Taste masking microspheres for orally disintegrating tablets

International Journal of Pharmaceutics

Volumn 359, Issue 1-2, 2008, Pages 63-69

  Xu, Jianchen ^a   Bovet, Li Li ^b   Zhao, Kang ^a  

^a TIANJIN UNIVERSITY   (China)

^b Cirrus Pharmaceuticals   (United States)

Author keywords

Microspheres; Orally disintegrating tablet; Spray drying; Taste masking

Indexed keywords

EXCIPIENT; FAMOTIDINE; MICROSPHERE;

ARTICLE; BITTER TASTE; CONCENTRATION (PARAMETERS); DRUG BIOAVAILABILITY; DRUG RELEASE; ENCAPSULATION; HUMAN; IN VIVO STUDY; MALE; MOISTURE; NONHUMAN; PRIORITY JOURNAL; RAT; SOLID; SPRAY DRYING; TABLET; VOLUNTEER;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; FAMOTIDINE; HISTAMINE H2 ANTAGONISTS; HUMANS; MALE; MICROSPHERES; PARTICLE SIZE; RATS; RATS, WISTAR; SINGLE-BLIND METHOD; SOLUBILITY; TABLETS; TASTE;

EID: 44749090403     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.03.019     Document Type: Article

References (25)

1. Abdelbary G., Prinderre P., Eouani C., Joachim J., Reynier J.P., and Piccerelle Ph. The preparation of orally disintegrating tablets using a hydrophilic waxy binder. Int. J. Pharm. 278 (2004) 423-433
2. Alysson L.R.R., and Wanderley P.O. Spray drying conditions and encapsulating composition effects on formation and properties of sodium diclofenac microparticles. Powder Technol. 171 (2007) 7-14
3. Anderson P.O., Knoben J.E., and Troutman W.G. Handbook of Clinical Drug Data. 10th ed. (2002), McGraw-Hill, USA
4. Bruschia M.L., Cardosoa M.L.C., Lucchesib M.B., and Gremião M.P.D. Gelatin microparticles containing propolis obtained by spray-drying technique: preparation and characterisation. Int. J. Pharm. 264 (2003) 45-55
5. Gao Y., Cui F.D., Guan Y., Yang L., Wang Y.Sh., and Zhang L.N. Preparation of roxithromycin-polymeric microspheres by the emulsion solvent diffusion method for taste masking. Int. J. Pharm. 318 (2006) 62-69
6. Giunchedi P., Conti B., Genta I., Conte U., and Puglisi G. Emulsion spray drying for the preparation of albumin-loaded PLGA microspheres. Drug Dev. Ind. Pharm. 27 (2001) 745-750
7. Hashimoto Y., Tanaka M., and Kishimoto H. Preparation, characterisation and taste-masking properties of polyvinylacetal diethylaminoacetate microspheres containing trimebutine. J. Pharm. Pharmacol. 54 (2002) 1323
8. Hiroyuki S., Hiraku O., Yuri T., Masanori I., and Yoshiharu M. Development of oral acetaminophen chewable tablets with inhibited bitter taste. Int. J. Pharm. 251 (2003) 123-132
9. Ishikawa T., Watanabe Y., Utoguchi N., and Matsumoto M. Preparation and evaluation of tablets rapidly disintegrating in saliva containing bitter-taste-masked granules by the compression method. Chem. Pharm. Bull. 47 (1999) 1451-1454
10. Kajiyama, A., Tamura, T., Mizumoto, T., Kawai, H., Takahashi, T., December 2, 2003. Quick disintegrating tablet in buccal cavity and manufacturing method thereof. US Patent 6,656,492.
11. Kayumba P.C., Huyghebaert N., Cordella C., Ntawukuliryayo J.D., Vervaet C., and Remon J.P. Quinine sulphate pellets for flexible pediatric drug dosing: formulation development and evaluation of taste masking efficiency using the electronic tongue. Eur. J. Pharm. Biopharm. 66 (2007) 460-465
12. Krismundsdóttir T., Gudmundsson O.S., and Ingvarsdóttir K. Release of dilitiazem from Eudragit microparticles prepared by spray-drying. Int. J. Pharm. 133 (1996) 159-165
13. Lieberman A., Lachman L., and Schwartz J.B. Chapter 6 of Pharmaceutical Dosage Forms: Tablets. 2nd Ed. vol. I (1989), Dekker, New York
14. Raffin R.P., Jornada D.S., Inêsré M., Pohlmann A.R., and Guterres S.S. Sodium pantoprazole-loaded enteric microparticles prepared by spray drying: effect of the scale of production and process validation. Int. J. Pharm. 324 (2006) 10-18
15. Raghavendra C.M., Namdev B.Sh., Ajit P.R., Sangamesh A.P., and Tejraj M.A. Formulation and in-vitro evaluation of novel starch-based tableted microspheres for controlled release of ampicillin. Carbohydr. Polym. 71 (2008) 42-53
16. Robson H., Craig D.Q.M., and Deutsch D. An investigation into the release of cefuroxime axetil from taste-masked stearic acid microspheres. II. The effects of buffer composition on drug release. Int. J. Pharm. 195 (2000) 137-145
17. Robson H., Craig D.Q.M., and Deutsch D. An investigation into the release of cefuroxime axetil from taste-masked stearic acid microspheres. III. The use of DSC and HSDSC as means of characterising the interaction of the microspheres with buffered media. Int. J. Pharm. 201 (2000) 211-219
18. Robson H., Craig D.Q.M., and Deutsch D. An investigation into the release of cefuroxime axetil from taste-masked stearic acid microspheres. Part 1. The influence of the choice of dissolution media on drug release. Int. J. Pharm. 190 (1999) 183-192
19. Seville P.C., Learoyd T.P., Li H.Y., Williamson I.J., and Birchall J.C. Amino acid-modified spray-dried powders with enhanced aerosolisation properties for pulmonary drug delivery. Powder Technol. 178 (2007) 40-50
20. Shishu B.A., and Singh T. Preparation of tablets rapidly disintegrating in saliva containing bitter taste-masked granules by compression method. Indian J. Pharm. Sci. 69 (2007) 80-84
21. Siewert, et al. FIP/AAPS guidelines for dissolution/in vitro release testing of novel/special dosage forms. AAPS Pharm. Sci. Technol. 4 (2003) article 7
22. Soppimath K.S., Kulkarni A.R., and Aminabhavi T.M. Encapsulation of antihypertensive drugs in cellulose-based matrix microspheres: characterization and release kinetics of microspheres and tableted microspheres. J. Microencapsul. 18 (2001) 397-409
23. Sveinsson S.J., Kristmundsdóttir T., and Ingvarsdóttir K. The effect of tableting on the release characteristics of naproxen and ibuprofen microcapsules. Int. J. Pharm. 92 (1993) 29-34
24. Vikas A., Mahesh K., Vipin K., Vandana S., and Pratim K.C. The latest trends in the taste assessment of pharmaceuticals. Drug Discov. Today 12 (2007) 257-265
25. Vilivalam V.D., and Adeyeye C.M. Development and evaluation of controlled-release diclofenac microspheres and tableted microspheres. J. Microencapsul. 11 (1994) 455-470