Neurite outgrowth stimulated by neural cell adhesion molecules requires growth-associated protein-43 (GAP-43) function and is associated with GAP-43 phosphorylation in growth cones

Journal of Neuroscience

Volumn 18, Issue 24, 1998, Pages 10429-10437

  Meiri, Karina F ^a   Saffell, Jane L ^b   Walsh, Frank S ^a   Doherty, Patrick ^b  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

FGF receptor; GAP 43; Growth cone; Knock out mouse; NCAM; Neurite outgrowth

Indexed keywords

NEUROMODULIN; PROTEIN KINASE C;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CELL CULTURE; CHIMERA; ELECTROPHORESIS; GRANULE CELL; GROWTH CONE; MOUSE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STEADY STATE; WESTERN BLOTTING;

EID: 0032535703     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-24-10429.1998     Document Type: Article

References (5)

1. Aigner L, Caroni P (1993) Depletion of 43 kDa growth-associated protein in primary sensory neurons leads to diminished formation and spreading of growth cones. J Cell Biol 123:417-429.
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3. Apel ED, Byford M, Au D, Walsh K, Storm D (1990) The identification of the protein kinase C site in neuromodulin. Biochemistry 29:2330-2335.
4. Benowitz LI, Routtenberg A (1997) GAP-43: an intrinsic determinant of neuronal development and plasticity. Trends Neurosci 20:84-91.
5. Brittis PA, Silver J, Walsh FS, Doherty P (1996) Fibroblast growth factor receptor function is required for the orderly projection of ganglion cell axons in the developing mammalian retina. Mol Cell Neurosci 8:120-128.