Engineering proteins with enhanced mechanical stability by force-specific sequence motifs

Proteins: Structure, Function and Bioinformatics

Volumn 80, Issue 5, 2012, Pages 1308-1315

  Lu, Wenzhe ^a   Negi, Surendra S ^a   Oberhauser, Andres F ^a   Braun, Werner ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Atomic force microscopy; CD spectroscopy; Molecular dynamics calculations; Physical chemical property motifs; Protein design; Titin

Indexed keywords

CONNECTIN;

AMINO ACID SEQUENCE; ARTICLE; MOLECULAR CLONING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN STABILITY; SEQUENCE ANALYSIS; SIMULATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CIRCULAR DICHROISM; FIBRONECTINS; HYDROGEN BONDING; MICROSCOPY, ATOMIC FORCE; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUSCLE PROTEINS; PROTEIN ENGINEERING; PROTEIN KINASES; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 84859440380     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24027     Document Type: Article

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