Computational and single-molecule force studies of a macro domain protein reveal a key molecular determinant for mechanical stability

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 5, 2010, Pages 1989-1994

  Guzmán, Dora L ^a   Randall, Arlo ^b   Baldi, Pierre ^b   Guan, Zhibin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Ringgold Standard Institution Informatics   (United States)

Author keywords

Atomic force microscopy; Biomimetic materials; Molecular dynamics simulations; Protein engineering; Single molecule force spectroscopy

Indexed keywords

POLYPROTEIN; WATER;

ALPHA HELIX; ARTICLE; ATOMIC FORCE MICROSCOPY; BETA SHEET; BIOINFORMATICS; CONTROLLED STUDY; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STABILITY; SCREENING; SIMULATION;

ARCHAEOGLOBUS FULGIDUS; BACTERIAL PROTEINS; BIOMECHANICS; COMPUTATIONAL BIOLOGY; MICROSCOPY, ATOMIC FORCE; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEINS; THERMODYNAMICS; WATER;

EID: 76649112096     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0905796107     Document Type: Article

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