The metabotropic glutamate receptor subtype 5 antagonist MPEP and the Na+ channel blocker riluzole show different neuroprotective profiles in reversing behavioral deficits induced by excitotoxic prefrontal cortex lesions

Neuroscience

Volumn 137, Issue 1, 2006, Pages 211-220

  Risterucci, C ^a   Coccurello, R ^a   Banasr, M ^b   Stutzmann, J M ^c   Amalric, M ^a   Nieoullon, A ^b  

^a AIX MARSEILLE UNIVERSITÉ   (France)

^b CNRS   (France)

^c SANOFI   (France)

Author keywords

Cell survival; Ibotenic acid; MPEP; Neuroprotection; Reaction time task; Riluzole

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; AMINO ACID; IBOTENIC ACID; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; NEUROPROTECTIVE AGENT; NUCLEAR PROTEIN; RILUZOLE; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN CORTEX; BRAIN DAMAGE; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; EXCITOTOXICITY; IMMUNOHISTOCHEMISTRY; MALE; NEUROPROTECTION; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; REACTION TIME;

ANIMALS; BRAIN INJURIES; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; IBOTENIC ACID; MALE; MENTAL DISORDERS; NEUROPROTECTIVE AGENTS; PREFRONTAL CORTEX; PYRIDINES; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; RILUZOLE;

EID: 29744445316     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.08.054     Document Type: Article

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