2H, 13C, and 15N kinetic isotope effects on the reaction of the ammonia-rescued K258a mutant of aspartate aminotransferase

Biochemistry

Volumn 42, Issue 27, 2003, Pages 8369-8376

  Wright, S Kirk ^a   Rishavy, Mark A ^a,b   Cleland, W W ^a  

^a UNIVERSITY OF WISCONSIN   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; CATALYSIS; ESCHERICHIA COLI; ISOTOPES;

RATE-DETERMINING STEPS;

AMINO ACIDS;

ALANINE; AMMONIA; ASPARTATE AMINOTRANSFERASE; CARBON 13; DEUTERIUM; LYSINE; METHANOL DERIVATIVE; NITROGEN 15; ISOTOPE;

AMINO ACID SEQUENCE; ARTICLE; CALCULATION; CATALYSIS; ESCHERICHIA COLI; ISOTOPE ANALYSIS; MUTANT; MUTATION; PRIORITY JOURNAL; PROTON TRANSPORT; CHEMISTRY; GENETICS; KINETICS; METABOLISM;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

AMMONIA; ASPARTATE AMINOTRANSFERASES; ISOTOPES; KINETICS; MUTATION;

EID: 0037489352     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi030092f     Document Type: Article

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