-
2
-
-
0001929068
-
Progress in the chemistry of organic natural products
-
Herz W, Kirby GW, Steglich W, Tamm C, editors. Springer-Verlag; New York
-
Murray RDH. Progress in the chemistry of organic natural products. In: Herz W, Kirby GW, Steglich W, Tamm C, editors. Coumarins. Volume 58 Springer-Verlag; New York: 1991. p. 84-316
-
(1991)
Coumarins
, vol.58
, pp. 84-316
-
-
Murray, R.D.H.1
-
3
-
-
15944389028
-
Simple coumarins and analogues in medicinal chemistry: Occurrence, synthesis and biological activity
-
DOI 10.2174/0929867053507315
-
Borges F, Roleira F, Milhazes N, et al. Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity. Curr Med Chem 2005;12:887-916 (Pubitemid 40443846)
-
(2005)
Current Medicinal Chemistry
, vol.12
, Issue.8
, pp. 887-916
-
-
Borges, F.1
Roleira, F.2
Milhazes, N.3
Santana, L.4
Uriarte, E.5
-
4
-
-
6944222563
-
Natural and synthetic coumarin derivatives with anti-inflammatory/ antioxidant activities
-
DOI 10.2174/1381612043382710
-
Fylaktakidou KC, Hadjipavlou-Litina D, Litinas KE, Nicolaides DN. Natural and synthetic coumarin derivatives with antiinflammatory/antioxidant Activities. Curr Pharm Des 2004;10:3813-33 The antioxidant and anti-inflammatory properties of natural and synthetic coumarins are given and the structural requirements correlated with these activities are discussed. (Pubitemid 39409872)
-
(2004)
Current Pharmaceutical Design
, vol.10
, Issue.30
, pp. 3813-3833
-
-
Fylaktakidou, K.C.1
Hadjipavlou-Litina, D.J.2
Litinas, K.E.3
Nicolaides, D.N.4
-
5
-
-
84859573170
-
Application of coumarin compounds in preparing medicine for inducing directional differentiation of neural stem cell
-
inventors, The Second Military Medical University, The Chinese People's Liberation Army, Peop. Rep. China, assignee. WO040153
-
He C, Zhang W, Xu X, et al. inventors, The Second Military Medical University, The Chinese People's Liberation Army, Peop. Rep. China, assignee. Application of coumarin compounds in preparing medicine for inducing directional differentiation of neural stem cell. WO040153; 2008
-
(2008)
-
-
He, C.1
Zhang, W.2
Xu, X.3
-
6
-
-
17944382226
-
Advances in biological activities of coumarins
-
Zhang SY, Meng L, Gao WY, et al. Advances in biological activities of coumarins. Chin J Chin Mater Med 2005;30:410-14
-
(2005)
Chin J Chin Mater Med
, vol.30
, pp. 410-414
-
-
Zhang, S.Y.1
Meng, L.2
Gao, W.Y.3
-
7
-
-
77955810857
-
Coumarin compound and use thereof
-
inventors, Sumitomo Chemical Co. Ltd Japan, assignee. WO031706
-
Kubo H, Nagahori H, Tomigahara Y, et al. inventors, Sumitomo Chemical Co. Ltd Japan, assignee. Coumarin compound and use thereof. WO031706; 2009
-
(2009)
-
-
Kubo, H.1
Nagahori, H.2
Tomigahara, Y.3
-
8
-
-
0029593494
-
Characteristics of human types 1, 2 and 3 17beta-hydroxysteroid dehydrogenase activities: Oxidation/reduction and inhibition
-
DOI 10.1016/0960-0760(95)00209-X
-
Luu-The V, Zhang Y, Poirier D, Labrie F. Characteristics of human types 1, 2 and 3 17beta-hydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition. J Steroid Biochem Mol Biol 1995;55:581-7 (Pubitemid 26019342)
-
(1995)
Journal of Steroid Biochemistry and Molecular Biology
, vol.55
, Issue.5-6
, pp. 581-587
-
-
Luu-The, V.1
Zhang, Y.2
Poirier, D.3
Labrie, F.4
-
9
-
-
0035019952
-
Inhibitors of steroidogenesis as agents for the treatment of hormone-dependent cancers
-
This publication presents an extended study on 17β-HSD inhibitors
-
Smith HJ, Nicholls PJ, Simons C, Le Lain R. Inhibitors of steroidogenesis as agents for the treatment of hormone-dependent cancers. Exp Opin Ther Patents 2001;11:789-824 This publication presents an extended study on 17β-HSD inhibitors.
-
(2001)
Exp Opin Ther Patents
, vol.11
, pp. 789-824
-
-
Smith, H.J.1
Nicholls, P.J.2
Simons, C.3
Le Lain, R.4
-
10
-
-
0036023109
-
Some coumarins and triphenylethene derivatives as inhibitors of human testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD type 3): Further studies with tamoxifen on the rat testes microsomal enzyme
-
DOI 10.1080/14756360290026441
-
Le Lain R, Barrell KJ, Saeed GS, et al. Some coumarins and triphenylethene derivatives as inhibitors of human testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD type 3): further studies with tamoxifen on the rat testes microsomal enzyme. J Enzyme Inhib Med Chem 2002;17:93-100 (Pubitemid 34855326)
-
(2002)
Journal of Enzyme Inhibition and Medicinal Chemistry
, vol.17
, Issue.2
, pp. 93-100
-
-
Le, L.R.1
Barrell, K.J.2
Saeed, G.S.3
Nicholls, P.J.4
Simons, C.5
Kirby, A.6
Smith, H.J.7
-
11
-
-
84981375683
-
Constituents of kawa root XIV. Cinnamoylacetic esters
-
Borsche W, Lewinsohn M. Constituents of kawa root XIV. Cinnamoylacetic esters. Berichte 1933;66B:1792-801
-
(1933)
Berichte
, vol.66 B
, pp. 1792-1801
-
-
Borsche, W.1
Lewinsohn, M.2
-
12
-
-
33749267261
-
Flavonoids and cinnamic acid esters as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase: A synthesis, QSAR and modelling study
-
DOI 10.1016/j.bmc.2006.07.027, PII S0968089606005815
-
Sova M, Perdih A, Kotnik M, et al. Flavonoids and cinnamic acid esters as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase: a synthesis, QSAR and modelling study. Bioorg Med Chem 2006;14:7404-18 (Pubitemid 44486808)
-
(2006)
Bioorganic and Medicinal Chemistry
, vol.14
, Issue.22
, pp. 7404-7418
-
-
Sova, M.1
Perdih, A.2
Kotnik, M.3
Kristan, K.4
Rizner, T.L.5
Solmajer, T.6
Gobec, S.7
-
13
-
-
77955810857
-
Coumarin compound and use thereof
-
inventors, Sumitomo Chemical Co., Ltd., Japan, assignee. WO031709
-
Kubo H, Nagahori H, Tomigahara Y, et al. inventors, Sumitomo Chemical Co., Ltd., Japan, assignee. Coumarin compound and use thereof. WO031709; 2009
-
(2009)
-
-
Kubo, H.1
Nagahori, H.2
Tomigahara, Y.3
-
14
-
-
84859622411
-
Coumarin compounds for the treatment of cardiovascular diseases and process for preparing the same
-
inventors, Delhi University, India and Vallabhbhai Patel Chest Institute, assignees. WO157020
-
Parmar VS, Raj HG, Prasad AK, Jain SC. inventors, Delhi University, India and Vallabhbhai Patel Chest Institute, assignees. Coumarin compounds for the treatment of cardiovascular diseases and process for preparing the same. WO157020; 2009
-
(2009)
-
-
Parmar, V.S.1
Raj, H.G.2
Prasad, A.K.3
Jain, S.C.4
-
15
-
-
84879330203
-
Coumarin compounds as receptors modulators with therapeutic utility
-
inventors, Allergan, Inc. USA, assignee. WO050054
-
Heidelbaugh TM, Cappiello JR, Nguyen P, Gomez DG. inventors, Allergan, Inc. USA, assignee. Coumarin compounds as receptors modulators with therapeutic utility. WO050054; 2011
-
(2011)
-
-
Heidelbaugh, T.M.1
Cappiello, J.R.2
Nguyen, P.3
Gomez, D.G.4
-
16
-
-
2442534745
-
Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720
-
DOI 10.1016/j.bmcl.2004.02.106, PII S0960894X04004640
-
Hale JJ, Neway W, Mills SG, et al. Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720. Bioorg Med Chem Lett 2004;14:3351-5 (Pubitemid 38624622)
-
(2004)
Bioorganic and Medicinal Chemistry Letters
, vol.14
, Issue.12
, pp. 3351-3355
-
-
Hale, J.J.1
Neway, W.2
Mills, S.G.3
Hajdu, R.4
Ann, K.C.5
Rosenbach, M.6
Milligan, J.7
Shei, G.-J.8
Chrebet, G.9
Bergstrom, J.10
Card, D.11
Koo, G.C.12
Koprak, S.L.13
Jackson, J.J.14
Rosen, H.15
Mandala, S.16
-
17
-
-
84859616392
-
Novobiocin analogues and treatment of polycystic kidney disease
-
inventors, University of Kansas, USA, assignees. US0082098
-
Calvet JP, Blagg BSJ, Sundar SV, Magenheimer BS. inventors, University of Kansas, USA, assignees. Novobiocin analogues and treatment of polycystic kidney disease. US0082098; 2011
-
(2011)
-
-
Calvet, J.P.1
Blagg, B.S.J.2
Sundar, S.V.3
Magenheimer, B.S.4
-
18
-
-
5444253305
-
Synthesis of (-)-noviose from 2,3-O-isopropylidene-D-erythronolactol
-
DOI 10.1021/jo048953t
-
Yu XM, Shen G, Blagg BSJ. Synthesis of (-)-Noviose from 2,3-O-Isopropylidene-D-erythronolactol. J Org Chem 2004;69:7375-8 (Pubitemid 39363045)
-
(2004)
Journal of Organic Chemistry
, vol.69
, Issue.21
, pp. 7375-7378
-
-
Yu, X.M.1
Shen, G.2
Blagg, B.S.J.3
-
19
-
-
0037971925
-
Novel coumarin derivatives of heterocyclic compounds as lipid-lowering agents
-
DOI 10.1016/S0960-894X(03)00490-6
-
Madhavan GR, Balraju V, Mallesham B, et al. Novel coumarin derivatives of heterocyclic compounds as lipid-lowering agents. Bioorg Med Chem Lett 2003;13:2547-51 (Pubitemid 36830770)
-
(2003)
Bioorganic and Medicinal Chemistry Letters
, vol.13
, Issue.15
, pp. 2547-2551
-
-
Madhavan, G.R.1
Balraju, V.2
Mallesham, B.3
Chakrabarti, R.4
Lohray, V.B.5
-
21
-
-
25144435448
-
Hsp90 inhibitors identified from a library of novobiocin analogues
-
DOI 10.1021/ja0535864
-
Yu XM, Shen G, Neckers L, et al. Hsp90 inhibitors identified from a library of novobiocin analogues. J Am Chem Soc 2005;127:12778-9 (Pubitemid 41339147)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.37
, pp. 12778-12779
-
-
Yu, X.M.1
Shen, G.2
Neckers, L.3
Blake, H.4
Holzbeierlein, J.5
Cronk, B.6
Blagg, B.S.J.7
-
22
-
-
33645456243
-
Calcium restores a normal proliferation phenotype in human polycystic kidney disease epithelial cells
-
Yamaguchi T, Hempson SJ, Reif GA, et al. Calcium restores a normal proliferation phenotype in human polycystic kidney disease epithelial cells. J Am Soc Nephrol 2006;17:178-87
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 178-187
-
-
Yamaguchi, T.1
Hempson, S.J.2
Reif, G.A.3
-
23
-
-
84859602183
-
Pharmaceutical composition useful as acetylcholinesterase inhibitors
-
inventors, Council of Scientific and Industrial Research New Delhi, India, assignee. US0009544
-
Rao JM, Bhimapaka CR, Pullela VS, et al. inventors, Council of Scientific and Industrial Research New Delhi, India, assignee. Pharmaceutical composition useful as acetylcholinesterase inhibitors. US0009544; 2008
-
(2008)
-
-
Rao, J.M.1
Bhimapaka, C.R.2
Pullela, V.S.3
-
24
-
-
12444257779
-
3-(4-{[benzyl(methyl)amino]methyl}-phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: A dual function lead for Alzheimer's disease therapy
-
DOI 10.1021/jm0340602
-
Piazzi L, Rampa A, Bisi A, et al. 3-(4-{[Benzyl(methyl)amino]methyl} phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both Acetylcholinesterase and Acetylcholinesterase-induced beta-Amyloid aggregation: a dual function lead for Alzheimer's disease therapy. J Med Chem 2003;46:2279-82 (Pubitemid 36637912)
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, Issue.12
, pp. 2279-2282
-
-
Piazzi, L.1
Rampa, A.2
Bisi, A.3
Gobbi, S.4
Belluti, F.5
Cavalli, A.6
Bartolini, M.7
Andrisano, V.8
Valenti, P.9
Recanatini, M.10
-
26
-
-
84859606863
-
Compounds, compositions and methods for preventing skin darkening
-
inventors, New York University, USA, assignee. US0190229
-
Orlow SJ, Komatsu LN. inventors, New York University, USA, assignee. Compounds, compositions and methods for preventing skin darkening. US0190229; 2011
-
(2011)
-
-
Orlow, S.J.1
Komatsu, L.N.2
-
27
-
-
0002146569
-
The biogenesis of melanosomes
-
Nordlund JJ, Boissy RE, Hearing VJ, et al. editors. Oxford University Press; New York: A detailed presentation on the role and the physiology of the pigmentary system is given
-
Orlow SJ. The biogenesis of melanosomes. In: The pigmentary system: Physiology and Pathophysiology. Nordlund JJ, Boissy RE, Hearing VJ, et al. editors. Oxford University Press; New York: 1998 A detailed presentation on the role and the physiology of the pigmentary system is given.
-
(1998)
The Pigmentary System: Physiology and Pathophysiology
-
-
Orlow, S.J.1
-
28
-
-
84859616394
-
Tetriacyclodipyranyl coumarins and the anti-HIV and antituberculosis uses thereof
-
inventors, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peop. Rep. China, assignee. EP2216335
-
Liu G, Xue H, Ma T, et al. inventors, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peop. Rep. China, assignee. Tetriacyclodipyranyl coumarins and the anti-HIV and antituberculosis uses thereof. EP2216335; 2010
-
(2010)
-
-
Liu, G.1
Xue, H.2
Ma, T.3
-
29
-
-
0037404483
-
Recent progress in the development of coumarin derivatives as potent anti-HIV agents
-
The review is presenting coumarins as promising molecular scaffolds for the development of HIV chemotherapeutic agents
-
Donglei Y, Madoka S, Lan X, et al. Recent progress in the development of coumarin derivatives as potent anti-HIV agents. Med Res Rev 2003;23:322-45 The review is presenting coumarins as promising molecular scaffolds for the development of HIV chemotherapeutic agents.
-
(2003)
Med Res Rev
, vol.23
, pp. 322-345
-
-
Donglei, Y.1
Madoka, S.2
Lan, X.3
-
30
-
-
0026647540
-
The Calanolides, a Novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, calophyllum lanigerum
-
Calanolide A the most active compound against HIV-1 replication
-
Kashman Y, Gustafson KR, Fuller RW, et al. The Calanolides, a Novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, calophyllum lanigerum. J Med Chem 1992;35:2735-43 Calanolide A the most active compound against HIV-1 replication.
-
(1992)
J Med Chem
, vol.35
, pp. 2735-2743
-
-
Kashman, Y.1
Gustafson, K.R.2
Fuller, R.W.3
-
31
-
-
77249123906
-
Highly Suppressing Wild-Type HIV-1 and Y181C Mutant HIV-1 Strains by 10-Chloromethyl-11-demethyl-12-oxocalanolide A with druggable profile
-
Xue H, Lu X, Zheng P, et al. Highly Suppressing Wild-Type HIV-1 and Y181C Mutant HIV-1 Strains by 10-Chloromethyl-11-demethyl-12-oxocalanolide A with druggable profile. J Med Chem 2010;53:1397-401
-
(2010)
J Med Chem
, vol.53
, pp. 1397-1401
-
-
Xue, H.1
Lu, X.2
Zheng, P.3
-
32
-
-
41749084640
-
Chemical library and structure-activity relationships of 11-demethyl-12-oxo calanolide A analogues as anti-HIV-1 agents
-
DOI 10.1021/jm701405p
-
Ma T, Liu L, Xue H, et al. Chemical library and structure-activity relationships of 11-Demethyl-12-oxo Calanolide A analogues as Anti-HIV-1 Agents. J Med Chem 2008;51:1432-46 (Pubitemid 351484798)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.5
, pp. 1432-1446
-
-
Ma, T.1
Liu, L.2
Xue, H.3
Li, L.4
Han, C.5
Wang, L.6
Chen, Z.7
Liu, G.8
-
33
-
-
0029956809
-
Structure-activity modifications of the HIV-1 inhibitors (+)-calanolide A and (-)-calanolide B
-
DOI 10.1021/jm9602827
-
Galinis DL, Fuller RW, McKee TC, et al. Structure-Activity Modifications of the HIV-1 Inhibitors (+)-Calanolide A and (-)-Calanolide B1. J Med Chem 1996;39:4507-10 (Pubitemid 26359408)
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, Issue.22
, pp. 4507-4510
-
-
Galinis, D.L.1
Fuller, R.W.2
McKee, T.C.3
Cardellina II, J.H.4
Gulakowski, R.J.5
McMahon, J.B.6
Boyd, M.R.7
-
34
-
-
13344277278
-
Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (±)-calanolide A and its enantiomers
-
DOI 10.1021/jm950797i
-
Flavin MT, Rizzo JD, Khilevich A, et al. Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (±)-Calanolide A and its enantiomers. J Med Chem 1996;39:1303-13 (Pubitemid 26089845)
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, Issue.6
, pp. 1303-1313
-
-
Flavin, M.T.1
Rizzo, J.D.2
Khilevich, A.3
Kucherenko, A.4
Sheinkman, A.K.5
Vilaychack, V.6
Lin, L.7
Chen, W.8
Greenwood, E.M.9
Pengsuparp, T.10
Pezzuto, J.M.11
Hughes, S.H.12
Flavin, T.M.13
Cibulski, M.14
Boulanger, W.A.15
Shone, R.L.16
Xu, Z.-Q.17
-
35
-
-
1342300734
-
Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis
-
DOI 10.1016/j.bmc.2003.11.012
-
Xu ZQ, Barrow WW, Suling WJ, et al. Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis. Bioorg Med Chem 2004;12:1199-207 (Pubitemid 38251310)
-
(2004)
Bioorganic and Medicinal Chemistry
, vol.12
, Issue.5
, pp. 1199-1207
-
-
Xu, Z.-Q.1
Barrow, W.W.2
Suling, W.J.3
Westbrook, L.4
Barrow, E.5
Lin, Y.-M.6
Flavin, M.T.7
-
36
-
-
0030892146
-
Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry
-
Chen ZW, Zhou P, Ho DD, et al. Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry. J Virol 1997;4:2705-14 (Pubitemid 27119907)
-
(1997)
Journal of Virology
, vol.71
, Issue.4
, pp. 2705-2714
-
-
Chen, Z.1
Zhou, P.2
Ho, D.D.3
Landau, N.R.4
Marx, P.A.5
-
37
-
-
84859563761
-
Antimicrobial agents that target bacterial vitamin K epoxide reductase
-
inventors, President and Fellows of Harvard College, USA, assignee. WO045381
-
Beckwith J, Dutton R, Boyd D, Berkmen M. inventors, President and Fellows of Harvard College, USA, assignee. Antimicrobial agents that target bacterial vitamin K epoxide reductase. WO045381; 2010
-
(2010)
-
-
Beckwith, J.1
Dutton, R.2
Boyd, D.3
Berkmen, M.4
-
38
-
-
76249133943
-
Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin
-
Dutton RJ, Wayman A, Wei JR, et al. Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin. Proc Natl Acad Sci 2010;107:297-301
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 297-301
-
-
Dutton, R.J.1
Wayman, A.2
Wei, J.R.3
-
39
-
-
3242786500
-
Vitamin K epoxide reductase: Homology, active site and catalytic mechanism
-
DOI 10.1016/j.tibs.2004.04.004, PII S0968000404000829
-
Goodstadt L, Ponting CP. Vitamin K epoxide reductase: homology, active site and catalytic mechanism. Trends Biochem Sci 2004;29:289-92 (Pubitemid 38968759)
-
(2004)
Trends in Biochemical Sciences
, vol.29
, Issue.6
, pp. 289-292
-
-
Goodstadt, L.1
Ponting, C.P.2
-
40
-
-
77953323133
-
Synthesis, anticoagulant and PIVKA-II induced by new 4-hydroxycoumarin derivatives
-
Abdelhafez OM, Amin KM, Batran RZ, et al. Synthesis, anticoagulant and PIVKA-II induced by new 4-hydroxycoumarin derivatives. Bioorg Med Chem 2010;18:3371-8
-
(2010)
Bioorg Med Chem
, vol.18
, pp. 3371-3378
-
-
Abdelhafez, O.M.1
Amin, K.M.2
Batran, R.Z.3
-
41
-
-
11844288965
-
Antimycobacterial coumarins from the Sardinian giant fennel (Ferula communis)
-
DOI 10.1021/np049706n
-
Appendino G, Mercalli E, Fuzzati N, et al. Antimycobacterial Coumarins from the Sardinian Giant Fennel (Ferula communis). J Nat Prod 2004;67:2108-10 (Pubitemid 40092568)
-
(2004)
Journal of Natural Products
, vol.67
, Issue.12
, pp. 2108-2110
-
-
Appendino, G.1
Mercalli, E.2
Fuzzati, N.3
Arnoldi, L.4
Stavri, M.5
Gibbons, S.6
Ballero, M.7
Maxia, A.8
-
42
-
-
34548582172
-
Characterization of anti-coagulant properties of prenylated coumarin ferulenol
-
Monti M, Pinotti M, Appendino G, et al. Characterization of anti-coagulant properties of prenylated coumarin ferulenol. Biochim Biophys Acta 2007;1770:1437-40
-
(2007)
Biochim Biophys Acta
, vol.1770
, pp. 1437-1440
-
-
Monti, M.1
Pinotti, M.2
Appendino, G.3
-
43
-
-
4644371794
-
Current options in the prevention of thromboembolic disease
-
Ansell J, Bargqvist D. Current options in the prevention of thromboembolic disease. Drugs 2004;64:1-5 (Pubitemid 39280364)
-
(2004)
Drugs
, vol.64
, Issue.SUPPL. 1
, pp. 1-5
-
-
Ansell, J.1
Bergqvist, D.2
-
44
-
-
33749426542
-
Recent advances in coumarins and 1-azacoumarins as versatile biodynamic agents
-
DOI 10.2174/092986706778521968
-
Kulkarni MV, Kulkarni GM, Lin CH, Sun CM. Recent advances in coumarins and 1-azacoumarins as versatile biodynamic agents. Curr Med Chem 2006;13:2795-818 The authors describe coumarin derivatives with chemical modifications at different positions of the core structure that present antitumor activity. (Pubitemid 44509726)
-
(2006)
Current Medicinal Chemistry
, vol.13
, Issue.23
, pp. 2795-2818
-
-
Kulkarni, M.V.1
Kulkarni, G.M.2
Lin, C.-H.3
Sun, C.-M.4
-
45
-
-
84859607123
-
Novel coumarin derivatives having antitumor activity
-
inventors, Chugai Seiyaku Kabushiki Kaisha, Japan, assignee. EP1982982
-
Iikura H, Hyoudoh I, Aoki T, et al. inventors, Chugai Seiyaku Kabushiki Kaisha, Japan, assignee. Novel coumarin derivatives having antitumor activity. EP1982982; 2008
-
(2008)
-
-
Iikura, H.1
Hyoudoh, I.2
Aoki, T.3
-
46
-
-
84859589926
-
NFAT Signal Inhibitor and Hair growing agent
-
inventors, Kao Corp. Chuo-ku Tokyo, Japan, assignee. EP2348025A1
-
Sakasai M, Shibuya Y, Nagasawa A. inventors, Kao Corp. Chuo-ku Tokyo, Japan, assignee. NFAT Signal Inhibitor and Hair growing agent. EP2348025A1; 2011
-
(2011)
-
-
Sakasai, M.1
Shibuya, Y.2
Nagasawa, A.3
-
47
-
-
79953783039
-
Coumarin Compounds and their use for treating cancer
-
inventors, National Health Research Institutes, Taiwan, assignee. US0312317
-
Hsieh H-P, Chang J-Y, Kuo C-C, Chao Y-S. inventors, National Health Research Institutes, Taiwan, assignee. Coumarin Compounds and their use for treating cancer. US0312317; 2009
-
(2009)
-
-
Hsieh, H.-P.1
Chang, J.-Y.2
Kuo, C.-C.3
Chao, Y.-S.4
-
48
-
-
3042740981
-
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo
-
Kuo CC, Hsieh HP, Pan WY, et al. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo. Cancer Res 2004;64:4621-8
-
(2004)
Cancer Res
, vol.64
, pp. 4621-4628
-
-
Kuo, C.C.1
Hsieh, H.P.2
Pan, W.Y.3
-
49
-
-
0030039669
-
Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol
-
DOI 10.1021/bi9515127
-
ter Haar E, Kowalski RJ, Hamel E, et al. Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol. Biochemistry 1996;9:243-50 (Pubitemid 26037301)
-
(1996)
Biochemistry
, vol.35
, Issue.1
, pp. 243-250
-
-
Ter, H.E.1
Kowalski, R.J.2
Hamel, E.3
Lin, C.M.4
Longley, R.E.5
Gunasekera, S.P.6
Rosenkranz, H.S.7
Day, B.W.8
-
50
-
-
85022217670
-
Discodermolide analogues and methods of their use
-
inventors, The Trustees of the University of Pennsylvania & Kosan Biosciences, Inc., assignees. WO006184
-
Smith AB, Shaw SJ, Myles DC. inventors, The Trustees of the University of Pennsylvania & Kosan Biosciences, Inc., assignees. Discodermolide analogues and methods of their use. WO006184; 2009
-
(2009)
-
-
Smith, A.B.1
Shaw, S.J.2
Myles, D.C.3
-
51
-
-
84859589927
-
Coumarin derivatives, preparation processes and used there of
-
inventor, Nanjing Zhongrui Pharmaceutical Co., Ltd., Peop. Rep. China, assignee. WO036656
-
Su G. inventor, Nanjing Zhongrui Pharmaceutical Co., Ltd., Peop. Rep. China, assignee. Coumarin derivatives, preparation processes and used there of. WO036656; 2009
-
(2009)
-
-
Su, G.1
-
52
-
-
9744254492
-
Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT
-
DOI 10.1055/s-2004-832640
-
Marquez N, Sancho R, Ballero M, et al. Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT. Planta Medica 2004;70:1016-21 (Pubitemid 39587033)
-
(2004)
Planta Medica
, vol.70
, Issue.11
, pp. 1016-1021
-
-
Marquez, N.1
Sancho, R.2
Ballero, M.3
Bremner, P.4
Appendino, G.5
Fiebich, B.L.6
Heinrich, M.7
Munoz, E.8
-
53
-
-
84859589926
-
NFAT signal inhibitor and Hair-growing agent
-
Kao Corp., Tokyo, Japan, WO2010047103A1
-
Sakasai M, Shibuya Y, Nagasawa A. Kao Corp., Tokyo, Japan, NFAT signal inhibitor and Hair-growing agent. WO2010047103A1 2010
-
(2010)
-
-
Sakasai, M.1
Shibuya, Y.2
Nagasawa, A.3
-
54
-
-
0021741922
-
Studies on coumarins of a Chinese drug 'Qian-Hu'; VI. Coumarins of Angelica edulis
-
DOI 10.1055/s-2007-969781
-
Kawasaki C, Okuyama T, Shibata S, Iitaka Y. Studies on coumarins of a Chinese drug "Qian Hu"; VI. Coumarins of Angelica edulis. Planta Medica 1984;50:492-6 (Pubitemid 15180172)
-
(1984)
Planta Medica
, vol.50
, Issue.6
, pp. 492-496
-
-
Kawasaki, C.1
Okuyama, T.2
Iitaka, Y.3
Shibata, S.4
-
55
-
-
84859623175
-
Novel Coumarin-based compounds, preparation method thereof and multidrug resistance inhibitory pharmaceutical compositions containing same as active ingredients
-
inventors, Korea Research Institute of Bioscience and Biotechnology, assignee. WO064817
-
Lee K, Min JH, Lee K, et al. inventors, Korea Research Institute of Bioscience and Biotechnology, assignee. Novel Coumarin-based compounds, preparation method thereof and multidrug resistance inhibitory pharmaceutical compositions containing same as active ingredients. WO064817; 2010
-
(2010)
-
-
Lee, K.1
Min, J.H.2
Lee, K.3
-
56
-
-
0032211830
-
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
-
Selkoe DJ. The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol 1998;8:447-53
-
(1998)
Trends Cell Biol
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
57
-
-
0034681260
-
Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
-
Brown MS, Ye J, Rawson RB, Goldstein JL. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 2000;18:391-8
-
(2000)
Cell
, vol.18
, pp. 391-398
-
-
Brown, M.S.1
Ye, J.2
Rawson, R.B.3
Goldstein, J.L.4
-
58
-
-
84859569137
-
Coumarin-based compounds
-
inventors, Sloan-Kettering Institute for Cancer Research, New York, USA, assignee. WO075280
-
Zhu L, Djaballah H, Li Y, Shelton CC. inventors, Sloan-Kettering Institute for Cancer Research, New York, USA, assignee. Coumarin-based compounds. WO075280; 2010
-
(2010)
-
-
Zhu, L.1
Djaballah, H.2
Li, Y.3
Shelton, C.C.4
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