메뉴 건너뛰기




Volumn 7, Issue 4, 2012, Pages

Mechanical strain regulates osteoblast proliferation through integrin-mediated ERK activation

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; BETA5 INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BETA INTEGRIN; FLAVONOID; SMALL INTERFERING RNA;

EID: 84859967041     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035709     Document Type: Article
Times cited : (112)

References (61)
  • 1
    • 0028903329 scopus 로고
    • Inhibition of bone resorption and stimulation of formulation by mechanical loading of the modeling rat ulna in vivo
    • Hillam RA, Skerry TM, (1995) Inhibition of bone resorption and stimulation of formulation by mechanical loading of the modeling rat ulna in vivo. J Bone Miner Res 10: 683-689.
    • (1995) J Bone Miner Res , vol.10 , pp. 683-689
    • Hillam, R.A.1    Skerry, T.M.2
  • 2
    • 13444276396 scopus 로고    scopus 로고
    • Signal transduction and mechanical stress
    • Hughes-Fulford M, (2004) Signal transduction and mechanical stress. Sci STKE 249: RE12.
    • (2004) Sci STKE , vol.249
    • Hughes-Fulford, M.1
  • 3
  • 5
    • 0026488291 scopus 로고
    • Perspectives: bone's mechanical usage windows, Bone and Mineral
    • Frost HM, (1992) Perspectives: bone's mechanical usage windows, Bone and Mineral 19: 257-271.
    • (1992) , vol.19 , pp. 257-271
    • Frost, H.M.1
  • 6
    • 0029985585 scopus 로고    scopus 로고
    • In vivo measurement of human tibial strains during vigorous activity
    • Burr DB, Milgrom C, Fyhrie D, Fowood M, Nyska M, et al. (1996) In vivo measurement of human tibial strains during vigorous activity. Bone 18: 405-410.
    • (1996) Bone , vol.18 , pp. 405-410
    • Burr, D.B.1    Milgrom, C.2    Fyhrie, D.3    Fowood, M.4    Nyska, M.5
  • 7
    • 0142221955 scopus 로고    scopus 로고
    • Mechanobiology of cartilage: how do internal and external stresses affect mechanochemical transduction and elastic energy storage?
    • Silver FH, Bradica G, (2002) Mechanobiology of cartilage: how do internal and external stresses affect mechanochemical transduction and elastic energy storage? Biomech Model Mechanobiol 1: 219-238.
    • (2002) Biomech Model Mechanobiol , vol.1 , pp. 219-238
    • Silver, F.H.1    Bradica, G.2
  • 8
  • 9
    • 22044439283 scopus 로고    scopus 로고
    • Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells
    • Batra NN, Li YJ, Yellowley CE, You L, Malone AM, et al. (2005) Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells. J Biomech 38: 1909-1917.
    • (2005) J Biomech , vol.38 , pp. 1909-1917
    • Batra, N.N.1    Li, Y.J.2    Yellowley, C.E.3    You, L.4    Malone, A.M.5
  • 10
    • 33646417935 scopus 로고    scopus 로고
    • Comparison of biophysical stimuli for mechano-regulation of tissue differentiation during fracture healing
    • Isaksson H, Wilson W, Donkelaar CC, Huiskes R, Ito K, (2006) Comparison of biophysical stimuli for mechano-regulation of tissue differentiation during fracture healing. J Biomech 39: 1507-1516.
    • (2006) J Biomech , vol.39 , pp. 1507-1516
    • Isaksson, H.1    Wilson, W.2    Donkelaar, C.C.3    Huiskes, R.4    Ito, K.5
  • 12
    • 33645773666 scopus 로고    scopus 로고
    • Local force and geometry sensing regulate cell functions
    • Viola V, Michael S, (2006) Local force and geometry sensing regulate cell functions. Molecular cell biology 7: 265-275.
    • (2006) Molecular Cell Biology , vol.7 , pp. 265-275
    • Viola, V.1    Michael, S.2
  • 13
    • 33748166972 scopus 로고    scopus 로고
    • Biomechanical and molecular regulation of bone remodeling
    • Robling AG, Castillo AB, Turner CH, (2006) Biomechanical and molecular regulation of bone remodeling. Annu Rev Biomed Eng 8: 455-498.
    • (2006) Annu Rev Biomed Eng , vol.8 , pp. 455-498
    • Robling, A.G.1    Castillo, A.B.2    Turner, C.H.3
  • 14
    • 0036712047 scopus 로고    scopus 로고
    • Mechanical strain and bone cell function: A review
    • Ehrlich PJ, Lanyon LE, (2002) Mechanical strain and bone cell function: A review. Osteoporosis Int 13: 688-700.
    • (2002) Osteoporosis Int , vol.13 , pp. 688-700
    • Ehrlich, P.J.1    Lanyon, L.E.2
  • 15
    • 24744462930 scopus 로고    scopus 로고
    • BMP-2 and insulin-like growth factor-I mediate Osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways
    • Celil AB, Campbell PG, (2005) BMP-2 and insulin-like growth factor-I mediate Osterix (Osx) expression in human mesenchymal stem cells via the MAPK and protein kinase D signaling pathways. J Biol Chem 280: 31353-31359.
    • (2005) J Biol Chem , vol.280 , pp. 31353-31359
    • Celil, A.B.1    Campbell, P.G.2
  • 16
    • 17744381762 scopus 로고    scopus 로고
    • Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation
    • Zhao G, Monier-Faugere MC, Langub MC, Geng Z, Nakayama T, et al. (2000) Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation. Endocrinology 141: 2674-2682.
    • (2000) Endocrinology , vol.141 , pp. 2674-2682
    • Zhao, G.1    Monier-Faugere, M.C.2    Langub, M.C.3    Geng, Z.4    Nakayama, T.5
  • 17
    • 0037007077 scopus 로고    scopus 로고
    • Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation. Proc. Natl. Acad. Sci. U. S. A
    • Yoshida K, Oida H, Kobayashi T, Maruyama T, Tanaka M, et al. (2002) Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation. Proc. Natl. Acad. Sci. U. S. A. 99: 4580-4585.
    • (2002) , vol.99 , pp. 4580-4585
    • Yoshida, K.1    Oida, H.2    Kobayashi, T.3    Maruyama, T.4    Tanaka, M.5
  • 18
    • 0037345529 scopus 로고    scopus 로고
    • Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways
    • Kapur S, Baylink DJ, Lau KH, (2003) Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways. Bone 32: 241-251.
    • (2003) Bone , vol.32 , pp. 241-251
    • Kapur, S.1    Baylink, D.J.2    Lau, K.H.3
  • 20
    • 33344455592 scopus 로고    scopus 로고
    • Molecular pathways mediating mechanical signaling in bone
    • Rubin J, Rubin C, Jacobs CR, (2006) Molecular pathways mediating mechanical signaling in bone. Gene 367: 1-16.
    • (2006) Gene , vol.367 , pp. 1-16
    • Rubin, J.1    Rubin, C.2    Jacobs, C.R.3
  • 21
    • 0033848751 scopus 로고    scopus 로고
    • Mechanically strained cell of the osteoblast lineage organize their extracellular matrix through unique sites of avB3-integrin expression
    • Wozniak M, Fausto A, Carron CP, Meyer DM, Hruska KA, (2000) Mechanically strained cell of the osteoblast lineage organize their extracellular matrix through unique sites of avB3-integrin expression. J Bone Miner Res 15: 1731-1745.
    • (2000) J Bone Miner Res , vol.15 , pp. 1731-1745
    • Wozniak, M.1    Fausto, A.2    Carron, C.P.3    Meyer, D.M.4    Hruska, K.A.5
  • 22
    • 85056056449 scopus 로고    scopus 로고
    • Osteogenic predifferentiation of human bone marrow-derived stem cells by short-term mechanical stimulation
    • Matziolis D, Tuischer J, Matziolis G, Kasper G, Duda G, et al. (2011) Osteogenic predifferentiation of human bone marrow-derived stem cells by short-term mechanical stimulation. Open Orthop J 5: 1-6.
    • (2011) Open Orthop J , vol.5 , pp. 1-6
    • Matziolis, D.1    Tuischer, J.2    Matziolis, G.3    Kasper, G.4    Duda, G.5
  • 23
    • 78649794618 scopus 로고    scopus 로고
    • Mechanical integrin stress and magnetic forces induce biological responses in mesenchymal stem cells which depend on environmental factors
    • Kasten A, Muller P, Bulnheim U, Groll J, Bruellhoff K, et al. (2010) Mechanical integrin stress and magnetic forces induce biological responses in mesenchymal stem cells which depend on environmental factors. J Cell Biochem 111: 1586-1597.
    • (2010) J Cell Biochem , vol.111 , pp. 1586-1597
    • Kasten, A.1    Muller, P.2    Bulnheim, U.3    Groll, J.4    Bruellhoff, K.5
  • 24
    • 2942711895 scopus 로고    scopus 로고
    • Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways
    • Sakata T, Wang Y, Halloran BP, Elalieh HZ, Cao J, et al. (2004) Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways. J Bone Miner Res 19: 436-446.
    • (2004) J Bone Miner Res , vol.19 , pp. 436-446
    • Sakata, T.1    Wang, Y.2    Halloran, B.P.3    Elalieh, H.Z.4    Cao, J.5
  • 25
    • 33845987983 scopus 로고    scopus 로고
    • Skeletal unloading induces osteoblast apoptosis and targets alpha5beta1-PI3K-Bcl-2 signaling in rat bone
    • Dufour C, Holy X, Marie PJ, (2007) Skeletal unloading induces osteoblast apoptosis and targets alpha5beta1-PI3K-Bcl-2 signaling in rat bone. Exp Cell Res 313: 394-403.
    • (2007) Exp Cell Res , vol.313 , pp. 394-403
    • Dufour, C.1    Holy, X.2    Marie, P.J.3
  • 26
    • 0032747591 scopus 로고    scopus 로고
    • The response of bone to unloading
    • Bikle DD, Halloran BP, (1999) The response of bone to unloading. J Bone Miner Metab 17 (4): 233-44.
    • (1999) J Bone Miner Metab , vol.17 , Issue.4 , pp. 233-244
    • Bikle, D.D.1    Halloran, B.P.2
  • 27
    • 33646429482 scopus 로고    scopus 로고
    • Bone turnover across the menopause transition: correlations with inhibins and follicle-stimulating hormone
    • Perrien DS, Achenbach SJ, Bledsoe SE, Walser B, Suva LJ, et al. (2006) Bone turnover across the menopause transition: correlations with inhibins and follicle-stimulating hormone. J Clin Endocrinol Metab 91: 1848-1854.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1848-1854
    • Perrien, D.S.1    Achenbach, S.J.2    Bledsoe, S.E.3    Walser, B.4    Suva, L.J.5
  • 28
    • 33745040527 scopus 로고    scopus 로고
    • Bone loss goes beyond estrogen
    • Martin TJ, Gaddy D, (2006) Bone loss goes beyond estrogen. Nat Med 12: 612-613.
    • (2006) Nat Med , vol.12 , pp. 612-613
    • Martin, T.J.1    Gaddy, D.2
  • 29
    • 80052510417 scopus 로고    scopus 로고
    • Simulated evolution of the vertebral body based on basic multicellular unit activities
    • Wang C, Zhang C, Han J, Wu H, Fan Y, (2011) Simulated evolution of the vertebral body based on basic multicellular unit activities. J Bone Miner Metab 29 (4): 466-476.
    • (2011) J Bone Miner Metab , vol.29 , Issue.4 , pp. 466-476
    • Wang, C.1    Zhang, C.2    Han, J.3    Wu, H.4    Fan, Y.5
  • 30
    • 0035992651 scopus 로고    scopus 로고
    • Mechanical strain inhibits RANKL expression through activation of ERK1/2 in bone marrow stromal cells
    • Rubin J, Murphy T, Fan X, Goldschmidt M, Taylor W, (2002) Mechanical strain inhibits RANKL expression through activation of ERK1/2 in bone marrow stromal cells. J Bone Miner Res 17, 1452-1460.
    • (2002) J Bone Miner Res 17, , pp. 1452-1460
    • Rubin, J.1    Murphy, T.2    Fan, X.3    Goldschmidt, M.4    Taylor, W.5
  • 31
    • 0034635477 scopus 로고    scopus 로고
    • MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1
    • Xiao G, Jiang D, Thomas P, Benson MD, Guan K, et al. (2000) MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1. J Biol Chem 275: 4453-4459.
    • (2000) J Biol Chem , vol.275 , pp. 4453-4459
    • Xiao, G.1    Jiang, D.2    Thomas, P.3    Benson, M.D.4    Guan, K.5
  • 32
    • 0037184053 scopus 로고    scopus 로고
    • Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells
    • Sowa H, Kaji H, Yamaguchi T, Sugimoto T, Chihara K, (2002) Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells. J Biol Chem 277: 36024-36031.
    • (2002) J Biol Chem , vol.277 , pp. 36024-36031
    • Sowa, H.1    Kaji, H.2    Yamaguchi, T.3    Sugimoto, T.4    Chihara, K.5
  • 33
    • 0037189499 scopus 로고    scopus 로고
    • The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells
    • Ziros PG, Gil AP, Georgakopoulos T, Habeos I, Kletsas D, et al. (2002) The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells. J Biol Chem 277: 23934-23941.
    • (2002) J Biol Chem , vol.277 , pp. 23934-23941
    • Ziros, P.G.1    Gil, A.P.2    Georgakopoulos, T.3    Habeos, I.4    Kletsas, D.5
  • 34
    • 33748712224 scopus 로고    scopus 로고
    • Modulation of ERK 1/2 and p38 MAPK signaling pathways by ATP in osteoblasts: Involvement of mechanical stress-activated calcium influx, PKC and Src activation
    • Katz S, Boland R, Santillan G, (2006) Modulation of ERK 1/2 and p38 MAPK signaling pathways by ATP in osteoblasts: Involvement of mechanical stress-activated calcium influx, PKC and Src activation. Int J Biochem Cell Biol 38: 2082-2091.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 2082-2091
    • Katz, S.1    Boland, R.2    Santillan, G.3
  • 36
    • 70449526309 scopus 로고    scopus 로고
    • Passage-affected competitive regulation of osteoprotegerin synthesis and the receptor activator of nuclear factor-kappaB ligand mRNA expression in normal human osteoblasts stimulated by the application of cyclic tensile strain
    • Kusumi A, Kusumi T, Miura J, Tateishi T, (2009) Passage-affected competitive regulation of osteoprotegerin synthesis and the receptor activator of nuclear factor-kappaB ligand mRNA expression in normal human osteoblasts stimulated by the application of cyclic tensile strain. J Bone Miner Metab 27: 653-662.
    • (2009) J Bone Miner Metab , vol.27 , pp. 653-662
    • Kusumi, A.1    Kusumi, T.2    Miura, J.3    Tateishi, T.4
  • 37
    • 0037214222 scopus 로고    scopus 로고
    • A short pulse of mechanical force induces gene expression and growth in MC3T3-E1 osteoblasts via an ERK 1/2 pathway
    • Hatton JP, Pooran M, Li CF, Luzzio C, Hughes Fulford M, (2003) A short pulse of mechanical force induces gene expression and growth in MC3T3-E1 osteoblasts via an ERK 1/2 pathway. J Bone Miner Res 18: 58-66.
    • (2003) J Bone Miner Res , vol.18 , pp. 58-66
    • Hatton, J.P.1    Pooran, M.2    Li, C.F.3    Luzzio, C.4    Hughes Fulford, M.5
  • 38
    • 34547906444 scopus 로고    scopus 로고
    • Mechanical Stress-Mediated Runx2 Activation is Dependent on Ras/ERK1/2 MAPK Signaling in Osteoblasts
    • Takahiro K, Tetsu T, Toshiyuki T, Wataru A, Tatsuji N, (2007) Mechanical Stress-Mediated Runx2 Activation is Dependent on Ras/ERK1/2 MAPK Signaling in Osteoblasts. Journal of Cellular Biochemistry 101: 1266-1277.
    • (2007) Journal of Cellular Biochemistry , vol.101 , pp. 1266-1277
    • Takahiro, K.1    Tetsu, T.2    Toshiyuki, T.3    Wataru, A.4    Tatsuji, N.5
  • 39
    • 33645670096 scopus 로고    scopus 로고
    • Response to mechanical strain in an immortalized pre-osteoblast cell is dependent on ERK1/2
    • Fan X, Rahnert JA, Murphy TC, NanesMS, Greenfield EM, Rubin J, (2006) Response to mechanical strain in an immortalized pre-osteoblast cell is dependent on ERK1/2. J Cell Physiol 207: 454-460.
    • (2006) J Cell Physiol , vol.207 , pp. 454-460
    • Fan, X.1    Rahnert, J.A.2    Murphy, T.C.3    Nanes, M.S.4    Greenfield, E.M.5    Rubin, J.6
  • 41
    • 0037383404 scopus 로고    scopus 로고
    • Tensegrity I, Cell structure and hierarchical systems biology
    • Ingber DE, (2003) Tensegrity I, Cell structure and hierarchical systems biology. J Cell Sci 116: 1157-1173.
    • (2003) J Cell Sci , vol.116 , pp. 1157-1173
    • Ingber, D.E.1
  • 42
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: the road taken
    • Edwin AC, Joan SB, (1995) Integrins and signal transduction pathways: the road taken. Science 268: 233-239.
    • (1995) Science , vol.268 , pp. 233-239
    • Edwin, A.C.1    Joan, S.B.2
  • 43
  • 44
    • 29444433258 scopus 로고    scopus 로고
    • Mechanical stretch-induced hypertrophy of neonatal rat ventricular myocytes is mediated by β1-integrin- microtubule signaling pathways
    • Yutao X, Geru W, Xiaojun B, Tao G, Aiqun M, (2006) Mechanical stretch-induced hypertrophy of neonatal rat ventricular myocytes is mediated by β1-integrin- microtubule signaling pathways. Eur J Heart Fail 8: 16-22.
    • (2006) Eur J Heart Fail , vol.8 , pp. 16-22
    • Yutao, X.1    Geru, W.2    Xiaojun, B.3    Tao, G.4    Aiqun, M.5
  • 45
    • 0037236642 scopus 로고    scopus 로고
    • a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
    • Brancaccio M, Fratta L, Notte A, Hirsch E, Poulet R, et al. (2003) a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. Nat Med 9: 68-75.
    • (2003) Nat Med , vol.9 , pp. 68-75
    • Brancaccio, M.1    Fratta, L.2    Notte, A.3    Hirsch, E.4    Poulet, R.5
  • 46
    • 0036129839 scopus 로고    scopus 로고
    • The mode of mechanical integrin stressing controls intracellular signaling in osteoblasts
    • Pommerenke H, Schmidt C, Dürr F, Nebe B, Lüthen F, et al. (2002) The mode of mechanical integrin stressing controls intracellular signaling in osteoblasts. J Bone Miner Res 17: 603-611.
    • (2002) J Bone Miner Res , vol.17 , pp. 603-611
    • Pommerenke, H.1    Schmidt, C.2    Dürr, F.3    Nebe, B.4    Lüthen, F.5
  • 47
    • 0036843301 scopus 로고    scopus 로고
    • Role of integrins in endothelial mechanosensing of shear stress
    • Shyy JY, Chien S, (2002) Role of integrins in endothelial mechanosensing of shear stress. Circulation Research 91: 769-775.
    • (2002) Circulation Research , vol.91 , pp. 769-775
    • Shyy, J.Y.1    Chien, S.2
  • 48
    • 0028972130 scopus 로고
    • Immunogold localization of beta 1-integrin in bone: effect of glucocorticoids and insulin-like growth factor I on integrins and osteocyte formation
    • Gohel AR, Hand AR, Gronowicz GA, (1995) Immunogold localization of beta 1-integrin in bone: effect of glucocorticoids and insulin-like growth factor I on integrins and osteocyte formation. J Histochem Cytochem 43: 1085-1096.
    • (1995) J Histochem Cytochem , vol.43 , pp. 1085-1096
    • Gohel, A.R.1    Hand, A.R.2    Gronowicz, G.A.3
  • 49
    • 0029257159 scopus 로고
    • The effects of mechanical stimulation on the distribution of beta 1-integrin and expression of beta 1-integrin mRNA in TE-85 human osteosarcoma cells
    • Carvalho RS, Scott JE, Yen EH, (1995) The effects of mechanical stimulation on the distribution of beta 1-integrin and expression of beta 1-integrin mRNA in TE-85 human osteosarcoma cells. Arch Oral Biol 40: 257-264.
    • (1995) Arch Oral Biol , vol.40 , pp. 257-264
    • Carvalho, R.S.1    Scott, J.E.2    Yen, E.H.3
  • 50
    • 6044235528 scopus 로고    scopus 로고
    • Mechanical anisotropy of adherent cells probed by a three-dimensional magnetic twisting device
    • Hu S, Eberhard L, Chen J, Love JC, Butler JP, et al. (2004) Mechanical anisotropy of adherent cells probed by a three-dimensional magnetic twisting device. Am J Physiol Cell Physiol 287: 1184-1191.
    • (2004) Am J Physiol Cell Physiol , vol.287 , pp. 1184-1191
    • Hu, S.1    Eberhard, L.2    Chen, J.3    Love, J.C.4    Butler, J.P.5
  • 51
    • 73649108263 scopus 로고    scopus 로고
    • Integrin activation dynamics between the RGD-binding site and the headpiece hinge
    • Puklin-Faucher E, Vogel V, (2009) Integrin activation dynamics between the RGD-binding site and the headpiece hinge. J Biol Chem 284 (52): 36557-68.
    • (2009) J Biol Chem , vol.284 , Issue.52 , pp. 36557-36568
    • Puklin-Faucher, E.1    Vogel, V.2
  • 52
    • 33646902229 scopus 로고    scopus 로고
    • Up-regulation of the Wnt, Estrogen Receptor, Insulin-like Growth Factor-I, and Bone Morphogenetic Protein Pathways in C57BL/6J Osteoblasts as Opposed to C3H/HeJ Osteoblasts in Part Contributes to the Differential Anabolic Response to Fluid Shear
    • Lau KH, Kapur S, Kesavan C, Baylink DJ, (2006) Up-regulation of the Wnt, Estrogen Receptor, Insulin-like Growth Factor-I, and Bone Morphogenetic Protein Pathways in C57BL/6J Osteoblasts as Opposed to C3H/HeJ Osteoblasts in Part Contributes to the Differential Anabolic Response to Fluid Shear. J Biol Chem 281: 9576-9588.
    • (2006) J Biol Chem , vol.281 , pp. 9576-9588
    • Lau, K.H.1    Kapur, S.2    Kesavan, C.3    Baylink, D.J.4
  • 53
    • 34447500137 scopus 로고    scopus 로고
    • Stretch-induced MAP kinase activation in cardiacmyocytes: Differential regulation through β1-integrin and focal adhesion kinase
    • Lal H, Verma SK, Smith M, Guleria RS, Lu G, et al. (2007) Stretch-induced MAP kinase activation in cardiacmyocytes: Differential regulation through β1-integrin and focal adhesion kinase. J Mol Cell Cardiol 43: 137-147.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 137-147
    • Lal, H.1    Verma, S.K.2    Smith, M.3    Guleria, R.S.4    Lu, G.5
  • 54
    • 73649139225 scopus 로고    scopus 로고
    • Oscillatory Flow-induced Proliferation of Osteoblast-like Cells Is Mediated by αvβ3 and β1 Integrins through Synergistic Interactions of Focal Adhesion Kinase and Shc with Phosphatidylinositol 3-Kinase and the Akt/mTOR/p70S6K Pathway
    • Lee DY, Li YS, Chang SF, Zhou J, Ho HM, et al. (2010) Oscillatory Flow-induced Proliferation of Osteoblast-like Cells Is Mediated by αvβ3 and β1 Integrins through Synergistic Interactions of Focal Adhesion Kinase and Shc with Phosphatidylinositol 3-Kinase and the Akt/mTOR/p70S6K Pathway. J Biol Chem 285: 30-42.
    • (2010) J Biol Chem , vol.285 , pp. 30-42
    • Lee, D.Y.1    Li, Y.S.2    Chang, S.F.3    Zhou, J.4    Ho, H.M.5
  • 55
    • 33846439393 scopus 로고    scopus 로고
    • Extracellular Matrix-mediated Tissue Remodeling Following Axial Movement of Teeth
    • Luan X, Ito Y, Holliday S, Walker C, Daniel J, et al. (2007) Extracellular Matrix-mediated Tissue Remodeling Following Axial Movement of Teeth. J Histochem Cytochem 55: 127-140.
    • (2007) J Histochem Cytochem , vol.55 , pp. 127-140
    • Luan, X.1    Ito, Y.2    Holliday, S.3    Walker, C.4    Daniel, J.5
  • 56
    • 78651231027 scopus 로고    scopus 로고
    • Involvement of BMPs/Smad Signaling Pathway inMechanical Response in Osteoblasts
    • Wang L, Zhang X, Guo Y, Chen X, Li R, et al. (2010) Involvement of BMPs/Smad Signaling Pathway inMechanical Response in Osteoblasts. Cell Physiol Biochem 26: 1093-1102.
    • (2010) Cell Physiol Biochem , vol.26 , pp. 1093-1102
    • Wang, L.1    Zhang, X.2    Guo, Y.3    Chen, X.4    Li, R.5
  • 57
    • 33747203059 scopus 로고    scopus 로고
    • Early responses of osteoblast-like cells to different mechanical signals through various signaling pathways
    • Liu J, Liu T, Zheng Y, Zhao Z, Liu Y, et al. (2006) Early responses of osteoblast-like cells to different mechanical signals through various signaling pathways. Biochem Biophys Res Commun 348: 1167-1173.
    • (2006) Biochem Biophys Res Commun , vol.348 , pp. 1167-1173
    • Liu, J.1    Liu, T.2    Zheng, Y.3    Zhao, Z.4    Liu, Y.5
  • 58
    • 0030846047 scopus 로고    scopus 로고
    • Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain
    • Owan I, Burr DB, Turner CH, Qiu J, Tu Y, et al. (1997) Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain. Am J Physiol 273: C810-815.
    • (1997) Am J Physiol , vol.273
    • Owan, I.1    Burr, D.B.2    Turner, C.H.3    Qiu, J.4    Tu, Y.5
  • 59
    • 34447319602 scopus 로고    scopus 로고
    • Decreased CD90 expression in human mesenchymal stem cells by applying mechanical stimulation
    • Wiesmann A, Buhring HJ, Mentrup C, Wiesmann HP, (2006) Decreased CD90 expression in human mesenchymal stem cells by applying mechanical stimulation. Head Face Med 2: 8.
    • (2006) Head Face Med , vol.2 , pp. 8
    • Wiesmann, A.1    Buhring, H.J.2    Mentrup, C.3    Wiesmann, H.P.4
  • 60
    • 27144488205 scopus 로고    scopus 로고
    • Tetrazolium dyes as tools in cell biology: New insights into their cellular reduction
    • Berridge MV, Tan AS, Herst PM, (2005) Tetrazolium dyes as tools in cell biology: New insights into their cellular reduction. Biotechnology Annual Review 11: 127-152.
    • (2005) Biotechnology Annual Review , vol.11 , pp. 127-152
    • Berridge, M.V.1    Tan, A.S.2    Herst, P.M.3
  • 61
    • 33748491718 scopus 로고    scopus 로고
    • Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project
    • Patterson TA, Lobenhofer EK, Fulmer-Smentek SB, Collins PJ, Chu TM, et al. (2006) Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project. Nat Biotechnol 24: 1140-1150.
    • (2006) Nat Biotechnol , vol.24 , pp. 1140-1150
    • Patterson, T.A.1    Lobenhofer, E.K.2    Fulmer-Smentek, S.B.3    Collins, P.J.4    Chu, T.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.