-
1
-
-
0021319887
-
The functional human dihydrofolate reductase gene
-
Chen, M.J.; Shimada, T.; Moulton, A.D.; Cline, A.; Humphries, R.K.; Maizel, J.; Nienhuis, A.W. The functional human dihydrofolate reductase gene. J. Biol. Chem., 1984, 259(6), 3933-3943.
-
(1984)
J. Biol. Chem
, vol.259
, Issue.6
, pp. 3933-3943
-
-
Chen, M.J.1
Shimada, T.2
Moulton, A.D.3
Cline, A.4
Humphries, R.K.5
Maizel, J.6
Nienhuis, A.W.7
-
2
-
-
0030931381
-
Distinct roles for Sp1 and E2F sites in the growth/cell cycle regulation of the DHFR promoter
-
Jensen, D.E.; Black, A.R.; Swick, A.G.; Azizkhan, J.C. Distinct roles for Sp1 and E2F sites in the growth/cell cycle regulation of the DHFR promoter. J. Cell. Biochem., 1997, 67(1), 24-31.
-
(1997)
J. Cell. Biochem
, vol.67
, Issue.1
, pp. 24-31
-
-
Jensen, D.E.1
Black, A.R.2
Swick, A.G.3
Azizkhan, J.C.4
-
3
-
-
0037215382
-
The 5'-untranslated RNA of the human dhfr minor transcript alters transcription pre-initiation complex assembly at the major (core) promoter
-
Blume, S.W.; Meng, Z.; Shrestha, K.; Snyder, R.C.; Emanuel, P.D. The 5'-untranslated RNA of the human dhfr minor transcript alters transcription pre-initiation complex assembly at the major (core) promoter. J. Cell. Biochem., 2003, 88(1), 165-180.
-
(2003)
J. Cell. Biochem
, vol.88
, Issue.1
, pp. 165-180
-
-
Blume, S.W.1
Meng, Z.2
Shrestha, K.3
Snyder, R.C.4
Emanuel, P.D.5
-
4
-
-
33846930357
-
Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript
-
Martianov, I.; Ramadass, A.; Serra Barros, A.; Chow, N.; Akoulitchev, A. Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript. Nature, 2007, 445(7128), 666-670.
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 666-670
-
-
Martianov, I.1
Ramadass, A.2
Serra, B.A.3
Chow, N.4
Akoulitchev, A.5
-
5
-
-
63449123250
-
The methylenetetrahydrofolate reductase C677T mutation induces cellspecific changes in genomic DNA methylation and uracil misincorporation: A possible molecular basis for the site-specific cancer risk modification
-
Sohn, K.J.; Jang, H.; Campan, M.; Weisenberger, D.J.; Dickhout, J.; Wang, Y.C.; Cho, R.C.; Yates, Z.; Lucock, M.; Chiang, E.P.; Austin, R.C.; Choi, S.W.; Laird, P.W.; Kim, Y.I. The methylenetetrahydrofolate reductase C677T mutation induces cellspecific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification. Int. J. Cancer, 2009, 124(9), 1999-2005.
-
(2009)
Int. J. Cancer
, vol.124
, Issue.9
, pp. 1999-2005
-
-
Sohn, K.J.1
Jang, H.2
Campan, M.3
Weisenberger, D.J.4
Dickhout, J.5
Wang, Y.C.6
Cho, R.C.7
Yates, Z.8
Lucock, M.9
Chiang, E.P.10
Austin, R.C.11
Choi, S.W.12
Laird, P.W.13
Kim, Y.I.14
-
6
-
-
33947375647
-
Molecular basis of antifolate resistance
-
Assaraf, Y.G. Molecular basis of antifolate resistance. Cancer Metastasis Rev., 2007, 26(1), 153-181.
-
(2007)
Cancer Metastasis Rev
, vol.26
, Issue.1
, pp. 153-181
-
-
Assaraf, Y.G.1
-
7
-
-
0021740106
-
Structure-Activity Relationships of Dihydrofolate Reductase Inhibitors
-
Blaney, J.; Hansch, C.; Silipo, C.; Vittoria, A. Structure-Activity Relationships of Dihydrofolate Reductase Inhibitors. Chem. Rev., 1984, 84(4), 333-407.
-
(1984)
Chem. Rev
, vol.84
, Issue.4
, pp. 333-407
-
-
Blaney, J.1
Hansch, C.2
Silipo, C.3
Vittoria, A.4
-
8
-
-
60849083812
-
Dihydrofolate reductase amplification and sensitization to methotrexate of methotrexate-resistant colon cancer cells
-
Morales, C.; Garcia, M.J.; Ribas, M.; Miro, R.; Munoz, M.; Caldas, C.; Peinado, M.A. Dihydrofolate reductase amplification and sensitization to methotrexate of methotrexate-resistant colon cancer cells. Mol. Cancer Ther., 2009, 8(2), 424-432.
-
(2009)
Mol. Cancer Ther
, vol.8
, Issue.2
, pp. 424-432
-
-
Morales, C.1
Garcia, M.J.2
Ribas, M.3
Miro, R.4
Munoz, M.5
Caldas, C.6
Peinado, M.A.7
-
9
-
-
0029846176
-
Intrinsic and acquired resistance to methotrexate in acute leukemia
-
Gorlick, R.; Goker, E.; Trippett, T.; Waltham, M.; Banerjee, D.; Bertino, J.R. Intrinsic and acquired resistance to methotrexate in acute leukemia. N. Engl. J. Med., 1996, 335(14), 1041-1048.
-
(1996)
N. Engl. J. Med
, vol.335
, Issue.14
, pp. 1041-1048
-
-
Gorlick, R.1
Goker, E.2
Trippett, T.3
Waltham, M.4
Banerjee, D.5
Bertino, J.R.6
-
10
-
-
0021216769
-
Chromosomal organization of the human dihydrofolate reductase genes: Dispersion, selective amplification, and a novel form of polymorphism
-
Anagnou, N.P.; O'Brien, S.J.; Shimada, T.; Nash, W.G.; Chen, M.J.; Nienhuis, A.W. Chromosomal organization of the human dihydrofolate reductase genes: dispersion, selective amplification, and a novel form of polymorphism. Proc. Natl. Acad. Sci. USA, 1984, 81(16), 5170-5174.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, Issue.16
, pp. 5170-5174
-
-
Anagnou, N.P.1
O'Brien, S.J.2
Shimada, T.3
Nash, W.G.4
Chen, M.J.5
Nienhuis, A.W.6
-
11
-
-
0020321141
-
Multiple forms of human dihydrofolate reductase messenger RNA. Cloning and expression in Escherichia coli of their DNA coding sequence
-
Morandi, C.; Masters, J.N.; Mottes, M.; Attardi, G. Multiple forms of human dihydrofolate reductase messenger RNA. Cloning and expression in Escherichia coli of their DNA coding sequence. J. Mol. Biol., 1982, 156(3), 583-607.
-
(1982)
J. Mol. Biol
, vol.156
, Issue.3
, pp. 583-607
-
-
Morandi, C.1
Masters, J.N.2
Mottes, M.3
Attardi, G.4
-
12
-
-
21744443422
-
Preventing neural tube defects in Europe: A missed opportunity
-
Busby, A.; Abramsky, L.; Dolk, H.; Armstrong, B.; Addor, M.C.; Anneren, G.; Armstrong, N.; Baguette, A.; Barisic, I.; Berghold, A.; Bianca, S.; Braz, P.; Calzolari, E.; Christiansen, M.; Cocchi, G.; Daltveit, A.K.; De Walle, H.; Edwards, G.; Gatt, M.; Gener, B.; Gillerot, Y.; Gjergja, R.; Goujard, J.; Haeusler, M.; Latos-Bielenska, A.; McDonnell, R.; Neville, A.; Olars, B.; Portillo, I.; Ritvanen, A.; Robert-Gnansia, E.; Rösch, C.; Scarano, G.; Steinbicker, V. Preventing neural tube defects in Europe: a missed opportunity. Reprod. Toxicol., 2005, 20(3), 393-402.
-
(2005)
Reprod. Toxicol
, vol.20
, Issue.3
, pp. 393-402
-
-
Busby, A.1
Abramsky, L.2
Dolk, H.3
Armstrong, B.4
Addor, M.C.5
Anneren, G.6
Armstrong, N.7
Baguette, A.8
Barisic, I.9
Berghold, A.10
Bianca, S.11
Braz, P.12
Calzolari, E.13
Christiansen, M.14
Cocchi, G.15
Daltveit, A.K.16
de Walle, H.17
Edwards, G.18
Gatt, M.19
Gener, B.20
Gillerot, Y.21
Gjergja, R.22
Goujard, J.23
Haeusler, M.24
Latos-Bielenska, A.25
McDonnell, R.26
Neville, A.27
Olars, B.28
Portillo, I.29
Ritvanen, A.30
Robert-Gnansia, E.31
Rösch, C.32
Scarano, G.33
Steinbicker, V.34
more..
-
13
-
-
34249903333
-
The 19-bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population
-
Parle-McDermott, A.; Pangilinan, F.; Mills, J.L.; Kirke, P.N.; Gibney, E.R.; Troendle, J.; O'Leary, V.B.; Molloy, A.M.; Conley, M.; Scott, J.M.; Brody, L.C. The 19-bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population. Am. J. Med. Genet. A., 2007, 143A(11), 1174-1180.
-
(2007)
Am. J. Med. Genet. A
, vol.143 A
, Issue.11
, pp. 1174-1180
-
-
Parle-McDermott, A.1
Pangilinan, F.2
Mills, J.L.3
Kirke, P.N.4
Gibney, E.R.5
Troendle, J.6
O'Leary, V.B.7
Molloy, A.M.8
Conley, M.9
Scott, J.M.10
Brody, L.C.11
-
14
-
-
41149145923
-
An insertion/deletion polymorphism of the dihydrofolate reductase (DHFR) gene is associated with serum and red blood cell folate concentrations in women
-
Stanislawska-Sachadyn, A.; Brown, K. S.; Mitchell, L. E.; Woodside, J. V.; Young, I. S.; Scott, J. M.; Murray, L.; Boreham, C. A.; McNulty, H.; Strain, J. J.; Whitehead, A. S. An insertion/deletion polymorphism of the dihydrofolate reductase (DHFR) gene is associated with serum and red blood cell folate concentrations in women. Hum. Genet., 2008, 123(3), 289-95.
-
(2008)
Hum. Genet
, vol.123
, Issue.3
, pp. 289-295
-
-
Stanislawska-Sachadyn, A.1
Brown, K.S.2
Mitchell, L.E.3
Woodside, J.V.4
Young, I.S.5
Scott, J.M.6
Murray, L.7
Boreham, C.A.8
McNulty, H.9
Strain, J.J.10
Whitehead, A.S.11
-
15
-
-
0034190659
-
5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: A HuGE review
-
Botto, L.D.; Yang, Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am. J. Epidemiol., 2000, 151(9), 862-877.
-
(2000)
Am. J. Epidemiol
, vol.151
, Issue.9
, pp. 862-877
-
-
Botto, L.D.1
Yang, Q.2
-
16
-
-
0033547432
-
Neuraltube defects
-
Botto, L.D.; Moore, C.A.; Khoury, M.J.; Erickson, J.D. Neuraltube defects. N. Engl. J. Med., 1999, 341(20), 1509-1519.
-
(1999)
N. Engl. J. Med
, vol.341
, Issue.20
, pp. 1509-1519
-
-
Botto, L.D.1
Moore, C.A.2
Khoury, M.J.3
Erickson, J.D.4
-
17
-
-
0942290719
-
New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy
-
Johnson, W.G.; Stenroos, E.S.; Spychala, J.R.; Chatkupt, S.; Ming, S.X.; Buyske, S. New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): a risk factor for spina bifida acting in mothers during pregnancy? Am. J. Med. Genet., 2004, 124A(4), 339-345.
-
(2004)
Am. J. Med. Genet
, vol.124 A
, Issue.4
, pp. 339-345
-
-
Johnson, W.G.1
Stenroos, E.S.2
Spychala, J.R.3
Chatkupt, S.4
Ming, S.X.5
Buyske, S.6
-
18
-
-
15744388471
-
Common dihydrofolate reductase 19-base pair deletion allele: A novel risk factor for preterm delivery
-
Johnson, W.G.; Scholl, T.O.; Spychala, J.R.; Buyske, S.; Stenroos, E.S.; Chen, X. Common dihydrofolate reductase 19-base pair deletion allele: a novel risk factor for preterm delivery. Am. J. Clin. Nutr., 2005, 81(3), 664-668.
-
(2005)
Am. J. Clin. Nutr
, vol.81
, Issue.3
, pp. 664-668
-
-
Johnson, W.G.1
Scholl, T.O.2
Spychala, J.R.3
Buyske, S.4
Stenroos, E.S.5
Chen, X.6
-
19
-
-
34047248403
-
Variation and expression of dihydrofolate reductase (DHFR) in relation to spina bifida
-
van der Linden, I.J.; Nguyen, U.; Heil, S.G.; Franke, B.; Vloet, S.; Gellekink, H.; den Heijer, M.; Blom, H.J. Variation and expression of dihydrofolate reductase (DHFR) in relation to spina bifida. Mol. Genet. Metab., 2007, 91(1), 98-103.
-
(2007)
Mol. Genet. Metab
, vol.91
, Issue.1
, pp. 98-103
-
-
van der Linden, I.J.1
Nguyen, U.2
Heil, S.G.3
Franke, B.4
Vloet, S.5
Gellekink, H.6
den Heijer, M.7
Blom, H.J.8
-
20
-
-
33845531853
-
Molecular genetic analysis of the human dihydrofolate reductase gene: Relation with plasma total homocysteine, serum and red blood cell folate levels
-
Gellekink, H.; Blom, H.J.; van der Linden, I.J.; den Heijer, M. Molecular genetic analysis of the human dihydrofolate reductase gene: relation with plasma total homocysteine, serum and red blood cell folate levels. Eur. J. Hum. Genet., 2007, 15(1), 103-109.
-
(2007)
Eur. J. Hum. Genet
, vol.15
, Issue.1
, pp. 103-109
-
-
Gellekink, H.1
Blom, H.J.2
van der Linden, I.J.3
den Heijer, M.4
-
21
-
-
34147122502
-
A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin users
-
Xu, X.; Gammon, M.D.; Wetmur, J.G.; Rao, M.; Gaudet, M.M.; Teitelbaum, S.L.; Britton, J.A.; Neugut, A.I.; Santella, R.M.; Chen, J. A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin users. Am. J. Clin. Nutr., 2007, 85(4), 1098-1102.
-
(2007)
Am. J. Clin. Nutr
, vol.85
, Issue.4
, pp. 1098-1102
-
-
Xu, X.1
Gammon, M.D.2
Wetmur, J.G.3
Rao, M.4
Gaudet, M.M.5
Teitelbaum, S.L.6
Britton, J.A.7
Neugut, A.I.8
Santella, R.M.9
Chen, J.10
-
22
-
-
57349115474
-
19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate
-
Kalmbach, R.D.; Choumenkovitch, S.F.; Troen, A.P.; Jacques, P.F.; D'Agostino, R.; Selhub, J. A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate. J. Nutr., 2008, 138(12), 2323-2327.
-
(2008)
J. Nutr
, vol.138
, Issue.12
, pp. 2323-2327
-
-
Kalmbach, R.D.1
Choumenkovitch, S.F.2
Troen, A.P.3
Jacques, P.F.4
D'Agostino, R.5
Selhub, J.A.6
-
23
-
-
43549120811
-
DNA variants in the dihydrofolate reductase gene and outcome in childhood ALL
-
Dulucq, S.; St-Onge, G.; Gagne, V.; Ansari, M.; Sinnett, D.; Labuda, D.; Moghrabi, A.; Krajinovic, M. DNA variants in the dihydrofolate reductase gene and outcome in childhood ALL. Blood, 2008, 111(7), 3692-3700.
-
(2008)
Blood
, vol.111
, Issue.7
, pp. 3692-3700
-
-
Dulucq, S.1
St-Onge, G.2
Gagne, V.3
Ansari, M.4
Sinnett, D.5
Labuda, D.6
Moghrabi, A.7
Krajinovic, M.8
-
24
-
-
72549086608
-
DNA variants in region for noncoding interfering transcript of dihydrofolate reductase gene and outcome in childhood acute lymphoblastic leukemia
-
Al-Shakfa, F.; Dulucq, S.; Brukner, I.; Milacic, I.; Ansari, M.; Beaulieu, P.; Moghrabi, A.; Laverdiere, C.; Sallan, S.E.; Silverman, L.B.; Neuberg, D.; Kutok, J.L.; Sinnett, D.; Krajinovic, M. DNA variants in region for noncoding interfering transcript of dihydrofolate reductase gene and outcome in childhood acute lymphoblastic leukemia. Clin. Cancer. Res., 2009, 15(22), 6931-6938.
-
(2009)
Clin. Cancer. Res
, vol.15
, Issue.22
, pp. 6931-6938
-
-
Al-Shakfa, F.1
Dulucq, S.2
Brukner, I.3
Milacic, I.4
Ansari, M.5
Beaulieu, P.6
Moghrabi, A.7
Laverdiere, C.8
Sallan, S.E.9
Silverman, L.B.10
Neuberg, D.11
Kutok, J.L.12
Sinnett, D.13
Krajinovic, M.14
-
25
-
-
31544467532
-
Nutritional epigenetics: Impact of folate deficiency on DNA methylation and colon cancer susceptibility
-
Kim, Y.I. Nutritional epigenetics: impact of folate deficiency on DNA methylation and colon cancer susceptibility. J. Nutr., 2005, 135(11), 2703-2709.
-
(2005)
J. Nutr
, vol.135
, Issue.11
, pp. 2703-2709
-
-
Kim, Y.I.1
-
26
-
-
67749111879
-
DHFR 19-bp insertion/deletion polymorphism and MTHFR C677T in adult acute lymphoblastic leukaemia: Is the risk reduction due to intracellular folate unbalancing
-
Gemmati, D.; De Mattei, M.; Catozzi, L.; Della Porta, M.; Serino, M.L.; Ambrosio, C.; Cuneo, A.; Friso, S.; Krampera, M.; Orioli, E.; Zeri, G.; Ongaro, A. DHFR 19-bp insertion/deletion polymorphism and MTHFR C677T in adult acute lymphoblastic leukaemia: is the risk reduction due to intracellular folate unbalancing? Am. J. Hematol., 2009, 84(8), 526-529.
-
(2009)
Am. J. Hematol
, vol.84
, Issue.8
, pp. 526-529
-
-
Gemmati, D.1
de Mattei, M.2
Catozzi, L.3
della Porta, M.4
Serino, M.L.5
Ambrosio, C.6
Cuneo, A.7
Friso, S.8
Krampera, M.9
Orioli, E.10
Zeri, G.11
Ongaro, A.12
-
27
-
-
0035552975
-
Polymorphisms in the methylenetetrahydrofolate reductase gene: Clinical consequences
-
Schwahn, B.; Rozen, R. Polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences. Am. J. Pharmacogenomics, 2001, 1(3), 189-201.
-
(2001)
Am. J. Pharmacogenomics
, vol.1
, Issue.3
, pp. 189-201
-
-
Schwahn, B.1
Rozen, R.2
-
28
-
-
0346966836
-
Role of MTHFR genetic polymorphisms in the susceptibility to childhood acutelymphoblastic leukemia
-
Krajinovic, M.; Lamothe, S.; Labuda, D.; Lemieux-Blanchard, E.; Theoret, Y.; Moghrabi, A.; Sinnett, D. Role of MTHFR genetic polymorphisms in the susceptibility to childhood acutelymphoblastic leukemia. Blood, 2004, 103(1), 252-257.
-
(2004)
Blood
, vol.103
, Issue.1
, pp. 252-257
-
-
Krajinovic, M.1
Lamothe, S.2
Labuda, D.3
Lemieux-Blanchard, E.4
Theoret, Y.5
Moghrabi, A.6
Sinnett, D.7
-
29
-
-
67349108801
-
Dihydrofolate reductase (DHRF) 19-bp intron-1 deletion and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms in breast cancer
-
Cam, R.; Eroglu, A.; Egin, Y.; Akar, N. Dihydrofolate reductase (DHRF) 19-bp intron-1 deletion and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms in breast cancer. Breast Cancer Res. Treat., 2009, 115(2), 431-432.
-
(2009)
Breast Cancer Res. Treat
, vol.115
, Issue.2
, pp. 431-432
-
-
Cam, R.1
Eroglu, A.2
Egin, Y.3
Akar, N.4
-
30
-
-
33646715354
-
Folate intake, alcohol use, and postmenopausal breast cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
-
Stolzenberg-Solomon, R.Z.; Chang, S.C.; Leitzmann, M.F.; Johnson, K.A.; Johnson, C.; Buys, S.S.; Hoover, R.N.; Ziegler, R.G. Folate intake, alcohol use, and postmenopausal breast cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Am. J. Clin. Nutr., 2006, 83(4), 895-904.
-
(2006)
Am. J. Clin. Nutr
, vol.83
, Issue.4
, pp. 895-904
-
-
Stolzenberg-Solomon, R.Z.1
Chang, S.C.2
Leitzmann, M.F.3
Johnson, K.A.4
Johnson, C.5
Buys, S.S.6
Hoover, R.N.7
Ziegler, R.G.8
-
31
-
-
77950690337
-
Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer
-
Hazra, A.; Fuchs, C.S.; Kawasaki, T.; Kirkner, G.J.; Hunter, D.J.; Ogino, S. Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer. Cancer Causes Control, 2010, 21(3), 331-345.
-
(2010)
Cancer Causes Control
, vol.21
, Issue.3
, pp. 331-345
-
-
Hazra, A.1
Fuchs, C.S.2
Kawasaki, T.3
Kirkner, G.J.4
Hunter, D.J.5
Ogino, S.6
-
32
-
-
34548178346
-
Genetic polymorphisms in one-carbon metabolism: Associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet
-
Curtin, K.; Slattery, M.L.; Ulrich, C.M.; Bigler, J.; Levin, T.R.; Wolff, R.K.; Albertsen, H.; Potter, J.D.; Samowitz, W.S. Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet. Carcinogenesis, 2007, 28(8), 1672-1679.
-
(2007)
Carcinogenesis
, vol.28
, Issue.8
, pp. 1672-1679
-
-
Curtin, K.1
Slattery, M.L.2
Ulrich, C.M.3
Bigler, J.4
Levin, T.R.5
Wolff, R.K.6
Albertsen, H.7
Potter, J.D.8
Samowitz, W.S.9
-
33
-
-
77954469742
-
A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk
-
Levine, A.J.; Figueiredo, J.C.; Lee, W.; Conti, D.V.; Kennedy, K.; Duggan, D.J.; Poynter, J.N.; Campbell, P.T.; Newcomb, P.; Martinez, M.E.; Hopper, J.L.; Le Marchand, L.; Baron, J.A.; Limburg, P.J.; Ulrich, C.M.; Haile, R.W. A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer Epidemiol. Biomarkers Prev., 2010, 19(7), 1812-1821.
-
(2010)
Cancer Epidemiol. Biomarkers Prev
, vol.19
, Issue.7
, pp. 1812-1821
-
-
Levine, A.J.1
Figueiredo, J.C.2
Lee, W.3
Conti, D.V.4
Kennedy, K.5
Duggan, D.J.6
Poynter, J.N.7
Campbell, P.T.8
Newcomb, P.9
Martinez, M.E.10
Hopper, J.L.11
Le Marchand, L.12
Baron, J.A.13
Limburg, P.J.14
Ulrich, C.M.15
Haile, R.W.16
-
34
-
-
34548137731
-
Pharmacogenomics of acute leukemia
-
Ansari, M.; Krajinovic, M. Pharmacogenomics of acute leukemia. Pharmacogenomics, 2007, 8(7), 817-834.
-
(2007)
Pharmacogenomics
, vol.8
, Issue.7
, pp. 817-834
-
-
Ansari, M.1
Krajinovic, M.2
-
35
-
-
0037130286
-
Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase
-
Banerjee, D.; Mayer-Kuckuk, P.; Capiaux, G.; Budak-Alpdogan, T.; Gorlick, R.; Bertino, J.R. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase. Biochim. Biophys. Acta, 2002, 1587(2-3), 164-173.
-
(2002)
Biochim. Biophys. Acta
, vol.1587
, Issue.2-3
, pp. 164-173
-
-
Banerjee, D.1
Mayer-Kuckuk, P.2
Capiaux, G.3
Budak-Alpdogan, T.4
Gorlick, R.5
Bertino, J.R.6
-
36
-
-
0028909195
-
Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia
-
Matherly, L.H.; Taub, J.W.; Ravindranath, Y.; Proefke, S.A.; Wong, S.C.; Gimotty, P.; Buck, S.; Wright, J.E.; Rosowsky, A. Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia. Blood, 1995, 85, 500-509.
-
(1995)
Blood
, vol.85
, pp. 500-509
-
-
Matherly, L.H.1
Taub, J.W.2
Ravindranath, Y.3
Proefke, S.A.4
Wong, S.C.5
Gimotty, P.6
Buck, S.7
Wright, J.E.8
Rosowsky, A.9
-
37
-
-
9144254448
-
Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells
-
Serra, M.; Reverter-Branchat, G.; Maurici, D.; Benini, S.; Shen, J.N.; Chano, T.; Hattinger, C.M.; Manara, M.C.; Pasello, M.; Scotlandi, K.; Picci, P. Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells. Ann. Oncol., 2004, 15(1), 151-160.
-
(2004)
Ann. Oncol
, vol.15
, Issue.1
, pp. 151-160
-
-
Serra, M.1
Reverter-Branchat, G.2
Maurici, D.3
Benini, S.4
Shen, J.N.5
Chano, T.6
Hattinger, C.M.7
Manara, M.C.8
Pasello, M.9
Scotlandi, K.10
Picci, P.11
-
38
-
-
0029075026
-
Amplification of the dihydrofolate reductase gene is a mechanism of acquired resistance to methotrexate in patients with acute lymphoblastic leukemia and is correlated with p53 gene mutations
-
Goker, E.; Waltham, M.; Kheradpour, A.; Trippett, T.; Mazumdar, M.; Elisseyeff, Y.; Schnieders, B.; Steinherz, P.; Tan, C.; Berman, E., et al. Amplification of the dihydrofolate reductase gene is a mechanism of acquired resistance to methotrexate in patients with acute lymphoblastic leukemia and is correlated with p53 gene mutations. Blood, 1995, 86(2), 677-684.
-
(1995)
Blood
, vol.86
, Issue.2
, pp. 677-684
-
-
Goker, E.1
Waltham, M.2
Kheradpour, A.3
Trippett, T.4
Mazumdar, M.5
Elisseyeff, Y.6
Schnieders, B.7
Steinherz, P.8
Tan, C.9
Berman, E.10
-
39
-
-
0034771885
-
A novel single-nucleotide polymorphism in the 3'- untranslated region of the human dihydrofolate reductase gene with enhanced expression
-
Goto, Y.; Yue, L.; Yokoi, A.; Nishimura, R.; Uehara, T.; Koizumi, S.; Saikawa, Y. A novel single-nucleotide polymorphism in the 3'- untranslated region of the human dihydrofolate reductase gene with enhanced expression. Clin. Cancer Res., 2001, 7(7), 1952-1956.
-
(2001)
Clin. Cancer Res
, vol.7
, Issue.7
, pp. 1952-1956
-
-
Goto, Y.1
Yue, L.2
Yokoi, A.3
Nishimura, R.4
Uehara, T.5
Koizumi, S.6
Saikawa, Y.7
-
40
-
-
34548059198
-
A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance
-
Mishra, P.J.; Humeniuk, R.; Mishra, P.J.; Longo-Sorbello, G.S.; Banerjee, D.; Bertino, J.R. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc. Natl. Acad. Sci. USA, 2007, 104(33), 13513-13518.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.33
, pp. 13513-13518
-
-
Mishra, P.J.1
Humeniuk, R.2
Mishra, P.J.3
Longo-Sorbello, G.S.4
Banerjee, D.5
Bertino, J.R.6
-
41
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros, V. The functions of animal microRNAs. Nature, 2004, 431(7006), 350-355.
-
(2004)
Nature
, vol.431
, Issue.7006
, pp. 350-355
-
-
Ambros, V.1
-
42
-
-
67650711156
-
MicroRNAs in Cancer
-
Garzon, R.; Calin, G.A.; Croce, C.M. MicroRNAs in Cancer. Annu. Rev. Med., 2009, 60, 167-179.
-
(2009)
Annu. Rev. Med
, vol.60
, pp. 167-179
-
-
Garzon, R.1
Calin, G.A.2
Croce, C.M.3
-
43
-
-
20444467290
-
A microRNA polycistron as a potential human oncogene
-
He, L.; Thomson, J.M.; Hemann, M.T.; Hernando-Monge, E.; Mu, D.; Goodson, S.; Powers, S.; Cordon-Cardo, C.; Lowe, S.W.; Hannon, G.J.; Hammond, S.M. A microRNA polycistron as a potential human oncogene. Nature, 2005, 435(7043), 828-833.
-
(2005)
Nature
, vol.435
, Issue.7043
, pp. 828-833
-
-
He, L.1
Thomson, J.M.2
Hemann, M.T.3
Hernando-Monge, E.4
Mu, D.5
Goodson, S.6
Powers, S.7
Cordon-Cardo, C.8
Lowe, S.W.9
Hannon, G.J.10
Hammond, S.M.11
-
44
-
-
77951597361
-
Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells
-
Song, B.; Wang, Y.; Titmus, M.A.; Botchkina, G.; Formentini, A.; Kornmann, M.; Ju, J. Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells. Mol. Cancer, 2010, 9, 96.
-
(2010)
Mol. Cancer
, vol.9
, pp. 96
-
-
Song, B.1
Wang, Y.2
Titmus, M.A.3
Botchkina, G.4
Formentini, A.5
Kornmann, M.6
Ju, J.7
-
45
-
-
42449110323
-
MiRSNPs or MiRpolymorphisms, new players in microRNA mediated regulation of the cell: Introducing microRNA pharmacogenomics
-
Mishra, P.J.; Banerjee, D.; Bertino, J.R. MiRSNPs or MiRpolymorphisms, new players in microRNA mediated regulation of the cell: Introducing microRNA pharmacogenomics. Cell Cycle, 2008, 7(7), 853-858.
-
(2008)
Cell Cycle
, vol.7
, Issue.7
, pp. 853-858
-
-
Mishra, P.J.1
Banerjee, D.2
Bertino, J.R.3
-
46
-
-
65649138698
-
MicroRNA polymorphisms: The future of pharmacogenomics, molecular epidemiology and individualized medicine
-
Mishra, P.J.; Bertino, J.R. MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. Pharmacogenomics, 2009, 10(3), 399-416.
-
(2009)
Pharmacogenomics
, vol.10
, Issue.3
, pp. 399-416
-
-
Mishra, P.J.1
Bertino, J.R.2
-
47
-
-
0024328152
-
Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene
-
Fujii, H.; Shimada, T. Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene. J. Biol. Chem., 1989, 264(17), 10057-10064.
-
(1989)
J. Biol. Chem
, vol.264
, Issue.17
, pp. 10057-10064
-
-
Fujii, H.1
Shimada, T.2
-
48
-
-
0029564716
-
Nine-bp repeat polymorphism in exon 1 of the hMSH3 gene
-
Nakajima, E.; Orimo, H.; Ikejima, M.; Shimada, T. Nine-bp repeat polymorphism in exon 1 of the hMSH3 gene. Jpn. J. Hum. Genet., 1995, 40(4), 343-345.
-
(1995)
Jpn. J. Hum. Genet
, vol.40
, Issue.4
, pp. 343-345
-
-
Nakajima, E.1
Orimo, H.2
Ikejima, M.3
Shimada, T.4
-
49
-
-
30344465333
-
Genetics of rheumatoid arthritis
-
Turesson, C.; Matteson, E.L. Genetics of rheumatoid arthritis. Mayo Clin. Proc., 2006, 81(1), 94-101.
-
(2006)
Mayo Clin. Proc
, vol.81
, Issue.1
, pp. 94-101
-
-
Turesson, C.1
Matteson, E.L.2
-
50
-
-
33646354882
-
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes
-
Wessels, J.A.; de Vries-Bouwstra, J.K.; Heijmans, B.T.; Slagboom, P.E.; Goekoop-Ruiterman, Y.P.; Allaart, C.F.; Kerstens, P.J.; van Zeben, D.; Breedveld, F.C.; Dijkmans, B.A.; Huizinga, T.W.; Guchelaar, H.J. Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes. Arthritis Rheum., 2006, 54(4), 1087-1095.
-
(2006)
Arthritis Rheum
, vol.54
, Issue.4
, pp. 1087-1095
-
-
Wessels, J.A.1
de Vries-Bouwstra, J.K.2
Heijmans, B.T.3
Slagboom, P.E.4
Goekoop-Ruiterman, Y.P.5
Allaart, C.F.6
Kerstens, P.J.7
van Zeben, D.8
Breedveld, F.C.9
Dijkmans, B.A.10
Huizinga, T.W.11
Guchelaar, H.J.12
-
51
-
-
44949192753
-
An update on methotrexate pharmacogenetics in rheumatoid arthritis
-
Ranganathan, P. An update on methotrexate pharmacogenetics in rheumatoid arthritis. Pharmacogenomics, 2008, 9(4), 439-451.
-
(2008)
Pharmacogenomics
, vol.9
, Issue.4
, pp. 439-451
-
-
Ranganathan, P.1
-
52
-
-
77954449063
-
Folate Pathway Enzyme Gene Polymorphisms and the Efficacy and Toxicity of Methotrexate in Psoriatic Arthritis
-
Chandran, V.; Siannis, F.; Rahman, P.; Pellett, F.J.; Farewell, V.T.; Gladman, D.D. Folate Pathway Enzyme Gene Polymorphisms and the Efficacy and Toxicity of Methotrexate in Psoriatic Arthritis. J. Rheumatol., 2010, 37(7), 1508-1512.
-
(2010)
J. Rheumatol
, vol.37
, Issue.7
, pp. 1508-1512
-
-
Chandran, V.1
Siannis, F.2
Rahman, P.3
Pellett, F.J.4
Farewell, V.T.5
Gladman, D.D.6
-
53
-
-
70349561519
-
Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians
-
Sharma, S.; Das, M.; Kumar, A.; Marwaha, V.; Shankar, S.; Singh, P.; Raghu, P.; Aneja, R.; Grover, R.; Arya, V.; Dhir, V.; Gupta, R.; Kumar, U.; Juyal, R.C.; K, T.B. Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians. Pharmacogenet. Genomics, 2009, 19(10), 823-828.
-
(2009)
Pharmacogenet. Genomics
, vol.19
, Issue.10
, pp. 823-828
-
-
Sharma, S.1
Das, M.2
Kumar, A.3
Marwaha, V.4
Shankar, S.5
Singh, P.6
Raghu, P.7
Aneja, R.8
Grover, R.9
Arya, V.10
Dhir, V.11
Gupta, R.12
Kumar, U.13
Juyal, R.C.14
K, T.B.15
-
54
-
-
33750298685
-
Association of methotrexate effects and singlenucleotide polymorphisms in the folate pathway in rheumatoid arthritis: Comment on the article by Wessels et al
-
author reply 3372-3373
-
Ranganathan, P. Association of methotrexate effects and singlenucleotide polymorphisms in the folate pathway in rheumatoid arthritis: comment on the article by Wessels et al. Arthritis Rheum., 2006, 54(10), 3372; author reply 3372-3373.
-
(2006)
Arthritis Rheum
, vol.54
, Issue.10
, pp. 3372
-
-
Ranganathan, P.1
-
55
-
-
78650025329
-
-
The National Center for Biotechnology Information, Available at:, Accessed July 15, 2010
-
The National Center for Biotechnology Information. SNP: single nucleotide polymorphism. Available at: http://www.ncbi.nlm.nih.gov/sites/entrez?db=snp&cmd=search&term=dbSNP (Accessed July 15, 2010).
-
SNP: Single Nucleotide Polymorphism
-
-
|