Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 17, 2012, Pages

  Horiuchi, Dai ^a   Huskey, Noelle E ^a   Kusdra, Leonard ^a   Wohlbold, Lara ^b   Merrick, Karl A ^b   Zhang, Chao ^a,c   Creasman, Katelyn J ^a   Shokat, Kevan M ^a,c   Fisher, Robert P ^b   Goga, Andrei ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Analog sensitive kinase; Cyclin dependent kinase

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIN DEPENDENT KINASE 2; SMALL INTERFERING RNA;

ARTICLE; CANCER GROWTH; CELL ANCHORAGE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL TRANSFORMATION; CHEMICAL ANALYSIS; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; ONCOGENE; PRIORITY JOURNAL; PROTEIN FUNCTION; SENSITIVITY ANALYSIS;

ANIMALS; CELL ADHESION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE 2; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; ONCOGENES; RNA, SMALL INTERFERING;

EID: 84860138369     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1111317109     Document Type: Article

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