Accuracy of direct gradient sensing by single cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 41, 2008, Pages 15749-15754

  Endres, Robert G ^a,b   Wingreen, Ned S ^a  

^a PRINCETON UNIVERSITY   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Chemotaxis; Noise; Receptors

Indexed keywords

CELL SURFACE RECEPTOR; CYCLIC AMP;

ARTICLE; CELL; CELL MOTION; CELL SURFACE; CELL TYPE; DICTYOSTELIUM DISCOIDEUM; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

BIOLOGICAL TRANSPORT; CELLS; CYCLIC AMP; DIFFUSION; MODELS, BIOLOGICAL; RECEPTORS, CYCLIC AMP;

DICTYOSTELIUM DISCOIDEUM; SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 57349128869     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0804688105     Document Type: Article

References (45)

1. Berg HC (1999) Motile behavior of bacteria. Phys Today 53:24-29.
2. Mao H, Cremer PS, Manson MD (2003) A sensitive versatile microfluidic assay for bacterial chemotaxis. Proc Natl Acad Sci USA 100:5449-5454.
3. Arkowitz RA (1999) Responding to attraction: Chemotaxis and chemotropism in Dictyostelium and yeast. Trends Cell Biol 9:20-37.
4. Manahan CL, Iglesias PA, Long Y, Devreotes PN (2004) Chemoattractant signaling in dictyostelium discoideum. Annu Rev Cell Dev Biol 20:223-253.
5. Mato JM, Losada A, Nanjundiah V, Konijn TM (1975) Signal input for a chemotactic response in the cellular slime mold Dictyostelium discoideum. Proc Natl Acad Sci USA 72:4991-4993.
6. van Haastert PJM, Postma M (2007) Biased random walk by stochastic fluctuations of chemoattractant-receptor interactions at the lower limit of detection. Biophys J 93:1787-1796.
7. Zigmond SH (1977) Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors. J Cell Biol 75:606-616.
8. Berg HC, Purcell EM (1977) Physics of chemoreception. Biophys J 20:193-219.
9. Bray D, Levin MD, Morton-Firth CJ (1998) Receptor clustering as a cellular mechanism to control sensitivity. Nature 393:85-88.
10. Bialek W, Setayeshgar S (2005) Physical limits to biochemical signaling. Proc Natl Acad Sci USA 102:10040-10045.
11. Mello BA, Tu Y (2005) An allosteric model for heterogeneous receptor complexes: Understanding bacterial chemotaxis responses to multiple stimuli. Proc Natl Acad Sci USA 102:17354-17359.
12. Keymer JE, Endres RG, Skoge M, Meir Y, Wingreen NS (2006) Chemosensing in Escherichia coli: Two regimes of two-state receptors. Proc Natl Acad Sci USA 103:1786-1791.
13. Endres RG, Wingreen NS (2006) Precise adaptation in bacterial chemotaxis through "assistance neighborhoods." Proc Natl Acad Sci USA 103:13040-13044.
14. Jackson JD (1975) in Classical Electrodynamics (Wiley, New York), 2nd Ed, Chap 4.4.
15. Segall JE (1993) Polarization of yeast cells in spatial gradients of α mating factor. Proc Natl Acad Sci USA 90:8332-8336.
16. Mukherjee S, Ghosh RN, Maxfield FR (1997) Endocytosis. Physiol Rev 77:759-803.
17. Ferguson SS (2001) Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling. Pharmacol Rev 53:1-24.
18. Caterina MJ, Hereld D, Devreotes PN (1995) Occupancy of the Dictyostelium cAMP receptor, cAR1, induces a reduction in affinity which depends upon COOH-terminal serine residues. J Biol Chem 270:4418-4423.
19. Malchow D, Nägele B, Schwarz H, Gerisch G (1972) Membrane-bound cyclic AMP phosphodiesterase in chemotactically responding cells of Dictyostelium discoideum. Eur J Biochem 28:136-142.
20. Shapiro RI, Franke J, Luna EJ, Kessin RH (1983) A comparison of the membrane-bound and extracellular cyclic AMP phosphodiesterases of Dictyostelium discoideum. Biochim Biophys Acta 785:49-57.
21. Sucgang R, Weijer CJ, Siegert F, Franke J, Kessin RH (1997) Null mutations of the Dictyostelium cyclic nucleotide phosphodiesterase gene block chemotactic cell movement in developing aggregates. Dev Biol 192:181-192.
22. Rifkin JL (2001) Folate reception by vegetative Dictyostelium discoideum amoebae: distribution of receptors and trafficking of ligand. Cell Motil Cytoskeleton 48:121-129.
23. Schandel KA, Jenness DD (1994) Direct evidence for ligand-induced internalization of the yeast α-factor pheromone receptor. Mol Cell Biol 14:7245-7255.
24. Hicks JB, Herskowitz I (1976) Evidence for a new diffusible element of mating pheromones in yeast. Nature 260:246-248.
25. Barkai N, Rose MD, Wingreen NS (1998) Protease helps yeast find mating partners. Nature 396:422-423.
26. Ciejek E, Thorner J (1979) Recovery of S. cerevisiae a cells from G1 arrest by α factor pheromone requires endopeptidase action. Cell 18:623-635.
27. Minina S, Reichman-Fried M, Raz E (2007) Control of receptor internalization, signaling level, and precise arrival at the target in guided cell migration. Curr Biol 17:1164-1172.
28. Li L, Nørrelykke SF, Cox EC (2008) Persistent cell motion in the absence of external signals: A search strategy for eukaryotic cells PLoS One 3:e2093.
29. Thar R, Kühl M (2003) Bacteria are not too small for spatial sensing of chemical gradients: An experimental evidence. Proc Natl Acad Sci USA 100: 5748-5753.
30. Meinhardt H (1999) Orientation of chemotactic cells and growth cones: Models and mechanisms. J Cell Sci 112:2867-2874.
31. Skupsky R, Losert W, Nossal RJ (2005) Distinguishing modes of eukaryotic gradient sensing. Biophys J 89:2806-2823.
32. Narang A (2006) Spontaneous polarization in eukaryotic gradient sensing: A mathematical model based on mutual inhibition of frontness and backness pathways. J Theor Biol 240:538-553.
33. Levine H, Kessler DA, Rappel WJ (2006) Directional sensing in eukaryotic chemotaxis: A balanced inactivation model. Proc Natl Acad Sci USA 103:9761-9766.
34. Krishnan J, Iglesias PA (2007) Receptor-mediated and intrinsic polarization and their interaction in chemotaxing cells. Biophys J 92:816-830.
35. Onsum M, Rao CV (2007) A mathematical model for neutrophil gradient sensing and polarization. PLoS Comput Biol 3:e36.
36. Otsuji M et al. (2007) A mass conserved reaction-diffusion system captures properties of cell polarity. PLoS Comput Biol 3:e108.
37. Dawes AT, Bard Ermentrout G, Cytrynbaum EN, Edelstein-Keshet L (2006) Actin filament branching and protrusion velocity in a simple 1D model of a motile cell. J Theor Biol 242:265-279.
38. Dawes AT, Edelstein-Keshet L (2007) Phosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cell. Biophys J 92:744-768.
39. Pálsson E et al. (1997) Selection for spiral waves in the social amoebae Dictyostelium. Proc Natl Acad Sci USA 94:13719-13723.
40. Goodhill GJ, Urbach JS (1999) Theoretical analysis of gradient detection by growth cones. J Neurobiol 41:230-241.
41. Wylie CS, Levine H, Kessler DA (2006) Fluctuation-induced instabilities in front propagation up a comoving reaction gradient in two dimensions. Phys Rev E Stat Nonlin Soft Matter Phys 74:016119.
42. Iglesias PA, Devreotes PN (2008) Navigating through models of chemotaxis. Curr Opin Cell Biol 20:35-40.
43. Andrews BW, Iglesias PA (2007) An information-theoretic characterization of the optimal gradient sensing response of cells. PLoS Comput Biol 3:e153.
44. Samadani A, Mettetal J, van Oudenaarden A (2006) Cellular asymmetry and individuality in directional sensing. Proc Natl Acad Sci USA 103:11549-11554.
45. Skupsky R, McCann C, Nossal R, Losert W (2007) Bias in the gradient-sensing response of chemotactic cells. J Theor Biol 247:242-258.