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Volumn 126, Issue 2, 2012, Pages 291-297

Identification and characterization of adverse effects in 21st Century toxicology

Author keywords

Adaptive; Adverse; High data content assays; RPTC; RRR

Indexed keywords

ADAPTATION; ADVERSE DRUG REACTION; ARTICLE; BIOCHEMISTRY; COMPUTER MODEL; CYTOTOXICITY; DECISION MAKING; DOSIMETRY; EXPOSURE; GENOTOXICITY; IN VITRO STUDY; RELEVANT PATHWAY OF TOXICOLOGICAL CONCERN; RELEVANT RESPONSE FOR REGULATION; RISK ASSESSMENT; TOXICITY TESTING; TOXICOLOGY;

EID: 84859082867     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr350     Document Type: Article
Times cited : (80)

References (33)
  • 1
    • 59149106151 scopus 로고    scopus 로고
    • st century: Bringing the vision to life
    • st century: Bringing the vision to life. Toxicol. Sci. 107, 324-330.
    • (2009) Toxicol. Sci. , vol.107 , pp. 324-330
    • Andersen, M.1    Krewski, D.2
  • 2
    • 77955906570 scopus 로고    scopus 로고
    • st century: Moving from discussion to action
    • st century: Moving from discussion to action. Toxicol. Sci. 117, 17-24.
    • (2010) Toxicol. Sci. , vol.117 , pp. 17-24
    • Andersen, M.E.1    Krewski, D.2
  • 4
    • 79955724702 scopus 로고    scopus 로고
    • A mechanistic redefinition of adverse effects-A key step in the toxicity testing paradigm shift
    • Boekelheide, K., and Andersen, M. E. (2010). A mechanistic redefinition of adverse effects-A key step in the toxicity testing paradigm shift. ALTEX 27, 243-252.
    • (2010) ALTEX , vol.27 , pp. 243-252
    • Boekelheide, K.1    Andersen, M.E.2
  • 5
    • 77951605817 scopus 로고    scopus 로고
    • st century: Using the new toxicity testing paradigm to create a taxonomy of adverse effects
    • st century: Using the new toxicity testing paradigm to create a taxonomy of adverse effects. Toxicol. Sci. 114, 20-24.
    • (2010) Toxicol. Sci. , vol.114 , pp. 20-24
    • Boekelheide, K.1    Campion, S.N.2
  • 7
    • 74949127956 scopus 로고    scopus 로고
    • st century: A view from the chemical industry
    • st century: A view from the chemical industry. Toxicol. Sci. 112, 297-302.
    • (2009) Toxicol. Sci. , vol.112 , pp. 297-302
    • Bus, J.S.1    Becker, R.A.2
  • 10
    • 70349278813 scopus 로고    scopus 로고
    • st century toxicity testing
    • st century toxicity testing. Toxicol. Sci. 111, 226-232.
    • (2009) Toxicol. Sci. , vol.111 , pp. 226-232
    • Cohen Hubal, E.A.1
  • 12
  • 13
    • 22544453881 scopus 로고    scopus 로고
    • The no-observed-adverse-effectlevel in drug safety evaluations: Use, issues and definition(s)
    • Dorato, M. A., and Engelhardt, J. A. (2005). The no-observed-adverse-effectlevel in drug safety evaluations: Use, issues and definition(s). Regul. Toxicol. Pharmacol. 42, 265-264.
    • (2005) Regul. Toxicol. Pharmacol. , vol.42 , pp. 264-265
    • Dorato, M.A.1    Engelhardt, J.A.2
  • 14
    • 73449144437 scopus 로고    scopus 로고
    • Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation
    • Fannin, R. D., Russo, M., O'Connell, T. M., Gerrish, K., Winnike, J. H., Macdonald, J., Newton, J., Malik, S., Sieber, S. O., Parker, J., et al. (2010). Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation. Hepatology 51, 227-236.
    • (2010) Hepatology , vol.51 , pp. 227-236
    • Fannin, R.D.1    Russo, M.2    O'Connell, T.M.3    Gerrish, K.4    Winnike, J.H.5    Macdonald, J.6    Newton, J.7    Malik, S.8    Sieber, S.O.9    Parker, J.10
  • 16
    • 77957345655 scopus 로고    scopus 로고
    • A framework for assessing causality and adverse effects in humans with a case study of sulfur dioxide
    • Goodman, J. E., Dodge, D. G., and Bailey, L. A. (2010). A framework for assessing causality and adverse effects in humans with a case study of sulfur dioxide. Regul. Toxicol. Pharmacol. 58, 308-322.
    • (2010) Regul. Toxicol. Pharmacol. , vol.58 , pp. 308-322
    • Goodman, J.E.1    Dodge, D.G.2    Bailey, L.A.3
  • 17
    • 65549145511 scopus 로고    scopus 로고
    • st century-Mapping the road ahead
    • st century-Mapping the road ahead. Toxicol. Sci. 109, 18-23.
    • (2009) Toxicol. Sci. , vol.109 , pp. 18-23
    • Hartung, T.1
  • 21
  • 22
    • 61349141927 scopus 로고    scopus 로고
    • st Century in a regulatory context: Another Ames test?... or a new edition of "the Red Book"?
    • st Century in a regulatory context: Another Ames test?... or a new edition of "the Red Book"? Toxicol. Sci. 108, 19-21.
    • (2009) Toxicol. Sci. , vol.108 , pp. 19-21
    • Meek, M.E.1    Doull, J.2
  • 25
    • 69249126232 scopus 로고    scopus 로고
    • TOX21: New dimensions of toxicity testing
    • Schmidt, C. W. (2009). TOX21: New dimensions of toxicity testing. Environ. Health Perspect. 117, A349-A353.
    • (2009) Environ. Health Perspect , vol.117
    • Schmidt, C.W.1
  • 26
    • 26844515332 scopus 로고    scopus 로고
    • Gene expression profiling of responses to dimethylarsinic acid in female F344 rat urothelium
    • Sen, B., Wang, A., Hester, S. D., Robertson, J. L., and Wolf, D. C. (2005). Gene expression profiling of responses to dimethylarsinic acid in female F344 rat urothelium. Toxicology 215, 214-226.
    • (2005) Toxicology , vol.215 , pp. 214-226
    • Sen, B.1    Wang, A.2    Hester, S.D.3    Robertson, J.L.4    Wolf, D.C.5
  • 27
    • 36148999849 scopus 로고    scopus 로고
    • Identification of interspecies concordance of mechanisms of arsenicinduced bladder cancer
    • Sen, B., Wolf, D. C., Turpaz, Y., Bugrim, A., Retief, J., and Hester, S. D. (2007). Identification of interspecies concordance of mechanisms of arsenicinduced bladder cancer. Toxicol. In Vitro 21, 1513-1529.
    • (2007) Toxicol. In Vitro , vol.21 , pp. 1513-1529
    • Sen, B.1    Wolf, D.C.2    Turpaz, Y.3    Bugrim, A.4    Retief, J.5    Hester, S.D.6
  • 28
    • 70349288028 scopus 로고    scopus 로고
    • Cellular stress response pathway system as a sentinel ensemble in toxicological screening
    • Simmons, S. O., Fan, C.-Y., and Ramabhadran, R. (2009). Cellular stress response pathway system as a sentinel ensemble in toxicological screening. Toxicol. Sci. 111, 202-225.
    • (2009) Toxicol. Sci. , vol.111 , pp. 202-225
    • Simmons, S.O.1    Fan, C.-Y.2    Ramabhadran, R.3
  • 32
    • 0004104069 scopus 로고    scopus 로고
    • U.S. Environmental Protection Agency (USEPA). Accessed February 6, 2012
    • U.S. Environmental Protection Agency (USEPA). (2009). Integrated Risk Information System (IRIS) Glossary. Available at: http://www.epa.gov/ncea/iris/help_gloss.htm. Accessed February 6, 2012.
    • (2009) Integrated Risk Information System (IRIS) Glossary
  • 33
    • 67650718169 scopus 로고    scopus 로고
    • st century paradigm for evaluating the health hazards of nanoscale materials
    • st century paradigm for evaluating the health hazards of nanoscale materials. Toxicol. Sci. 110, 251-254.
    • (2009) Toxicol. Sci. , vol.110 , pp. 251-254
    • Walker, N.J.1    Bucher, J.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.