Comparative analysis of the heptahelical transmembrane bundles of G protein-coupled receptors

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Okada, Tetsuji ^a  

^a GAKUSHUIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

11 CIS RETINAL; G PROTEIN COUPLED RECEPTOR; RHODOPSIN; LIGAND; RETINAL;

ARTICLE; COW; CRYSTAL STRUCTURE; HEPTAHELICAL TRANSMEMBRANE BUNDLE; LIGAND BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SQUID; STRUCTURE ANALYSIS; ANIMAL; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION;

ANIMALS; CATTLE; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, G-PROTEIN-COUPLED; RETINALDEHYDE; RHODOPSIN;

EID: 84860122218     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035802     Document Type: Article

References (33)

1. Lefkowitz RJ, (2007) Seven transmembrane receptors: something old, something new. Acta Physiol 190: 9-19.
2. Krishnan A, Almén MS, Fredriksson R, Schiöth HB, (2012) The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi. PLoS One 7: e29817.
3. Haga K, Kruse AC, Asada H, Yurugi-Kobayashi T, Shiroishi M, et al. (2012) Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist. Nature 482: 547-551.
4. Kruse AC, Hu J, Pan AC, Arlow DH, Rosenbaum DM, et al. (2012) Structure and dynamics of the M3 muscarinic acetylcholine receptor. Nature 482: 552-556.
5. Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, et al. (2012) Crystal structure of a lipid G protein-coupled receptor. Science 335: 851-855.
6. Congreve M, Langmead CJ, Mason JS, Marshall FH, (2011) Progress in structure based drug design for G protein-coupled receptors. J Med Chem 54: 4283-4311.
7. Katritch V, Cherezov V, Stevens RC, (2012) Diversity and modularity of G protein-coupled receptor structures. Trends Pharmacol Sci 33: 17-27.
8. Xu F, Wu H, Katritch V, Han GW, Jacobson KA, et al. (2011) Structure of an agonist-bound human A2A adenosine receptor. Science 332: 322-327.
9. Warne T, Moukhametzianov R, Baker JG, Nehmé R, Edwards PC, et al. (2011) The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor. Nature 469: 241-244.
10. Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, et al. (2000) Crystal structure of rhodopsin: a G protein-coupled receptor. Science 289: 739-745.
11. Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, et al. (2007) High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science 318: 1258-1265.
12. Krissinel E, Henrick K, (2004) Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. Acta Crystallogr D60: 2256-2268.
13. Emsley P, Lohkamp B, Scott WG, Cowtan K, (2010) Features and development of Coot. Acta Crystallogr D66: 486-501.
14. Winn MD, Ballard CC, Cowtan KD, Dodson EJ, Emsley P, et al. (2011) Overview of the CCP4 suite and current developments. Acta Crystallogr D67: 235-242.
15. Ballesteros JA, Weinstein H, (1995) Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors. Methods Neurosci 25: 366-428.
16. Warne T, Serrano-Vega MJ, Baker JG, Moukhametzianov R, Edwards PC, et al. (2008) Structure of a β1-adrenergic G-protein-coupled receptor. Nature 454: 486-491.
17. Moukhametzianov R, Warne T, Edwards PC, Serrano-Vega MJ, Leslie AG, et al. (2011) Two distinct conformations of helix 6 observed in antagonist-bound structures of a β1-adrenergic receptor. Proc Natl Acad Sci USA 108: 8228-8232.
18. Okada T, Palczewski K, (2001) Crystal structure of rhodopsin: implications for vision and beyond. Curr Opin Struct Biol 11: 420-426.
19. Schertler GF, Villa C, Henderson R, (1993) Projection structure of rhodopsin. Nature 362: 770-772.
20. Kabsch W, Sander C, (1983) Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers 22: 2577-2637.
21. Robinson PR, Cohen GB, Zhukovsky EA, Oprian DD, (1992) Constitutively active mutants of rhodopsin. Neuron 9: 719-725.
22. Nakamichi H, Okada T, (2006) Crystallographic analysis of primary visual photochemistry. Angew Chem Int Ed 45: 4270-4273.
23. Nakamichi H, Okada T, (2006) Proc Natl Acad Sci USA 103: 12729-12734.
24. Farrens DL, Altenbach C, Yang K, Hubbell WL, Khorana HG, (1996) Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science 274: 768-770.
25. Park JH, Scheerer P, Hofmann KP, Choe HW, Ernst OP, (2008) Crystal structure of the ligand-free G-protein-coupled receptor opsin. Nature 454: 183-187.
26. Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, et al. (2011) Crystal structure of the β2 adrenergic receptor-Gs protein complex. Nature 477: 549-555.
27. Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, et al. (2011) Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature 469: 175-180.
28. Han M, Smith SO, Sakmar TP, (1998) Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6. Biochemistry 37: 8253-8261.
29. Lu ZL, Hulme EC, (1999) The functional topography of transmembrane domain 3 of the M1 muscarinic acetylcholine receptor, revealed by scanning mutagenesis. J Biol Chem 274: 7309-7315.
30. Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie G, et al. (2011) The structural basis of agonist-induced activation in constitutively active rhodopsin. Nature 471: 656-660.
31. Okada T, Fujiyoshi Y, Silow M, Navarro J, Landau EM, et al. (2002) Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography. Proc Natl Acad Sci USA 99: 5982-5987.
32. Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, et al. (2004) UCSF Chimera-a visualization system for exploratory research and analysis. J Comput Chem 25: 1605-1612.
33. McNicholas S, Potterton E, Wilson KS, Noble MEM, (2011) Presenting your structures: the CCP4mg molecular-graphics software. Acta Cryst D67: 386-394.