The thalidomide analgesic effect is associated with differential TNF-α receptor expression in the dorsal horn of the spinal cord as studied in a rat model of neuropathic pain

Brain Research

Volumn 1450, Issue , 2012, Pages 24-32

  Andrade, Pablo ^a,b,c,d   Visser Vandewalle, Veerle ^b,c,d   Del Rosario, John S ^e   Daemen, Marc A ^f   Buurman, Wim A ^a   Steinbusch, Harry W ^a,c   Hoogland, Govert ^a,b,c,d  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c European Graduate School of Neuroscience   (Netherlands)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e CITY COLLEGE OF NEW YORK   (United States)

^f Kliniek Klein Rosendael   (Netherlands)

Author keywords

Chronic constriction injury; Neuropathic pain; Thalidomide; TNF alpha; TNFR1; TNFR2

Indexed keywords

1 [2 (BENZHYDRYLIDENEAMINOOXY)ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; MESSENGER RNA; SODIUM CHLORIDE; SOMATOMEDIN C; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TUMOR NECROSIS FACTOR ALPHA RECEPTOR 1; TUMOR NECROSIS FACTOR ALPHA RECEPTOR 2; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERSENSITIVITY; MALE; NERVE COMPRESSION; NEUROPATHIC PAIN; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCIATIC NERVE; SPINAL CORD DORSAL HORN; WESTERN BLOTTING;

ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; HYPERALGESIA; MALE; NEURALGIA; PAIN MEASUREMENT; POSTERIOR HORN CELLS; RATS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; SCIATIC NEUROPATHY; SPINAL CORD; THALIDOMIDE;

ANIMALIA; RATTUS;

EID: 84859430354     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.02.033     Document Type: Article

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