Riluzole produces distinct anxiolytic-like effects in rats without the adverse effects associated with benzodiazepines

Neuropharmacology

Volumn 62, Issue 8, 2012, Pages 2489-2498

  Sugiyama, Azusa ^a,b   Saitoh, Akiyoshi ^a   Iwai, Takashi ^a   Takahashi, Kou ^a   Yamada, Misa ^a   Sasaki Hamada, Sachie ^b   Oka, Jun Ichiro ^b   Inagaki, Masatoshi ^a   Yamada, Mitsuhiko ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Behavioral; Elevated plus maze; GABA; Glutamate; Veratrine

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE RECEPTOR; CEVADINE; DIAZEPAM; RILUZOLE; SODIUM CHANNEL;

ADVERSE DRUG REACTION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ETHANOL INDUCED SLEEPING TIME TEST; EXPERIMENTAL TEST; FOOTPRINT ANALYSIS; MALE; MAZE TEST; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; RAT; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BEHAVIOR, ANIMAL; BENZODIAZEPINES; DIAZEPAM; EXPLORATORY BEHAVIOR; MALE; MOTOR ACTIVITY; RATS; RATS, WISTAR; RILUZOLE;

EID: 84859711158     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.02.012     Document Type: Article

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