Impact of receptor clustering on ligand binding

BMC Systems Biology

Volumn 5, Issue , 2011, Pages

  Caré, Bertrand R ^a,b   Soula, Hédi A ^a,b  

^a UNIVERSITÉ DE LYON   (France)

^b INRIA RHÔNE ALPES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; LIGAND;

ALGORITHM; ARTICLE; BIOLOGICAL MODEL; DIFFUSION; METABOLISM; MONTE CARLO METHOD;

ALGORITHMS; DIFFUSION; LIGANDS; MODELS, BIOLOGICAL; MONTE CARLO METHOD; RECEPTORS, CELL SURFACE;

EID: 79953189445     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-5-48     Document Type: Article

References (40)

1. Heffetz D, Yehiel Z. Receptor Aggregation Is Necessary for Activation of the Soluble Insulin Receptor Kinase. J Biol Chem 1986, 261:889-894.
2. Flörke RR, Schnaith K, Passlack W, Wichert M, Kuehn L, Fabry M, Federwisch M, Reinauer H. Hormone-triggered conformation changes within the insulin-receptor ectodomain: requirement for transmembrane anchors. Biochem J 2001, 360:189-198. 1222217, 11696007.
3. Changeux JP, Edelstein SJ. Allosteric Receptors after 30 Years. Neuron 1998, 21:959-980. 10.1016/S0896-6273(00)80616-9, 9856454.
4. Greenfield D, McEvoy AL, Shroff H, Crooks GE, Wingreen NS, Betzig E, Liphardt J. Self-Organization of the Escherichia coli Chemotaxis Network Imaged with Super-Resolution Light Microscopy. PLoS Biology 2009, 7:6.
5. Murray JD. Mathematical Biology: I. An Introduction 2002, Springer.
6. Gillespie DT. Stochastic simulation of chemical kinetics. Annual review of physical chemistry 2007, 58:35-55. 10.1146/annurev.physchem.58.032806.104637, 17037977.
7. Berry H. Monte Carlo Simulations of Enzyme Reactions in Two Dimensions: Fractal Kinetics and Spatial. Biophys J 2002, 83:1891-1901. 10.1016/S0006-3495(02)73953-2, 1302281, 12324410.
8. Kholodenko BN, Hoek JB, Westerhoff HV. Why cytoplasmic signalling proteins should be recruited to cell membranes. trends in Cell Biology 2000, 10:173-178. 10.1016/S0962-8924(00)01741-4, 10754559.
9. Berg HC, Purcell EM. Physics of Chemoreception. Biophys J 1977, 20:193-219. 10.1016/S0006-3495(77)85544-6, 1473391, 911982.
10. Goldstein B, Dembo M. Approximating the Effects of Diffusion on Reversible Reactions at the Cell Surface: Ligand-Receptor Kinetics. Biophys J 1995, 68:1222-1230. 10.1016/S0006-3495(95)80298-5, 1282020, 7787014.
11. Erickson J, Goldstein B, Holowka D, Baird B. The effect of receptor density on the forward rate constant for binding of ligands to cell surface receptors. Biophysical Journal 1987, 52. 10.1016/S0006-3495(87)83258-7, 1330059, 2960385.
12. Zwanzig R, Szabo A. Time dependent rate of diffusion-influenced ligand binding to receptors on cell surfaces. Biophys J 1991, 60:671-678. 10.1016/S0006-3495(91)82096-3, 1260110, 1657231.
13. Endres RG, Wingreen NS. Accuracy of direct gradient sensing by single cells. Proc Natl Acad Sci USA 2008, 105(41):15749-15754. 10.1073/pnas.0804688105, 2572938, 18843108.
14. Endres R, Wingreen N. Accuracy of direct gradient sensing by cell-surface receptors. Prog Biophys Mol Biol 2009,
15. Singer SJ, Nicolson GL. The Fluid Mosaic Model of the Structure of Cell Membranes. Science 1972, 175:720-731. 10.1126/science.175.4023.720, 4333397.
16. Saffman PG, Delbrück M. Brownian motion in biological membranes. Proc Natl Acad Sci USA 1975, 72(8):3111-3. 10.1073/pnas.72.8.3111, 432930, 1059096.
17. Chung I, Akita R, Vandlen R, Toomre D, Schlessinger J, Mellman I. Spatial control of EGF receptor activation by reversible dimerization on living cells. Nature 2010, 464:783-787. 10.1038/nature08827, 20208517.
18. Simons K, Ikonen E. Functional rafts in cell membranes. Nature 1997, 387:569-572. 10.1038/42408, 9177342.
19. Simons K, Toomre D. Lipid Rafts and Signal Transduction. Nature Reviews 2000, 1:31-41.
20. Simons K, Vaz WLC. Model systems, lipid rafts, and cell membranes. Annu Rev Biophys Biomol Struct 2004, 33:269-95. 10.1146/annurev.biophys.32.110601.141803, 15139814.
21. Brown DA, London E. Functions of Lipid Rafts in Biological Membranes. Annual Reviews of Cell and Developmental Biology 1998, 14:111-36.
22. Gustavsson J, Santiago P, Karlsson M, Ramsing C, Thorn H, Borg M, Lindroth M, Peterson KH, Magnusson KE, Stralfors P. Localization of the insulin receptor in caveolae of adipocyte plasma membrane. FASEB Journal 1999, 13:1961-1971.
23. Parpal S, Karlsson M, Thorn H, Strålfors P. Cholesterol Depletion Disrupts Caveolae and Insulin Receptor Signaling for Metabolic Control via Insulin Receptor Substrate-1, but Not for Mitogen-activated Protein Kinase Control. J Biol Chem 2001, 276. 10.1074/jbc.M007454200, 11121405.
24. Lee S, Mandic J, Vliet KJV. Chemomechanical mapping of ligand-receptor binding kinetics on cells. Proc Natl Acad Sci USA 2007, 104(23):9609-14. 10.1073/pnas.0702668104, 1887608, 17535923.
25. Vitte J, Benoliel AM, Eymeric P, Bongrand P, Pierres A. Beta-1 integrin-mediated adhesion may be initiated by multiple incomplete bonds, thus accounting for the functional importance of receptor clustering. Biophys J 2004, 86(6):4059-74. 10.1529/biophysj.103.038778, 1304306, 15189901.
26. Bray D, Levin MD, Morton-Firth CJ. Receptor clustering as a cellular mechanism to control sensitivity. Nature 1998, 393:85-88. 10.1038/30018, 9590695.
27. Mello BA, Shaw L, Tu Y. Effects of Receptor Interaction in Bacterial Chemotaxis. Biophys J 2004, 87:1578-1595. 10.1529/biophysj.104.042739, 1304564, 15345538.
28. Mahama PA, Linderman JJ. A Monte Carlo Study of the Dynamics of G-Protein Activation. Biophys J 1994, 67:1345-1357. 10.1016/S0006-3495(94)80606-X, 1225491, 7811949.
29. Wanant S, Quon MJ. Insulin Receptor Binding Kinetics: Modeling and Simulation Studies. Journal of theoretical Biology 2000, 205:355-364. 10.1006/jtbi.2000.2069, 10882558.
30. Shea LD, Linderman JJ. Calculation of Diffusion-Limited Kinetics for the Reactions in Collision Coupling and Receptor Cross-Linking. Biophys J 1997, 73:2949-2959. 10.1016/S0006-3495(97)78323-1, 1181200, 9414209.
31. Shea LD, Linderman JJ. Compartmentalization of Receptors and Enzymes Affects Activation for a Collision Coupling Mechanism. Journal of theoretical Biology 1998, 191:249-258.
32. Gopalakrishnan M, Forsten-Williams K, Nugent MA, Täuber UC. Effects of receptor clustering on ligand dissociation kinetics: theory and simulations. Biophys J 2005, 89(6):3686-700. 10.1529/biophysj.105.065300, 1366939, 16150967.
33. Ghosh S, Gopalakrishnan M, Forsten-Williams K. Self-consistent theory of reversible ligand binding to a spherical cell. Phys Biol 2007, 4:344-354.
34. Fallahi-Sichani M, Linderman JJ. Lipid Raft-mediated Regulation of G-Protein Coupled Receptor Signaling by Ligands which Influence Receptor Dimerization: A Computational Study. PLoS ONE 2009, 4:8.
35. Goldstein B, Wiegel FW. The effect of receptor clustering on diffusion-limited forward rate constants. Biophys J 1983, 43:121-5. 10.1016/S0006-3495(83)84330-6, 1329275, 6309261.
36. Juska A. Minimal models of multi-site ligand-binding kinetics. J Theor Biol 2008, 255(4):396-403. 10.1016/j.jtbi.2008.08.030, 18851980.
37. Weiss JN. The Hill equation revisited: uses and misuses. FASEB 1997, 11:835-841.
38. Tanford C, Reynolds JA, Johnson EA. Thermodynamic and kinetic cooperativity in ligand binding to multiple sites on a protein: Ca2+ activation of an ATP-driven Ca pump. Proc Natl Acad Sci USA 1985, 82:4688-4692. 10.1073/pnas.82.14.4688, 390451, 3161074.
39. Linderman JJ, Lauffenburger DA. Receptors: models for binding, trafficking, and signaling 1993, Oxford University Press.
40. Coombs D, Straube R, Ward MJ. Diffusion on a Sphere with Localized Traps: Mean First Passage Time, Eigenvalue Asymptotics, and Fekete Points. SIAM Journal on Applied Mathematics 2009, 70:302-332.