Wax-based sustained release matrix pellets prepared by a novel freeze pelletization technique. II. In vitro drug release studies and release mechanisms

International Journal of Pharmaceutics

Volumn 359, Issue 1-2, 2008, Pages 167-173

  Cheboyina, Sreekhar ^a   Wyandt, Christy M ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Drug release mechanisms; Freeze pelletization; Mathematical models; Matrix pellets; Sustained release; Waxes

Indexed keywords

BRIJ 76; CETYLESTER; DILTIAZEM; GLYCEROL PALMITOSTEARATE; GLYCEROL STEARATE; HEXADECANOL; PROPOLIS; THEOPHYLLINE; WAX;

AQUEOUS SOLUTION; ARTICLE; CRYSTAL STRUCTURE; DESORPTION; DRUG DIFFUSION; DRUG MANUFACTURE; DRUG PELLET; DRUG SOLUBILITY; FREEZE PELLETIZATION; HYDROPHOBICITY; LOW TEMPERATURE PROCEDURES; PRIORITY JOURNAL; SUSTAINED RELEASE FORMULATION; SUSTAINED RELEASE PREPARATION;

CETOMACROGOL; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DELAYED-ACTION PREPARATIONS; DIFFUSION; DIGLYCERIDES; DILTIAZEM; FREEZING; GLYCERIDES; HYDROPHOBICITY; KINETICS; MICROSCOPY, ELECTRON, SCANNING; SOLUBILITY; THEOPHYLLINE; WAXES;

EID: 44749088200     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.04.001     Document Type: Article

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