-
1
-
-
0043160737
-
Oral insulin: Pharmacokinetics and pharmacodynamics of human insulin following oral administration of an insulin/ delivery agent capsule in healthy volunteers
-
Abbas R, Leone-Bay A, Agawal RK, Majuru S, Rolan P, Clarke C, Scott C, Arbit E, Baughman RA. Oral insulin: Pharmacokinetics and pharmacodynamics of human insulin following oral administration of an insulin/ delivery agent capsule in healthy volunteers. Diabetes, 2002;51:197.
-
(2002)
Diabetes
, vol.51
, pp. 197
-
-
Abbas, R.1
Leone-Bay, A.2
Agawal, R.K.3
Majuru, S.4
Rolan, P.5
Clarke, C.6
Scott, C.7
Arbit, E.8
Baughman, R.A.9
-
2
-
-
0030271514
-
Studies on diffusion in alginate gels. I. Effect of cross-linking with calcium or zinc ions on diffusion of acetaminophen
-
DOI 10.1016/0168-3659(96)01369-7
-
Aslani P, Kennedy RA. Studies on diffusion in alginate gels. 1. Effect of cross-linking with calcium or zinc ions on diffusion of acetaminophen. J Controlled Release, 1996;42:75-82. (Pubitemid 26297878)
-
(1996)
Journal of Controlled Release
, vol.42
, Issue.1
, pp. 75-82
-
-
Aslani, P.1
Kennedy, R.A.2
-
3
-
-
0033816196
-
Intestinal permeation enhancers
-
Aungst BJ. Intestinal permeation enhancers. J Pharm Sci, 2000;89:429-42.
-
(2000)
J Pharm Sci
, vol.89
, pp. 429-442
-
-
Aungst, B.J.1
-
4
-
-
44249095621
-
Developments in polymeric devices for oral insulin delivery
-
DOI 10.1517/17425247.5.4.403
-
Babu VR, Patel P, Mundargi RC, Rangaswamy V, Aminabhavi TM. Developments in polymeric devices for oral insulin delivery. Exp Opin Drug Delivery, 2008;5:403-15. (Pubitemid 351721720)
-
(2008)
Expert Opinion on Drug Delivery
, vol.5
, Issue.4
, pp. 403-415
-
-
Babu, V.R.1
Patel, P.2
Mundargi, R.C.3
Rangaswamy, V.4
Aminabhavi, T.M.5
-
5
-
-
84859579050
-
Device and method for preparing microparticles. PCT WO 2009062254-A1, World Intellectual Property Organisation, International Bureau, USA. Builders PF, Kunle OO, Okpaku LC, Builders MO, Attama AA, Adikwu MU. Preparation and evaluation of mucinated sodium alginate microparticles for oral delivery of insulin
-
2008
-
Bhandari B. 2009. Device and method for preparing microparticles. PCT WO 2009062254-A1, World Intellectual Property Organisation, International Bureau, USA. Builders PF, Kunle OO, Okpaku LC, Builders MO, Attama AA, Adikwu MU. Preparation and evaluation of mucinated sodium alginate microparticles for oral delivery of insulin. Eur J Pharm Biopharm, 2008;70:777-83.
-
(2009)
Eur J Pharm Biopharm
, vol.70
, pp. 777-783
-
-
Bhandari, B.1
-
6
-
-
0036379293
-
Oral insulin product hexylinsulin monoconjugate 2 (HIM2) in type 1 diabetes mellitus: The glucose stabilization effects of HIM2
-
Clement S, Still JG, Kosutic G, Mcallister RG. Oral insulin product hexylinsulin monoconjugate 2 (HIM2) in type 1 diabetes mellitus: The glucose stabilization effects of HIM2. Diab Technol Ther, 2002;4:459-66.
-
(2002)
Diab Technol Ther
, vol.4
, pp. 459-466
-
-
Clement, S.1
Still, J.G.2
Kosutic, G.3
Mcallister, R.G.4
-
7
-
-
0023856501
-
New approach for oral administration of insulin with polyalkylcyanoacrylate nanocapsules as drug carrier
-
Damge C, Michel C, Aprahamian M, Couvreur P. New approach for oraladministration of insulin with polyalkylcyanoacrylate nanocapsules as drug carrier. Diabetes, 1988;37:246-51. (Pubitemid 18066612)
-
(1988)
Diabetes
, vol.37
, Issue.2
, pp. 246-251
-
-
Damge, C.1
Michel, C.2
Aprahamian, M.3
Couvreur, P.4
-
8
-
-
0037296404
-
Design of lipid nanoparticles for the oral delivery of hydrophilic macromolecules
-
DOI 10.1016/S0927-7765(02)00053-X, PII S092777650200053X
-
García-Fuentes M, Torres D, Alonso MJ. Design of lipid nanoparticles for the oral delivery of hydrophilic macromolecules. Colloids Surf B, 2003;27:159-68. (Pubitemid 36042758)
-
(2003)
Colloids and Surfaces B: Biointerfaces
, vol.27
, Issue.3
, pp. 159-168
-
-
Garcia-Fuentes, M.1
Torres, D.2
Alonso, M.J.3
-
9
-
-
78149442221
-
Diffusion loading and drug delivery characteristics of alginate gel microparticles produced by a novel impinging aerosols method
-
Hariyadi DM, Lin SC, Wang Y, Bostrom T, Turner MS, Bhandari B, Coombes AGA. Diffusion loading and drug delivery characteristics of alginate gel microparticles produced by a novel impinging aerosols method. J Drug Target, 2010;18:831-41.
-
(2010)
J Drug Target
, vol.18
, pp. 831-841
-
-
Hariyadi, D.M.1
Lin, S.C.2
Wang, Y.3
Bostrom, T.4
Turner, M.S.5
Bhandari, B.6
Coombes, A.G.A.7
-
10
-
-
0038390434
-
Control of postprandial plasma glucose by an oral insulin product (HIM2) in patients with type 2 diabetes
-
DOI 10.2337/diacare.26.2.421
-
Kipnes M, Dandona P, Tripathy D, Still JG, Kosutic G. Control of postprandial plasma glucose by an oral insulin product (HIM2) in patients with type 2 diabetes. Diab Care, 2003;26:421-6. (Pubitemid 36929066)
-
(2003)
Diabetes Care
, vol.26
, Issue.2
, pp. 421-426
-
-
Kipnes, M.1
Dandona, P.2
Tripathy, D.3
Still, J.G.4
Kosutic, G.5
-
11
-
-
0345672424
-
Oral route of peptide and protein drug delivery
-
Lee VHL. Oral route of peptide and protein drug delivery. Bio Pharm, 1992;5:39-42.
-
(1992)
Bio Pharm
, vol.5
, pp. 39-42
-
-
Lee, V.H.L.1
-
12
-
-
17344382638
-
Mucoadhesive polymers in peroral peptide drug delivery. I. Influence of mucoadhesive excipients on the proteolytic activity of intestinal enzymes
-
DOI 10.1016/0928-0987(95)00042-9
-
Lueßen HL, De Leeuw BJ, Pérard D, Lehr CM, De Boer AG, Verhoef JC, Junginger HE. Mucoadhesive polymers in peroral peptide drug delivery. I. Influence of mucoadhesive excipients on the proteolytic activity of intestinal enzymes. Eur J Pharm Sci, 1996;4:117-28. (Pubitemid 26096520)
-
(1996)
European Journal of Pharmaceutical Sciences
, vol.4
, Issue.2
, pp. 117-128
-
-
Luessen, H.L.1
De Leeuw, B.J.2
Perard, D.3
Lehr, C.-M.4
De Boer, A.G.5
Verhoef, J.C.6
Junginger, H.E.7
-
13
-
-
0021881932
-
Characterization of two epitopes on insulin using monoclonal antibodies
-
DOI 10.1016/0161-5890(85)90163-4
-
Marks A, Yip C, Wilson S. Characterization of two epitopes on insulin using monoclonal antibodies. Mol. Immunol, 1985;22:285-90. (Pubitemid 15076815)
-
(1985)
Molecular Immunology
, vol.22
, Issue.3
, pp. 285-290
-
-
Marks, A.1
Yip, C.2
Wilson, S.3
-
14
-
-
34248672250
-
Insulin-loaded alginate microspheres for oral delivery - Effect of polysaccharide reinforcement on physicochemical properties and release profile
-
DOI 10.1016/j.carbpol.2007.02.012, PII S0144861707001191
-
Martins S, Sarmento B, Souto EB, Ferreira DC. Insulin-loaded alginate microspheres for oral delivery - Effect of polysaccharide reinforcement on physicochemical properties and release profile. Carbohydr Polym, 2007;69:725-31. (Pubitemid 46776851)
-
(2007)
Carbohydrate Polymers
, vol.69
, Issue.4
, pp. 725-731
-
-
Martins, S.1
Sarmento, B.2
Souto, E.B.3
Ferreira, D.C.4
-
15
-
-
0024961653
-
Alginate as immobilization material: I. Correlation between chemical and physical properties of alginate gel beads
-
DOI 10.1002/bit.260330111
-
Martinsen A, Skbjk-Braek G, Smidsrod O. Alginate as immobilization material: I. Correlation between chemical and physical properties of alginate gel beads. Biotech Bioeng, 1989;33:79-89. (Pubitemid 19010127)
-
(1989)
Biotechnology and Bioengineering
, vol.33
, Issue.1
, pp. 79-89
-
-
Martinsen, A.1
Skjak-Braek, G.2
Smidsrod, O.3
-
16
-
-
0036154274
-
Oral delivery of antigens in liposomes with some lipid compositions modulates oral tolerance to the antigens
-
Masuda K, Horie K, Suzuki R, Yoshikawa T, Hirano K. Oral delivery of antigens in liposomes with some lipid compositions modulates oral tolerance to the antigens. Microbiol Immunol, 2002;46:55-8. (Pubitemid 34101088)
-
(2002)
Microbiology and Immunology
, vol.46
, Issue.1
, pp. 55-58
-
-
Masuda, K.1
Horie, K.2
Suzuki, R.3
Yoshikawa, T.4
Hirano, K.5
-
17
-
-
31544432290
-
Novel oral insulin delivery systems based on complexation polymer hydrogels: Single and multiple administration studies in type 1 and 2 diabetic rats
-
DOI 10.1016/j.jconrel.2005.10.029, PII S0168365905005778
-
Morishita M, Goto T, Nakamura K, Lowman AM, Takayama K, Peppas NA. Novel oral insulin delivery systems based on complexation polymer hydrogels: Single and multiple administration studies in type 1 and 2 diabetic rats. J Controlled Release, 2006;110:587-94. (Pubitemid 43163448)
-
(2006)
Journal of Controlled Release
, vol.110
, Issue.3
, pp. 587-594
-
-
Morishita, M.1
Goto, T.2
Nakamura, K.3
Lowman, A.M.4
Takayama, K.5
Peppas, N.A.6
-
18
-
-
33745433818
-
Performance evaluation and cross-reactivity from insulin analogs with the ARCHITECT insulin assay
-
DOI 10.1373/clinchem.2005.065995
-
Moriyama M, Hayashi N, Ohyabu C, Mukai M, Kawano S, Kumagai S. Performance evaluation and cross-reactivity from insulin analogs with the ARCHITECT insulin assay. ClinChem, 2006;52:1423-6. (Pubitemid 43956037)
-
(2006)
Clinical Chemistry
, vol.52
, Issue.7
, pp. 1423-1426
-
-
Moriyama, M.1
Hayashi, N.2
Ohyabu, C.3
Mukai, M.4
Kawano, S.5
Kumagai, S.6
-
19
-
-
0028290373
-
Calcium-alginate beads for the oral delivery of transforming growth factor-1 (TGF-1): Stabilization of TGF-1 by the addition of polyacrylic acid within acid-treated beads
-
Mumper RJ, Hoffman AS, Puolakkainen PA, Bouchard LS, Gombotz WR. Calcium-alginate beads for the oral delivery of transforming growth factor-1 (TGF-1): Stabilization of TGF-1 by the addition of polyacrylic acid within acid-treated beads. J Controlled Release, 1994;30:241-51.
-
(1994)
J Controlled Release
, vol.30
, pp. 241-251
-
-
Mumper, R.J.1
Hoffman, A.S.2
Puolakkainen, P.A.3
Bouchard, L.S.4
Gombotz, W.R.5
-
20
-
-
0035986871
-
Encapsulation of insulin in chitosan-coated alginate beads: Oral therapeutic peptide delivery
-
DOI 10.1081/BIO-120004343
-
Onal S, Zihnioglu F. Encapsulation of insulin in chitosan-coated alginate beads: Oral therapeutic peptide delivery. Artif Cells Blood Substitutes, Immobilization Biotechnol, 2002;30:229-37. (Pubitemid 34587480)
-
(2002)
Artificial Cells, Blood Substitutes, and Immobilization Biotechnology
, vol.30
, Issue.3
, pp. 229-237
-
-
Onal, S.1
Zihnioglu, F.2
-
22
-
-
33947428315
-
Design of insulin-loaded alginate nanoparticles: Influence of the calcium ion on polymer gel matrix properties
-
Reis CP, Neufeld RJ, Riberio AJ, Viega F. Design of insulin-loaded alginate nanoparticles: Influence of the calcium ion on polymer gel matrix properties. Chem Ind Chem Eng Quart, 2007a;12:47-52.
-
(2007)
Chem Ind Chem Eng Quart
, vol.12
, pp. 47-52
-
-
Reis, C.P.1
Neufeld, R.J.2
Riberio, A.J.3
Viega, F.4
-
23
-
-
33947610989
-
Alginate microparticles as novel carrier for oral insulin delivery
-
DOI 10.1002/bit.21164
-
Reis CP, Ribeiro AJ, Neufeld RJ, Veiga F. Alginate microparticles as novel carrier for oral insulin delivery. Biotechnol Bioeng, 2007b;96:977-89. (Pubitemid 46479560)
-
(2007)
Biotechnology and Bioengineering
, vol.96
, Issue.5
, pp. 977-989
-
-
Reis, C.P.1
Ribeiro, A.J.2
Neufeld, R.J.3
Veiga, F.4
-
25
-
-
0344145387
-
Cell wall of Micrococcus lysodeikticus as the substrate of lysozyme
-
Salton MR. Cell wall of Micrococcus lysodeikticus as the substrate of lysozyme. Nature, 1952;170:746-7.
-
(1952)
Nature
, vol.170
, pp. 746-747
-
-
Salton, M.R.1
-
26
-
-
34948841373
-
Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles
-
DOI 10.1016/j.ejpb.2006.09.005, PII S0939641106002517
-
Sarmento B, Ferreira DC, Jorgensen L, Van De Weert M. Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles. Eur J Pharm Biopharm, 2007;65:10-17. (Pubitemid 44827699)
-
(2007)
European Journal of Pharmaceutics and Biopharmaceutics
, vol.65
, Issue.1
, pp. 10-17
-
-
Sarmento, B.1
Ferreira, D.C.2
Jorgensen, L.3
Van De Weert, M.4
-
27
-
-
58149166741
-
Novel composite microparticles for protein stabilization and delivery
-
Schoubben A, Blasi P, Giovagnolli S, perioli L, Rossi C, Ricci M. Novel composite microparticles for protein stabilization and delivery. Eur J Pharm Sci, 2009;36:226-34.
-
(2009)
Eur J Pharm Sci
, vol.36
, pp. 226-234
-
-
Schoubben, A.1
Blasi, P.2
Giovagnolli, S.3
Perioli, L.4
Rossi, C.5
Ricci, M.6
-
28
-
-
0037634195
-
Controlled delivery of drugs from alginate matrix
-
Shilpa A, Agrawal SS, Ray AR. Controlled delivery of drugs from alginate matrix. J Macromol Sci, 2003;C43:187-221.
-
(2003)
J Macromol Sci
, vol.C43
, pp. 187-221
-
-
Shilpa, A.1
Agrawal, S.S.2
Ray, A.R.3
-
29
-
-
33748470729
-
Insulin encapsulation in reinforced alginate microspheres prepared by internal gelation
-
DOI 10.1016/j.ejps.2006.06.008, PII S0928098706001734
-
Silva CM, Ribeiro AJ, Ferreira D, Veiga F. Insulin encapsulation in reinforced alginate microspheres prepared by internal gelation. Eur J Pharm Sci, 2006a;29:148-59. (Pubitemid 44349058)
-
(2006)
European Journal of Pharmaceutical Sciences
, vol.29
, Issue.2
, pp. 148-159
-
-
Silva, C.M.1
Ribeiro, A.J.2
Ferreira, D.3
Veiga, F.4
-
30
-
-
33644616090
-
Alginate microspheres prepared by internal gelation: Development and effect on insulin stability
-
Silva CM, Ribeiro AJ, Figueiredo IV, GonÇalves AR, Veiga F. Alginate microspheres prepared by internal gelation: Development and effect on insulin stability. Int J Pharm, 2006b;311:1-10.
-
(2006)
Int J Pharm
, vol.311
, pp. 1-10
-
-
Silva, C.M.1
Ribeiro, A.J.2
Figueiredo, I.V.3
Gonçalves, A.R.4
Veiga, F.5
-
32
-
-
0037452443
-
Hypoglycemic effect of surfactant-coated insulin solubilized in a novel solid-in-oil-in-water (S/O/W) emulsion
-
DOI 10.1016/S0378-5173(02)00674-9
-
Toorisaka E, Ono H, Arimori K, Kamiya N, Goto M. Hypoglycemic effect of surfactant-coated insulin solubilized in a novel solid-in-oil-in-water (S/O/W) emulsion. Int J Pharm, 2003;252:271-4. (Pubitemid 36126637)
-
(2003)
International Journal of Pharmaceutics
, vol.252
, Issue.1-2
, pp. 271-274
-
-
Toorisaka, E.1
Ono, H.2
Arimori, K.3
Kamiya, N.4
Goto, M.5
-
33
-
-
0037466349
-
Poly(alkylcyanoacrylates) as biodegradable materials for biomedical applications
-
DOI 10.1016/S0169-409X(03)00041-3
-
Vauthier C, Dubernet C, Fattal E, Pinto-Alphandary H, Couvreur P. Poly(alkylcyanoacrylates) as biodegradable materials for biomedical applications. Adv Drug Delivery Rev, 2003;55:519-48. (Pubitemid 36423302)
-
(2003)
Advanced Drug Delivery Reviews
, vol.55
, Issue.4
, pp. 519-548
-
-
Vauthier, C.1
Dubernet, C.2
Fattal, E.3
Pinto-Alphandary, H.4
Couvreur, P.5
-
34
-
-
78349308213
-
Calcium concentration effects on the mechanical and biochemical properties of chondrocyte-alginate constructs
-
Wan LQ, Jiang J, Arnold DE, Guo E, Lu HH, Mow VC. Calcium concentration effects on the mechanical and biochemical properties of chondrocyte-alginate constructs. Cell Mol Bioeng, 2008;1:93-102.
-
(2008)
Cell Mol Bioeng
, vol.1
, pp. 93-102
-
-
Wan, L.Q.1
Jiang, J.2
Arnold, D.E.3
Guo, E.4
Lu, H.H.5
Mow, V.C.6
-
35
-
-
33847282430
-
Extended release of high pI proteins from alginate microspheres via a novel encapsulation technique
-
Wells LA, Sheardown H. Extended release of high pI proteins from alginate microspheres via a novel encapsulation technique. Eur J Pharm Biopharm, 2007;65:329-35.
-
(2007)
Eur J Pharm Biopharm
, vol.65
, pp. 329-335
-
-
Wells, L.A.1
Sheardown, H.2
-
36
-
-
0032816086
-
Transcellular and lipophilic complex-enhanced intestinal absorption of human growth hormone
-
DOI 10.1023/A:1014809916407
-
Wu SJ, Robinson JR. Transcellular and lipophilic complex-enhanced intestinal absorption of human growth hormone. Pharm Res, 1999;16:1266-72. (Pubitemid 29393617)
-
(1999)
Pharmaceutical Research
, vol.16
, Issue.8
, pp. 1266-1272
-
-
Wu, S.-J.1
Robinson, J.R.2
-
37
-
-
0034967615
-
Preparation of regular sized Ca-alginate microspheres using membrane emulsification method
-
DOI 10.1080/02652040010018128
-
You J-O, Park S-B, Park H-Y, Haam S, Chung CH, Kim WS. Preparation of regular sized Ca-alginate microspheres using membrane emulsification method. J Microencapsulation, 2001;18:521-32. (Pubitemid 32577126)
-
(2001)
Journal of Microencapsulation
, vol.18
, Issue.4
, pp. 521-532
-
-
You, J.-O.1
Park, S.-B.2
Park, H.-Y.3
Haam, S.4
Chung, C.-H.5
Kim, W.-S.6
-
38
-
-
33846314387
-
Lysozyme-containing chitosan-coated alginate microspheres for oral immunisation
-
Zorzin L, Cocchietto M, Voinovich D, Marcuzzi A, Filipovic-Grcic J, Mulloni C, Crembiale G, Casarsa C, Bulla R, Sava G. Lysozyme-containing chitosan-coated alginate microspheres for oral immunisation. J Drug Delivery Sci Technol, 2006;16:413-20. (Pubitemid 46122248)
-
(2006)
Journal of Drug Delivery Science and Technology
, vol.16
, Issue.6
, pp. 413-420
-
-
Zorzin, L.1
Cocchietto, M.2
Voinovich, D.3
Marcuzzi, A.4
Filipovic-Grcic, J.5
Mulloni, C.6
Crembiale, G.7
Casarsa, C.8
Bulla, R.9
Sava, G.10
|