Identification and characterization of reactive metabolites in natural products-driven drug discovery

Journal of Natural Products

Volumn 75, Issue 3, 2012, Pages 507-513

  Njuguna, Nicholas M ^a   Masimirembwa, Collen ^b   Chibale, Kelly ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b African Institute of Biomedical Science and Technology   (Zimbabwe)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLENE DERIVATIVE; ALKENE DERIVATIVE; AMODIAQUINE; ANILIDE; ANILINE DERIVATIVE; ARISTOLOCHIC ACID; BERGAMOTTIN; CARBAMAZEPINE; DICLOFENAC; DRUG METABOLITE; FURAN DERIVATIVE; GLABRIDIN; HYDRAZINE DERIVATIVE; KETOCONAZOLE; METHYSTICIN; NATURAL PRODUCT; PARACETAMOL; PULEGONE; SAFROLE; THIOPHENE DERIVATIVE; VALPROIC ACID; XANTHOHUMOL;

ACCURACY; BIOTRANSFORMATION; CHEMICAL MODIFICATION; COVALENT BOND; CYTOTOXICITY; DRUG SAFETY; DRUG SCREENING; HUMAN; NONHUMAN; RELIABILITY; REVIEW; UNSPECIFIED SIDE EFFECT; XENOBIOTIC METABOLISM;

BIOLOGICAL AGENTS; BIOTRANSFORMATION; DRUG DISCOVERY; HUMANS; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS;

EID: 84859079394     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np200786j     Document Type: Review

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