Screening, identification, and characterization of mechanistically diverse inhibitors of the Mycobacterium tuberculosis enzyme, pantothenate kinase (CoaA)

Journal of Biomolecular Screening

Volumn 17, Issue 3, 2012, Pages 293-302

  Venkatraman, Janani ^a   Bhat, Jyothi ^a   Solapure, Suresh M ^a   Sandesh, Jatheendranath ^a   Sarkar, Debasmita ^a   Aishwarya, Sundaram ^a   Mukherjee, Kakoli ^a   Datta, Santanu ^a   Malolanarasimhan, Krishnan ^a   Bandodkar, Balachandra ^a   Das, Kaveri S ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

CoaA; MoI; Tm shift; tuberculosis

Indexed keywords

BACTERIAL ENZYME; MYCOBACTERIUM TUBERCULOSIS PANTOTHENATE KINASE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME SUBSTRATE; HIGH THROUGHPUT SCREENING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN STABILITY; THERMOSTABILITY;

BIOLOGICAL ASSAY; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HIGH-THROUGHPUT SCREENING ASSAYS; MYCOBACTERIUM TUBERCULOSIS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

EID: 84859054747     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111423069     Document Type: Article

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