1996) 126-132
35. Shaik A.P., and Jamil K. Individual susceptibility and genotoxicity in workers exposed to hazardous materials like lead. J Hazard Mater. 168 (2009) 918-924
36. Shaik A.P., Sankar S., Satish Reddy C., Prabhavathy Das G., and Jamil K. Lead induced genotoxicity in lymphocytes from peripheral blood samples of humans: in vitro study. Drug Chem. Toxicol. 29 (2006) 111-124
37. Singh N.P., McCoy M.T., Tice R.R., and Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175 (1988) 184-191
38. Sithisarankul P., Schwartz B.S., Lee B.K., Kelsey K.T., and Strickland P.T. Aminolevulinic acid dehydratase genotype mediates plasma levels of the neurotoxin, 5-aminolevulinic acid, in lead-exposed workers. Am. J. Ind. Med. 32 (1997) 15-20
39. Steenland K., and Boffeta P. Lead and cancer in humans: where are we now?. Am. J. Ind. Med. 38 (2000) 295-299
40. Steinmetz-Beck A., Szahidewicz-Krupska E., Beck B., Poreba R., and Andrzejak R. Genotoxicity effect of chronic lead exposure assessed using the comet assay. Med. Pr. 56 (2005) 295-302
41. Sun Y., Oberley L.W., and Li Y. A simple method for clinical assay of superoxide dismutase. Clin. Chem. 34 (1988) 497-500
42. Süzen H.S., Duydu Y., Aydin A., Işimer A., and Vural N. Influence of the delta-aminolevulinic acid dehydratase (ALAD) polymorphism on biomarkers of lead exposure in Turkish storage battery manufacturing workers. Am. J. Ind. Med. 43 (2003) 165-171
43. Tolbert P.E., Shy C.M., and Allen. J.W. Micronuclei and other nuclear anomalies in buccal smear: method development. Mutat. Res. 271 (1992) 69-77
44. Tomokuni K., and Ogata M. Simple method for determination of urinary delta aminolevulinic acid as an index of lead exposure. Clin. Chem. 18 (1972) 1534-1536
45. Tsaih S., Schwartz J., Ting Lee M., Amarasiriwardena C., Aro A., Sparrow D., and Hu H. The independent contribution of bone and erythrocyte lead to urinary lead among middle aged and elderly men: the normative aging study. Environ. Health Perspect. 107 (1999) 391-396
46. Vaglenov A., Carbonell E., and Marcos R. Biomonitoring of workers exposed to lead, genotoxic effects, its modulation by polyvitamin treatment and evaluation of the induced radioresistance. Mutat. Res. 418 (1998) 79-92
47. Vaglenov A., Creus A., Laltchev S., Petkova V., Pavlova S., and Marcos R. Occupational exposure to lead and induction of genetic damage. Environ. Health Perspect. 109 (2001) 295-298
48. Vaglenov A.K., Laltchev S.G., Nosko M.S., Pavlova S.P., Petkova V.V., and Karadjov A.D. Cytogenetic monitoring of exposed workers to lead. Cent. Eur. J. Occup. Environ. Med. 3 (1997) 298-308
49. Valverde M., Fortoul T.I., Díaz-Barriga F., Mejía J., and del Castillo E.R. Genotoxicity induced in CD-1 mice by inhaled lead: differential organ response. Mutagenesis 17 (2002) 55-61
50. Verma Y., Gautam K., and Rana S.V.S. Biological monitoring of exposure to inorganic lead with special reference to women- a case study of Indian bangle makers. Toxicol. Int. 14 (2007) 123-131
51. Wasowicz W., Nève J., and Peretz A. Optimized steps in fluorometric determination of thiobarbituric acid-reactive substances in serum: importance of extraction pH and influence of sample preservation and storage. Clin. Chem. 39 (1993) 2522-2526
52. WHO. 1995. Human Exposure to Lead. WHO, Geneva.
53. Wozniak K., and Blasiak J. In vitro gentotoxicity of lead acetate: induction of single and double strand breaks and DNA-protein cross links. Mutat. Res. 535 (2003) 127-139
54. Wu F.M., Chang P., Wu C., and Kuo H. Correlations of blood lead with DNA protein cross-links and sister chromatid exchanges in lead workers. Cancer Epidemiol. Biomarkers Prev. 11 (2002) 287-290
55. Yanez L., Garcia-Nieto E., Rojas E., Carrizales L., Mejia J., Calderon J., Razo I., and Diaz-Barriga F. DNA damage in blood cells from children exposed to arsenic and lead in a mining area. Environ. Res. 93 (2003) 231-240
56. Zhijian C., Jialin L., Shijie C., Wei Z., Wei W., Lifen J., Hongping D., and Jiliang H. Evaluating the genotoxic effects of workers exposed to lead using micronucleus assay, comet assay and TCR gene mutation test. Toxicology 223 (2006) 219-226