Induction of early growth response-1 gene by interleukin-1β and tumor necrosis factor-α in normal human bone marrow stromal and osteoblastic cells: Regulation by a protein kinase C inhibitor

Molecular and Cellular Biochemistry

Volumn 156, Issue 1, 1996, Pages 69-77

  Chaudhary, Lala R ^a   Cheng, Su Li ^a   Avioli, Louis V ^a  

^a BARNES JEWISH HOSPITAL   (United States)

Author keywords

Egr 1; Human bone marrow stromal cells; Immediate early gene; Interleukin 1 ; Osteoblasts; Tumor necrosis factor

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; CYCLOHEXIMIDE; DACTINOMYCIN; IMMEDIATE EARLY PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN SYNTHESIS INHIBITOR; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; GENE CONTROL; GENE EXPRESSION REGULATION; GENE INDUCTION; HUMAN; HUMAN CELL; IMMEDIATE EARLY GENE; OSTEOBLAST; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; STROMA CELL;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; BASE SEQUENCE; BONE MARROW; BONE MARROW CELLS; CATTLE; CELLS, CULTURED; CONNECTIVE TISSUE; CULTURE MEDIA; CYCLOHEXIMIDE; DACTINOMYCIN; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; ENZYME INHIBITORS; FETAL BLOOD; GENE EXPRESSION REGULATION; GENES, IMMEDIATE-EARLY; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERLEUKIN-1; ISOQUINOLINES; MOLECULAR SEQUENCE DATA; OSTEOBLASTS; PIPERAZINES; PROTEIN KINASE C; PROTEIN SYNTHESIS INHIBITORS; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

BOVINAE;

EID: 0029878288     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Herschman HR; Primary response genes induced by growth factors and tumor promoters. Ann Rev Biochem 60: 281-319, 1991
2. Sukhatme VP, Cao X, Chang LC, Tsai-Morris C-H, Stamenkovich D, Ferreira PCP, Cohen DR, Edwards SA, Shows TB, Curran T, Le Beau MM, Adamson ED: A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization. Cell 53: 37-43, 1988
3. Cao X, Koski RA, Gashler A, McKiernan M, Morris CF, Gaffney R, Hay RV, Sukhatme VP: Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals. Mol Cell Biol 10: 1931-1939, 1990
4. McMahon AP, Champion JE, McMahon JA, Sukhatme VP: Develop-mental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues. Development 108: 281-287, 1990
5. Suva LJ, Ernst M, Rodan GA: Retinoic acid increases zif268 early gene expression in rat preosteoblastic cells. Mol Cell Biol 11: 2503-2510, 1991
6. Drummond IA, Madden SL, Rohwer-Nutter P, Bell GI, Sukhatme VP, Rauscher III FJ: Repression of the insulun-like growth factor n gene by the Wilms tumor suppressor WT1. Science 257: 674-678, 1992
7. Hyun SW, Park K, Lee YS, Lee YI, Kim S-J: Inhibition of protein phosphatases activates P4 promoter of the human insulin-like growth factor n gene through the specific promoter element J Biol Chem 269: 364-368, 1994
8. Tsai-Monis CH, Cao XM, Sukhatme VP: 5Flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene. Nucleic Acid Res 16: 8835-8846, 1988
9. Gashier AL, Bonthron DT, Madden SL, Rauscher m FJ, Collins T, Sukhatme VP: Human platelet derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1. Proc Natl Acad Sci USA 89: 10984-10988, 1992
10. Feng JQ, Harris MA, Ghosh-Choudhury N, Feng M, Mundy GR, Harris SE: Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes. Biochim Biophys Acta 1218: 221-224, 1994
11. Gowen M, Wood DD, Ihrie EJ, McGuire EB, Russell RGG: An interleukin 1 like factor stimulates bone resorption in vitro. Nature 306: 378-380, 1983
12. Thomson BM, Mundy GR, Chambers TJ: Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate osteoclastic bone resorption. J Immunol 138: 775-779, 1987
13. Pacifici R, Rifas L, Teitelbaum S, Slatopolsky E, McCracken R, Bergfeld M, Lee W, Avioli LV, Peck WA: Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis. Proc Natl Acad Sci USA 84: 4616-4620, 1987
14. Pfeilschifter J, Chenu C, Bird A, Mundy GR, Roodman GD: Interleukin 1 and tumor necrosis factor stimulate the formation of human osteoclast-like cells in vitro. J Bone Miner Res 4: 113-118, 1989
15. Pacifici R, Rifas L, McCracken R, Vered I, McMurray C, Avioli LV, Peck WA: Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release. Proc Natl Acad Sci USA 86: 2398-2402, 1989
16. Fujita T, Matsui T, Nakao Y, Shiozawa S, Imai Y: Cytokines and osteoporosis. Ann N Y Acad Sci 587: 371-375, 1990
17. Pacifici R, Carano A, Santoro SA, Rifas L, Jeffrey JJ, Malone JA, McCracken R, Avioli LV: Bone matrix constituents stimulate interleukin-1 release from human blood mononuclear cells. J Clin Invest 87: 221-228, 1991
18. Cao X, Guy GR, Sukhatme VP, Tan YH: Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts. J Biol Chem 267: 1345-1349, 1992
19. Owen M: Lineage of osteogenic cells and their relationship to the stromal system. In: W.A. Peck (ed.). Bone and Mineral Research. Excerpta Medica, Amsterdam, 1985 vol 3, pp. 1-25
20. Owen M, Friedenstein AJ: Stromal stem cells: marrow-derived osteogenic precursors. Ciba Found Symp 136: 42-60, 1988
21. Wlodarski KH: Properties and origin of osteoblasts. Clin Orthop Rel Res 252: 276-293, 1990
22. Nijweide PJ, Burger EH, Feyen JHM: Cells of Bone: proliferation, differentiation, and hormonal regulation. Physiol Rev 66: 855-886, 1986
23. Cheng S-L, Yang JW, Rifas L, Zhang S-F, Avioli LV: Differentiation of human bone marrow osteogenic stromal cells in vitro: Induction of the osteoblast phenotype by dexamethasone. Endocrinology 134: 277-286, 1994
24. Robey PG, Termine JD: Human bone cells in vitro. Calcif Tissue Int 37: 453-460, 1985
25. Rifas L, Halstead LR, Week WA, Avioli LV, Welgus HG: Human osteoblasts in vitro secrete tissue inhibitor of metalloproteinases and gelatinase but not interstitial collagenase as major cellular products. J Clin Invest 84: 248-254, 1989
26. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: a Laboratory Mannual, 2nd ed., Cold Spring Harbor Press, Cold Spring Harbor, NY, 1989