Cytochrome P450 monooxygenase-catalyzed ring opening of the bicyclic amine, nortropine: An experimental and DFT computational study

ChemCatChem

Volumn 4, Issue 4, 2012, Pages 530-539

  Kwiecień, Renata A ^a   Kosieradzka, Katarzyna ^a   Le Questel, Jean Yves ^a   Lebreton, Jacques ^a   Fournial, Anaïs ^a   Gentil, Emmanuel ^a   Delaforge, Marcel ^b   Paneth, Piotr ^c   Robins, Richard J ^a  

^a Centre National de la Recherche Scientifique   (France)

^b CEA   (France)

^c LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Computer chemistry; Enzymes; Isotope effects; Reaction mechanism; Ring opening

Indexed keywords

BACTERIA; CARBON; CARRIER MOBILITY; CATALYSIS; ENZYMES; ISOTOPES; NITROGEN; OXIDATION; PROTONATION; QUANTUM CHEMISTRY;

CARBON NITROGEN BONDS; COMPUTATIONAL STUDIES; COMPUTER CHEMISTRY; EXPERIMENTAL KINETICS; ISOTOPE EFFECT; QUANTUM CHEMISTRY CALCULATIONS; REACTION MECHANISM; RING OPENING;

CHEMICAL BONDS;

EID: 84859195018     PISSN: 18673880     EISSN: 18673899     Source Type: Journal    
DOI: 10.1002/cctc.201100386     Document Type: Article

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