BFGF-containing electrospun gelatin scaffolds with controlled nano-architectural features for directed angiogenesis

Acta Biomaterialia

Volumn 8, Issue 5, 2012, Pages 1778-1791

  Montero, Ramon B ^a   Vial, Ximena ^a   Nguyen, Dat Tat ^a   Farhand, Sepehr ^c   Reardon, Mark ^d   Pham, Si M ^a,b   Tsechpenakis, Gavriil ^c   Andreopoulos, Fotios M ^a,b  

^a University of Miami College of Engineering   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c IN 46202 USA   (United States)

^d Department of Biology   (United States)

Author keywords

Angiogenesis; BFGF; Cell orientation; Electrospinning; Scaffolds

Indexed keywords

ARCHITECTURE; CELL CULTURE; CELL PROLIFERATION; ELECTRIC FIELDS; ENDOTHELIAL CELLS; FABRICATION; FIBERS; LOADING; NEEDLES; SCAFFOLDS; SCAFFOLDS (BIOLOGY);

ANGIOGENESIS; BASIC FIBROBLAST GROWTH FACTOR; BFGF; CELL ORIENTATION; CELL-BE; CELL/B.E; CELL/BE; COLLECTOR PLATES; CYTOKINES; GROWTH FACTOR;

ELECTROSPINNING;

FIBROBLAST GROWTH FACTOR 2; GELATIN; GELATIN B; GROWTH FACTOR; MOLECULAR SCAFFOLD; POLYMER; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOSKELETON; ELECTRIC FIELD; ELECTRODE; HUMAN; HUMAN CELL; NEEDLE; PARTICLE SIZE; PRIORITY JOURNAL;

EID: 84859060082     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.12.008     Document Type: Article

References (54)

1. A.H. Zisch, M.P. Lutolf, and J.A. Hubbell Biopolymeric delivery matrices for angiogenic growth factors Cardiovasc Pathol 12 2003 295 310
2. M. Biondi, F. Ungaro, F. Quaglia, and P.A. Netti Controlled drug delivery in tissue engineering Adv Drug Delivery Rev 60 2008 229 242
3. S.B. Freedman, and J.M. Isner Therapeutic angiogenesis for ischemic cardiovascular disease J Mol Cell Cardiol 33 2001 379 393
4. M. Hockel, K. Schlenger, S. Doctrow, T. Kissel, and P. Vaupel P Therapeutic angiogenesis Arch Surg 128 1993 423 429
5. E.A. Phelps, and A.J. Garcia Update on therapeutic vascularization strategies Regen Med 4 2009 65 80
6. C. Spadaccio, M. Chello, M. Trombetta, A. Rainer, Y. Toyoda, and J.A. Genovese Drug releasing systems in cardiovascular tissue engineering J Cell Mol Med 13 2009 422 439
7. J.A. Eble, and S. Niland The extracellular matrix of blood vessels Curr Pharm Des 15 2009 1385 1400
8. K.R. Chien, I.J. Domian, and K.K. Parker Cardiogenesis and the complex biology of regenerative cardiovascular medicine Science 322 2008 1494 1497
9. G. Krenning, J.R. Moonen, M.J. van Luyn, and M.C. Harmsen Generating new blood flow: integrating developmental biology and tissue engineering Trends Cardiovasc Med 18 2008 312 323
10. V.S. LeBleu, B. Macdonald, and R. Kalluri Structure and function of basement membranes Exp Biol Med (Maywood) 232 2007 1121 1129
11. A. de Mel, G. Jell, M.M. Stevens, and A.M. Seifalian Biofunctionalization of biomaterials for accelerated in situ endothelialization: a review Biomacromolecules 9 2008 2969 2979
12. F.G. Spinale Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function Physiol Rev 87 2007 1285 1342
13. V. Vogel, and M.P. Sheetz Cell fate regulation by coupling mechanical cycles to biochemical signaling pathways Curr Opin Cell Biol 21 2009 38 46
14. J.C. Friedland, M.H. Lee, and D. Boettiger Mechanically activated integrin switch controls alpha5 beta1 function Science 323 2009 642 644
15. H. Layman, M. Sacasa, A.E. Murphy, A.M. Murphy, S.M. Pham, and F.M. Andreopoulos Co-delivery of FGF-2 and G-CSF from gelatin-based hydrogels as angiogenic therapy in a murine critical limb ischemic model Acta Biomater 5 2009 230 239
16. H. Layman, A.A. Rahnemai-Azar, S.M. Pham, G. Tsechpenakis, and F.M. Andreopoulos Synergistic angiogenic effect of codelivering fibroblast growth factor 2 and granulocyte-colony stimulating factor from fibrin scaffolds and bone marrow transplantation in critical limb ischemia Tissue Eng Part A 17 2011 243 254
17. D.F. Williams To engineer is to create: the link between engineering and regeneration Trends Biotechnol 24 2006 4 8
18. S. Ghanaati, M.J. Webber, R.E. Unger, C. Orth, J.F. Hulvat, and S.E. Kiehna Dynamic in vivo biocompatibility of angiogenic peptide amphiphile nanofibers Biomaterials 30 2009 6202 6212
19. K. Rajangam, H.A. Behanna, M.J. Hui, X. Han, J.F. Hulvat, and J.W. Lomasney Heparin binding nanostructures to promote growth of blood vessels Nano Lett 6 2006 2086 2090
20. A.D. Rieux, B. Ucakar, B.P. Mupendwa, D. Colau, O. Feron, and P. Carmeliet 3D systems delivering VEGF to promote angiogenesis for tissue engineering J Control Release 150 2010 272 278
21. V. Mironov, V. Kasyanov, and R.R. Markwald Nanotechnology in vascular tissue engineering: from nanoscaffolding towards rapid vessel biofabrication Trends Biotechnol 26 2008 338 344
22. H. Hosseinkhani, M. Hosseinkhani, A. Khademhosseini, H. Kobayashi, and Y. Tabata Enhanced angiogenesis through controlled release of basic fibroblast growth factor from peptide amphiphile for tissue regeneration Biomaterials 27 2006 5836 5844
23. R. Vasita, and D.S. Katti Growth factor-delivery systems for tissue engineering: a materials perspective Expert Rev Med Devices 3 2006 29 47
24. C.V. Bouten, P.Y. Dankers, A. Driessen-Mol, S. Pedron, A.M. Brizard, and F.P. Baaijens Substrates for cardiovascular tissue engineering Adv Drug Delivery Rev 63 2011 221 241
25. J. Xie, X. Li, and Y. Xia Putting electrospun nanofibers to work for biomedical research Macromol Rapid Commun 29 2008 1775 1792
26. G.C. Rutledge, and S.V. Fridrikh Formation of fibers by electrospinning Adv Drug Delivery Rev 59 2007 1384 1391
27. D.E. Heath, J.J. Lannutti, and S.L. Cooper Electrospun scaffold topography affects endothelial cell proliferation, metabolic activity, and morphology J Biomed Mater Res Part A 94 2010 1195 1204
28. L. Liu, and Y.A. Dzenis Analysis of the effects of the residual charge and gap size on electrospun nanofiber alignment in a gap method Nanotechnology 19 2008 355307
29. Z. Ma, W. He, T. Yong, and S. Ramakrishna Grafting of gelatin on electrospun poly(caprolactone) nanofibers to improve endothelial cell spreading and proliferation and to control cell orientation Tissue Eng 11 2005 1149 1158
30. T. Qian, and Y. Wang Micro/nano-fabrication technologies for cell biology Med Biol Eng Comput 48 2010 1023 1032
31. C. Xu Aligned biodegradable nanofibrous structure: a potential scaffold for blood vessel engineering Biomaterials 25 2004 877 886
32. S. Sahoo, L.T. Ang, J.C. Goh, and S. Toh Growth factor delivery through electrospun nanofibers in scaffolds for tissue engineering applications J Biomed Mater Res Part A 93 2009 1539 1550
33. X. Zhang, C.B. Baughman, and D.L. Kaplan In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth Biomaterials 29 2008 2217 2227
34. R. Dersch, T. Liu, A.K. Schaper, A. Greiner, and J.H. Wendorff Electrospun nanofibers: Internal structure and intrinsic orientation J Polym Sci. Part A. Polym Chem 41 2003 545 553
35. M. Khil, S.R. Bhattarai, H. Kim, S. Kim, and K. Lee Novel fabricated matrix via electrospinning for tissue engineering J Biomed Mater Res. Part B. Appl Biomater 72B 2005 117 124
36. A. Theron, E. Zussman, and A.L. Yarin Electrostatic field-assisted alignment of electrospun nanofibres Nanotechnology 12 2001 384 390
37. P. Katta, M. Alessandro, R.D. Ramsier, and C.G. Chase Continuous electrospinning of aligned polymer nanofibers onto a wire drum collector Nano Lett 4 2004 2215 2218
38. D. Li, Y. Wang, and Y. Xia Electrospinning of polymeric and ceramic nanofibers as uniaxially aligned arrays Nano Lett 3 2003 1167 1171
39. B. Sundaray, V. Subramanian, T.S. Natarajan, R. Xiang, C. Chang, and W. Fann Electrospinning of continuous aligned polymer fibers Appl Phys Lett 84 2004 1222 1225
40. R.J. Laham, L. Garcia, D.S. Baim, M. Post, and M. Simons Therapeutic angiogenesis using basic fibroblast growth factor and vascular endothelial growth factor using various delivery strategies Curr Interv Cardiol Rep 1 1999 228 233
41. R.R. Chen, E.A. Silva, W.W. Yuen, and D.J. Mooney Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation Pharm Res 24 2007 258 264
42. F. Gentile, L. Tirinato, E. Battista, F. Causa, C. Liberale, and E.M. di Fabrizio Cells preferentially grow on rough substrates Biomaterials 31 2010 7205 7512
43. B.M. Baker, A.O. Gee, R.B. Metter, A.S. Nathan, R.A. Marklein, and J.A. Burdick The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers Biomaterials 29 2008 2348 2358
44. Hamerly G, Elkan C. Alternatives to the k-Means Algorithm That Find Better Clusterings. Proceedings int'l Conference on information and Knowledge Management 2002:600-607.
45. Zhang B. Generalized K-harmonic means: boosting in unsupervised learning (HP laboratories technical report): Hewlett-Packard laboratories, 2000. Available from: http://www.hpl.hp.com/techreports/2000/HPL-2000-137.html.
46. Platt JC. Probabilities for SV machines in advances in large margin classifiers. In: Smola A, Bartlett P, Scholkopf B, Schuurmans D, editors. Advances in Large Margin Classifiers, MIT Press; 2000. p. 61-74.
47. Medioni G, Mordohai P, Nicolescu M. The tensor voting framework. In: Eduardo Bayro Corrochano, editors. Handbook of Geometric Computing: Applications in Pattern Recognition, Computer Vision, Neural Computing, and Robotics, Springer-Verlag Berlin Heidelberg; 2005. p. 535-68.
48. R. Farra, P. Caliceti, G. Guarnieri, S. Salmaso, M. Carenza, and M. Grassi Temperature-sensitive hydrogels: potential therapeutic applications Am J Drug Delivery 3 2005 239 251
49. S. Young, M. Wong, Y. Tabata, and A.G. Mikos Gelatin as a delivery vehicle for the controlled release of bioactive molecules J Control Release 109 2005 256 274
50. W.J. Li, Y.J. Jiang, and R.S. Tuan Chondrocyte phenotype in engineered fibrous matrix is regulated by fiber size Tissue Eng 12 2006 1775 1785
51. L. Wang, and R. Carrier Biomimetic topography: bioinspired cell culture substrates and scaffolds A. George, Advances in biomimetics 2011 InTech 453
52. Z. Chen, A. Htay, W. Dos Santos, G.T. Gillies, H.L. Fillmore, and M.M. Sholley In vitro angiogenesis by human umbilical vein endothelial cells (HUVEC) induced by three-dimensional co-culture with glioblastoma cells J Neurooncol 92 2009 121 128
53. M. Nakatsu, and C. Hughes Chapter 4. An optimized three-dimensional In vitro model for the analysis of angiogenesis Meth Enzymol 443 2008 65 82
54. B. Bondar, S. Fuchs, A. Motta, C. Migliaresi, and C.J. Kirkpatrick Functionality of endothelial cells on silk fibroin nets: comparative study of micro- and nanometric fibre size Biomaterials 29 2008 561 572