Thermodynamic studies for drug design and screening

Expert Opinion on Drug Discovery

Volumn 7, Issue 4, 2012, Pages 299-314

  Garbett, Nichola C ^a   Chaires, Jonathan B ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

affinity; binding; calorimetry; drug design and development; DSC; energetics; enthalpy; entropy; free energy; ITC; ligand; molecular interactions; screening; thermal shift assay; thermodynamics

Indexed keywords

BINDING AFFINITY; CALORIMETRY; CORRELATION ANALYSIS; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DESIGN; DRUG SCREENING; ENTHALPY; FLUORESCENCE ANALYSIS; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; REVIEW; THERMODYNAMICS;

BINDING SITES; CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; FLUORESCENCE; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; THERMODYNAMICS;

EID: 84859313336     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2012.666235     Document Type: Review

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