Activation of Protein Kinase A and Atypical Protein Kinase C by A 2A Adenosine Receptors Antagonizes Apoptosis Due to Serum Deprivation in PC12 Cells

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13838-13846

  Huang, Nai Kuei ^a   Lin, Ya Wen ^a   Huang, Chuen Lin ^a   Messing, Robert O ^b,c   Chern, Yijuang ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DATA ACQUISITION; PROTEINS;

SERUM DEPRIVATION;

BIOCHEMISTRY;

2 MORPHOLINO 8 PHENYLCHROMONE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 8 (3 CHLOROSTYRYL)CAFFEINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; BISINDOLYLMALEIMIDE; CALYCULIN A; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; KT 5720; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NERVE GROWTH FACTOR; OKADAIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE C; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ADENOSINE; ADENOSINE RECEPTOR; AKT1 PROTEIN, RAT; CHROMONE DERIVATIVE; COLORING AGENT; DNA FRAGMENT; DRUG DERIVATIVE; ENZYME INHIBITOR; MORPHOLINE DERIVATIVE; ONCOPROTEIN; PHENETHYLAMINE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL STRAIN; ENZYME ACTIVATION; ENZYME ASSAY; FLOW CYTOMETRY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CELL MEMBRANE; CELL NUCLEUS; CELL SURVIVAL; CULTURE MEDIUM; CYTOSOL; DOMINANT GENE; DOSE RESPONSE; DOWN REGULATION; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; METABOLISM; TIME; WESTERN BLOTTING;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOSINE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL MEMBRANE; CELL NUCLEUS; CELL SURVIVAL; CHROMONES; COLORING AGENTS; CULTURE MEDIA, SERUM-FREE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOSOL; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; FORSKOLIN; GENES, DOMINANT; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; MORPHOLINES; PC12 CELLS; PHENETHYLAMINES; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTOR, ADENOSINE A2A; RECEPTORS, PURINERGIC P1; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS; TRANSFECTION;

EID: 0035958067     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008589200     Document Type: Article

References (48)

1. Daval, J.-L., Nehlig, A., and Nicolas, F. (1991) Life Sci. 49, 1435-1453
2. Olah, M. E., and Stiles, G. L. (1996) Annu. Rev. Pharmacol. Toxicol. 35, 581-606
3. Chern, Y. J., King, K., Lai, H.-L., and Lai, H. T. (1992) Biochem. Biophys. Res. Commun. 185, 304-309
4. Chu, Y.-Y., Tu, K.-H., Lee, Y.-C., Kuo, Z.-J., Lai, H.-L., and Chern, Y. (1996) DNA Cell Biol. 15, 329-337
5. Ferre, S., O'Connor, W. T., Fuxe, K., and Ungerstedt, U. (1993) J. Neurosci. 13, 5402-5406
6. Rosin, D. L., Robeva, A., Woodard, R. L., Guyenet, P. G., and Linden, J. (1998) J. Comp. Neurol. 401, 163-186
7. Richardson, P. J., Kase, H., and Jenner, P. G. (1997) Trends Pharmacol. Sci. 18, 338-344
8. Sebastiao, A. M., and Ribeiro, J. A. (1996) Prog. Neurobiol. 48, 167-189
9. Kobayashi, S., and Millhorn, D. E. (1999) J. Biol. Chem. 294, 20358-20365
10. Walker, B. A. M., Rocchini, C., Boone, R. H., Ip, S., and Jacobson, M. A. (1997) J. Immunol. 158, 2926-2931
11. Jones, P., A., Smith, R. A., and Stone, T. W. (1998) Neuroscience 85, 229-237
12. Xia Z., Dickens, M., Raingeaud, J., and Greenberg, M. E. (1995) Science 270, 1326-1331
13. Chern, Y., Chiou, J.-Y., Lai, H.-L., and Tsai, M.-H. (1995) Mol. Pharmacol. 48, 1-8
14. Lai, H. L., Yang, T. H., Messing, R. O., Chin, Y. H., Lin, S. C., and Chern, Y. (1997) J. Biol. Chem. 272, 4970-4977
15. Ginty, D. D., Glowacka, D., DeFranco, C., and Wagner, J. A. (1991) J. Biol. Chem. 266, 15325-15333
16. Gerstin, E., Jr., McMahon, T., Dadgar, J., and Messing, R. O. (1998) J. Biol. Chem. 273, 16409-16414
17. Wooten, M. W., Seibenhener, M. L., Boone, R. H., Matthews, L. H., Zhou, G., and Coleman, E. S. (1996) J. Neurochem. 67, 1023-1031
18. Zhou, G., Seibenhener, M. L., and Wooten, M. W. (1997) J. Biol. Chem. 272, 3110-31137
19. Revan, S., Montesinos, M. C., Naime, D., Landau, S., and Cronstein, B. N. (1996) J. Biol. Chem. 271, 17114-17118
20. Seidel, M. G., Klinger, M., Freissmuth, M., and Holler, C. (1999) J. Biol. Chem. 274, 25833-25841
21. Creedon, D. J., Johnson, E. M., Jr., and Lawrence, J. C., Jr. (1996) J. Biol. Chem. 271, 20713-20718
22. Wang, Y. M., Seibenhener, M. L., Vandenplas, M. L., and Wooten, M. W. (1999) J. Neurosci. Res. 55, 293-302
23. Schonwasser, D. C., Marais, R. M., Marshall, C. J., and Parker, P. J. (1998) Mol. Cell. Biol. 18, 790-798
24. Neri, L. M., Martelli, A. M., Borgatti, P., Colamussi, M. L., Marchisio, M., and Capitani, A. S. (1999) FASEB J. 13, 2299-2310
25. Datta, S. R., Brunet, A., and Greenberg, M. E. (1999) Genes Dev. 13, 2905-2927
26. Downward, J. (1998) Cell Biol. 10, 262-267
27. Toker, A., and Newton, A. C. (2000) J. Biol. Chem. 275, 8271-8274
28. Cichy, S. B., Uddin, S., Danilkovich, A., Guo, S., Klippel, A., and Unterman, T. G. (1998) J. Biol. Chem. 273, 6482-6487
29. Rukenstein, A., Rydel, R. E., and Greene, L. A. (1991) J. Neurosci. 11, 2552-2563
30. Lambeng, N., Michel, P. P., Brugg, B., Agid, Y., and Ruberg, M. (1999) Brain Res. 821, 60-68
31. Toullec, D., Pianetti, P., Coste, H., Bellevergue, P., Grand-Perret, T., Ajakane, M., Baudet, V., Boissin, P., Boursier, E., Loriolle, F., Duhamel, L., Charon, D., and Kirlovsky, J. (1991) J. Biol. Chem. 266, 15771-15781
32. Ali, H., Fisher, I., Haribabu, B., Richardson, R. M., and Snyderman, R. (1998) J. Biol. Chem. 272, 11706-11709
33. Taylor, S. C., Green, K. N., Carpenter, E., and Peer, C. (2000) J. Biol. Chem. 275, 26786-26791
34. Liu, H., Force, T., and Bloch, K. D. (1997) J. Biol. Chem. 272, 6038-6043
35. Wooten, M. W., Zhou, G., Wooten, M. C., and Seibenhener, M. L. (1997) J. Neurosci. Res. 49, 393-403
36. Berra, E., Municio, M. M., Sanz, L., Frutos, S., Diaz-Meco, M. T., and Moscat, J. (1997) Mol. Cell. Biol. 17, 4346-4354
37. Lallena, M. J., Diaz-Meco, M. T., Bern, G., Paya, C. V., and Moscat, J. (1999) Mol. Cell. Biol. 19, 2180-2188
38. Murray, N. R., and Fields, A. P. (1997) J. Biol. Chem. 272, 27521-27524
39. Moule, S. K., Welsh, G. I., Edgell, N. J., Foulstone, E. J., Proud, C. G., Denton, R. M. (1997) J. Biol. Chem. 272, 7713-7719
40. Polakiewicz, R. D., Schieferl, S. M., Gingras, A. C., Sonenberg, N., and Comb, M. J. (1998) J. Biol. Chem. 273, 23534-2341
41. Klesse, L. J., Meyers, K. A., Marshall, C. J., and Parada, L. F. (1999) Oncogene 18, 2055-2068
42. Chou, M. M., Hou, W., Johnson, J., Graham, L. K., Lee, M. H., Chen, C. S., Newton, A. C., Schaffhausen, B. S., and Toker, A. (1998) Curr. Biol. 8, 1069-1077
43. Crowder, R. J., and Freeman, R. S. (1998) J. Neurosci. 18, 2933-2943
44. Crowder, R. J., and Freeman, R. S. (1999) J. Neurochem. 73, 466-475
45. Millward, T. A., Zolnierowicz, S., and Hemmings, B. A. (1999) Trends Biochem. Sci. 24, 186-191
46. Francois, F., and Grimes, M. L. (1999) J. Neurochem. 73, 1773-1776
47. Dixon., A. K., Gubitz, A. K., Sirinathsinghji, D. J. S., Richardson, P. J., and Freeman, T. C. (1996) Br. J. Pharmacol. 118, 1461-1468
48. Li, Y., S., Shyy, J. Y. J., Li, S., Lee, J., Su, B., Karin, M., and Chien, S. (1996) Mol. Cell. Biol. 16, 5947-5954