Passage-affected competitive regulation of osteoprotegerin synthesis and the receptor activator of nuclear factor-κB ligand mRNA expression in normal human osteoblasts stimulated by the application of cyclic tensile strain

Journal of Bone and Mineral Metabolism

Volumn 27, Issue 6, 2009, Pages 653-662

  Kusumi, Akinori ^a   Kusumi, Tomomi ^b   Miura, Jun ^a   Tateishi, Tomonori ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b AOMORI PREFECTURAL CENTRAL HOSPITAL   (Japan)

Author keywords

Cyclic tensile strain; Mitogen activated protein kinase; Number of passages; Osteoblasts; Osteoprotegerin

Indexed keywords

CYCLOOXYGENASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPONTIN; OSTEOPROTEGERIN;

ARTICLE; BONE REMODELING; BONE TISSUE; CELL AGING; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; MECHANICAL STRESS; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TISSUE ENGINEERING;

BONE AND BONES; CELL AGING; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION; HUMANS; MAP KINASE SIGNALING SYSTEM; NITRIC OXIDE; NITRITES; OSTEOBLASTS; OSTEOPROTEGERIN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RANK LIGAND; RNA, MESSENGER; STRESS, MECHANICAL; TENSILE STRENGTH; TISSUE ENGINEERING;

EID: 70449526309     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00774-009-0085-3     Document Type: Article

References (42)

1. TM Skerry 1999 Identification of novel signalling pathways during functional adaptation of the skeleton to mechanical loading: the role of glutamate as a paracrine signalling agent in the skeleton J Bone Miner Metab 17 66 70 10.1007/s007740050067 1:CAS:528:DyaK1MXislKltbw%3D 10084405 (Pubitemid 29117756)
2. Y Mikuni-Takagaki 1999 Mechanical responses and signal transduction pathways in stretched osteocytes J Bone Miner Metab 17 57 60 10.1007/s007740050065 1:STN:280:DyaK1M7otFyqtg%3D%3D 10084403 (Pubitemid 29117754)
3. R Huiskes R Ruimerman GH van Lenthe JD Janssen 2000 Effects of mechanical forces on maintenance and adaptation of form in trabecular bone Nature (Lond) 405 704 706 10.1038/35015116 1:CAS:528:DC%2BD3cXktlGnsbo%3D (Pubitemid 30428659)
4. Y Azuma M Ito Y Harada H Takagi T Ohta S Jingushi 2001 Low-intensity pulsed ultrasound accelerates rat femoral fracture healing by acting on the various cellular reactions in the fracture callus J Bone Miner Res 16 671 680 10.1359/jbmr.2001.16.4.671 1:STN:280:DC%2BD3MvlvFKrug%3D%3D 11315994
5. L Vico M Hinsenkamp D Jones PJ Marie A Zallone R Cancedda 2001 Osteobiology, strain, and microgravity. Part II: studies at the tissue level Calcif Tissue Int 68 1 10 10.1007/BF02684996 1:CAS:528:DC%2BD3MXkvFers74%3D 12037617
6. L Hayflick PS Moorhead 1961 The serial cultivation of human diploid cell strains Exp Cell Res 25 585 621 10.1016/0014-4827(61)90192-6
7. VJ Cristofalo A Lorenzini RG Allen C Torres M Tresini 2004 Replicative senescence: a critical review Mech Ageing Dev 125 827 848 10.1016/j.mad.2004.07. 010 1:CAS:528:DC%2BD2cXpslGmsr0%3D 15541776 (Pubitemid 39485238)
8. CB Harley AB Futcher CW Greider 1990 Telomeres shorten during ageing of human fibroblasts Nature (Lond) 345 458 460 10.1038/345458a0 1:CAS:528:DyaK3cXksFKntb4%3D (Pubitemid 20178256)
9. VJ Cristofalo RG Allen RJ Pignolo BG Martin JC Beck 1998 Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation Proc Natl Acad Sci USA 95 10614 10619 10.1073/pnas.95.18.10614 1:CAS:528:DyaK1cXlvFWgtro%3D 9724752 (Pubitemid 28413116)
10. H Kamino M Hiratsuka T Toda R Nishigaki M Osaki H Ito T Inoue M Oshimura 2003 Searching for genes involved in arteriosclerosis: proteomic analysis of cultured human umbilical vein endothelial cells undergoing replicative senescence Cell Struct Funct 28 495 503 10.1247/csf.28.495 1:CAS:528: DC%2BD2cXjs1WgtbY%3D 15004419 (Pubitemid 38519421)
11. Q Shi K Aida JL Vandeberg XL Wang 2004 Passage-dependent changes in baboon endothelial cells: relevance to in vitro aging DNA Cell Biol 23 502 509 10.1089/1044549041562294 1:CAS:528:DC%2BD2cXmt1Wqtbs%3D 15307953 (Pubitemid 39050556)
12. A Kusumi H Sakaki T Kusumi M Oda K Narita H Nakagawa K Kubota H Kimura 2005 Regulation of synthesis of osteoprotegerin and soluble receptor activator of nuclear factor-κB ligand in normal human osteoblasts via the p38 mitogen-activated protein kinase pathway by the application of cyclic tensile strain J Bone Miner Metab 23 373 381 10.1007/s00774-005-0615-6 1:CAS:528:DC%2BD2MXovVOitbg%3D 16133687 (Pubitemid 41223800)
13. N Boutahar A Guignandon L Vico MH Lafage-Proust 2004 Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation J Biol Chem 279 30588 30599 10.1074/jbc.M313244200 1:CAS:528:DC%2BD2cXlsFKhs7o%3D 15096502 (Pubitemid 38937991)
14. L Tang Z Lin YM Li 2006 Effects of different magnitudes of mechanical strain on osteoblasts in vitro Biochem Biophys Res Commun 344 122 128 10.1016/j.bbrc.2006.03.123 1:CAS:528:DC%2BD28XjvFWns7w%3D 16603128
15. MM Saunders AF Taylor C Du Z Zhou VD Pellegrini Jr HJ Donahue 2006 Mechanical stimulation effects on functional end effectors in osteoblastic MG-63 cells J Biomech 39 1419 1427 10.1016/j.jbiomech.2005.04.011 1:STN:280:DC%2BD283nt1Gqsg%3D%3D 15953606
16. S Khosla 2001 Minireview: the OPG/RANKL/RANK system Endocrinology 142 5050 5055 10.1210/en.142.12.5050 1:CAS:528:DC%2BD3MXovVSntb8%3D 11713196 (Pubitemid 33131929)
17. LC Hofbauer AE Heufelder 2001 Role of receptor activator of nuclear factor-κB ligand and osteoprotegerin in bone cell biology J Mol Med 79 243 253 10.1007/s001090100226 1:CAS:528:DC%2BD3MXlslWgt78%3D 11485016 (Pubitemid 32646379)
18. M Morinobu M Ishijima SR Rittling K Tsuji H Yamamoto A Nifuji DT Denhardt M Noda 2003 Osteopontin expression in osteoblasts and osteocytes during bone formation under mechanical stress in the calvarial suture in vivo J Bone Miner Res 18 1706 1715 10.1359/jbmr.2003.18.9.1706 1:CAS:528:DC%2BD3sXnsVymu7k%3D 12968681 (Pubitemid 37022930)
19. M Watanuki A Sakai T Sakata H Tsurukami M Miwa Y Uchida K Watanabe K Ikeda T Nakamura 2002 Role of inducible nitric oxide synthase in skeletal adaptation to acute increases in mechanical loading J Bone Miner Res 17 1015 1025 10.1359/jbmr.2002.17.6.1015 1:CAS:528:DC%2BD38Xks1Wktb4%3D 12054156
20. K Nakai S Tanaka A Sakai M Nagashima M Tanaka H Otomo T Nakamura 2006 Cyclooxygenase-2 selective inhibition suppresses restoration of tibial trabecular bone formation in association with restriction of osteoblast maturation in skeletal reloading after hindlimb elevation of mice Bone (NY) 39 83 92 1:CAS:528:DC%2BD28Xls1ejt74%3D
21. CM Yang CS Chien CC Yao LD Hsiao YC Huang CB Wu 2004 Mechanical strain induces collagenase-3 (MMP-13) expression in MC3T3-E1 osteoblastic cells J Biol Chem 279 22158 22165 10.1074/jbc.M401343200 1:CAS:528:DC%2BD2cXjvF2rsL0%3D 15044466 (Pubitemid 38679409)
22. J Liu T Liu Y Zheng Z Zhao Y Liu H Cheng S Luo Y Chen 2006 Early responses of osteoblast-like cells to different mechanical signals through various signalling pathways Biochem Biophys Res Commun 348 1167 1173 10.1016/j.bbrc.2006.07.175 1:CAS:528:DC%2BD28XosVOisLs%3D 16904072 (Pubitemid 44233536)
23. A Kusumi H Sakaki R Fukui H Satoh T Kusumi H Kimura 2004 High IL-6 synthesis in cultured fibroblasts isolated from radicular cysts Arch Oral Biol 49 643 652 10.1016/j.archoralbio.2004.02.006 1:CAS:528:DC%2BD2cXkvVCls7g%3D 15196982 (Pubitemid 38791604)
24. T Kusumi Y Ishibashi E Tsuda A Kusumi M Tanaka F Sato S Toh H Kijima 2006 Osteochondritis dissecans of the elbow: histopathologic assessment of the articular cartilage and subchondral bone with special emphasis on their damage and repair Pathol Int 56 604 612 10.1111/j.1440-1827.2006.02015.x 16984617 (Pubitemid 44423019)
25. Z Xu MJ Buckley CH Evans S Agarwal 2000 Cyclic tensile strain acts as an antagonist of IL-1β actions in chondrocytes J Immunol 165 453 460 1:CAS:528:DC%2BD3cXksVKlt7g%3D 10861084
26. I Bièche I Laurendeau S Tozlu M Olivi D Vidaud R Lidereau M Vidaud 1999 Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay Cancer Res 59 2759 2765 10383126
27. S Chretien A Dubart D Beaupain N Raich B Grandchamp J Rosa M Goossens P-H Romeo 1988 Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression Proc Natl Acad Sci USA 85 6 10 10.1073/pnas.85.1.6 1:CAS:528:DyaL1cXht1Glt7k%3D 3422427
28. N Shimizu T Goseki M Yamaguchi T Iwasawa H Takiguchi Y Abiko 1997 In vitro cellular aging stimulates interleukin-1β production in stretched human periodontal-ligament-derived cells J Dent Res 76 1367 1375 10.1177/00220345970760070601 1:CAS:528:DyaK2sXks1Oitbw%3D 9207769
29. Y Abiko N Shimizu M Yamaguchi H Suzuki H Takiguchi 1998 Effect of aging on functional changes of periodontal tissue cells Ann Periodontol 3 350 356 1:STN:280:DyaK1czovF2nsQ%3D%3D 9722719
30. E Terpos R Szydlo JF Apperley E Hatjiharissi M Politou J Meletis N Viniou X Yataganas JM Goldman A Rahemtulla 2003 Soluble receptor activator of nuclear factor κB ligand-osteoprotegerin ratio predicts survival in multiple myeloma: proposal for a novel prognostic index Blood 102 1064 1069 10.1182/blood-2003-02-0380 1:CAS:528:DC%2BD3sXlvFCmt7Y%3D 12689925 (Pubitemid 36917805)
31. B Pan AN Farrugia LB To DM Findlay J Green K Lynch AC Zannettino 2004 The nitrogen-containing bisphosphonate, zoledronic acid, influences RANKL expression in human osteoblast-like cells by activating TNF-α converting enzyme (TACE) J Bone Miner Res 19 147 154 10.1359/jbmr.2004.19.1.147 1:CAS:528:DC%2BD2cXnt1Kgug%3D%3D 14753746 (Pubitemid 41295147)
32. T Kanno T Takahashi T Tsujisawa W Ariyoshi T Nishihara 2007 Mechanical stress-mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signalling in osteoblasts J Cell Biochem 101 1266 1277 10.1002/jcb.21249 1:CAS:528: DC%2BD2sXptFKgs7c%3D 17265428 (Pubitemid 47253725)
33. BT Andresen MA Rizzo K Shome G Romero 2002 The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signalling cascade FEBS Lett 531 65 68 10.1016/S0014-5793(02)03483-X 1:CAS:528:DC%2BD38XotVOjtLc%3D 12401205 (Pubitemid 35232787)
34. E Hütter H Unterluggauer F Überall H Schramek P Jansen-Dürr 2002 Replicative senescence of human fibroblasts: the role of Ras-dependent signalling and oxidative stress Exp Gerontol 37 1165 1174 10.1016/S0531-5565(02)00136-5 12470828 (Pubitemid 35418274)
35. ME Carlson HS Silva IM Conboy 2008 Aging of signal transduction pathways, and pathology Exp Cell Res 314 1951 1961 10.1016/j.yexcr.2008.03.017 1:CAS:528:DC%2BD1cXlslOru74%3D 18474281 (Pubitemid 351649367)
36. H Iwasa J Han F Ishikawa 2003 Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway Genes Cells 8 131 144 10.1046/j.1365-2443.2003.00620.x 1:CAS:528:DC%2BD3sXht1amsrg%3D 12581156 (Pubitemid 36511698)
37. M Shakibaei C Seifarth T John M Rahmanzadeh A Mobasheri 2006 Igf-I extends the chondrogenic potential of human articular chondrocytes in vitro: molecular association between Sox9 and Erk1/2 Biochem Pharmacol 72 1382 1395 10.1016/j.bcp.2006.08.022 1:CAS:528:DC%2BD28XhtFOjtrbI 17010943 (Pubitemid 44666750)
38. J Cao L Venton T Sakata BP Halloran 2003 Expression of RANKL and OPG correlates with age-related bone loss in male C57BL/6 mice J Bone Miner Res 18 270 277 10.1359/jbmr.2003.18.2.270 1:CAS:528:DC%2BD3sXht1Sktr4%3D 12568404 (Pubitemid 36125919)
39. JJ Cao TJ Wronski U Iwaniec L Phleger P Kurimoto B Boudignon BP Halloran 2005 Aging increases stromal/osteoblastic cell-induced osteoclastogenesis and alters the osteoclast precursor pool in the mouse J Bone Miner Res 20 1659 1668 10.1359/JBMR.050503 1:CAS:528:DC%2BD2MXhtVOltrjF 16059637 (Pubitemid 41243554)
40. F Sugiura H Kitoh N Ishiguro 2004 Osteogenic potential of rat mesenchymal stem cells after several passages Biochem Biophys Res Commun 316 233 239 10.1016/j.bbrc.2004.02.038 1:CAS:528:DC%2BD2cXhslentLo%3D 15003535 (Pubitemid 38299150)
41. JR Mauney C Jaquiery V Volloch M Heberer I Martin DL Kaplan 2005 In vitro and in vivo evaluation of differentially demineralized cancellous bone scaffolds combined with human bone marrow stromal cells for tissue engineering Biomaterials 26 3173 3185 10.1016/j.biomaterials.2004.08.020 1:CAS:528:DC%2BD2cXhtVyrsL%2FO 15603812 (Pubitemid 39647252)
42. L O'Driscoll P Gammell E McKiernan E Ryan PB Jeppesen S Rani M Clynes 2006 Phenotypic and global gene expression profile changes between low passage and high passage MIN-6 cells J Endocrinol 191 665 676 10.1677/joe.1.06894 17170223 (Pubitemid 46210291)