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Volumn 85, Issue 5, 2011, Pages 235-243

New insights into the role of PPARs

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST;

EID: 80053583204     PISSN: 09523278     EISSN: 15322823     Source Type: Journal    
DOI: 10.1016/j.plefa.2011.04.016     Document Type: Article
Times cited : (51)

References (69)
  • 1
    • 33645863768 scopus 로고    scopus 로고
    • Transcriptional regulation of metabolism
    • Desvergne B., Michalik L., Wahli W. Transcriptional regulation of metabolism. Physiol. Rev. 2006, 86:465-514.
    • (2006) Physiol. Rev. , vol.86 , pp. 465-514
    • Desvergne, B.1    Michalik, L.2    Wahli, W.3
  • 2
    • 33751533892 scopus 로고    scopus 로고
    • International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors
    • Michalik L., Auwerx J., Berger J.P., et al. International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacol. Rev. 2006, 58:726-741.
    • (2006) Pharmacol. Rev. , vol.58 , pp. 726-741
    • Michalik, L.1    Auwerx, J.2    Berger, J.P.3
  • 3
    • 0026517010 scopus 로고
    • Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors
    • Dreyer C., Krey G., Keller H., Givel F., Helftenbein G., Wahli W. Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors. Cell 1992, 68:879-887.
    • (1992) Cell , vol.68 , pp. 879-887
    • Dreyer, C.1    Krey, G.2    Keller, H.3    Givel, F.4    Helftenbein, G.5    Wahli, W.6
  • 4
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I., Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990, 347:645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 5
    • 0033574663 scopus 로고    scopus 로고
    • A unified nomenclature system for the nuclear receptor superfamily
    • Laudet V., Auwerx J., Gustafsson J.A., Wahli W. A unified nomenclature system for the nuclear receptor superfamily. Cell 1999, 97:161-163.
    • (1999) Cell , vol.97 , pp. 161-163
    • Laudet, V.1    Auwerx, J.2    Gustafsson, J.A.3    Wahli, W.4
  • 6
    • 32644460092 scopus 로고    scopus 로고
    • From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
    • Feige J.N., Gelman L., Michalik L., Desvergne B., Wahli W. From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog. Lipid Res. 2006, 45:120-159.
    • (2006) Prog. Lipid Res. , vol.45 , pp. 120-159
    • Feige, J.N.1    Gelman, L.2    Michalik, L.3    Desvergne, B.4    Wahli, W.5
  • 7
    • 12144291563 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse
    • Imai T., Takakuwa R., Marchand S., et al. Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc. Natl. Acad. Sci. USA 2004, 101:4543-4547.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 4543-4547
    • Imai, T.1    Takakuwa, R.2    Marchand, S.3
  • 9
    • 0036245242 scopus 로고    scopus 로고
    • Getting under the skin of epidermal morphogenesis
    • Fuchs E., Raghavan S. Getting under the skin of epidermal morphogenesis. Nat. Rev. Genet. 2002, 3:199-209.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 199-209
    • Fuchs, E.1    Raghavan, S.2
  • 11
    • 42949178186 scopus 로고    scopus 로고
    • Thematic review series: skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology
    • Schmuth M., Jiang Y.J., Dubrac S., Elias P.M., Feingold K.R. Thematic review series: skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology. J. Lipid Res. 2008, 49:499-509.
    • (2008) J. Lipid Res. , vol.49 , pp. 499-509
    • Schmuth, M.1    Jiang, Y.J.2    Dubrac, S.3    Elias, P.M.4    Feingold, K.R.5
  • 12
    • 34547602370 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) in skin health, repair and disease
    • Michalik L., Wahli W. Peroxisome proliferator-activated receptors (PPARs) in skin health, repair and disease. Biochim. Biophys. Acta 2007, 1771:991-998.
    • (2007) Biochim. Biophys. Acta , vol.1771 , pp. 991-998
    • Michalik, L.1    Wahli, W.2
  • 13
    • 0035921419 scopus 로고    scopus 로고
    • Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice
    • Michalik L., Desvergne B., Tan N.S., et al. Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J. Cell Biol. 2001, 154:799-814.
    • (2001) J. Cell Biol. , vol.154 , pp. 799-814
    • Michalik, L.1    Desvergne, B.2    Tan, N.S.3
  • 14
    • 0035893364 scopus 로고    scopus 로고
    • Critical roles of PPAR beta/delta in keratinocyte response to inflammation
    • Tan N.S., Michalik L., Noy N., et al. Critical roles of PPAR beta/delta in keratinocyte response to inflammation. Genes Dev. 2001, 15:3263-3277.
    • (2001) Genes Dev. , vol.15 , pp. 3263-3277
    • Tan, N.S.1    Michalik, L.2    Noy, N.3
  • 15
    • 9144251051 scopus 로고    scopus 로고
    • Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression
    • Tan N.S., Michalik L., Di-Poi N., et al. Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression. EMBO J. 2004, 23:4211-4221.
    • (2004) EMBO J. , vol.23 , pp. 4211-4221
    • Tan, N.S.1    Michalik, L.2    Di-Poi, N.3
  • 16
    • 14044265696 scopus 로고    scopus 로고
    • Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development
    • Di-Poi N., Ng C.Y., Tan N.S., et al. Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development. Mol. Cell Biol. 2005, 25:1696-1712.
    • (2005) Mol. Cell Biol. , vol.25 , pp. 1696-1712
    • Di-Poi, N.1    Ng, C.Y.2    Tan, N.S.3
  • 17
    • 24044477561 scopus 로고    scopus 로고
    • Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics
    • Tan N.S., Michalik L., Desvergne B., Wahli W. Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics. J. Biol. Chem. 2005, 280:18163-18170.
    • (2005) J. Biol. Chem. , vol.280 , pp. 18163-18170
    • Tan, N.S.1    Michalik, L.2    Desvergne, B.3    Wahli, W.4
  • 18
    • 64049095625 scopus 로고    scopus 로고
    • Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing
    • Chong H.C., Tan M.J., Philippe V., et al. Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing. J. Cell Biol. 2009, 184:817-831.
    • (2009) J. Cell Biol. , vol.184 , pp. 817-831
    • Chong, H.C.1    Tan, M.J.2    Philippe, V.3
  • 19
    • 0037150728 scopus 로고    scopus 로고
    • Src in cancer: deregulation and consequences for cell behaviour
    • Frame M.C. Src in cancer: deregulation and consequences for cell behaviour. Biochim. Biophys. Acta 2002, 1602:114-130.
    • (2002) Biochim. Biophys. Acta , vol.1602 , pp. 114-130
    • Frame, M.C.1
  • 20
    • 60149087110 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12)-enhanced angiogenesis of human basal cell carcinoma cells involves ERK1/2-NF-kappaB/interleukin-6 pathway
    • Chu C.Y., Cha S.T., Lin W.C., et al. Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12)-enhanced angiogenesis of human basal cell carcinoma cells involves ERK1/2-NF-kappaB/interleukin-6 pathway. Carcinogenesis 2009, 30:205-213.
    • (2009) Carcinogenesis , vol.30 , pp. 205-213
    • Chu, C.Y.1    Cha, S.T.2    Lin, W.C.3
  • 21
    • 77954838442 scopus 로고    scopus 로고
    • Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations
    • C. Hafner, M. Landthaler and T. Vogt, Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations, Exp. Dermatol. (2010).
    • (2010) Exp. Dermatol.
    • Hafner, C.1    Landthaler, M.2    Vogt, T.3
  • 22
    • 0032448111 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptor subtypes during the differentiation of human keratinocytes
    • Rivier M., Safonova I., Lebrun P., Griffiths C.E., Ailhaud G., Michel S. Differential expression of peroxisome proliferator-activated receptor subtypes during the differentiation of human keratinocytes. J. Invest. Dermatol. 1998, 111:1116-1121.
    • (1998) J. Invest. Dermatol. , vol.111 , pp. 1116-1121
    • Rivier, M.1    Safonova, I.2    Lebrun, P.3    Griffiths, C.E.4    Ailhaud, G.5    Michel, S.6
  • 23
    • 10744228768 scopus 로고    scopus 로고
    • Expression and localization of peroxisome proliferator-activated receptors and nuclear factor kappaB in normal and lesional psoriatic skin
    • Westergaard M., Henningsen J., Johansen C., et al. Expression and localization of peroxisome proliferator-activated receptors and nuclear factor kappaB in normal and lesional psoriatic skin. J. Invest. Dermatol. 2003, 121:1104-1117.
    • (2003) J. Invest. Dermatol. , vol.121 , pp. 1104-1117
    • Westergaard, M.1    Henningsen, J.2    Johansen, C.3
  • 26
    • 17444371632 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in squamous cell carcinoma and its precursors
    • Nijsten T., Geluyckens E., Colpaert C., Lambert J. Peroxisome proliferator-activated receptors in squamous cell carcinoma and its precursors. J. Cutaneous Pathol. 2005, 32:340-347.
    • (2005) J. Cutaneous Pathol. , vol.32 , pp. 340-347
    • Nijsten, T.1    Geluyckens, E.2    Colpaert, C.3    Lambert, J.4
  • 27
    • 47349100516 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and the human skin: importance of PPARs in skin physiology and dermatologic diseases
    • Sertznig P., Seifert M., Tilgen W., Reichrath J. Peroxisome proliferator-activated receptors (PPARs) and the human skin: importance of PPARs in skin physiology and dermatologic diseases. Am. J. Clin. Dermatol. 2008, 9:15-31.
    • (2008) Am. J. Clin. Dermatol. , vol.9 , pp. 15-31
    • Sertznig, P.1    Seifert, M.2    Tilgen, W.3    Reichrath, J.4
  • 28
    • 76749137586 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) acts as regulator of metabolism linked to multiple cellular functions
    • Wagner K.D., Wagner N. Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) acts as regulator of metabolism linked to multiple cellular functions. Pharmacol. Ther. 2010, 125:423-435.
    • (2010) Pharmacol. Ther. , vol.125 , pp. 423-435
    • Wagner, K.D.1    Wagner, N.2
  • 29
    • 58149466606 scopus 로고    scopus 로고
    • PPARs mediate lipid signaling in inflammation and cancer
    • Michalik L., Wahli W. PPARs mediate lipid signaling in inflammation and cancer. PPAR Res. 2008, 2008:134059.
    • (2008) PPAR Res. , vol.2008 , pp. 134059
    • Michalik, L.1    Wahli, W.2
  • 30
    • 70349177505 scopus 로고    scopus 로고
    • Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in cell proliferation and cancer
    • J.M. Peters and F.J. Gonzalez, Sorting out the functional role(s) of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in cell proliferation and cancer, Biochim. Biophys. Acta 1796 (2009) 230-241.
    • (2009) Biochim. Biophys. Acta. , vol.1796 , pp. 230-241
    • Peters, J.M.1    Gonzalez, F.J.2
  • 31
    • 0034666157 scopus 로고    scopus 로고
    • Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene
    • Kersten S., Mandard S., Tan N.S., et al. Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J. Biol. Chem. 2000, 275:28488-28493.
    • (2000) J. Biol. Chem. , vol.275 , pp. 28488-28493
    • Kersten, S.1    Mandard, S.2    Tan, N.S.3
  • 32
    • 63049083171 scopus 로고    scopus 로고
    • Twist-1 is a PPARdelta-inducible, negative-feedback regulator of PGC-1alpha in brown fat metabolism
    • Pan D., Fujimoto M., Lopes A., Wang Y.X. Twist-1 is a PPARdelta-inducible, negative-feedback regulator of PGC-1alpha in brown fat metabolism. Cell 2009, 137:73-86.
    • (2009) Cell , vol.137 , pp. 73-86
    • Pan, D.1    Fujimoto, M.2    Lopes, A.3    Wang, Y.X.4
  • 33
    • 41149134486 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 is a molecular target for the peroxisome proliferator-activated receptor delta
    • Kim H.J., Ham S.A., Kim S.U., et al. Transforming growth factor-beta1 is a molecular target for the peroxisome proliferator-activated receptor delta. Circ. Res. 2008, 102:193-200.
    • (2008) Circ. Res. , vol.102 , pp. 193-200
    • Kim, H.J.1    Ham, S.A.2    Kim, S.U.3
  • 34
    • 34249087361 scopus 로고    scopus 로고
    • Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors
    • Schug T.T., Berry D.C., Shaw N.S., Travis S.N., Noy N. Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. Cell 2007, 129:723-733.
    • (2007) Cell , vol.129 , pp. 723-733
    • Schug, T.T.1    Berry, D.C.2    Shaw, N.S.3    Travis, S.N.4    Noy, N.5
  • 35
    • 77953508709 scopus 로고    scopus 로고
    • Fatty acid-binding protein 5 and PPARbeta/delta are critical mediators of epidermal growth factor receptor-induced carcinoma cell growth
    • Kannan-Thulasiraman P., Seachrist D.D., Mahabeleshwar G.H., Jain M.K., Noy N. Fatty acid-binding protein 5 and PPARbeta/delta are critical mediators of epidermal growth factor receptor-induced carcinoma cell growth. J. Biol. Chem. 2010, 285:19106-19115.
    • (2010) J. Biol. Chem. , vol.285 , pp. 19106-19115
    • Kannan-Thulasiraman, P.1    Seachrist, D.D.2    Mahabeleshwar, G.H.3    Jain, M.K.4    Noy, N.5
  • 36
    • 0034052579 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis
    • Peters J.M., Rusyn I., Rose M.L., Gonzalez F.J., Thurman R.G. Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis. Carcinogenesis 2000, 21:823-826.
    • (2000) Carcinogenesis , vol.21 , pp. 823-826
    • Peters, J.M.1    Rusyn, I.2    Rose, M.L.3    Gonzalez, F.J.4    Thurman, R.G.5
  • 37
    • 0037221210 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells
    • Hellemans K., Michalik L., Dittie A., et al. Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells. Gastroenterology 2003, 124:184-201.
    • (2003) Gastroenterology , vol.124 , pp. 184-201
    • Hellemans, K.1    Michalik, L.2    Dittie, A.3
  • 38
    • 32644443742 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression
    • Patsouris D., Reddy J.K., Muller M., Kersten S. Peroxisome proliferator-activated receptor alpha mediates the effects of high-fat diet on hepatic gene expression. Endocrinology 2006, 147:1508-1516.
    • (2006) Endocrinology , vol.147 , pp. 1508-1516
    • Patsouris, D.1    Reddy, J.K.2    Muller, M.3    Kersten, S.4
  • 39
    • 0027278522 scopus 로고
    • Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR)
    • Dreyer C., Keller H., Mahfoudi A., Laudet V., Krey G., Wahli W. Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR). Biol. Cell 1993, 77:67-76.
    • (1993) Biol. Cell , vol.77 , pp. 67-76
    • Dreyer, C.1    Keller, H.2    Mahfoudi, A.3    Laudet, V.4    Krey, G.5    Wahli, W.6
  • 40
    • 0032699670 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
    • Kersten S., Seydoux J., Peters J.M., Gonzalez F.J., Desvergne B., Wahli W. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J. Clin. Invest. 1999, 103:1489-1498.
    • (1999) J. Clin. Invest. , vol.103 , pp. 1489-1498
    • Kersten, S.1    Seydoux, J.2    Peters, J.M.3    Gonzalez, F.J.4    Desvergne, B.5    Wahli, W.6
  • 41
    • 0034842626 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor alpha regulates amino acid metabolism
    • Kersten S., Mandard S., Escher P., et al. The peroxisome proliferator-activated receptor alpha regulates amino acid metabolism. FASEB J 2001, 15:1971-1978.
    • (2001) FASEB J , vol.15 , pp. 1971-1978
    • Kersten, S.1    Mandard, S.2    Escher, P.3
  • 42
    • 80053610681 scopus 로고    scopus 로고
    • PPARalpha, a key regulator of hepatic energy homeostasis in health and disease
    • Springer, Berlin Heidelberg, J.-F. Dufour, P.-A. Clavien (Eds.)
    • Leuenberger N., Wahli W. PPARalpha, a key regulator of hepatic energy homeostasis in health and disease. Signaling Pathways in Liver Diseases 2010, 305-315. Springer, Berlin Heidelberg. J.-F. Dufour, P.-A. Clavien (Eds.).
    • (2010) Signaling Pathways in Liver Diseases , pp. 305-315
    • Leuenberger, N.1    Wahli, W.2
  • 43
    • 0030060358 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm
    • T. Lemberger, R. Saladin, M. Vazquez, et al., Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm, J. Biol. Chem. 271 (1996) 1764-1769.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1764-1769
    • Lemberger, T.1    Saladin, R.2    Vazquez, M.3
  • 44
    • 33747157406 scopus 로고    scopus 로고
    • Nuclear receptor expression links the circadian clock to metabolism
    • Yang X., Downes M., Yu R.T., et al. Nuclear receptor expression links the circadian clock to metabolism. Cell 2006, 126:801-810.
    • (2006) Cell , vol.126 , pp. 801-810
    • Yang, X.1    Downes, M.2    Yu, R.T.3
  • 45
    • 77951297855 scopus 로고    scopus 로고
    • Altered circadian rhythm of the clock genes in fibrotic livers induced by carbon tetrachloride
    • Chen P., Kakan X., Zhang J. Altered circadian rhythm of the clock genes in fibrotic livers induced by carbon tetrachloride. FEBS Lett. 2010, 584:1597-1601.
    • (2010) FEBS Lett. , vol.584 , pp. 1597-1601
    • Chen, P.1    Kakan, X.2    Zhang, J.3
  • 46
    • 33745329809 scopus 로고    scopus 로고
    • The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification
    • Gachon F., Olela F.F., Schaad O., Descombes P., Schibler U. The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab. 2006, 4:25-36.
    • (2006) Cell Metab. , vol.4 , pp. 25-36
    • Gachon, F.1    Olela, F.F.2    Schaad, O.3    Descombes, P.4    Schibler, U.5
  • 47
    • 69049113889 scopus 로고    scopus 로고
    • Fatty acid synthesis and PPARalpha hand in hand
    • Rotman N., Wahli W. Fatty acid synthesis and PPARalpha hand in hand. Chem. Biol. 2009, 16:801-802.
    • (2009) Chem. Biol. , vol.16 , pp. 801-802
    • Rotman, N.1    Wahli, W.2
  • 48
    • 68149098866 scopus 로고    scopus 로고
    • Identification of a physiologically relevant endogenous ligand for PPARalpha in liver
    • Chakravarthy M.V., Lodhi I.J., Yin L., et al. Identification of a physiologically relevant endogenous ligand for PPARalpha in liver. Cell 2009, 138:476-488.
    • (2009) Cell , vol.138 , pp. 476-488
    • Chakravarthy, M.V.1    Lodhi, I.J.2    Yin, L.3
  • 50
    • 76749139528 scopus 로고    scopus 로고
    • The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors
    • Schmutz I., Ripperger J.A., Baeriswyl-Aebischer S., Albrecht U. The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors. Genes Dev. 2010, 24:345-357.
    • (2010) Genes Dev. , vol.24 , pp. 345-357
    • Schmutz, I.1    Ripperger, J.A.2    Baeriswyl-Aebischer, S.3    Albrecht, U.4
  • 51
    • 33746591126 scopus 로고    scopus 로고
    • Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock
    • Canaple L., Rambaud J., Dkhissi-Benyahya O., et al. Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock. Mol. Endocrinol. 2006, 20:1715-1727.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 1715-1727
    • Canaple, L.1    Rambaud, J.2    Dkhissi-Benyahya, O.3
  • 52
    • 33744497029 scopus 로고    scopus 로고
    • Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis
    • Clodfelter K.H., Holloway M.G., Hodor P., Park S.H., Ray W.J., Waxman D.J. Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis. Mol. Endocrinol. 2006, 20:1333-1351.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 1333-1351
    • Clodfelter, K.H.1    Holloway, M.G.2    Hodor, P.3    Park, S.H.4    Ray, W.J.5    Waxman, D.J.6
  • 53
    • 34249795488 scopus 로고    scopus 로고
    • Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus
    • Holloway M.G., Cui Y., Laz E.V., Hosui A., Hennighausen L., Waxman D.J. Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus. Endocrinology 2007, 148:1977-1986.
    • (2007) Endocrinology , vol.148 , pp. 1977-1986
    • Holloway, M.G.1    Cui, Y.2    Laz, E.V.3    Hosui, A.4    Hennighausen, L.5    Waxman, D.J.6
  • 54
    • 0029117138 scopus 로고
    • A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP
    • Yokomori N., Kobayashi R., Moore R., Sueyoshi T., Negishi M. A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP. Mol. Cell Biol. 1995, 15:5355-5362.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 5355-5362
    • Yokomori, N.1    Kobayashi, R.2    Moore, R.3    Sueyoshi, T.4    Negishi, M.5
  • 55
    • 0032491614 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis
    • Costet P., Legendre C., More J., Edgar A., Galtier P., Pineau T. Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis. J. Biol. Chem. 1998, 273:29577-29585.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29577-29585
    • Costet, P.1    Legendre, C.2    More, J.3    Edgar, A.4    Galtier, P.5    Pineau, T.6
  • 56
    • 0032530765 scopus 로고    scopus 로고
    • A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice
    • Djouadi F., Weinheimer C.J., Saffitz J.E., et al. A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice. J. Clin. Invest. 1998, 102:1083-1091.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1083-1091
    • Djouadi, F.1    Weinheimer, C.J.2    Saffitz, J.E.3
  • 57
    • 0037225347 scopus 로고    scopus 로고
    • Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: influence of pituitary and gonadal hormones
    • Jalouli M., Carlsson L., Ameen C., et al. Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: influence of pituitary and gonadal hormones. Endocrinology 2003, 144:101-109.
    • (2003) Endocrinology , vol.144 , pp. 101-109
    • Jalouli, M.1    Carlsson, L.2    Ameen, C.3
  • 58
    • 0021248040 scopus 로고
    • Quantitative microscopy comparison of peroxisome proliferation by the lipid-regulating agent gemfibrozil in several species
    • Gray R.H., de la Iglesia F.A. Quantitative microscopy comparison of peroxisome proliferation by the lipid-regulating agent gemfibrozil in several species. Hepatology 1984, 4:520-530.
    • (1984) Hepatology , vol.4 , pp. 520-530
    • Gray, R.H.1    de la Iglesia, F.A.2
  • 59
    • 33846616376 scopus 로고    scopus 로고
    • A novel peroxisome proliferator-activated receptor responsive element-luciferase reporter mouse reveals gender specificity of peroxisome proliferator-activated receptor activity in liver
    • Ciana P., Biserni A., Tatangelo L., et al. A novel peroxisome proliferator-activated receptor responsive element-luciferase reporter mouse reveals gender specificity of peroxisome proliferator-activated receptor activity in liver. Mol. Endocrinol. 2007, 21:388-400.
    • (2007) Mol. Endocrinol. , vol.21 , pp. 388-400
    • Ciana, P.1    Biserni, A.2    Tatangelo, L.3
  • 60
    • 70349659645 scopus 로고    scopus 로고
    • Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice
    • Leuenberger N., Pradervand S., Wahli W. Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice. J. Clin. Invest. 2009, 119:3138-3148.
    • (2009) J. Clin. Invest. , vol.119 , pp. 3138-3148
    • Leuenberger, N.1    Pradervand, S.2    Wahli, W.3
  • 61
    • 77949878458 scopus 로고    scopus 로고
    • SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR
    • Pourcet B., Pineda-Torra I., Derudas B., Staels B., Glineur C. SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR. J. Biol. Chem. 2010, 285:5983-5992.
    • (2010) J. Biol. Chem. , vol.285 , pp. 5983-5992
    • Pourcet, B.1    Pineda-Torra, I.2    Derudas, B.3    Staels, B.4    Glineur, C.5
  • 62
    • 33746013253 scopus 로고    scopus 로고
    • Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues
    • Tang W., Eggertsen G., Chiang J.Y., Norlin M. Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues. J. Steroid Biochem. Mol. Biol. 2006, 100:42-51.
    • (2006) J. Steroid Biochem. Mol. Biol. , vol.100 , pp. 42-51
    • Tang, W.1    Eggertsen, G.2    Chiang, J.Y.3    Norlin, M.4
  • 63
    • 41549096838 scopus 로고    scopus 로고
    • CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol-potential role(s) for estrogen signaling
    • Pettersson H., Holmberg L., Axelson M., Norlin M. CYP7B1-mediated metabolism of dehydroepiandrosterone and 5alpha-androstane-3beta,17beta-diol-potential role(s) for estrogen signaling. FEBS J. 2008, 275:1778-1789.
    • (2008) FEBS J. , vol.275 , pp. 1778-1789
    • Pettersson, H.1    Holmberg, L.2    Axelson, M.3    Norlin, M.4
  • 64
    • 0035870101 scopus 로고    scopus 로고
    • Cyp7b1 catalyses the 7alpha-hydroxylation of dehydroepiandrosterone and 25-hydroxycholesterol in rat prostate
    • Martin C., Bean R., Rose K., Habib F., Seckl J. cyp7b1 catalyses the 7alpha-hydroxylation of dehydroepiandrosterone and 25-hydroxycholesterol in rat prostate. Biochem. J. 2001, 355:509-515.
    • (2001) Biochem. J. , vol.355 , pp. 509-515
    • Martin, C.1    Bean, R.2    Rose, K.3    Habib, F.4    Seckl, J.5
  • 65
    • 34948820661 scopus 로고    scopus 로고
    • 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen
    • Umetani M., Domoto H., Gormley A.K., et al. 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. Nat. Med. 2007, 13:1185-1192.
    • (2007) Nat. Med. , vol.13 , pp. 1185-1192
    • Umetani, M.1    Domoto, H.2    Gormley, A.K.3
  • 66
    • 33745187361 scopus 로고    scopus 로고
    • Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity
    • Yamamoto Y., Moore R., Hess H.A., et al. Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity. J. Biol. Chem. 2006, 281:16625-16631.
    • (2006) J. Biol. Chem. , vol.281 , pp. 16625-16631
    • Yamamoto, Y.1    Moore, R.2    Hess, H.A.3
  • 67
    • 34250378599 scopus 로고    scopus 로고
    • Intrahepatic cholestasis of pregnancy
    • Pusl T., Beuers U. Intrahepatic cholestasis of pregnancy. Orphanet J. Rare Dis. 2007, 2:26.
    • (2007) Orphanet J. Rare Dis. , vol.2 , pp. 26
    • Pusl, T.1    Beuers, U.2
  • 68
    • 0029067225 scopus 로고
    • Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements
    • Keller H., Givel F., Perroud M., Wahli W. Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements. Mol. Endocrinol. 1995, 9:794-804.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 794-804
    • Keller, H.1    Givel, F.2    Perroud, M.3    Wahli, W.4
  • 69
    • 1642505593 scopus 로고    scopus 로고
    • Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse
    • Hewitt K.N., Pratis K., Jones M.E., Simpson E.R. Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse. Endocrinology 2004, 145:1842-1848.
    • (2004) Endocrinology , vol.145 , pp. 1842-1848
    • Hewitt, K.N.1    Pratis, K.2    Jones, M.E.3    Simpson, E.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.