Calorimetry as a tool for understanding biomolecular interactions and an aid to drug design

Biochemical Society Transactions

Volumn 38, Issue 4, 2010, Pages 888-893

  Ladbury, John E ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Biomolecular interaction; Drug design; Enthalpic efficiency; Isothermal titration calorimetry (ITC); Lead optimization

Indexed keywords

PEPTIDOMIMETIC AGENT;

AMINO ACID SEQUENCE; CALORIMETRY; CHEMICAL STRUCTURE; COMPLEX FORMATION; DRUG DESIGN; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; REVIEW; THERMODYNAMICS;

ANIMALS; CALORIMETRY; COMPREHENSION; DRUG DESIGN; DRUG INTERACTIONS; HUMANS; LIGANDS; MACROMOLECULAR SUBSTANCES; MODELS, BIOLOGICAL; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; THERMODYNAMICS;

EID: 77955971738     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0380888     Document Type: Review

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