SCOPUS 정보 검색 플랫폼

Organic and Biomolecular Chemistry

Volumn 10, Issue 16, 2012, Pages 3288-3299

Synthesis and evaluation of novel aza-caged Garcinia xanthones

(8) Zhang, Xiaojin a Li, Xiang a Sun, Haopeng b Jiang, Zhengyu b Tao, Lei b Gao, Yuan b Guo, Qinglong b You, Qidong a,b

a China Pharmaceutical University (China)

b CHINA PHARMACEUTICAL UNIVERSITY (China)

Author keywords

[No Author keywords available]

Indexed keywords

A549 CELLS; BINDING MODES; CASCADE REACTIONS; CELL CYCLE; CHEMICAL STRATEGY; DFT METHOD; HYDROPHOBIC MOIETIES; INHIBITORY ACTIVITY; MOLECULAR DOCKING; REGIO-SELECTIVE; S-PHASE; THERAPEUTIC POTENTIALS;

BINDING ENERGY; CELL DEATH; CELL PROLIFERATION;

REGIOSELECTIVITY;

ANTINEOPLASTIC AGENT; HETEROCYCLIC COMPOUND; I KAPPA B KINASE; XANTHONE DERIVATIVE;

ARTICLE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GARCINIA; HUMAN; METABOLISM; NEOPLASM; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; AZA COMPOUNDS; CELL LINE, TUMOR; CELL PROLIFERATION; GARCINIA; HUMANS; I-KAPPA B KINASE; MODELS, MOLECULAR; NEOPLASMS; XANTHONES;

ALNUS; GARCINIA;

EID: 84859221029 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/c2ob07088j Document Type: Article

Times cited : (24)

References (52)

1
- 31844445117
- H. Auterhoff H. Frauendorf W. liesenklas C. Schwandt Arch. Pharm. 1962 295 833 846
- (1962) Arch. Pharm. , vol.295 , pp. 833-846
- Auterhoff, H.¹ Frauendorf, H.² Liesenklas, W.³ Schwandt, C.⁴

2
- 0012725780
- W. D. Ollis B. T. Redman I. O. Sutherland K. Jewers J. Chem. Soc. D 1969 879 880
- (1969) J. Chem. Soc. D , pp. 879-880
- Ollis, W.D.¹ Redman, B.T.² Sutherland, I.O.³ Jewers, K.⁴

3
- 0018962590
- P. Kumar P. K. Baslas Herba Hungarica 1980 19 81 91
- (1980) Herba Hungarica , vol.19 , pp. 81-91
- Kumar, P.¹ Baslas, P.K.²

4
- 0001052053
- W. D. Ollis M. V. J. Ramsy I. O. Sutherland S. Mongkolsuk Tetrahedron 1965 21 1453 1470
- (1965) Tetrahedron , vol.21 , pp. 1453-1470
- Ollis, W.D.¹ Ramsy, M.V.J.² Sutherland, I.O.³ Mongkolsuk, S.⁴

5
- 0001040281
- C. G. Karanjgaonkar P. M. Nair K. Venkartaraman Tetrahedron Lett. 1966 7 687 691
- (1966) Tetrahedron Lett. , vol.7 , pp. 687-691
- Karanjgaonkar, C.G.¹ Nair, P.M.² Venkartaraman, K.³

6
- 0030087854
- J. Asano K. Chiba M. Tada T. Yoshii Photochemistry 1996 41 815 820
- (1996) Photochemistry , vol.41 , pp. 815-820
- Asano, J.¹ Chiba, K.² Tada, M.³ Yoshii, T.⁴

7
- 70450197675
- Q. B. Han H. X. Xu Curr. Med. Chem. 2009 16 3775 3796
- (2009) Curr. Med. Chem. , vol.16 , pp. 3775-3796
- Han, Q.B.¹ Xu, H.X.²

8
- 72449198215
- Q. Guo Q. Qi Q. You H. Gu L. Zhao Z. Wu Basic Clin. Pharmacol. Toxicol. 2001 31 178 184
- (2001) Basic Clin. Pharmacol. Toxicol. , vol.31 , pp. 178-184
- Guo, Q.¹ Qi, Q.² You, Q.³ Gu, H.⁴ Zhao, L.⁵ Wu, Z.⁶

9
- 0347320714
- H. Z. Zhang S. Kasibhatla Y. Wang J. Herich J. Guastella B. Tseng J. Drewe S. X. Cai Bioorg. Med. Chem. 2004 12 309 317
- (2004) Bioorg. Med. Chem. , vol.12 , pp. 309-317
- Zhang, H.Z.¹ Kasibhatla, S.² Wang, Y.³ Herich, J.⁴ Guastella, J.⁵ Tseng, B.⁶ Drewe, J.⁷ Cai, S.X.⁸

10
- 51749101694
- H. Gu Q. You W. Liu Y. Yang L. Zhao Q. Qi J. Zhao J. Wang N. Lu H. Ling Q. Guo X. Wang Int. Immunopharmacol. 2008 8 1493 1502
- (2008) Int. Immunopharmacol. , vol.8 , pp. 1493-1502
- Gu, H.¹ You, Q.² Liu, W.³ Yang, Y.⁴ Zhao, L.⁵ Qi, Q.⁶ Zhao, J.⁷ Wang, J.⁸ Lu, N.⁹ Ling, H.¹⁰ Guo, Q.¹¹ Wang, X.¹²

11
- 72949086591
- L. Zhao Q. L. Guo Q. D. You Z. Q. Wu H. Y. Gu Drug Chem. Toxicol. 2010 33 88 96
- (2010) Drug Chem. Toxicol. , vol.33 , pp. 88-96
- Zhao, L.¹ Guo, Q.L.² You, Q.D.³ Wu, Z.Q.⁴ Gu, H.Y.⁵

12
- 48049101768
- T. W. Zhou Chin. J. New Drugs 2007 16 79 82
- (2007) Chin. J. New Drugs , vol.16 , pp. 79-82
- Zhou, T.W.¹

13
- 9644266405
- L. Zhao Q. L. Guo Q. D. You Z. Q. Wu H. Y. Gu Biol. Pharm. Bull. 2004 27 998 1003
- (2004) Biol. Pharm. Bull. , vol.27 , pp. 998-1003
- Zhao, L.¹ Guo, Q.L.² You, Q.D.³ Wu, Z.Q.⁴ Gu, H.Y.⁵

14
- 67349089550
- F. Nie X. Zhang Q. Qi L. Yang Y. Yang W. Liu N. Lu Z. Wu Q. You Q. Guo Toxicology 2009 260 60 67
- (2009) Toxicology , vol.260 , pp. 60-67
- Nie, F.¹ Zhang, X.² Qi, Q.³ Yang, L.⁴ Yang, Y.⁵ Liu, W.⁶ Lu, N.⁷ Wu, Z.⁸ You, Q.⁹ Guo, Q.¹⁰

15
- 69049088724
- J. J. Rong R. Hu Q. Qi H. Y. Gu Q. Zhao J. Wang R. Mu Q. D. You Q. L. Guo Cancer Lett. 2009 284 102 112
- (2009) Cancer Lett. , vol.284 , pp. 102-112
- Rong, J.J.¹ Hu, R.² Qi, Q.³ Gu, H.Y.⁴ Zhao, Q.⁵ Wang, J.⁶ Mu, R.⁷ You, Q.D.⁸ Guo, Q.L.⁹

16
- 78651460233
- H. Huang D. Chen S. Li X. Li N. Liu X. Lu S. Liu K. Zhao H. Guo C. Yang P. Zhou X. Dong C. Zhang Guanmei Q. P. Dou J. Liu Cancer Lett. 2011 301 221 228
- (2011) Cancer Lett. , vol.301 , pp. 221-228
- Huang, H.¹ Chen, D.² Li, S.³ Li, X.⁴ Liu, N.⁵ Lu, X.⁶ Liu, S.⁷ Zhao, K.⁸ Guo, H.⁹ Yang, C.¹⁰ Zhou, P.¹¹ Dong, X.¹² Zhang, C.¹³ Guanmei¹⁴ Dou, Q.P.¹⁵ Liu, J.¹⁶

17
- 34047133853
- J. Yu Q. L. Guo Q. D. You L. Zhao H. Y. Gu Y. Yang H. W. Zhang Z. Tan X. Wang Carcinogenesis 2007 28 632 638
- (2007) Carcinogenesis , vol.28 , pp. 632-638
- Yu, J.¹ Guo, Q.L.² You, Q.D.³ Zhao, L.⁴ Gu, H.Y.⁵ Yang, Y.⁶ Zhang, H.W.⁷ Tan, Z.⁸ Wang, X.⁹

18
- 77958573005
- Y. Liu W. Li C. Ye Y. Lin T. Y. Cheng M. Wang H. Zhang S. Wang L. Zhang S. Wang J. Atheroscler. Thromb. 2010 17 901 913
- (2010) J. Atheroscler. Thromb. , vol.17 , pp. 901-913
- Liu, Y.¹ Li, W.² Ye, C.³ Lin, Y.⁴ Cheng, T.Y.⁵ Wang, M.⁶ Zhang, H.⁷ Wang, S.⁸ Zhang, L.⁹ Wang, S.¹⁰

19
- 35348952483
- N. Lu Y. Yang Q. D. You Y. Ling Y. Gao H. Y. Gu L. Zhao X. T. Wang Q. L. Guo Cancer Lett. 2007 258 80 89
- (2007) Cancer Lett. , vol.258 , pp. 80-89
- Lu, N.¹ Yang, Y.² You, Q.D.³ Ling, Y.⁴ Gao, Y.⁵ Gu, H.Y.⁶ Zhao, L.⁷ Wang, X.T.⁸ Guo, Q.L.⁹

20
- 38949176773
- L. Qiang Y. Yang Q. D. You Y. J. Ma L. Yang F. F. Nie H. Y. Hong L. Zhao N. Lu Q. Qi X. T. Wang Q. L. Guo Biochem. Pharmacol. 2008 75 1083 1092
- (2008) Biochem. Pharmacol. , vol.75 , pp. 1083-1092
- Qiang, L.¹ Yang, Y.² You, Q.D.³ Ma, Y.J.⁴ Yang, L.⁵ Nie, F.F.⁶ Hong, H.Y.⁷ Zhao, L.⁸ Lu, N.⁹ Qi, Q.¹⁰ Wang, X.T.¹¹ Guo, Q.L.¹²

21
- 40949101023
- T. Li Z. Yi S. G. Cho J. Luo M. K. Pandey B. B. Aggarwal M. Liu Cancer Res. 2008 68 1843 1850
- (2008) Cancer Res. , vol.68 , pp. 1843-1850
- Li, T.¹ Yi, Z.² Cho, S.G.³ Luo, J.⁴ Pandey, M.K.⁵ Aggarwal, B.B.⁶ Liu, M.⁷

22
- 80555131105
- C. Li N. Lu Q. Qi F. Li Y. Ling Y. Chen Y. Qin Z. Li H. Zhang Q. You Q. Guo Biochem. Pharmacol. 2011 82 1873 1883
- (2011) Biochem. Pharmacol. , vol.82 , pp. 1873-1883
- Li, C.¹ Lu, N.² Qi, Q.³ Li, F.⁴ Ling, Y.⁵ Chen, Y.⁶ Qin, Y.⁷ Li, Z.⁸ Zhang, H.⁹ You, Q.¹⁰ Guo, Q.¹¹

23
- 84859240824
- Y. C. Xin Q. B. Han C. Y. Chan H. Wang Z. Liu D. T. Y. Christopher H. K. Cheng H. X. Xu Proteomics 2009 9 242 253
- (2009) Proteomics , vol.9 , pp. 242-253
- Xin, Y.C.¹ Han, Q.B.² Chan, C.Y.³ Wang, H.⁴ Liu, Z.⁵ Christopher, D.T.Y.⁶ Cheng, H.K.⁷ Xu, H.X.⁸

24
- 78650173496
- L. Zhang Y. Yi J. Chen Y. Sun Q. Guo Z. Zheng S. Song Biochem. Biophys. Res. Commun. 2010 403 282 287
- (2010) Biochem. Biophys. Res. Commun. , vol.403 , pp. 282-287
- Zhang, L.¹ Yi, Y.² Chen, J.³ Sun, Y.⁴ Guo, Q.⁵ Zheng, Z.⁶ Song, S.⁷

25
- 79957799005
- J. Davenport J. R. Manjarrez L. Peterson B. Krumm B. S. Blagg R. L. Matts J. Nat. Prod. 2011 74 1085 1092
- (2011) J. Nat. Prod. , vol.74 , pp. 1085-1092
- Davenport, J.¹ Manjarrez, J.R.² Peterson, L.³ Krumm, B.⁴ Blagg, B.S.⁵ Matts, R.L.⁶

26
- 35349029248
- M. K. Pandey B. Sung K. S. Ahn A. B. Kunnumakkara M. M. Chaturvedi B. B. Aggarwal Blood 2007 110 3517 3525
- (2007) Blood , vol.110 , pp. 3517-3525
- Pandey, M.K.¹ Sung, B.² Ahn, K.S.³ Kunnumakkara, A.B.⁴ Chaturvedi, M.M.⁵ Aggarwal, B.B.⁶

27
- 24744435348
- S. Kasibhatla A. Jessen Katayoun S. Maliartchouk Y. W. Jean M. E. Nicole J. Drewe L. Qiu P. A. Shannon E. P. Anthony N. Sirisoma S. Jiang H. Z. Zhang R. G. Kurt X. C. Sui R. G. Douglas B. Tseng Proc. Natl. Acad. Sci. U. S. A. 2005 102 12095 12100
- (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 12095-12100
- Kasibhatla, S.¹ Jessen Katayoun, A.² Maliartchouk, S.³ Jean, Y.W.⁴ Nicole, M.E.⁵ Drewe, J.⁶ Qiu, L.⁷ Shannon, P.A.⁸ Anthony, E.P.⁹ Sirisoma, N.¹⁰ Jiang, S.¹¹ Zhang, H.Z.¹² Kurt, R.G.¹³ Sui, X.C.¹⁴ Douglas, R.G.¹⁵ Tseng, B.¹⁶

28
- 64249171904
- U. D. Palempalli U. Gandhi P. Kalantari H. Vunta R. J. Arner V. Narayan A. Ravindran K. S. Prabhu Biochem. J. 2009 419 401 409
- (2009) Biochem. J. , vol.419 , pp. 401-409
- Palempalli, U.D.¹ Gandhi, U.² Kalantari, P.³ Vunta, H.⁴ Arner, R.J.⁵ Narayan, V.⁶ Ravindran, A.⁷ Prabhu, K.S.⁸

29
- 72449141611
- Q. Chantarasriwong W. C. Cho A. Batowa W. Chavasiri C. Moore A. L. Rheingold E. A. Theodorakis Org. Biomol. Chem. 2009 7 4886 4894
- (2009) Org. Biomol. Chem. , vol.7 , pp. 4886-4894
- Chantarasriwong, Q.¹ Cho, W.C.² Batowa, A.³ Chavasiri, W.⁴ Moore, C.⁵ Rheingold, A.L.⁶ Theodorakis, E.A.⁷

30
- 79952283088
- X. Wang N. Lu Q. Yang D. Gong C. Lin S. Zhang M. Xi Y. Gao L. Wei Q. Guo Q. You Eur. J. Med. Chem. 2011 46 1280 1290
- (2011) Eur. J. Med. Chem. , vol.46 , pp. 1280-1290
- Wang, X.¹ Lu, N.² Yang, Q.³ Gong, D.⁴ Lin, C.⁵ Zhang, S.⁶ Xi, M.⁷ Gao, Y.⁸ Wei, L.⁹ Guo, Q.¹⁰ You, Q.¹¹

31
- 33846498459
- A. Batova T. Lam V. Wascholowski A. L. Yu A. Giannis E. A. Theodorakis Org. Biomol. Chem. 2007 5 494 500
- (2007) Org. Biomol. Chem. , vol.5 , pp. 494-500
- Batova, A.¹ Lam, T.² Wascholowski, V.³ Yu, A.L.⁴ Giannis, A.⁵ Theodorakis, E.A.⁶

32
- 42149140804
- J. Kuemmerle S. Jiang B. Tseng S. Kasibhatla J. Drewe S. X. Cai Bioorg. Med. Chem. 2008 16 4233 4241
- (2008) Bioorg. Med. Chem. , vol.16 , pp. 4233-4241
- Kuemmerle, J.¹ Jiang, S.² Tseng, B.³ Kasibhatla, S.⁴ Drewe, J.⁵ Cai, S.X.⁶

33
- 0035915152
- K. C. Nicolaou J. Li Angew. Chem., Int. Ed. 2001 40 4264 4268
- (2001) Angew. Chem., Int. Ed. , vol.40 , pp. 4264-4268
- Nicolaou, K.C.¹ Li, J.²

34
- 0346276879
- E. J. Tisdale I. Slobodov E. A. Theodorakis Org. Biomol. Chem. 2003 1 4418 4422
- (2003) Org. Biomol. Chem. , vol.1 , pp. 4418-4422
- Tisdale, E.J.¹ Slobodov, I.² Theodorakis, E.A.³

35
- 4344608504
- E. J. Tisdale I. Slobodov E. A. Theodorakis Proc. Natl. Acad. Sci. U. S. A. 2004 101 12030 12035
- (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 12030-12035
- Tisdale, E.J.¹ Slobodov, I.² Theodorakis, E.A.³

36
- 33645053651
- K. C. Nicolaou H. Xu M. Wartmann Angew. Chem. 2005 117 766 771
- (2005) Angew. Chem. , vol.117 , pp. 766-771
- Nicolaou, K.C.¹ Xu, H.² Wartmann, M.³

37
- 34547813047
- N. G. Li J. X. Wang X. R. Liu C. J. Lin Q. D. You Q. L. Guo Tetrahedron Lett. 2007 48 6586 6589
- (2007) Tetrahedron Lett. , vol.48 , pp. 6586-6589
- Li, N.G.¹ Wang, J.X.² Liu, X.R.³ Lin, C.J.⁴ You, Q.D.⁵ Guo, Q.L.⁶

38
- 80955177178
- Z. L. Liu X. J. Wang N. G. Li H. P. Sun J. X. Wang Q. D. You Tetrahedron 2011 57 4774 4779
- (2011) Tetrahedron , vol.57 , pp. 4774-4779
- Liu, Z.L.¹ Wang, X.J.² Li, N.G.³ Sun, H.P.⁴ Wang, J.X.⁵ You, Q.D.⁶

39
- 77956106042
- O. Chantarasriwong A. Batova W. Chavasiri E. A. Theodorakis Chem.-Eur. J. 2010 16 9944 9962
- (2010) Chem.-Eur. J. , vol.16 , pp. 9944-9962
- Chantarasriwong, O.¹ Batova, A.² Chavasiri, W.³ Theodorakis, E.A.⁴

40
- 65349102209
- V. Santagada F. Frecentese E. Perissutti F. Fiorino B. Severino G. Caliendo Mini-Rev. Med. Chem. 2009 9 340 358
- (2009) Mini-Rev. Med. Chem. , vol.9 , pp. 340-358
- Santagada, V.¹ Frecentese, F.² Perissutti, E.³ Fiorino, F.⁴ Severino, B.⁵ Caliendo, G.⁶

41
- 39749096519
- N. G. Li J. X. Wang Q. D. You G. Chu Q. L. Guo Chin. J. Chem. 2008 26 363 367
- (2008) Chin. J. Chem. , vol.26 , pp. 363-367
- Li, N.G.¹ Wang, J.X.² You, Q.D.³ Chu, G.⁴ Guo, Q.L.⁵

43
- 0004005645
- Butterworths, London, 2nd edn
- T. L. Cottrell, The Strengths of Chemical Bonds, Butterworths, London, 2nd edn, 1958
- (1958) The Strengths of Chemical Bonds
- Cottrell, T.L.¹

44
- 0039536622
- National Bureau of Standards, Washington, DC
- B. de B. Darwent, National Standard Reference Data Series, National Bureau of Standards, Washington, DC, 1970, vol. 31, pp. 1-48
- (1970) National Standard Reference Data Series , vol.31 , pp. 1-48
- Darwent, B.D.B.¹

45
- 33947483256
- S. W. Benson J. Chem. Educ. 1965 42 502 518
- (1965) J. Chem. Educ. , vol.42 , pp. 502-518
- Benson, S.W.¹

46
- 84859224527
- http://www.wiredchemist.com/chemistry/data/bond-energies-lengths

47
- 79955481873
- G. Xu Y. Lo Q. Li G. Napolitano X. Wu X. Jiang M. Dreano M. Karin H. Wu Nature 2011 472 325 330
- (2011) Nature , vol.472 , pp. 325-330
- Xu, G.¹ Lo, Y.² Li, Q.³ Napolitano, G.⁴ Wu, X.⁵ Jiang, X.⁶ Dreano, M.⁷ Karin, M.⁸ Wu, H.⁹

48
- 63149188726
- S. Nagarajan M. Doddareddy H. Choo Y. S. Cho K. S. Oh B. H. Lee A. N. Pae Bioorg. Med. Chem. 2009 17 2759 2766
- (2009) Bioorg. Med. Chem. , vol.17 , pp. 2759-2766
- Nagarajan, S.¹ Doddareddy, M.² Choo, H.³ Cho, Y.S.⁴ Oh, K.S.⁵ Lee, B.H.⁶ Pae, A.N.⁷

49
- 65649150796
- J. A. Christopher P. Bamborough C. Alder A. Campbell G. J. Cutler K. Down A. M. Hamadi A. M. Jolly J. K. Kerns F. S. Lucas G. W. Mellor D. D. Miller M. A. Morse K. D. Pancholi W. Rumsey Y. E. Solanke R. Williamson J. Med. Chem. 2009 52 3098 3102
- (2009) J. Med. Chem. , vol.52 , pp. 3098-3102
- Christopher, J.A.¹ Bamborough, P.² Alder, C.³ Campbell, A.⁴ Cutler, G.J.⁵ Down, K.⁶ Hamadi, A.M.⁷ Jolly, A.M.⁸ Kerns, J.K.⁹ Lucas, F.S.¹⁰ Mellor, G.W.¹¹ Miller, D.D.¹² Morse, M.A.¹³ Pancholi, K.D.¹⁴ Rumsey, W.¹⁵ Solanke, Y.E.¹⁶ Williamson, R.¹⁷

50
- 79952280173
- C. M. Avila A. B. Lopes A. S. Goncalves L. L. da Silva N. C. Romeiro A. L. P. Miranda C. M. R. SantAnna E. J. Barreiro C. A M. Fraga Eur. J. Med. Chem. 2011 46 1245 1253
- (2011) Eur. J. Med. Chem. , vol.46 , pp. 1245-1253
- Avila, C.M.¹ Lopes, A.B.² Goncalves, A.S.³ Da Silva, L.L.⁴ Romeiro, N.C.⁵ Miranda, A.L.P.⁶ Santanna, C.M.R.⁷ Barreiro, E.J.⁸ Fraga, M.⁹

51
- 84859224526
- Chinese Patent, ZL01008049
- Q. L. Guo. Q. D. You, F. Feng and W. Y. Liu, Chinese Patent, ZL01008049, 2003
- (2003)
- Guo, Q.L.¹ You, Q.D.² Feng, F.³ Liu, W.Y.⁴

52
- 20344405555
- Z. Q. Wu Q. L. Guo Q. D. You L. Zhao H. Y. Gu Biol. Pharm. Bull. 2004 27 1769 1774
- (2004) Biol. Pharm. Bull. , vol.27 , pp. 1769-1774
- Wu, Z.Q.¹ Guo, Q.L.² You, Q.D.³ Zhao, L.⁴ Gu, H.Y.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.