Peroxisome proliferator-activated receptor γ1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1β in articular chondrocytes

Arthritis Research and Therapy

Volumn 9, Issue , 2007, Pages

  Afif, Hassan ^a   Benderdour, Mohamed ^b   Mfuna Endam, Leandra ^a   Martel Pelletier, Johanne ^a   Pelletier, Jean Pierre ^a   Duval, Nicholas ^c   Fahmi, Hassan ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^c Centre de Convalescence   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLOOXYGENASE 2 INHIBITOR; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 17; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL CULTURE; CHONDROPATHY; CONTROLLED STUDY; DOWN REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INHIBITION KINETICS; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; PATHOGENESIS; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOTAL KNEE REPLACEMENT; BIOSYNTHESIS; CARTILAGE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; METABOLISM; OSTEOARTHRITIS; PHYSIOLOGY; WESTERN BLOTTING;

BLOTTING, WESTERN; CARTILAGE; CELLS, CULTURED; CHONDROCYTES; DINOPROSTONE; DOWN-REGULATION; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-17; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; OSTEOARTHRITIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PPAR GAMMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34247196696     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2151     Document Type: Article

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