Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment

Toxicology Letters

Volumn 211, Issue 1, 2012, Pages 70-76

  Liu, Xiaoshan ^a   Lee, Jinyoung ^a   Ji, Kyunghee ^a   Takeda, Shunichi ^b   Choi, Kyungho ^a  

^a Seoul National University   (South Korea)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

H2AX; Chicken DT40 cell; Chromosome aberration; Genotoxicity; Pharmaceutical

Indexed keywords

CHLORTETRACYCLINE; DICLOFENAC; DOUBLE STRANDED DNA; ERYTHROMYCIN; HISTONE H2AX; OXYTETRACYCLINE; RAD54 PROTEIN; SULFADIMIDINE; SULFATHIAZOLE; SURFACE WATER; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINE; CHICKEN; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CONTROLLED STUDY; COVALENT BOND; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA SYNTHESIS; EXCISION REPAIR; FRESHWATER ENVIRONMENT; GENE LOCUS; GENOTOXICITY; GROWTH RATE; HOMOLOGOUS RECOMBINATION; KINETICS; MUTAGENESIS; MUTANT; NONHUMAN; PRIORITY JOURNAL; ULTRAVIOLET RADIATION; WILD TYPE;

ANIMALS; CELL LINE; CHICKENS; CHLORTETRACYCLINE; CHROMOSOME ABERRATIONS; DICLOFENAC; DNA; DNA REPAIR; DNA REPLICATION; ERYTHROMYCIN; FRESH WATER; MUTAGENICITY TESTS; MUTATION; OXYTETRACYCLINE; SULFAMETHAZINE; SULFATHIAZOLES; WATER POLLUTANTS, CHEMICAL;

EID: 84859332689     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.03.003     Document Type: Article

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