The effect of membrane receptor clustering on spatio-temporal cell signalling dynamics

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

Volumn 7223 LNCS, Issue , 2012, Pages 50-61

  Caré, Bertrand R ^a,b   Soula, Hédi A ^a,b  

^a UNIVERSITÉ DE LYON   (France)

^b EPI BEAGLE INRIA   (France)

Author keywords

autocorrelation; binding; cell signalling; clustering; computational biology; equilibrium; individual based model; kinetics; ligand; pathway; receptor

Indexed keywords

BINDING; CELL SIGNALLING; CLUSTERING; COMPUTATIONAL BIOLOGY; INDIVIDUAL-BASED MODELS; PATHWAY; RECEPTOR;

ACTIVATION ANALYSIS; AUTOCORRELATION; BIOINFORMATICS; CELL MEMBRANES; DATA PROCESSING; ECOLOGY; ENZYME KINETICS; HISTOLOGY; LIGANDS; PHASE EQUILIBRIA; TISSUE;

CYTOLOGY;

EID: 84859153484     PISSN: 03029743     EISSN: 16113349     Source Type: Book Series    
DOI: 10.1007/978-3-642-28792-3_8     Document Type: Conference Paper

References (37)

1. Heffetz, D., Zick, Y.: Receptor aggregation is necessary for activation of the soluble insulin receptor kinase. The Journal of Biological Chemistry 261(2), 889-894 (1986)
2. Flrke, R.R., Schnaith, K., Passlack, W., Wichert, M., Kuehn, L., Fabry, M., Federwisch, M., Reinauer, H.: Hormone-triggered conformational changes within the insulin-receptor ectodomain: requirement for transmembrane anchors
3. Murray, J.D.: Mathematical Biology: I. An Introduction. Springer, Heidelberg (2002)
4. Gillespie, D.T.: Stochastic simulation of chemical kinetics. Annual Review of Physical Chemistry 58(1), 35-55 (2007)
5. Berry, H.: Monte carlo simulations of enzyme reactions in two dimensions: fractal kinetics and spatial segregation. Biophysical Journal 83(4), 1891-1901 (2002)
6. Kholodenko, B.N., Hoek, J.B., Westerhoff, H.V.: Why cytoplasmic signalling proteins should be recruited to cell membranes. Trends in Cell Biology 10(5), 173-178 (2000)
7. Berg, H.C., Purcell, E.M.: Physics of chemoreception. Biophysical Journal 20(2), 193-219 (1977)
8. Goldstein, B., Dembo, M.: Approximating the effects of diffusion on reversible reactions at the cell surface: ligand-receptor kinetics. Biophysical Journal 68(4), 1222-1230 (1995)
9. Erickson, J., Goldstein, B., Holowka, D., Baird, B.: The effect of receptor density on the forward rate constant for binding of ligands to cell surface receptors. Biophysical Journal 52(4), 657-662 (1987)
10. Zwanzig, R., Szabo, A.: Time dependent rate of diffusion-influenced ligand binding to receptors on cell surfaces. Biophysical Journal 60(3), 671-678 (1991)
11. Endres, R.G., Wingreen, N.S.: Accuracy of direct gradient sensing by single cells. Proceedings of the National Academy of Sciences 105(41), 15749-15754 (2008)
12. Endres, R.G., Wingreen, N.S.: Maximum likelihood and the single receptor. Physical Review Letters 103(15), 158101 (2009); PMID: 19905667
13. Singer, S.J., Nicolson, G.L.: The fluid mosaic model of the structure of cell membranes. Science 175(23), 720-731 (1972)
14. Koppel, D.E., Sheetz, M.P., Schindler, M.: Matrix control of protein diffusion in biological membranes. Proceedings of the National Academy of Sciences of the United States of America 78(6), 3576-3580 (1981)
15. Chung, I., Akita, R., Vandlen, R., Toomre, D., Schlessinger, J., Mellman, I.: Spatial control of EGF receptor activation by reversible dimerization on living cells. Nature 464(7289), 783-787 (2010)
16. Simons, K., Ikonen, E.: Functional rafts in cell membranes. Nature 387(6633), 569-572 (1997)
17. Simons, K., Toomre, D.: Lipid rafts and signal transduction. Nature Reviews. Molecular Cell Biology 1(1), 31-39 (2000)
18. Schuck, S., Simons, K.: Polarized sorting in epithelial cells: raft clustering and the biogenesis of the apical membrane. Journal of Cell Science 117(25), 5955-5964 (2004)
19. Brown, D.A., London, E.: Functions of lipid rafts in biological membranes. Annual Review of Cell and Developmental Biology 14(1), 111-136 (1998)
20. Zhang, J., Leiderman, K., Pfeiffer, J.R.,Wilson, B.S., Oliver, J.M., Steinberg, S.L.: Characterizing the topography of membrane receptors and signaling molecules from spatial patterns obtained using nanometer-scale electron-dense probes and electron microscopy. Micron. 37(1), 14-34 (2006) (Oxford, England: 1993)
21. Gustavsson, J., Parpal, S., Karlsson, M., Ramsing, C., Thorn, H., Borg, M., Lindroth, M., Peterson, K.H., Magnusson, K.-E., Strälfors, P.: Localization of the insulin receptor in caveolae of adipocyte plasma membrane. The FASEB Journal 13(14), 1961-1971 (1999)
22. Parpal, S.: Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control. Journal of Biological Chemistry 276(13), 9670-9678 (2000)
23. Lee, S., Mandic, J., Van Vliet, K.J.: Chemomechanical mapping of ligand-receptor binding kinetics on cells. Proceedings of the National Academy of Sciences of the United States of America 104(23), 9609-9614 (2007)
24. Lim, K., Yin, J.: Localization of receptors in lipid rafts can inhibit signal transduction. Biotechnology and Bioengineering 90(6), 694-702 (2005)
25. Vitte, J., Benoliel, A.-M., Eymeric, P., Bongrand, P., Pierres, A.: Beta-1 integrin-mediated adhesion be initiated by multiple incomplete bonds, thus accounting for the functional importance of receptor clustering. Biophysical Journal 86(6), 4059-4074 (2004)
26. Bray, D., Levin, M.D., Morton-Firth, C.J.: Receptor clustering as a cellular mechanism to control sensitivity. Nature 393, 85-88 (1998)
27. Mello, B.A., Shaw, L., Tu, Y.: Effects of receptor interaction in bacterial chemotaxis. Biophysical Journal 87(3), 1578-1595 (2004)
28. Mahama, P.A., Linderman, J.J.: A monte carlo study of the dynamics of g-protein activation. Biophysical Journal 67(3), 1345-1357 (1994)
29. Wanant, S., Quon, M.J.: Insulin receptor binding kinetics: modeling and simulation studies. Journal of Theoretical Biology 205(3), 355-364 (2000)
30. Shea, L.D., Omann, G.M., Linderman, J.J.: Calculation of diffusion-limited kinetics for the reactions in collision coupling and receptor cross-linking. Biophysical Journal 73(6), 2949-2959 (1997)
31. Shea, L.D., Linderman, J.J.: Compartmentalization of receptors and enzymes affects activation for a collision coupling mechanism. Journal of Theoretical Biology 191(3), 249-258 (1998)
32. Gopalakrishnan, M.: Effects of receptor clustering on ligand dissociation kinetics: Theory and simulations. Biophysical Journal 89(6), 3686-3700 (2005)
33. Ghosh, S., Gopalakrishnan, M., Forsten-Williams, K.: Self-consistent theory of reversible ligand binding to a spherical cell. Physical Biology 4(4), 344-354 (2008)
34. Fallahi-Sichani, M., Linderman, J.J.: Lipid Raft-Mediated regulation of G-Protein coupled receptor signaling by ligands which influence receptor dimerization: A computational study. PLoS ONE 4(8), e6604 (2009)
35. Caré, B.R., Soula, H.A.: Impact of receptor clustering on ligand binding. BMC Systems Biology 5(1), 48 (2011)
36. Carpentier, J.L., Paccaud, J.P., Gorden, P., Rutter, W.J., Orci, L.: Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation. Proceedings of the National Academy of Sciences of the United States of America 89(1), 162-166 (1992)
37. Giudice, J., Leskow, F.C., Arndt-Jovin, D.J., Jovin, T.M., Jares-Erijman, E.A.: Differential endocytosis and signaling dynamics of insulin receptor variants IR-A and IR-B. Journal of Cell Science 124(Pt 5), 801-811 (2011)