Functional inclusion bodies produced in bacteria as naturally occurring nanopills for advanced cell therapies

Advanced Materials

Volumn 24, Issue 13, 2012, Pages 1742-1747

  Vázquez, Esther ^a,b   Corchero, José L ^a,b   Burgueño, Joan F ^a,c   Seras Franzoso, Joaquin ^a,b   Kosoy, Ana ^d   Bosser, Ramon ^d   Mendoza, Rosa ^a,b   Martínez Láinez, Joan Marc ^a,b   Rinas, Ursula ^e,f   Fernández, Ester ^a,c   Ruiz Avila, Luis ^d   García Fruitõs, Elena ^a,b   Villaverde, Antonio ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d Janus Development SL   (Spain)

^e LEIBNIZ UNIVERSITY HANNOVER   (Germany)

^f HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

cell therapy; nanomedicine; nanopills; protein particles; recombinant proteins

Indexed keywords

CELL THERAPY; DIVERSE STRESS; FUNCTIONAL PROTEINS; INCLUSION BODIES; MAMMALIAN CELLS; NANOPILLS; NATURALLY OCCURRING; PROTEIN PARTICLES; RECOMBINANT BACTERIA; SUSTAINED DRUG RELEASE; THERAPEUTIC POTENTIALS;

BACTERIA; MEDICAL NANOTECHNOLOGY; RECOMBINANT PROTEINS;

MOLECULAR BIOLOGY;

CATALASE; DIHYDROFOLATE REDUCTASE; GREEN FLUORESCENT PROTEIN; HEAT SHOCK PROTEIN 70; LEUKEMIA INHIBITORY FACTOR; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; CELL INCLUSION; CELL LINE; CELL MEMBRANE PERMEABILITY; DELAYED RELEASE FORMULATION; ESCHERICHIA COLI; HELA CELL; HUMAN; METABOLISM; MOUSE;

ANIMALS; CATALASE; CELL LINE; CELL MEMBRANE PERMEABILITY; DELAYED-ACTION PREPARATIONS; ESCHERICHIA COLI; GREEN FLUORESCENT PROTEINS; HELA CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INCLUSION BODIES; LEUKEMIA INHIBITORY FACTOR; MICE; RECOMBINANT PROTEINS; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84859154388     PISSN: 09359648     EISSN: 15214095     Source Type: Journal    
DOI: 10.1002/adma.201104330     Document Type: Article

References (63)

1. A. Villaverde, M. M. Carrio, Biotechnol. Lett. 2003, 25, 1385.
2. M. Morell, R. Bravo, A. Espargaro, X. Sisquella, F. X. Aviles, X. Fernandez-Busquets, S. Ventura, Biochim. Biophys. Acta 2008, 1783, 1815.
3. S. Peternel, R. Komel, Int. J. Mol. Sci. 2011, 12, 8275.
4. G. A. Bowden, A. M. Paredes, G. Georgiou, Biotechnology 1991, 9, 725.
5. C. Diez-Gil, S. Krabbenborg, E. Garcia-Fruitos, E. Vazquez, E. Rodriguez-Carmona, I. Ratera, N. Ventosa, J. Seras-Franzoso, O. Cano-Garrido, N. Ferrer-Miralles, A. Villaverde, J. Veciana, Biomaterials 2010, 31, 5805.
6. J. Seras-Franzoso, C. Diez-Gil, E. Vazquez, E. Garcia-Fruitos, R. Cubarsi, I. Ratera, J. Veciana, A. Villaverde, Nanomedicine 2012, 7, 79.
7. E. García-Fruitõs, E. Rodríguez-Carmona, C. Díez-Gil, R. M. Ferraz, E. Vázquez, J. L. Corchero, M. Cano-Sarabia, I. Ratera, N. Ventosa, J. Veciana, A. Villaverde, Adv. Mater. 2009, 21, 4249.
8. E. Rodriguez-Carmona, O. Cano-Garrido, J. Seras-Franzoso, A. Villaverde, E. Garcia-Fruitos, Microb. Cell Fact. 2010, 9, 71.
9. G. Georgiou, P. Valax, Methods Enzymol. 1999, 309, 48.
10. F. Baneyx, M. Mujacic, Nat. Biotechnol. 2004, 22, 1399.
11. A. Jungbauer, W. Kaar, J. Biotechnol. 2007, 128, 587.
12. S. M. Singh, A. K. Panda, J. Biosci. Bioeng. 2005, 99, 303.
13. L. F. Vallejo, U. Rinas, Microb. Cell Fact. 2004, 3, 11.
14. L. D. Cabrita, S. P. Bottomley, Biotechnol. Annu. Rev. 2004, 10, 31.
15. E. Garcia-Fruitos, J. Seras-Franzoso, E. Vazquez, A. Villaverde, Nanotechnology 2010, 21, 205101.
16. S. Peternel, S. Jevsevar, M. Bele, V. Gaberc-Porekar, V. Menart, Biotechnol. Appl. Biochem. 2008, 49, 239.
17. W. Wu, L. Xing, B. Zhou, Z. Lin, Microb. Cell Fact. 2011, 10, 9.
18. J. Nahalka, B. Nidetzky, Biotechnol. Bioeng. 2007, 97, 454.
19. S. Ventura, A. Villaverde, Trends Biotechnol. 2006, 24, 179.
20. E. Garcia-Fruitos, A. Villaverde, Korean J. Chem. Eng. 2010, 27, 385.
21. E. Garcia-Fruitos, N. Gonzalez-Montalban, M. Morell, A. Vera, R. M. Ferraz, A. Aris, S. Ventura, A. Villaverde, Microb. Cell Fact. 2005, 4, 27.
22. E. Garcia-Fruitos, M. Martinez-Alonso, N. Gonzalez-Montalban, M. Valli, D. Mattanovich, A. Villaverde, J. Mol. Biol. 2007, 374, 195.
23. A. Vera, N. Gonzalez-Montalban, A. Aris, A. Villaverde, Biotechnol. Bioeng. 2007, 96, 1101.
24. S. Peternel, J. Grdadolnik, V. Gaberc-Porekar, R. Komel, Microbiol. Cell Fact. 2008, 7, 34.
25. N. Gonzalez-Montalban, E. Garcia-Fruitos, A. Villaverde, Nat. Biotechnol. 2007, 25, 718.
26. E. Garcia-Fruitos, A. Aris, A. Villaverde, Appl. Environ. Microbiol. 2007, 73, 289.
27. E. Garcia-Fruitos, E. Vazquez, C. Diez-Gil, J. L. Corchero, J. Seras-Franzoso, I. Ratera, J. Veciana, A. Villaverde, Trends Biotechnol 2012, 30, 65.
28. D. Shcherbo, E. M. Merzlyak, T. V. Chepurnykh, A. F. Fradkov, G. V. Ermakova, E. A. Solovieva, K. A. Lukyanov, E. A. Bogdanova, A. G. Zaraisky, S. Lukyanov, D. M. Chudakov, Nat. Methods 2007, 4, 741.
29. J. P. Richard, K. Melikov, E. Vives, C. Ramos, B. Verbeure, M. J. Gait, L. V. Chernomordik, B. Lebleu, J. Biol. Chem. 2003, 278, 585.
30. S. K. Calderwood, J. R. Theriault, J. Gong, Eur. J. Immunol. 2005, 35, 2518.
31. J. Guo, H. Xin,. Science 2006, 314, 1232.
32. C. Garrido, E. Schmitt, C. Cande, N. Vahsen, A. Parcellier, G. Kroemer, Cell Cycle 2003, 2, 579.
33. C. Garrido, S. Gurbuxani, L. Ravagnan, G. Kroemer, Biochem. Biophys. Res. Commun. 2001, 286, 433.
34. D. Lanneau, M. Brunet, E. Frisan, E. Solary, M. Fontenay, C. Garrido, J. Cell Mol. Med. 2008, 12, 743.
35. T. Sugiyama, B. D. Levy, T. Michel, J. Biol. Chem. 2009, 284, 12691.
36. J. R. Schnell, H. J. Dyson, P. E. Wright, Annu. Rev. Biophys. Biomol. Struct. 2004, 33, 119.
37. H. Cario, D. E. Smith, H. Blom, N. Blau, H. Bode, K. Holzmann, U. Pannicke, K. P. Hopfner, E. M. Rump, Z. Ayric, E. Kohne, K. M. Debatin, Y. Smulders, K. Schwarz, Am. J. Hum. Genet. 2011, 88, 226.
38. B. S. Askari, M. Krajinovic, Curr. Genomics 2010, 11, 578.
39. H. Lodish, A. Berk, S. L. Zipursky, P. Matsudaira, D. Baltimore, J. Darnell, Molecular Cell Biology, 4th edition, W. H. Freeman and Company, New York, USA 2011.
40. L. Packer, E. Cadenas,. Free Radic. Res. 2007, 41, 951.
41. J. Goh, L. Enns, S. Fatemie, H. Hopkins, J. Morton, C. Pettan-Brewer, W. Ladiges, BMC Cancer 2011, 11, 191.
42. X. L. Shi, Z. H. Shi, H. Huang, H. G. Zhu, P. Zhou, D. Ju, Inflammation 2010, 33, 166.
43. B. Beltran, P. Nos, F. Dasi, M. Iborra, G. Bastida, M. Martinez, J. E. O'Connor, G. Saez, I. Moret, J. Ponce, Inflamm. Bowel. Dis. 2010, 16, 76.
44. H. J. Geuze, J. W. Slot, P. A. van der Ley, R. C. Scheffer, J. Cell Biol. 1981, 89, 653.
45. G. Skiniotis, P. J. Lupardus, M. Martick, T. Walz, K. C. Garcia, Mol. Cell 2008, 31, 737.
46. R. C. Robinson, L. M. Grey, D. Staunton, H. Vankelecom, A. B. Vernallis, J. F. Moreau, D. I. Stuart, J. K. Heath, E. Y. Jones, Cell 1994, 77, 1101.
47. C. L. Stewart, P. Kaspar, L. J. Brunet, H. Bhatt, I. Gadi, F. Kontgen, S. J. Abbondanzo, Nature 1992, 359, 76.
48. W. Hu, Z. Feng, A. K. Teresky, A. J. Levine, Nature 2007, 450, 721.
49. S. Imsoonthornruksa, P. Noisa, R. Parnpai, M. Ketudat-Cairns, J. Biotechnol. 2011, 151, 295.
50. U. Rinas, J. E. Bailey, Appl. Microbiol. Biotechnol. 1992, 37, 609.
51. M. M. Carrio, A. Villaverde, J. Bacteriol. 2005, 187, 3599.
52. N. Ferrer-Miralles, J. Domingo-Espin, J. L. Corchero, E. Vazquez, A. Villaverde, Microb. Cell Fact. 2009, 8, 17.
53. P. Neubauer, B. Fahnert, H. Lilie, A. Villaverde, in Inclusions in Prokaryotes, (Ed:, J. M. Shively,), Springer, Germany pp. 237, 2006.
54. S. Peternel, R. Komel, Microb. Cell Fact. 2010, 9, 66.
55. Z. Antosova, M. Mackova, V. Kral, T. Macek, Trends Biotechnol. 2009, 27, 628.
56. J. H. Meyer, in Physiology of the gastrointestinal tract, (Ed:, L. R. Johnson LR,). Raven Press, New York, USA, pp. 613, 1987.
57. Y. Miyabara, M. Tabata, J. Suzuki, S. Suzuki, J. Chromatogr. 1992, 574, 261.
58. A. Mitraki, Adv. Protein Chem. Struct. Biol. 2010, 79, 89.
59. E. Garcia-Fruitos, Microb. Cell Fact. 2010, 9, 80.
60. A. Villaverde, Microb. Cell Fact. 2010, 9, 53.
61. E. Rodriguez-Carmona, A. Villaverde, Trends Microbiol. 2010, 18, 423.
62. E. Vazquez, A. Villaverde, Microb. Cell Fact. 2010, 9, 101.
63. L. F. Vallejo, M. Brokelmann, S. Marten, S. Trappe, J. Cabrera-Crespo, A. Hoffmann, G. Gross, H. A. Weich, U. Rinas, J. Biotechnol. 2002, 94, 185.