The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers

Biomaterials

Volumn 29, Issue 15, 2008, Pages 2348-2358

  Baker, Brendon M ^a,b   Gee, Albert O ^a   Metter, Robert B ^a,b   Nathan, Ashwin S ^a,b   Marklein, Ross A ^b   Burdick, Jason A ^b   Mauck, Robert L ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cellular infiltration; Electrospinning; Fibrous scaffolds; Mesenchymal stem cells; Tissue engineering

Indexed keywords

ANISOTROPY; ELECTROSPINNING; SCAFFOLDS; TISSUE ENGINEERING;

CELLULAR INFILTRATION; FIBROUS SCAFFOLDS; MESENCHYMAL STEM CELLS;

COMPOSITE MATERIALS;

MACROGOL; POLYCAPROLACTONE; POLYMER;

ANIMAL CELL; ANISOTROPY; ARTICLE; BIOCOMPATIBILITY; CELL INFILTRATION; CONTROLLED STUDY; ELECTROSPINNING; MESENCHYMAL STEM CELL; NONHUMAN; POROSITY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TENSILE STRENGTH; TISSUE ENGINEERING;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIOMECHANICS; CATTLE; CELL MOVEMENT; GUIDED TISSUE REGENERATION; MESENCHYMAL STEM CELLS; MICROSCOPY, ELECTRON, SCANNING; MODELS, BIOLOGICAL; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; POROSITY; TENSILE STRENGTH; TISSUE SCAFFOLDS;

EID: 40649127864     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.01.032     Document Type: Article

References (35)

1. Lynch H.A., Johannessen W., Wu J.P., Jawa A., and Elliott D.M. Effect of fiber orientation and strain rate on the nonlinear uniaxial tensile material properties of tendon. J Biomech Eng 125 5 (2003) 726-731
2. Setton L.A., Guilak F., Hsu E.W., and Vail T.P. Biomechanical factors in tissue engineered meniscal repair. Clin Orthop Relat Res 367 Suppl. (1999) S254-S272
3. Holzapfel G.A., Schulze-Bauer C.A., Feigl G., and Regitnig P. Single lamellar mechanics of the human lumbar anulus fibrosus. Biomech Model Mechanobiol 3 3 (2005) 125-140
4. Newman A.P., Anderson D.R., Daniels A.U., and Dales M.C. Mechanics of the healed meniscus in a canine model. Am J Sports Med 17 2 (1989) 164-175
5. Beredjiklian P.K., Favata M., Cartmell J.S., Flanagan C.L., Crombleholme T.M., and Soslowsky L.J. Regenerative versus reparative healing in tendon: a study of biomechanical and histological properties in fetal sheep. Ann Biomed Eng 31 10 (2003) 1143-1152
6. Reneker D.H., and Chun I. Nanometre diameter fibres of polymer, produced by electrospinning. Nanotechnology 7 (1996) 216-223
7. Courtney T., Sacks M.S., Stankus J., Guan J., and Wagner W.R. Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy. Biomaterials 27 19 (2006) 3631-3638
8. Ayres C., Bowlin G.L., Henderson S.C., Taylor L., Shultz J., Alexander J., et al. Modulation of anisotropy in electrospun tissue-engineering scaffolds: analysis of fiber alignment by the fast Fourier transform. Biomaterials 27 32 (2006) 5524-5534
9. Li W.J., Mauck R.L., and Tuan R.S. Electrospun nanofibrous scaffolds: production, characterization, and applications for tissue engineering and drug delivery. J Biomed Nanotech 1 3 (2005) 259-275
10. Li W.J., Mauck R.L., Cooper J.A., Yuan X., and Tuan R.S. Engineering controllable anisotropy in electrospun biodegradable nanofibrous scaffolds for musculoskeletal tissue engineering. J Biomech 40 8 (2007) 1686-1693
11. Deitzel J.M., Kleinmeyer J., Harris D., and Beck Tan N.C. The effect of processing variables on the morphology of electrospun nanofibers and textiles. Polymer 42 (2001) 261-272
12. Li M., Mondrinos M.J., Gandhi M.R., Ko F.K., Weiss A.S., and Lelkes P.I. Electrospun protein fibers as matrices for tissue engineering. Biomaterials 26 30 (2005) 5999-6008
13. Li W.J., Jiang Y.J., and Tuan R.S. Chondrocyte phenotype in engineered fibrous matrix is regulated by fiber size. Tissue Eng 12 7 (2006) 1775-1785
14. Nerurkar N.L., Elliott D.M., and Mauck R.L. Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering. J Orthop Res 25 8 (2007) 1018-1028
15. Ayres C.E., Bowlin G.L., Pizinger R., Taylor L.T., Keen C.A., and Simpson D.G. Incremental changes in anisotropy induce incremental changes in the material properties of electrospun scaffolds. Acta Biomater 3 5 (2007) 651-661
16. Baker B.M., and Mauck R.L. The effect of nanofiber alignment on the maturation of engineered meniscus constructs. Biomaterials 28 11 (2007) 1967-1977
17. Baker B.M., Nathan A.S., Huffman G.R., and Mauck R.L. Structure-function correlations of young and aged human fibrochondrocyte-seeded engineered meniscus constructs. Trans Orthop Res Soc 33 (2008) 321
18. Stankus J.J., Guan J., Fujimoto K., and Wagner W.R. Microintegrating smooth muscle cells into a biodegradable, elastomeric fiber matrix. Biomaterials 27 5 (2006) 735-744
19. Buttafoco L., Kolkman N.G., Engbers-Buijtenhuijs P., Poot A.A., Dijkstra P.J., Vermes I., et al. Electrospinning of collagen and elastin for tissue engineering applications. Biomaterials 27 5 (2006) 724-734
20. McManus M.C., Boland E.D., Koo H.P., Barnes C.P., Pawlowski K.J., Wnek G.E., et al. Mechanical properties of electrospun fibrinogen structures. Acta Biomater 2 1 (2006) 19-28
21. Telemeco T.A., Ayres C., Bowlin G.L., Wnek G.E., Boland E.D., Cohen N., et al. Regulation of cellular infiltration into tissue engineering scaffolds composed of submicron diameter fibrils produced by electrospinning. Acta Biomater 1 4 (2005) 377-385
22. Matthews J.A., Wnek G.E., Simpson D.G., and Bowlin G.L. Electrospinning of collagen nanofibers. Biomacromolecules 3 2 (2002) 232-238
23. Li W.J., Cooper Jr. J.A., Mauck R.L., and Tuan R.S. Fabrication and characterization of six electrospun poly(alpha-hydroxy ester)-based fibrous scaffolds for tissue engineering applications. Acta Biomater 2 4 (2006) 377-385
24. van Tienen T.G., Heijkants R.G., Buma P., de Groot J.H., Pennings A.J., and Veth R.P. Tissue ingrowth and degradation of two biodegradable porous polymers with different porosities and pore sizes. Biomaterials 23 8 (2002) 1731-1738
25. Pham Q.P., Sharma U., and Mikos A.G. Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration. Biomacromolecules 7 10 (2006) 2796-2805
26. Nam J., Huang Y., Agarwal S., and Lannutti J. Improved cellular infiltration in electrospun fiber via engineered porosity. Tissue Eng 13 9 (2007) 2249-2257
27. Ding B., Kimura E., Sato T., Fujita S., and Shiratori S. Fabrication of blend biodegradable nanofibrous nonwoven mats via multi-jet electrospinning. Polymer 45 6 (2004) 1895-1902
28. Kidoaki S., Kwon I.K., and Matsuda T. Mesoscopic spatial designs of nano- and microfiber meshes for tissue-engineering matrix and scaffold based on newly devised multilayering and mixing electrospinning techniques. Biomaterials 26 1 (2005) 37-46
29. Madhugiri S., Dalton A., Gutierrez J., Ferraris J.P., and Balkus Jr. K.J. Electrospun MEH-PPV/SBA-15 composite nanofibers using a dual syringe method. J Am Chem Soc 125 47 (2003) 14531-14538
30. Johnstone B., Hering T.M., Caplan A.I., Goldberg V.M., and Yoo J.U. In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells. Exp Cell Res 238 (1998) 265-272
31. Caplan A.I. Mesenchymal stem cells. J Orthop Res 9 5 (1991) 641-650
32. Li W.J., Tuli R., Huang X., Laquerriere P., and Tuan R.S. Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold. Biomaterials 26 25 (2005) 5158-5166
33. Costa K.D., Lee E.J., and Holmes J.W. Creating alignment and anisotropy in engineered heart tissue: role of boundary conditions in a model three-dimensional culture system. Tissue Eng 9 4 (2003) 567-577
34. Anderson D.G., Tweedie C.A., Hossain N., Navarro S.M., Brey D.M., Van Vliet K.J., et al. A Combinatorial library of photocrosslinkable and degradable materials. Adv Mater 18 (2006) 2614-2618
35. Tan AR, Ifkovits JL, Baker BM, Brey DM, Mauck RL, Burdick JA. Electrospinning of photocrosslinked and degradable fibrous scaffolds. J Biomed Mater Res, in press [PMID: 18257065].