Insights into the mechanism of pore opening of acid-sensing ion channel 1A

Journal of Biological Chemistry

Volumn 286, Issue 18, 2011, Pages 16297-16307

  Tolino, Lindsey A ^a   Okumura, Sora ^a   Kashlan, Ossama B ^a   Carattino, Marcelo D ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-SENSING ION CHANNELS; CATION CHANNELS; DESENSITIZED STATE; DISULFIDE BONDS; EXTRACELLULAR; EXTRACELLULAR REGION; METHANETHIOSULFONATE; MUTANT CYCLE; PORE OPENINGS; PROTON BINDING; SIDE CHAINS; SPATIAL CONSTRAINTS; TRANSMEMBRANES; UNDERLYING MECHANISM;

ACIDIFICATION; AMINO ACIDS; COVALENT BONDS;

IONS;

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; AMINO ACID; CYSTEINE; DISULFIDE; GLYCINE; MONOMER; THIOMESYLIC ACID METHYL ESTER; TYROSINE; UNCLASSIFIED DRUG;

ACIDIFICATION; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISULFIDE BOND; EXTRACELLULAR SPACE; ION CONDUCTANCE; MEMBRANE TRANSPORT; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; ANIMALS; DISULFIDES; INDICATORS AND REAGENTS; ION TRANSPORT; MESYLATES; MICE; MUTAGENESIS; MUTATION, MISSENSE; NERVE TISSUE PROTEINS; PROTEIN STRUCTURE, TERTIARY; SODIUM CHANNELS; XENOPUS LAEVIS;

EID: 79955546832     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.202366     Document Type: Article

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