Establishment of a Method for Analyzing Translesion DNA Synthesis across a Single Bulky Adduct in Human Cells

Genes and Environment

Volumn 31, Issue 1, 2009, Pages 24-30

  Sawai, Tomoko ^a   Kawanishi, Masanobu ^a   Takamura Enya, Takeji ^b   Yagi, Takashi ^a  

^a Osaka Prefecture University   (Japan)

^b KANAGAWA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84859946593     PISSN: 18807046     EISSN: 18807062     Source Type: Journal    
DOI: 10.3123/jemsge.31.24     Document Type: Article

References (44)

1. Yang I, Johnson F, Grollman A, Moriya M. Genotoxic mechanism for the major acrolein-derived deoxyguano-sine adduct in human cells. Chem Res Toxicol. 2002; 15: 160-4.
2. Stein S, Lao Y, Yang I, Hecht S, Moriya M. Genotoxicity of acetaldehyde-and crotonaldehyde-induced 1,N2-propanodeoxyguanosine DNA adducts in human cells. Mutat Res. 2006; 608: 1-7.
3. Avkin S, Goldsmith M, Velasco-Miguel S, Geacintov N, Friedberg E, Livneh Z. Quantitative analysis of transle-sion DNA synthesis across a benzo[a]pyrene-guanine ad-duct in mammalian cells: the role of DNA polymerase kappa. J Biol Chem. 2004; 279: 53298-305.
4. Friedberg EC. Suffering in silence: The tolerance of DNA damage. Nat Rev Mol Cell Biol. 2005; 6: 943-53.
5. Goodman MF. Error-prone repair DNA polymerases in prokaryotes and eukaryotes. Ann Rev Biochem. 2002; 71: 17-50.
6. Lehmann AR. Replication of damaged DNA by transle-sion synthesis in human cells. FEBS Lett. 2005; 579: 873-6.
7. Lehmann AR. Translesion synthesis in mammalian cells.Exp Cell Res. 2006; 312: 2673-6.
8. Rattray A, Strathern J. Error-prone DNA polymerases: when making a mistake is the only way to get ahead. Annu Rev Genet. 2003; 37: 31-66.
9. Vaisman A, Lehmann AR, Woodgate R. DNA polymerases eta and iota. Adv Protein Chem. 2004; 69: 205-28.
10. Lehmann AR, Niimi A, Ogi T, Brown S, Sabbioneda S, Wing J, Kannouche P, Green C. Translesion synthesis: Y-family polymerases and the polymerase switch. DNA Repair (Amst). 2007; 6: 891-9.
11. Sharief F, Vojta P, Ropp P, Copeland W. Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase. Genomics. 1999; 59: 90-6.
12. Garcia-Diaz M, Dominguez O, Lijpez-Fernndez L, de Lera L, Saniger M, Ruiz J, Prraga M. DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA poly-merase with a potential role in meiosis. J Mol Biol. 2000; 301: 851-67.
13. Marini F, Kim N, Schuffert A, Wood R. POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308. J Biol Chem. 2003; 278: 32014-9.
14. Lenne-Samuel N, Janel-Bintz R, Kolbanovskiy A, Gea-cintov N, Fuchs R. The processing of a Benzo(a)pyrene adduct into a frameshift or a base substitution mutation requires a different set of genes in Escherichia coli. Mol Microbiol. 2000; 38: 299-307.
15. Zhang Y, Yuan F, Wu X, Wang M, Rechkoblit O, Taylor J, Geacintov N, Wang Z. Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro. Nucleic Acids Res. 2000; 28: 4138-46.
16. Suzuki N, Ohashi E, Kolbanovskiy A, Geacintov N, Grollman A, Ohmori H, Shibutani S. Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-( + )-or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-[7,8,9,10]-tetrahydrobenzo[a]pyrene). Biochemistry. 2002; 41: 6100-6.
17. Zhang Y, Yuan F, Wu X, Rechkoblit O, Taylor J, Gea-cintov N, Wang Z. Error-prone lesion bypass by human DNA polymerase eta. Nucleic Acids Res. 2000; 28: 4717-24.
18. Koffel-Schwartz N, Coin F, Veaute X, Fuchs R. Cellular strategies for accommodating replication-hindering ad-ducts in DNA: control by the SOS response in Escherichia coli. Proc Natl Acad Sci USA. 1996; 93: 7805-10.
19. Veaute X, Fuchs R. Greater susceptibility to mutations in lagging strand of DNA replication in Escherichia coli than in leading strand. Science. 1993; 261: 598-600.
20. Schulte PA, Ward E, Boeniger M. and Mills B. (Ed). Occupational exposure to N-substituted aryl compounds. New York: Elsevier 1988.
21. Napolitano R, Janel-Bintz R, Wagner J, Fuchs R. All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis. EMBO J. 2000; 19: 6259-65.
22. lARC. lARC Monographs on the Evaluation of the Car-cinogenic Risk of Chemicals to Humans. Tobacco Smoking. Vol. 38. Lyon.: lARC Scientific Publications 1986.
23. Haugen DAP, Meyrick J. Suhrbier, Katherine M. Stamoudis, Vassilis C. Isolation of mutagenic aromatic amines from a coal conversion oil by cation exchange chro-matography. Anal Chem. 1982; 54: 32-37.
24. Steineck G, Plato N, Norell S, Hogstedt C. Urothelial cancer and some industry-related chemicals: an evaluation of the epidemiologic literature. Am J Ind Med. 1990; 17: 371-91.
25. Vineis P. Epidemiology of cancer from exposure to aryla-mines. Environ Health Perspect. 1994; 102: 7-10.
26. Feng Z, Hu W, Rom W, Beland F, Tang M. 4-aminobiphenyl is a major etiological agent of human bladder cancer: evidence from its DNA binding spectrum in human p53 gene. Carcinogenesis. 2002; 23: 1721-7.
27. Protić-Sabljić M, Seetharam S, Seidman M, Kraemer K. An SV40-transformed xeroderma pigmentosum group D cell line: establishment, ultraviolet sensitivity, transfec-tion efficiency and plasmid mutation induction. Mutat Res. 1986; 166: 287-94.
28. Matsuda T, Yagi T, Kawanishi M, Matsui S, Takebe H. Molecular analysis of mutations induced by 2-chloro-acetaldehyde, the ultimate carcinogenic form of vinyl chloride, in human cells using shuttle vectors. Carcino-genesis. 1995; 16: 2389-94.
29. Böge N, Gräsl S, Meier C. Synthesis and properties of oligonucleotides containing C8-deoxyguanosine aryl-amine adducts of borderline carcinogens. J Org Chem. 2006; 71: 9728-38.
30. Takamura-Enya T, Ishikawa S, Mochizuki M, Wakabayashi K. A practical approach for the chemical synthesis of 2-deoxyguanosine-C8 adducts with mutageniccarcinogenic amino-or nitro-arenes. Tetrahedron Letters. 2003; 44: 5969-73.
31. Avkin S, Adar S, Blander G, Livneh Z. Quantitative measurement of translesion replication in human cells: evidence for bypass of abasic sites by a replicative DNA polymerase. Proc Natl Acad Sci USA. 2002; 99: 3764-9.
32. Hendel A, Ziv O, Gueranger Q, Geacintov N, Livneh Z. Reduced efficiency and increased mutagenicity of transle-sion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase eta. DNA Repair (Amst). 2008; 7: 1636-46.
33. Moriya M. Single-stranded shuttle phagemid for muta-genesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C→T.A transversions in simian kidney cells. Proc Natl Acad Sci USA. 1993; 90: 1122-6.
34. Moriya M, Spiegel S, Fernandes A, Amin S, Liu T, Gea-cintov N, Grollman A. Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality. Biochemistry. 1996; 35: 16646-51.
35. Levine R, Yang I, Hossain M, Pandya G, Grollman A, Moriya M. Mutagenesis induced by a single 1,N6-ethenodeoxyadenosine adduct in human cells. Cancer Res. 2000; 60: 4098-104.
36. Yang I, Miller H, Wang Z, Frank E, Ohmori H, Hanao-ka F, Moriya M. Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells. J Biol Chem. 2003; 278: 13989-94.
37. Yasui M, Dong H, Bonala RR, Suzuki N, Ohmori H, Hanaoka F, Johnson F, Grollman AP, Shibutani S. Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells. Biochemistry. 2004; 43: 15005-13.
38. Hoege C, Pfander B, Moldovan G, Pyrowolakis G, Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature. 2002; 419: 135-41.
39. Stelter P, Ulrich H. Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature. 2003; 425: 188-91.
40. Haracska L, Torres-Ramos C, Johnson R, Prakash S, Prakash L. Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae. Mol Cell Biol.2004; 24: 4267-74.
41. Bienko M, Green C, Crosetto N, Rudolf F, Zapart G, Coull B, Kannouche P, Wider G, Peter M, Lehmann AR, Hofmann K, Dikic I. Ubiquitin-binding domains in Y-fa-mily polymerases regulate translesion synthesis. Science. 2005; 310: 1821-4.
42. Wood A, Garg P, Burgers P. A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage. J Biol Chem. 2007; 282: 20256-63.
43. Plosky B, Vidal A, Fernandez de Henestrosa A, McLeni-gan M, McDonald J, Mead S, Woodgate R. Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin. EMBO J. 2006; 25: 2847-55.
44. Watanabe K, Tateishi S, Kawasuji M, Tsurimoto T, In-oue H, Yamaizumi M. Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination. EMBO J. 2004; 23: 3886-96.