메뉴 건너뛰기




Volumn 25, Issue SUPPL. 1, 2012, Pages 30-34

Autophagy in hypoxia-ischemia induced brain injury

Author keywords

Apoptosis; Autophagy; Hypoxia; Hypoxic ischemic encephalopathy; Ischemia; Necrosis; Neonate; Neuroprotection

Indexed keywords

BECLIN 1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DANSYLCADAVERINE; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN;

EID: 84859410532     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767058.2012.663176     Document Type: Article
Times cited : (85)

References (46)
  • 1
    • 35448981935 scopus 로고    scopus 로고
    • Autophagy: From phenomenology to molecular understanding in less than a decade
    • DOI 10.1038/nrm2245, PII NRM2245
    • Klionsky DJ. Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 2007;8:931-937. (Pubitemid 47622558)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.11 , pp. 931-937
    • Klionsky, D.J.1
  • 3
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: Renovation of cells and tissues
    • Mizushima N, Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011;147:728-741.
    • (2011) Cell , vol.147 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 4
    • 0042691506 scopus 로고    scopus 로고
    • Autophagy genes are essential for dauer development and life-span extension in C. elegans
    • DOI 10.1126/science.1087782
    • Meléndez A, Tallóczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 2003;301:1387-1391. (Pubitemid 37075816)
    • (2003) Science , vol.301 , Issue.5638 , pp. 1387-1391
    • Melendez, A.1    Talloczy, Z.2    Seaman, M.3    Eskelinen, E.-L.4    Hall, D.H.5    Levine, B.6
  • 5
    • 78650890352 scopus 로고    scopus 로고
    • Regulation of autophagy by ROS: Physiology and pathology
    • Scherz-Shouval R, Elazar Z. Regulation of autophagy by ROS: physiology and pathology. Trends Biochem Sci 2011;36:30-38.
    • (2011) Trends Biochem Sci , vol.36 , pp. 30-38
    • Scherz-Shouval, R.1    Elazar, Z.2
  • 6
    • 33744905803 scopus 로고    scopus 로고
    • Autophagy: A novel protective mechanism in chronic ischemia
    • Yan L, Sadoshima J, Vatner DE, Vatner SF. Autophagy: a novel protective mechanism in chronic ischemia. Cell Cycle 2006;5:1175-1177. (Pubitemid 43845376)
    • (2006) Cell Cycle , vol.5 , Issue.11 , pp. 1175-1177
    • Yan, L.1    Sadoshima, J.2    Vatner, D.E.3    Vatner, S.F.4
  • 8
    • 56349126024 scopus 로고    scopus 로고
    • Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury
    • Carloni S, Buonocore G, Balduini W. Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury. Neurobiol Dis 2008;32:329-339.
    • (2008) Neurobiol Dis , vol.32 , pp. 329-339
    • Carloni, S.1    Buonocore, G.2    Balduini, W.3
  • 9
    • 36549041882 scopus 로고    scopus 로고
    • Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death
    • DOI 10.1016/j.nbd.2007.08.005, PII S0969996107001921
    • Rami A, Langhagen A, Steiger S. Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death. Neurobiol Dis 2008;29:132-141. (Pubitemid 350186114)
    • (2008) Neurobiology of Disease , vol.29 , Issue.1 , pp. 132-141
    • Rami, A.1    Langhagen, A.2    Steiger, S.3
  • 10
    • 0034757896 scopus 로고    scopus 로고
    • A novel assay to study autophagy: Regulation of autophagosome vacuole size by amino acid deprivation
    • Munafó DB, Colombo MI. A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. J Cell Sci 2001;114:3619-3629. (Pubitemid 33041044)
    • (2001) Journal of Cell Science , vol.114 , Issue.20 , pp. 3619-3629
    • Munafo, D.B.1    Colombo, M.I.2
  • 13
    • 33644604875 scopus 로고    scopus 로고
    • Neurodegeneration induces upregulation of Beclin 1
    • Erlich S, Shohami E, Pinkas-Kramarski R. Neurodegeneration induces upregulation of Beclin 1. Autophagy 2006;2:49-51.
    • (2006) Autophagy , vol.2 , pp. 49-51
    • Erlich, S.1    Shohami, E.2    Pinkas-Kramarski, R.3
  • 14
    • 0028924890 scopus 로고
    • Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis
    • Nitatori T, Sato N, Waguri S, Karasawa Y, Araki H, Shibanai K, Kominami E, Uchiyama Y. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J Neurosci 1995;15:1001-1011.
    • (1995) J Neurosci , vol.15 , pp. 1001-1011
    • Nitatori, T.1    Sato, N.2    Waguri, S.3    Karasawa, Y.4    Araki, H.5    Shibanai, K.6    Kominami, E.7    Uchiyama, Y.8
  • 15
    • 33644840693 scopus 로고    scopus 로고
    • Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
    • Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005;1:112-119.
    • (2005) Nat Chem Biol , vol.1 , pp. 112-119
    • Degterev, A.1    Huang, Z.2    Boyce, M.3    Li, Y.4    Jagtap, P.5    Mizushima, N.6    Cuny, G.D.7
  • 16
    • 70350059677 scopus 로고    scopus 로고
    • Postischemic treatment of neonatal cerebral ischemia should target autophagy
    • Puyal J, Vaslin A, Mottier V, Clarke PG. Postischemic treatment of neonatal cerebral ischemia should target autophagy. Ann Neurol 2009;66:378-389.
    • (2009) Ann Neurol , vol.66 , pp. 378-389
    • Puyal, J.1    Vaslin, A.2    Mottier, V.3    Clarke, P.G.4
  • 20
    • 77953727786 scopus 로고    scopus 로고
    • Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective efect of rapamycin in neonatal hypoxia-ischemia
    • Carloni S, Girelli S, Scopa C, Buonocore G, Longini M, Balduini W. Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective efect of rapamycin in neonatal hypoxia-ischemia. Autophagy 2010;6:366-377.
    • (2010) Autophagy , vol.6 , pp. 366-377
    • Carloni, S.1    Girelli, S.2    Scopa, C.3    Buonocore, G.4    Longini, M.5    Balduini, W.6
  • 21
    • 79960262514 scopus 로고    scopus 로고
    • Autophagy activation is involved in neuroprotection induced by hyperbaric oxygen preconditioning against focal cerebral ischemia in rats
    • Yan W, Zhang H, Bai X, Lu Y, Dong H, Xiong L. Autophagy activation is involved in neuroprotection induced by hyperbaric oxygen preconditioning against focal cerebral ischemia in rats. Brain Res 2011;1402:109-121.
    • (2011) Brain Res , vol.1402 , pp. 109-121
    • Yan, W.1    Zhang, H.2    Bai, X.3    Lu, Y.4    Dong, H.5    Xiong, L.6
  • 22
    • 77953699438 scopus 로고    scopus 로고
    • Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning
    • Sheng R, Zhang LS, Han R, Liu XQ, Gao B, Qin ZH. Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning. Autophagy 2010;6:482-494.
    • (2010) Autophagy , vol.6 , pp. 482-494
    • Sheng, R.1    Zhang, L.S.2    Han, R.3    Liu, X.Q.4    Gao, B.5    Qin, Z.H.6
  • 23
    • 9144257446 scopus 로고    scopus 로고
    • Ho CJ. cAMP response element-binding protein activation in ligation preconditioning in neonatal brain
    • Lee HT, Chang YC, Wang LY, Wang ST, Huang CC, Ho CJ. cAMP response element-binding protein activation in ligation preconditioning in neonatal brain. Ann Neurol 2004;56:611-623.
    • (2004) Ann Neurol , vol.56 , pp. 611-623
    • Lee, H.T.1    Chang, Y.C.2    Wang, L.Y.3    Wang, S.T.4    Huang, C.C.5
  • 24
    • 70349742221 scopus 로고    scopus 로고
    • Simvastatin acutely reduces ischemic brain damage in the immature rat via Akt and CREB activation
    • Carloni S, Girelli S, Buonocore G, Longini M, Balduini W. Simvastatin acutely reduces ischemic brain damage in the immature rat via Akt and CREB activation. Exp Neurol 2009;220:82-89.
    • (2009) Exp Neurol , vol.220 , pp. 82-89
    • Carloni, S.1    Girelli, S.2    Buonocore, G.3    Longini, M.4    Balduini, W.5
  • 25
    • 33947494524 scopus 로고    scopus 로고
    • Preconditioning suppresses inflammation in neonatal hypoxic ischemia via Akt activation
    • DOI 10.1161/01.STR.0000258102.18836.ca, PII 0000767020070300000040
    • Yin W, Signore AP, Iwai M, Cao G, Gao Y, Johnnides MJ, Hickey RW, Chen J. Preconditioning suppresses infammation in neonatal hypoxic ischemia via Akt activation. Stroke 2007;38:1017-1024. (Pubitemid 46568468)
    • (2007) Stroke , vol.38 , Issue.3 , pp. 1017-1024
    • Yin, W.1    Signore, A.P.2    Iwai, M.3    Cao, G.4    Gao, Y.5    Johnnides, M.J.6    Hickey, R.W.7    Chen, J.8
  • 27
    • 0035028936 scopus 로고    scopus 로고
    • Early neurodegeneration after hypoxia-ischemia in neonatal rat is necrosis while delayed neuronal death is apoptosis
    • DOI 10.1006/nbdi.2000.0371
    • Northington FJ, Ferriero DM, Graham EM, Traystman RJ, Martin LJ. Early Neurodegeneration afer Hypoxia-Ischemia in Neonatal Rat Is Necrosis while Delayed Neuronal Death Is Apoptosis. Neurobiol Dis 2001;8:207-219. (Pubitemid 32382476)
    • (2001) Neurobiology of Disease , vol.8 , Issue.2 , pp. 207-219
    • Northington, F.J.1    Ferriero, D.M.2    Graham, E.M.3    Traystman, R.J.4    Martin, L.J.5
  • 28
    • 36248945038 scopus 로고    scopus 로고
    • Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as "continuum" phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain
    • DOI 10.1016/j.neuroscience.2007.06.060, PII S0306452207008573
    • Northington FJ, Zelaya ME, O'Riordan DP, Blomgren K, Flock DL, Hagberg H, Ferriero DM, Martin LJ. Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as "continuum" phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain. Neuroscience 2007;149:822-833. (Pubitemid 350130287)
    • (2007) Neuroscience , vol.149 , Issue.4 , pp. 822-833
    • Northington, F.J.1    Zelaya, M.E.2    O'Riordan, D.P.3    Blomgren, K.4    Flock, D.L.5    Hagberg, H.6    Ferriero, D.M.7    Martin, L.J.8
  • 29
    • 0042164446 scopus 로고    scopus 로고
    • Intravenously administered propidium iodide labels necrotic cells in the intact mouse brain after injury [1]
    • DOI 10.1038/sj.cdd.4401250
    • Unal Cevik I, Dalkara T. Intravenously administered propidium iodide labels necrotic cells in the intact mouse brain afer injury. Cell Death Difer 2003;10:928-929. (Pubitemid 36939703)
    • (2003) Cell Death and Differentiation , vol.10 , Issue.8 , pp. 928-929
    • Cevik, U.1    Dalkara, T.2
  • 30
    • 34548216176 scopus 로고    scopus 로고
    • Extended role of necrotic cell death after hypoxia-ischemia-induced neurodegeneration in the neonatal rat
    • DOI 10.1016/j.nbd.2007.06.009, PII S0969996107001155
    • Carloni S, Carnevali A, Cimino M, Balduini W. Extended role of necrotic cell death afer hypoxia-ischemia-induced neurodegeneration in the neonatal rat. Neurobiol Dis 2007;27:354-361. (Pubitemid 47333193)
    • (2007) Neurobiology of Disease , vol.27 , Issue.3 , pp. 354-361
    • Carloni, S.1    Carnevali, A.2    Cimino, M.3    Balduini, W.4
  • 32
    • 0347747970 scopus 로고    scopus 로고
    • A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells
    • DOI 10.1016/S1535-6108(03)00303-9
    • Kau TR, Schroeder F, Ramaswamy S, Wojciechowski CL, Zhao JJ, Roberts TM, Clardy J, et al. A chemical genetic screen identifes inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-defcient tumor cells. Cancer Cell 2003;4:463-476. (Pubitemid 38050043)
    • (2003) Cancer Cell , vol.4 , Issue.6 , pp. 463-476
    • Kau, T.R.1    Schroeder, F.2    Ramaswamy, S.3    Wojciechowski, C.L.4    Zhao, J.J.5    Roberts, T.M.6    Clardy, J.7    Sellers, W.R.8    Silver, P.A.9
  • 33
    • 36049028936 scopus 로고    scopus 로고
    • The PI3K/Akt pathway mediates the neuroprotective effect of atorvastatin in extending thrombolytic therapy after embolic stroke in the rat
    • DOI 10.1161/ATVBAHA.107.150748, PII 0004360520071100000029
    • Zhang L, Zhang ZG, Liu XS, Hozeska-Solgot A, Chopp M. The PI3K/Akt pathway mediates the neuroprotective efect of atorvastatin in extending thrombolytic therapy afer embolic stroke in the rat. Arterioscler Tromb Vasc Biol 2007;27:2470-2475. (Pubitemid 350203966)
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , Issue.11 , pp. 2470-2475
    • Zhang, L.1    Zhang, Z.G.2    Liu, X.S.3    Hozeska-Solgot, A.4    Chopp, M.5
  • 34
    • 48249117115 scopus 로고    scopus 로고
    • Preconditioning induces prolonged expression of transcription factors pCREB and NF-kappa B in the neocortex of rats before and following severe hypobaric hypoxia
    • Rybnikova E, Gluschenko T, Tulkova E, Churilova A, Jaroshevich O, Baranova K, Samoilov M. Preconditioning induces prolonged expression of transcription factors pCREB and NF-kappa B in the neocortex of rats before and following severe hypobaric hypoxia. J Neurochem 2008;106:1450-1458.
    • (2008) J Neurochem , vol.106 , pp. 1450-1458
    • Rybnikova, E.1    Gluschenko, T.2    Tulkova, E.3    Churilova, A.4    Jaroshevich, O.5    Baranova, K.6    Samoilov, M.7
  • 35
    • 84856457651 scopus 로고    scopus 로고
    • Carloni S, Buonocore G, Longini M, Proietti F, Balduini W. Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation. Neuroscience 2012. Available from http://dx.doi.org/10.1016/j.neuroscience.2011.12.021
  • 37
    • 3042651558 scopus 로고    scopus 로고
    • Trauma-hemorrhagic shock mesenteric lymph induces endothelial apoptosis that involves both caspase-dependent and caspase-independent mechanisms
    • DOI 10.1097/01.sla.0000129341.94219.cf
    • Davidson MT, Deitch EA, Lu Q, Haskó G, Abungu B, Németh ZH, Zaets SB, et al. Trauma-hemorrhagic shock mesenteric lymph induces endothelial apoptosis that involves both caspase-dependent and caspase-independent mechanisms. Ann Surg 2004;240:123-131. (Pubitemid 38808244)
    • (2004) Annals of Surgery , vol.240 , Issue.1 , pp. 123-131
    • Davidson, M.T.1    Deitch, E.A.2    Lu, Q.3    Hasko, G.4    Abungu, B.5    Nemeth, Z.H.6    Zaets, S.B.7    Gaspers, L.D.8    Thomas, A.P.9    Xu, D.-Z.10
  • 39
    • 27844480078 scopus 로고    scopus 로고
    • Apoptosis in perinatal hypoxic-ischemic brain injury: How important is it and should it be inhibited?
    • DOI 10.1016/j.brainresrev.2005.07.003, PII S0165017305001128
    • Northington FJ, Graham EM, Martin LJ. Apoptosis in perinatal hypoxic-ischemic brain injury: how important is it and should it be inhibited? Brain Res Brain Res Rev 2005;50:244-257. (Pubitemid 41654395)
    • (2005) Brain Research Reviews , vol.50 , Issue.2 , pp. 244-257
    • Northington, F.J.1    Graham, E.M.2    Martin, L.J.3
  • 40
    • 79958172986 scopus 로고    scopus 로고
    • Huang C, Andres AM, Ratlif EP, Hernandez G, Lee P, Gottlieb RA. Preconditioning involves selective mitophagy mediated by parkin and e20975. doi:10.1371/journal.pone.0020975.
  • 41
    • 68349118949 scopus 로고    scopus 로고
    • The neuroprotective mechanism of brain ischemic preconditioning
    • Liu XQ, Sheng R, Qin ZH. The neuroprotective mechanism of brain ischemic preconditioning. Acta Pharmacol Sin 2009;30: 1071-1080.
    • (2009) Acta Pharmacol Sin , vol.30 , pp. 1071-1080
    • Liu, X.Q.1    Sheng, R.2    Qin, Z.H.3
  • 42
    • 73849114180 scopus 로고    scopus 로고
    • Enhancement of autophagic fux afer neonatal cerebral hypoxia-ischemia and its region-specifc relationship to apoptotic mechanisms
    • Ginet V, Puyal J, Clarke PG, Truttmann AC. Enhancement of autophagic fux afer neonatal cerebral hypoxia-ischemia and its region-specifc relationship to apoptotic mechanisms. Am J Pathol 2009;175:1962-1974.
    • (2009) Am J Pathol , vol.175 , pp. 1962-1974
    • Ginet, V.1    Puyal, J.2    Clarke, P.G.3    Truttmann, A.C.4
  • 43
    • 70349647603 scopus 로고    scopus 로고
    • Targeting autophagy to prevent neonatal stroke damage
    • Puyal J, Clarke PG. Targeting autophagy to prevent neonatal stroke damage. Autophagy 2009;5:1060-1061.
    • (2009) Autophagy , vol.5 , pp. 1060-1061
    • Puyal, J.1    Clarke, P.G.2
  • 44
    • 70350059677 scopus 로고    scopus 로고
    • Postischemic treatment of neonatal cerebral ischemia should target autophagy
    • Puyal J, Vaslin A, Mottier V, Clarke PGH. Postischemic treatment of neonatal cerebral ischemia should target autophagy. Annals of Neurology 2009;66:378-389.
    • (2009) Annals of Neurology , vol.66 , pp. 378-389
    • Puyal, J.1    Vaslin, A.2    Mottier, V.3    Clarke, P.G.H.4
  • 45
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Difer 2011;18:571-580.
    • (2011) Cell Death Difer , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.