A novel mathematical model considering change of diffusion coefficient for predicting dissolution behavior of acetaminophen from wax matrix dosage form

International Journal of Pharmaceutics

Volumn 428, Issue 1-2, 2012, Pages 82-90

  Nitanai, Yuta ^a   Agata, Yasuyoshi ^a   Iwao, Yasunori ^a   Itai, Shigeru ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

AMCE; Mathematical model; Time dependent diffusivity; Wax matrix

Indexed keywords

EUDRAGIT; GLYCEROL STEARATE; PARACETAMOL; WAX;

ARTICLE; BITTER TASTE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG BIOAVAILABILITY; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; MASKING; MATHEMATICAL MODEL; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TABLET MATRIX; THEORETICAL MODEL; TIME;

ACETAMINOPHEN; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; DIFFUSION; DOSAGE FORMS; GLYCERIDES; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, CHEMICAL; PARTICLE SIZE; POLYMERS; REGRESSION ANALYSIS; SOLUBILITY; WATER; WAXES;

EID: 84859435753     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.02.036     Document Type: Article

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