A 2a adenosine receptor mediates HepG2 cell apoptosis by downregulating Bcl-X L expression and upregulating bid expression

Journal of Cellular Biochemistry

Volumn 113, Issue 5, 2012, Pages 1766-1775

  Tamura, Kunihiro ^a   Kanno, Takeshi ^a   Fujita, Yumiko ^a   Gotoh, Akinobu ^a   Nakano, Takashi ^a   Nishizaki, Tomoyuki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

A 2a ADENOSINE RECEPTOR; APOPTOSIS; Bcl X L; Bid; HepG2 CELL

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR ANTAGONIST; CASPASE 3; CASPASE 9; CYTOCHROME C; MESSENGER RNA; PROTEIN BCL XL; PROTEIN BID;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL STRAIN HEPG2; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ASSAY; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ADENOSINE; ADENOSINE A2 RECEPTOR AGONISTS; APOPTOSIS; BASE SEQUENCE; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASES; CYTOCHROMES C; DOWN-REGULATION; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HEPATOCYTES; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; RECEPTOR, ADENOSINE A2A; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84859032781     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24048     Document Type: Article

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