Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A

Journal of Biological Chemistry

Volumn 287, Issue 14, 2012, Pages 11422-11436

  Morcavallo, Alaide ^a,b   Genua, Marco ^a   Palummo, Angela ^b   Kletvikova, Emilia ^c   Jiracek, Jiri ^c   Brzozowski, Andrzej M ^d   Iozzo, Renato V ^a   Belfiore, Antonino ^b   Morrione, Andrea ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^c INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^d UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITIES; BIOLOGICAL RESPONSE; DEGRADATIVE PATHWAYS; DOWN-REGULATION; ENDOCYTIC SORTING; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTORS; INSULIN-LIKE GROWTH FACTOR; ISOFORMS; MITOGENIC; MITOGENS; MOUSE EMBRYONIC FIBROBLASTS; RECEPTOR ENDOCYTOSIS; SIGNALING EVENTS; UBIQUITINATION;

BINDING ENERGY; CELL CULTURE; MOLECULAR BIOLOGY; PEPTIDES; PHOSPHORYLATION; TISSUE;

INSULIN;

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR A; INSULIN RECEPTOR SUBSTRATE 1; SOMATOMEDIN B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; INTERNALIZATION; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN TRANSPORT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; BETA-CYCLODEXTRINS; CELL PROLIFERATION; CLATHRIN; DOWN-REGULATION; ENDOCYTOSIS; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-LIKE GROWTH FACTOR II; LIGANDS; MICE; NIH 3T3 CELLS; PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN TRANSPORT; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 84859510536     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.252478     Document Type: Article

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