Electrospun scaffold topography affects endothelial cell proliferation, metabolic activity, and morphology

Journal of Biomedical Materials Research - Part A

Volumn 94, Issue 4, 2010, Pages 1195-1204

  Heath, Daniel E ^a   Lannutti, John J ^a   Cooper, Stuart L ^a  

^a The Ohio State University   (United States)

Author keywords

Biomimetic material; Electrospinning; Endothelial cell; Scaffold; Terpolymer

Indexed keywords

ADHERENT CELLS; ALIGNED FIBERS; CELLULAR PROLIFERATIONS; ELECTROSPUNS; ENZYMATIC ACTIVITIES; FIBER ALIGNMENT; FIBROUS SCAFFOLDS; FUSED-FIBER; GLASS TRANSITION TEMPERATURE; GLASSY MATERIALS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; IN-CELL; METABOLIC ACTIVITY; NUMBER AVERAGE MOLECULAR WEIGHT; POLYMER CHAINS; ROTATING MANDREL; ROTATION SPEED; RUBBERY MATERIALS; STATIC CONDITIONS; VOID SPACE;

ALIGNMENT; BIOLOGICAL MATERIALS; BIOMIMETICS; CELL PROLIFERATION; ELECTROSPINNING; ENDOTHELIAL CELLS; FIBERS; GLASS TRANSITION; METABOLISM; MORPHOLOGY; ROTATION; SELF ASSEMBLY;

SCAFFOLDS;

BIOMEDICAL AND DENTAL MATERIALS; CELL SCAFFOLD; METHACRYLIC TERPOLYMER; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL ELONGATION; CELL PROLIFERATION; ELECTROSPINNING; ENDOTHELIUM CELL; ENZYME ACTIVITY; GLASS TRANSITION TEMPERATURE; HUMAN; HUMAN CELL; METABOLISM; MOLECULAR WEIGHT; MORPHOLOGY; UMBILICAL VEIN;

CELL ADHESION; CELL PROLIFERATION; CELL SHAPE; ELASTIC MODULUS; ENDOTHELIAL CELLS; GLASS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; MOLECULAR WEIGHT; POLYMERS; POROSITY; SURFACE PROPERTIES; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TRANSITION TEMPERATURE; UMBILICAL VEINS;

EID: 77956480227     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32802     Document Type: Article

References (38)

1. Ratner BD, Hoffman, AS, Schoen FJ, Lemons JE. Biomaterials Science, 2nd ed. San Diego, CA: Elsevier Academic Press; 2004.
2. Nam YS, Park TG. Porous biodegradable polymeric tissue scaffolds prepared by thermally induced phase separation. J Biomed Mater Res 1999;47:8-17. (Pubitemid 29344964)
3. Barry JJA, Gidda HS, Scotchford CA, Howdle SM. Porous methacrylate scaffolds: supercritical fluid fabrication and in vitro chondrocyte response. Biomaterials 2004;25:3559-3568.
4. Lee SH, Kim BS, Kim SH, Choi SW, Jeong SI, Kwon IK, Kang SW, Nikolvski J, Mooney DJ, Han, YK, Kim YH. Elastic biodegradable poly(glycolide-co- caprolactone) scaffold for tissue engineering. J Biomed Mater Res A 2003:66;29-37.
5. Vernon RB, Gooden MD, Lara SL, Wight TN. Microgrooved fibrillar collagen membranes as scaffolds for cell support and alignment. Biomaterials 2005;26:3131-3140.
6. Kwon IK, Kidoaki S, Matsuds T. Electrospun nano- to microfiber fabrics made of biodegradable copolyesters: Structural characteristics, mechanical properties and cell adhesion potential. Biomaterials 2005;26:3929-3939.
7. Formhals A. Process and apparatus for preparing artificial threads. US Patent No. 1,975,504, 1934.
8. Gupta P, Elkins C, Long T, Wilkes GL. Electrospinning of linear homopolymers of poly(methyl methacrylate): Exploring relationships between fiber formation, viscosity, molecular weight and concentration in a good solvent. Polymer 2005;46:4799-4810. (Pubitemid 40688482)
9. Lee KH, Kim HY, La YM, Lee DR, Sung NH. Influence of a mixed solvent with tetrahydrofuran and N,N-dimethylformamide on electrospun poly(vinyl chloride) nonwoven mats. J Polymer Sci 2002;40B:2259-2268.
10. Li WJ, Laurencin CT, Caterson EJ, Tuan RS, Ko FK. Electrospun nanofibrous structure: A novel scaffold for tissue engineering. J Biomed Mater Res 2002;60:613-621.
11. Shin M, Yoshimoto H, Vacanti J. In vivo bone tissue engineering using mesenchymal stem cells on a novel electrospun nanofibrous scaffold. Tissue Eng 2004;10:33-41.
12. Matthews JA, Wnek GE, Simpson DG, Bowlin GL. Electrospinning of collagen nanofibers. Biomacromolecules 2002;3:232-238.
13. Buttafoco L, Kolkman NG, Engbers-Buijtenhuijs P, Poot AA, Dijkstra PJ, Vermes I, Feijen J. Electrospinning of collagen and elastin for tissue engineering applications. Biomaterials 2006;27:724-734.
14. Ji Y, Ghosh K, Shu XZ, Li B, Sokolov JC, Prestwich GD, Clark RAF, Rafailovich MH. Electrospun three-dimensional hyaluronic acid nanofibrous scaffolds. Biomaterials 2006;27:3782-3792.
15. Jin HJ, Chen J, Karageorgiou V, Altman GH, Kaplan DL. Human bone marrow stromal cell responses on electrospun silk fibroin mats. Biomaterials 2004;25:1039-1047.
16. Xu CY, Inai R, Ramakrishna S. Aligned biodegradable nanofibrous structures: A potential scaffold for blood vessel engineering. Biomaterials 2004;25:877-886. (Pubitemid 37371995)
17. Li D, Wang Y, Xia Y. Electrospinning nanofibers as uniaxially aligned arrays and layer-by-layer stacked films. Adv Mater 2004;16:361-366.
18. Bornat A. Production of electrostatically spun products. US Patent No. 4,689,186, 1987.
19. Heath DH, Cooper SL. Interaction of endothelial cells with methacrylic terpolymer biomaterials. J Biomed Mater Res B Appl Biomater 2010;92:289-297.
20. Nam J, Huang Y, Agarwal S, Lannutti J. Materials selection and residual solvent retention in biodegradable electrospun fibers. J Appl Polymer Sci 2008;107:1547-1554.
21. Waite JH, Lichtenegger HC, Stucky GD, Hansma P. Exploring molecular and mechanical gradients in structural bioscaffolds. Biochemistry 2004;43:7653-7662.
22. Trubel W, Schima H, Moritz A, Raderer F, Windisch A, Ullrich R, Windberger U, Losert U, Polterauer P. Compliance mismatch and formation of distal anastomotic intimal hyperplasia in externally stiffened and lumen-adapted venous grafts. Eur J Vasc Endovasc Surg 1995;10:415-423.
23. Fussell GW, Cooper SL. Endothelial cell adhesion on RGD-containing methacrylate terpolymers. J BiomedMater Res 2004;70A:265-273. (Pubitemid 38988757)
24. Fussell GW, Cooper SL. Synthesis and characterization of acrylic terpolymers with RGD peptides for biomedical applications. Biomaterials 2004;25:2971-2978.
25. Veleva AN, Khan SA, Cooper SL. Oxidative and hydrolytic stability of a novel acrylic terpolymer for biomedical applications. J Biomed Mater Rev A 2005;74:117-123.
26. Ramakrishna S, Fujihara K, Teo W, Lim T, Ma Z. An Introduction to Electrospinning and Nanofibers. Toh Tuck Link, Singapore: World Scientific Publishing Company; 2005.
27. He W, Yong T, Ma ZW, Inai R, Teo WE, Ramakrishna S. Biodegradable polymer nanofiber mesh to maintain functions of endothelial cells. Tissue Eng 2006;12:2457-2466.
28. Ma ZW, Kotaki M, Inai R, Ramakrishna S. Potential of nanofiber matrix as tissue-engineering scaffolds. Tissue Eng 2005;11:101-109.
29. Yang F, Murugan R, Wang S, Ramakrishna S. Electrospinning of nano/micro scale poly(L-lactic acid) aligned fibers and their potential in neural tissue engineering. Biomaterials 2005;26:2603-2610. (Pubitemid 39600712)
30. Billmeyer FW. Text Book of Polymer Science, 2nd ed. New York: John Wiley and Sons Inc.; 1984.
31. Han Z, Kong H, Meng J, Wang C, Xie s, Xu H. Electrospun aligned nanofibrous scaffolds of carbon nanotubes-polyurethane composite for endothelial cells. J Nanosci Nanotechnol 2009;9:1400-1402.
32. Ma Z, Kotaki M, Inai R, Ramakrishna S. Potential of nanofibers matrix as tissue-engineering scaffolds. Tissue Eng 2005;11:101-109.
33. Murugan R, Ramadrishna S. Design strategies of tissue engineering scaffolds with controlled fiber orientation. Tissue Eng 2007;13:1845-1866.
34. Vracko R, Benditt E. Capillary basal lamina thickening: its relationship to endothelial cell death and replacement. J Cell Biol 1970;47:281-285.
35. Viggers R, Wechezak A, Sauvage L. An apparatus to study the response of cultured endothelium to shear stress. J Biomech Eng 1986;108:332-337. (Pubitemid 17189365)
36. Levesque M, Liepsch D, Moravec S, Nerem R. Correlation of endothelial cell shape and wall shear stress in a stenosed dog aorta. Arteriosclerosis 1986;6:220-229.
37. Inoguchi H, Tanaka T, Maehara Y, Matsuda T. The effect of gradually graded shear stress on the morphological integrity of HUVEC-seeded compliant small diameter vascular graft. Biomaterials 2007;28:486-495.
38. Shadwick RE. Mechanical design in arteries. J Exp Biol 1999;202:3305-3313.