Berberine inhibits pulmonary metastasis through down-regulation of MMP in metastatic B16F-10 melanoma cells

Phytotherapy Research

Volumn 26, Issue 4, 2012, Pages 568-578

  Hamsa, T P ^a,b   Kuttan, Girija ^a  

^a AMALA CANCER RESEARCH CENTRE   (India)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

B16F 10 melanoma cells; berberine; extracellular matrix; invasion; matrix metalloproteinases; proliferation

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; BERBERINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GELATINASE A; GELATINASE B; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEXOSAMINE; HYDROXYPROLINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NUCLEOSIDE DIPHOSPHATE KINASE NM23; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN LYSINE 6 OXIDASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; URONIC ACID; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CANCER INHIBITION; CANCER SURVIVAL; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; IN VITRO STUDY; INHIBITION KINETICS; LUNG METASTASIS; MELANOMA CELL; METASTASIS INHIBITION; MMP GENE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BERBERINE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; LUNG NEOPLASMS; MALE; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NF-KAPPA B;

MURINAE; MUS;

EID: 84859612867     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3586     Document Type: Article

References (53)

1. Albini A, Iwamoto Y, Kleinman HK, et al,. 1987. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 47: 3239-3245.
2. Bergman I, Loxley R,. 1970. The determination of hydroxyproline in urine hydrolysates. Clin Chim Acta 27: 347-349.
3. Billings PC, Habres JM, Liao DC, Tuttle SW,. 1991. Human fibroblasts contain a proteolytic activity which is inhibited by the Bowman-Birk protease inhibitor. Cancer Res 51: 5539-5543.
4. Bitter T, Muir HM,. 1962. A modified uronic acid carbazole reaction. Anal Biochem 4: 330-334.
5. Budhu A, Wang XW,. 2006. The role of cytokines in hepatocellular carcinoma. J Leukoc Biol 80: 1197-1213.
6. Campling BG, Pym J, Baker HM, Cole SP, Lam YM,. 1991. Chemosensitivity testing of small cell lung cancer using the MTT assay. Br J Cancer 63: 75-83.
7. Choi MA, Kim SH, Chung WY, Hwang JK, Park KK,. 2005. Xanthorrhizol, a natural sesquiterpenoid from Curcuma xanthorrhiza, has an anti-metastatic potential in experimental mouse lung metastasis model. Biochem Biophys Res Commun 326: 210-217.
8. Chomczynski P, Sacchi N,. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159.
9. Chuang MJ, Sun KH, Tang SJ, et al,. 2008. Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells. Cancer Sci 99: 905-913.
10. Cole SP,. 1986. Rapid chemosensitivity testing of human lung tumor cells using the MTT assay. Cancer Chemother Pharmacol 17: 259-263.
11. Deryugina EI, Quigley JP,. 2006. Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 25: 9-34.
12. Dignam JD, Lebovitz RM, Roeder RG,. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11: 1475-1489.
13. Dong G, Chen Z, Kato T, Van Waes C,. 1999. The host environment promotes the constitutive activation of nuclear factor-kappaB and pro-inflammatory cytokine expression during metastatic tumor progression of murine squamous cell carcinoma. Cancer Res 59: 3495-3504.
14. Duffy MJ, McGowan PM, Gallagher WM,. 2008. Cancer invasion and metastasis: changing views. J Pathol 214: 283-293.
15. Elson LA, Morgan WT,. 1933. A colorimetric method for the determination of glucosamine and chondrosamine. Biochem J 27: 1824-1828.
16. Erler JT, Giaccia AJ,. 2006. Lysyl oxidase mediates hypoxic control of metastasis. Cancer Res 66: 10238-10241.
17. Genersch E, Hayess K, Neuenfeld Y, Haller H,. 2000. Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: involvement of Ras-dependent and -independent pathways. J Cell Sci 113: 4319-4330.
18. Guruvayoorappan C, Kuttan G,. 2008. Amentoflavone inhibits experimental tumor metastasis through a regulatory mechanism involving MMP-2, MMP-9, prolyl hydroxylase, lysyl oxidase, VEGF, ERK-1, ERK-2, STAT-1, NM23 and cytokines in lung tissues of C57BL/6 mice. Immunopharmacol Immunotoxicol 30: 711-727.
19. HemaIswarya S, Doble M,. 2006. Potential synergism of natural products in the treatment of cancer. Phytother Res 20: 239-249.
20. Hill LL, Perussia B, McCue PA, Korngold R,. 1994. Effect of human natural killer cells on the metastatic growth of human melanoma xenografts in mice with severe combined immunodeficiency. Cancer Res 54: 763-770.
21. Ho YT, Yang JS, Li TC, et al,. 2009. Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-kappaB, u-PA and MMP-2 and -9. Cancer Lett 279: 155-162.
22. Hong WK, Sporn MB,. 1997. Recent advances in chemoprevention of cancer. Science 278: 1073-1077.
23. Jean D, Bar-Eli M,. 2000. Regulation of tumor growth and metastasis of human melanoma by the CREB transcription factor family. Mol Cell Biochem 212: 19-28.
24. Johnson SM, Wang X, Mark EB,. 2011. Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors. J Surg Res 168: 197-205.
25. Kagan HM, Li W,. 2003. Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell. J Cell Biochem 88: 660-672.
26. Lazar-Molnar E, Hegyesi H, Toth S, Falus A,. 2000. Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine 12: 547-554.
27. Lee EJ, Shin I, Kwon SK, Shin HS, Moon A,. 2003. Chemopreventive allylthiopyridazines inhibit invasion, migration and angiogenesis in hepatocarcinoma cells. Int J Oncol 23: 1645-1650.
28. Lewis TS, Shapiro PS, Ahn NG,. 1998. Signal transduction through MAP kinase cascades. Adv Cancer Res 74: 49-139.
29. Liotta LA,. 1986. Tumor invasion and metastases-role of the extracellular matrix: Rhoads Memorial Award lecture. Cancer Res 46: 1-7.
30. Manesh C, Kuttan G,. 2003. Effect of naturally occurring allyl and phenyl isothiocyanates in the inhibition of experimental pulmonary metastasis induced by B16F-10 melanoma cells. Fitoterapia 74: 355-363.
31. Mantena SK, Sharma SD, Katiyar SK,. 2006. Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. Mol Cancer Ther 5: 296-308.
32. Nyormoi O, Bar-Eli M,. 2003. Transcriptional regulation of metastasis-related genes in human melanoma. Clin Exp Metastasis 20: 251-263.
33. Obrador E, Carretero J, Ortega A, et al,. 2002. gamma-Glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver. Hepatology 35: 74-81.
34. Palmieri D, Horak CE, Lee JH, Halverson DO, Steeg PS,. 2006. Translational approaches using metastasis suppressor genes. J Bioenerg Biomembr 38: 151-161.
35. Pan MR, Chang HC, Hung WC,. 2008. Non-steroidal anti-inflammatory drugs suppress the ERK signaling pathway via block of Ras/c-Raf interaction and activation of MAP kinase phosphatases. Cell Signal 20: 1134-1141.
36. Park JH, Jeong YJ, Park KK, et al,. 2010. Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expression. Mol Cells 29: 209-215.
37. Peng PL, Hsieh YS, Wang CJ, Hsu JL, Chou FP,. 2006. Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2. Toxicol Appl Pharmacol 214: 8-15.
38. Poser I, Bosserhoff AK,. 2004. Transcription factors involved in development and progression of malignant melanoma. Histol Histopathol 19: 173-188.
39. Raphael TJ, Kuttan G,. 2003. Effect of naturally occurring monoterpenes carvone, limonene and perillic acid in the inhibition of experimental lung metastasis induced by B16F-10 melanoma cells. J Exp Clin Cancer Res 22: 419-424.
40. Sakai M, Kato H, Sano A, et al,. 2009. Expression of lysyl oxidase is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma. Ann Surg Oncol 16: 2494-2501.
41. Sathyavathi GV, Gupta AK, Tandon N,. 1987. Medicinal plants of India. Indian Council Med Res 2: 230-239.
42. Shin M, Yan C, Boyd D,. 2002. An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression. Biochim Biophys Acta 1589: 311-316.
43. Simon C, Goepfert H, Boyd D,. 1998. Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion. Cancer Res 58: 1135-1139.
44. Skoza L, Mohos S,. 1976. Stable thiobarbituric acid chromophore with dimethyl sulphoxide. Application to sialic acid assay in analytical de-O-acetylation. Biochem J 159: 457-462.
45. Stathopoulos GT, Kollintza A, Moschos C, et al,. 2007. Tumor necrosis factor-alpha promotes malignant pleural effusion. Cancer Res 67: 9825-9834.
46. Szasz G,. 1976. Reaction-rate method for gamma-glutamyltransferase activity in serum. Clin Chem 22: 2051-2055.
47. Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y,. 2009. Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations. J Ethnopharmacol 126: 5-17.
48. Voet D, Voet JG,. 1995. Biochemistry. John Wiley and Sons: New York, 1157-1258.
49. Wang JC, Wong C, Kao WW,. 1987. Immunoreactive prolyl hydroxylase in patients with primary and secondary myelofibrosis. Br J Haematol 65: 171-174.
50. Wang S, Liu Q, Zhang Y, et al,. 2009. Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action Mol Cancer 8: 81.
51. Xie S, Price JE, Luca M, Jean D, Ronai Z, Bar-Eli M,. 1997. Dominant-negative CREB inhibits tumor growth and metastasis of human melanoma cells. Oncogene 15: 2069-2075.
52. Yang J, Richmond A,. 2001. Constitutive IkappaB kinase activity correlates with nuclear factor-kappaB activation in human melanoma cells. Cancer Res 61: 4901-4909.
53. Yang XC, Tu CX, Luo PH, et al,. 2010. Antimetastatic activity of MONCPT in preclinical melanoma mice model. Invest New Drugs 28: 800-811.