The effect of the aqueous solubility of xanthine derivatives on the release mechanism from ethylcellulose matrix tablets

International Journal of Pharmaceutics

Volumn 179, Issue 1, 1999, Pages 97-105

  Neau, Steven H ^a   Howard, Matthew A ^a   Claudius, John S ^b   Howard, Danny R ^b  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b SANOFI   (France)

Author keywords

Caffeine; Drug release equations; Dyphylline; Ethylcellulose; Release mechanism; Theophylline

Indexed keywords

CAFFEINE; DIPROPHYLLINE; ETHYL CELLULOSE; THEOPHYLLINE; XANTHINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DIFFUSION; DIFFUSION COEFFICIENT; DISSOLUTION; DRUG DIFFUSION; DRUG RELEASE; DRUG SOLUBILITY; MATRIX TABLET; MODEL; NONHUMAN; PRIORITY JOURNAL; TABLET HARDNESS;

ALGORITHMS; CAFFEINE; CELLULOSE; DYPHYLLINE; KINETICS; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; TABLETS; THEOPHYLLINE; XANTHINES;

EID: 0032966414     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00391-3     Document Type: Article

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