Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT

Planta Medica

Volumn 70, Issue 11, 2004, Pages 1016-1021

  Márquez, Nieves ^a   Sancho, Rocío ^a   Ballero, Mauro ^c   Bremner, Paul ^d   Appendino, Giovanni ^b   Fiebich, Bernd L ^e   Heinrich, Michael ^d   Muñoz, Eduardo ^a  

^a Facultad de Medicina de Córdoba   (Spain)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^c Dipartimento di Scienze Botaniche   (Italy)

^d UNIVERSITY OF LONDON   (United Kingdom)

^e UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Apiaceae; Furanocoumarins; Imperatorin; NFAT; Oppopanax chironium; T cells

Indexed keywords

BERGAPTEN; FUROCOUMARIN DERIVATIVE; HERACLENIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; METHOXSALEN; PENTOSALEN; PEUCEDANIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA BINDING; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOMODULATION; LEUKEMIA CELL LINE; LYMPHOCYTE PROLIFERATION; OPPOPANAX CHIRONIUM; PLANT; PLANT ROOT; PLASMID; PROMOTER REGION; T LYMPHOCYTE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APIACEAE; CELL PROLIFERATION; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; JURKAT CELLS; LEUKOCYTES, MONONUCLEAR; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; PSORALENS; T-LYMPHOCYTES; TRANSCRIPTION FACTORS;

APIACEAE;

EID: 9744254492     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-832640     Document Type: Article

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