-
1
-
-
0033600187
-
Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex
-
DOI 10.1006/bbrc.1999.0894
-
Suetsugu, S., Miki, H., and Takenawa, T. (1999) Identification of two human WAVE/SCAR homologues as general actin regulatory molecules that associate with the Arp2/3 complex. Biochem. Biophys. Res. Commun. 260, 296-302 (Pubitemid 29351823)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.260
, Issue.1
, pp. 296-302
-
-
Suetsugu, S.1
Miki, H.2
Takenawa, T.3
-
2
-
-
20444435118
-
WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase
-
DOI 10.1074/jbc.M500503200
-
Sossey-Alaoui, K., Li, X., Ranalli, T. A., and Cowell JK. (2005) WAVE3- mediated cell migration and lamellipodia formation are regulated down-stream of phosphatidylinositol 3-kinase. J. Biol. Chem. 280, 21748-21755 (Pubitemid 40827822)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.23
, pp. 21748-21755
-
-
Sossey-Alaoui, K.1
Li, X.2
Ranalli, T.A.3
Cowell, J.K.4
-
3
-
-
77957239866
-
Inactivation of the WASF3 gene in prostate cancer cells leads to suppression of tumorigenicity and metastases
-
Teng, Y., Ren, M. Q., Cheney, R., Sharma, S., and Cowell, J. K. (2010) Inactivation of the WASF3 gene in prostate cancer cells leads to suppression of tumorigenicity and metastases. Br. J. Cancer 103, 1066-1075
-
(2010)
Br. J. Cancer
, vol.103
, pp. 1066-1075
-
-
Teng, Y.1
Ren, M.Q.2
Cheney, R.3
Sharma, S.4
Cowell, J.K.5
-
4
-
-
34447326992
-
Down-regulation of WAVE3, a metastasis promoter gene, inhibits invasion and metastasis of breast cancer cells
-
DOI 10.2353/ajpath.2007.060975
-
Sossey-Alaoui, K., Safina, A., Li, X., Vaughan, M. M., Hicks, D. G., Bakin, A. V., and Cowell, J. K. (2007) Down-regulation of WAVE3, a metastasis promoter gene, inhibits invasion and metastasis of breast cancer cells. Am. J. Pathol. 170, 2112-2121 (Pubitemid 47339283)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.6
, pp. 2112-2121
-
-
Sossey-Alaoui, K.1
Safina, A.2
Li, X.3
Vaughan, M.M.4
Hicks, D.G.5
Bakin, A.V.6
Cowell, J.K.7
-
5
-
-
84855162544
-
Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells
-
Teng, Y., Liu, M., and Cowell, J. K. (2011) Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells. Int. J. Cancer 129, 2825-2835
-
(2011)
Int. J. Cancer
, vol.129
, pp. 2825-2835
-
-
Teng, Y.1
Liu, M.2
Cowell, J.K.3
-
6
-
-
0037102301
-
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
-
Eden, S., Rohatgi, R., Podtelejnikov, A. V., Mann, M., and Kirschner, M. W. (2002) Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck. Nature 418, 790-793
-
(2002)
Nature
, vol.418
, pp. 790-793
-
-
Eden, S.1
Rohatgi, R.2
Podtelejnikov, A.V.3
Mann, M.4
Kirschner, M.W.5
-
7
-
-
1842562381
-
Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation
-
DOI 10.1038/sj.emboj.7600084
-
Steffen, A., Rottner, K., Ehinger, J., Innocenti, M., Scita, G., Wehland, J., and Stradal, T. E. (2004) Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation. EMBO J. 23, 749-759 (Pubitemid 38418742)
-
(2004)
EMBO Journal
, vol.23
, Issue.4
, pp. 749-759
-
-
Steffen, A.1
Rottner, K.2
Ehinger, J.3
Innocenti, M.4
Scita, G.5
Wehland, J.6
Stradal, T.E.B.7
-
8
-
-
0037040541
-
Protein folding. Molecular chaperones in the cytosol: From nascent chain to folded protein
-
DOI 10.1126/science.1068408
-
Hartl, F. U., and Hayer-Hartl, M. (2002) Molecular chaperones in the cytosol: From nascent chain to folded protein. Science 295, 1852-1858 (Pubitemid 34214115)
-
(2002)
Science
, vol.295
, Issue.5561
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
9
-
-
17044387386
-
Hsp70 chaperones: Cellular functions and molecular mechanism
-
Mayer, M. P., and Bukau, B. (2005) Hsp70 chaperones: Cellular functions and molecular mechanism. Cell Mol. Life Sci. 62, 670-684
-
(2005)
Cell Mol. Life Sci.
, vol.62
, pp. 670-684
-
-
Mayer, M.P.1
Bukau, B.2
-
10
-
-
32944454483
-
Targeting heat shock response to sensitize cancer cells to proteasome and Hsp90 inhibitors
-
DOI 10.1158/0008-5472.CAN-05-3692
-
Zaarur, N., Gabai, V. L., Porco, J. A., Jr., Calderwood, S., and Sherman, M. Y. (2006) Targeting heat shock response to sensitize cancer cells to proteasome and Hsp90 inhibitors. Cancer Res. 66, 1783-1791 (Pubitemid 43259964)
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1783-1791
-
-
Zaarur, N.1
Gabai, V.L.2
Porco Jr., J.A.3
Calderwood, S.4
Sherman, M.Y.5
-
11
-
-
58249110557
-
Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells
-
Gabai, V. L., Yaglom, J. A., Waldman, T., and Sherman, M. Y. (2009) Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells. Mol. Cell Biol. 29, 559-569
-
(2009)
Mol. Cell Biol.
, vol.29
, pp. 559-569
-
-
Gabai, V.L.1
Yaglom, J.A.2
Waldman, T.3
Sherman, M.Y.4
-
12
-
-
0037108887
-
Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search
-
DOI 10.1021/ac025747h
-
Keller, A., Nesvizhskii, A. I., Kolker, E., and Aebersold, R. (2002) Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal. Chem. 74, 5383-5392 (Pubitemid 35215372)
-
(2002)
Analytical Chemistry
, vol.74
, Issue.20
, pp. 5383-5392
-
-
Keller, A.1
Nesvizhskii, A.I.2
Kolker, E.3
Aebersold, R.4
-
13
-
-
0042338362
-
A statistical model for identifying proteins by tandem mass spectrometry
-
DOI 10.1021/ac0341261
-
Nesvizhskii, A. I., Keller, A., Kolker, E., and Aebersold, R. (2003) A statistical model for identifying proteins by tandem mass spectrometry. Anal. Chem. 75, 4646-4658 (Pubitemid 37082259)
-
(2003)
Analytical Chemistry
, vol.75
, Issue.17
, pp. 4646-4658
-
-
Nesvizhskii, A.I.1
Keller, A.2
Kolker, E.3
Aebersold, R.4
-
14
-
-
25844519550
-
HSP90 and the chaperoning of cancer
-
DOI 10.1038/nrc1716
-
Whitesell, L., and Lindquist, S. L. (2005) HSP90 and the chaperoning of cancer. Nat. Rev. Cancer 5, 761-772 (Pubitemid 41400776)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.10
, pp. 761-772
-
-
Whitesell, L.1
Lindquist, S.L.2
-
15
-
-
33645470397
-
Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis
-
Sanderson, S., Valenti, M., Gowan, S., Patterson, L., Ahmad, Z., Workman, P., and Eccles, S. A. (2006) Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis. Mol. Cancer Ther. 5, 522-532
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 522-532
-
-
Sanderson, S.1
Valenti, M.2
Gowan, S.3
Patterson, L.4
Ahmad, Z.5
Workman, P.6
Eccles, S.A.7
-
16
-
-
56449114760
-
17-Allylamino-17-demethoxygeldanamycin down-regulates hyaluronic acid-induced glioma invasion by blocking matrix metalloproteinase-9 secretion
-
Kim, M. S., Kwak, H. J., Lee, J. W., Kim, H. J., Park, M. J., Park, J. B., Choi, K. H., Yoo, H., Shin, S. H., Shin, W. S., Song, E. S., and Lee, S. H. (2008) 17-Allylamino-17-demethoxygeldanamycin down-regulates hyaluronic acid-induced glioma invasion by blocking matrix metalloproteinase-9 secretion. Mol. Cancer Res. 6, 1657-1665
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 1657-1665
-
-
Kim, M.S.1
Kwak, H.J.2
Lee, J.W.3
Kim, H.J.4
Park, M.J.5
Park, J.B.6
Choi, K.H.7
Yoo, H.8
Shin, S.H.9
Shin, W.S.10
Song, E.S.11
Lee, S.H.12
-
17
-
-
78650734840
-
HSP90 modulates actin dynamics: Inhibition of HSP90 leads to decreased cell motility and impairs invasion
-
Taiyab, A., and Rao, ChM. (2011) HSP90 modulates actin dynamics: Inhibition of HSP90 leads to decreased cell motility and impairs invasion. Biochim. Biophys. Acta 1813, 213-221
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 213-221
-
-
Taiyab, A.1
Rao, Ch.M.2
-
18
-
-
28544433004
-
Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin
-
DOI 10.1158/0008-5472.CAN-05-1799
-
Guo, F., Rocha, K., Bali, P., Pranpat, M., Fiskus, W., Boyapalle, S., Kumaraswamy, S., Balasis, M., Greedy, B., Armitage, E. S., Lawrence, N., and Bhalla, K. (2005) Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin. Cancer Res. 65, 10536-10544 (Pubitemid 41743748)
-
(2005)
Cancer Research
, vol.65
, Issue.22
, pp. 10536-10544
-
-
Guo, F.1
Rocha, K.2
Bali, P.3
Pranpat, M.4
Fiskus, W.5
Boyapalle, S.6
Kumaraswamy, S.7
Balasis, M.8
Greedy, B.9
Armitage, E.S.M.10
Lawrence, N.11
Bhalla, K.12
-
19
-
-
0034711270
-
The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone
-
DOI 10.1074/jbc.M003701200
-
Marcu, M. G., Chadli, A., Bouhouche, I., Catelli, M., and Neckers, L. M. (2000) The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone. J. Biol. Chem. 275, 37181-37186 (Pubitemid 32002137)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.47
, pp. 37181-37186
-
-
Marcu, M.G.1
Chadli, A.2
Bouhouche, I.3
Catelli, M.4
Neckers, L.M.5
-
20
-
-
0038730655
-
Comparative analysis of the ATP-binding sites of Hsp90 by nucleotide affinity cleavage: A distinct nucleotide specificity of the C-terminal ATP-binding site
-
DOI 10.1046/j.1432-1033.2003.03610.x
-
Soti, C., Vermes, A., Haystead, T. A., and Csermely, P. (2003) Comparative analysis of the ATP-binding sites of Hsp90 by nucleotide affinity cleavage: a distinct nucleotide specificity of the C-terminal ATP-binding site. Eur. J. Biochem. 270, 2421-2428 (Pubitemid 36645360)
-
(2003)
European Journal of Biochemistry
, vol.270
, Issue.11
, pp. 2421-2428
-
-
Soti, C.1
Vermes, A.2
Haystead, T.A.J.3
Csermely, P.4
-
21
-
-
34548825949
-
c-Abl-mediated phosphorylation of WAVE3 is required for lamellipodia formation and cell migration
-
DOI 10.1074/jbc.M701484200
-
Sossey-Alaoui, K., Li, X., and Cowell, J. K. (2007) c-Abl-mediated phosphorylation of WAVE3 is required for lamellipodia formation and cell migration. J. Biol. Chem. 282, 26257-26265 (Pubitemid 47443811)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.36
, pp. 26257-26265
-
-
Sossey-Alaoui, K.1
Li, X.2
Cowell, J.K.3
-
22
-
-
0033863883
-
The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210(bcr-abl) and v-src proteins before their degradation by the proteasome
-
An, W. G., Schulte, T. W., and Neckers, L. M. (2000) The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome. Cell Growth Differ. 11, 355-360 (Pubitemid 30619563)
-
(2000)
Cell Growth and Differentiation
, vol.11
, Issue.7
, pp. 355-360
-
-
An, W.G.1
Schulte, T.W.2
Neckers, L.M.3
-
23
-
-
0025303147
-
Interaction of Hsp 70 with newly synthesized proteins: Implications for protein folding and assembly
-
Beckmann, R. P., Mizzen, L. E., and Welch, W. J. (1990) Interaction of Hsp 70 with newly synthesized proteins: Implications for protein folding and assembly. Science 248, 850-854
-
(1990)
Science
, vol.248
, pp. 850-854
-
-
Beckmann, R.P.1
Mizzen, L.E.2
Welch, W.J.3
-
24
-
-
0024298706
-
70K heat shock related proteins stimulate protein translocation into microsomes
-
Chirico, W. J., Waters, M. G., and Blobel, G. (1988) 70K heat shock related proteins stimulate protein translocation into microsomes. Nature 332, 805-810
-
(1988)
Nature
, vol.332
, pp. 805-810
-
-
Chirico, W.J.1
Waters, M.G.2
Blobel, G.3
-
25
-
-
0024975155
-
A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins
-
Chiang, H. L., Terlecky, S. R., Plant, C. P., and Dice, J. F. (1989) A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins. Science 246, 382-385
-
(1989)
Science
, vol.246
, pp. 382-385
-
-
Chiang, H.L.1
Terlecky, S.R.2
Plant, C.P.3
Dice, J.F.4
-
26
-
-
0037099080
-
The cellular fate of mutant rhodopsin: Quality control, degradation, and aggresome formation
-
Saliba, R. S., Munro, P. M., Luthert, P. J., and Cheetham, M. E. (2002) The cellular fate of mutant rhodopsin: Quality control, degradation, and aggresome formation. J. Cell Sci. 115, 2907-2918
-
(2002)
J. Cell Sci.
, vol.115
, pp. 2907-2918
-
-
Saliba, R.S.1
Munro, P.M.2
Luthert, P.J.3
Cheetham, M.E.4
-
27
-
-
0034212740
-
Benzylidene lactam compound, KNK437, a novel inhibitor of acquisition of thermotolerance and heat shock protein induction in human colon carcinoma cells
-
Yokota, S., Kitahara, M., and Nagata, K. (2000) Benzylidene lactam compound, KNK437, a novel inhibitor of acquisition of thermotolerance and heat shock protein induction in human colon carcinoma cells. Cancer Res. 60, 2942-2948 (Pubitemid 30395819)
-
(2000)
Cancer Research
, vol.60
, Issue.11
, pp. 2942-2948
-
-
Yokota, S.-I.1
Kitahara, M.2
Nagata, K.3
-
28
-
-
0025777354
-
Heat shock, stress proteins, chaperones, and proteotoxicity
-
Hightower, L. E. (1991) Heat shock, stress proteins, chaperones, and proteotoxicity. Cell 66, 191-197
-
(1991)
Cell
, vol.66
, pp. 191-197
-
-
Hightower, L.E.1
-
29
-
-
70349768075
-
A small molecule inhibitor of inducible heat shock protein 70
-
Leu, J. I., Pimkina, J., Frank, A., Murphy, M. E., and George, D. L. (2009) A small molecule inhibitor of inducible heat shock protein 70. Mol. Cell 36, 15-27
-
(2009)
Mol. Cell
, vol.36
, pp. 15-27
-
-
Leu, J.I.1
Pimkina, J.2
Frank, A.3
Murphy, M.E.4
George, D.L.5
-
30
-
-
77956825499
-
Germ cell-specific heat shock protein 70-2 is expressed in cervical carcinoma and is involved in the growth, migration, and invasion of cervical cells
-
Garg, M., Kanojia, D., Saini, S., Suri, S., Gupta, A., Surolia, A., and Suri, A. (2010) Germ cell-specific heat shock protein 70-2 is expressed in cervical carcinoma and is involved in the growth, migration, and invasion of cervical cells. Cancer 116, 3785-3796
-
(2010)
Cancer
, vol.116
, pp. 3785-3796
-
-
Garg, M.1
Kanojia, D.2
Saini, S.3
Suri, S.4
Gupta, A.5
Surolia, A.6
Suri, A.7
-
31
-
-
71049173726
-
Heat shock protein 70-2 (HSP70-2) expression in bladder urothelial carcinoma is associated with tumor progression and promotes migration and invasion
-
Garg, M., Kanojia, D., Seth, A., Kumar, R., Gupta, A., Surolia, A., and Suri, A. (2010) Heat shock protein 70-2 (HSP70-2) expression in bladder urothelial carcinoma is associated with tumor progression and promotes migration and invasion. Eur. J. Cancer 46, 207-215
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 207-215
-
-
Garg, M.1
Kanojia, D.2
Seth, A.3
Kumar, R.4
Gupta, A.5
Surolia, A.6
Suri, A.7
-
32
-
-
79953036864
-
Cell surface heat shock protein 90 modulates prostate cancer cell adhesion and invasion through the integrin-β1/focal adhesion kinase/c-Src signaling pathway
-
Liu, X., Yan, Z., Huang, L., Guo, M., Zhang, Z., and Guo, C. (2011) Cell surface heat shock protein 90 modulates prostate cancer cell adhesion and invasion through the integrin-β1/focal adhesion kinase/c-Src signaling pathway. Oncol. Rep. 25, 1343-1351
-
(2011)
Oncol. Rep.
, vol.25
, pp. 1343-1351
-
-
Liu, X.1
Yan, Z.2
Huang, L.3
Guo, M.4
Zhang, Z.5
Guo, C.6
-
33
-
-
2942716692
-
Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness
-
DOI 10.1038/ncb1131
-
Eustace, B. K., Sakurai, T., Stewart, J. K., Yimlamai, D., Unger, C., Zehetmeier, C., Lain, B., Torella, C., Henning, S. W., Beste, G., Scroggins, B. T., Neckers, L., Ilag, L. L., and Jay, D. G. (2004) Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness. Nat. Cell Biol. 6, 507-514 (Pubitemid 38786593)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.6
, pp. 507-514
-
-
Eustace, B.K.1
Sakurai, T.2
Stewart, J.K.3
Yimlamai, D.4
Unger, C.5
Zehetmeier, C.6
Lain, B.7
Torella, C.8
Henning, S.W.9
Beste, G.10
Scroggins, B.T.11
Neckers, L.12
Ilag, L.L.13
Jay, D.G.14
-
34
-
-
79954994442
-
Extracellular heat shock protein (Hsp)70 and Hsp90α assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion
-
Sims, J. D., McCready, J., and Jay, D. G. (2011) Extracellular heat shock protein (Hsp)70 and Hsp90α assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion. PLoS One 6, e18848
-
(2011)
PLoS One
, vol.6
-
-
Sims, J.D.1
McCready, J.2
Jay, D.G.3
-
35
-
-
79955478704
-
RNAi knockdown of Hop (Hsp70/Hsp90 organizing protein) decreases invasion via MMP-2 down-regulation
-
Walsh, N., Larkin, A., Swan, N., Conlon, K., Dowling, P., McDermott, R., and Clynes, M. (2011) RNAi knockdown of Hop (Hsp70/Hsp90 organizing protein) decreases invasion via MMP-2 down-regulation. Cancer Lett. 306, 180-189
-
(2011)
Cancer Lett.
, vol.306
, pp. 180-189
-
-
Walsh, N.1
Larkin, A.2
Swan, N.3
Conlon, K.4
Dowling, P.5
McDermott, R.6
Clynes, M.7
-
36
-
-
64949083563
-
Inhibition of cancer invasion and metastasis by targeting the molecular chaperone heat shock protein 90
-
Koga, F., Kihara, K., and Neckers, L. (2009) Inhibition of cancer invasion and metastasis by targeting the molecular chaperone heat shock protein 90. Anticancer Res. 29, 797-807
-
(2009)
Anticancer Res.
, vol.29
, pp. 797-807
-
-
Koga, F.1
Kihara, K.2
Neckers, L.3
-
37
-
-
12844251861
-
Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation
-
Leng, Y., Zhang, J., Badour, K., Arpaia, E., Freeman, S., Cheung, P., Siu, M., and Siminovitch, K. (2005) Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation. Proc. Natl. Acad. Sci. U.S.A. 102, 1098-10103
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 1098-10103
-
-
Leng, Y.1
Zhang, J.2
Badour, K.3
Arpaia, E.4
Freeman, S.5
Cheung, P.6
Siu, M.7
Siminovitch, K.8
-
38
-
-
77955477214
-
Secreted heat shock protein 90α induces colorectal cancer cell invasion through CD91/LRP-1 and NF-κB-mediated integrin αV expression
-
Chen, J. S., Hsu, Y. M., Chen, C. C., Chen, L. L., Lee, C. C., and Huang, T. S. (2010) Secreted heat shock protein 90α induces colorectal cancer cell invasion through CD91/LRP-1 and NF-κB-mediated integrin αV expression. J. Biol. Chem. 285, 25458-25466
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 25458-25466
-
-
Chen, J.S.1
Hsu, Y.M.2
Chen, C.C.3
Chen, L.L.4
Lee, C.C.5
Huang, T.S.6
|