Peroxisome proliferator-activated receptor gamma activators inhibit MMP-1 production in human synovial fibroblasts likely by reducing the binding of the activator protein 1

Osteoarthritis and Cartilage

Volumn 10, Issue 2, 2002, Pages 100-108

  Fahmi, H ^a   Pelletier, J P ^a   Di Battista, J A ^a   Cheung, H S ^b   Fernandes, J C ^a   Martel Pelletier, J ^a  

^a NOTRE DAME HOSPITAL   (Canada)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

AP 1; MMP 1; PPAR ; Synovial fibroblasts

Indexed keywords

INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN J2; ROSIGLITAZONE; TRANSCRIPTION FACTOR AP 1;

AGED; ARTICLE; ASSAY; BINDING AFFINITY; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTROPHORETIC MOBILITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SYNTHESIS; FIBROBLAST; GENE ACTIVATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; JOINT DESTRUCTION; MOLECULAR DYNAMICS; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNOVIUM;

EID: 0036151348     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1053/joca.2001.0485     Document Type: Article

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