A high-throughput screening method for small-molecule inhibitors of the aberrant mutant SOD1 and dynein complex interaction

Journal of Biomolecular Screening

Volumn 17, Issue 3, 2012, Pages 314-326

  Tang, Xiaohu ^a   Seyb, Kathleen I ^b   Huang, Mickey ^b   Schuman, Eli R ^b   Shi, Ping ^a   Zhu, Haining ^a   Glicksman, Marcie A ^b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

cell based assays; CNS and PNS diseases; fluorescence methods; protein protein interactions

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; DYNEIN ADENOSINE TRIPHOSPHATASE; PROTEIN INHIBITOR; SMALL MOLECULE INHIBITOR; UNCLASSIFIED DRUG;

ALPHALISA; ANALYTIC METHOD; ARTICLE; CELL LYSATE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH THROUGHPUT SCREENING; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

AMYOTROPHIC LATERAL SCLEROSIS; CELL LINE; DYNEINS; ENZYME INHIBITORS; GLUTATHIONE TRANSFERASE; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; PROTEIN STRUCTURE, QUATERNARY; SUPEROXIDE DISMUTASE;

EID: 84859091355     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111429595     Document Type: Article

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