-
1
-
-
0026646604
-
Amyloid β -peptide is produced by cultured cells during normal metabolism
-
Haass, C., Schlossmacher, M. G., Hung, A. Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B. L., Lieberburg, I., Koo, E. H., Schenk, D., Teplow, D. B., and Selkoe, D. J. (1992) Amyloid β -peptide is produced by cultured cells during normal metabolism Nature 359, 322-325
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostaszewski, B.L.6
Lieberburg, I.7
Koo, E.H.8
Schenk, D.9
Teplow, D.B.10
Selkoe, D.J.11
-
2
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's β -peptide from biological fluids
-
Seubert, P., Vigo-Pelfrey, C., Esch, F., Lee, M., Dovey, H., Davis, D., Sinha, S., Schlossmacher, M., Whaley, J., Swindlehurst, C., McCormack, R., Wolfert, R., Selkoe, D., Lieberburg, I., and Schenk, D. (1992) Isolation and quantification of soluble Alzheimer's β -peptide from biological fluids Nature 359, 325-327
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
Sinha, S.7
Schlossmacher, M.8
Whaley, J.9
Swindlehurst, C.10
McCormack, R.11
Wolfert, R.12
Selkoe, D.13
Lieberburg, I.14
Schenk, D.15
-
3
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
Hardy, J. and Selkoe, D. J. (2002) The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics Science 297, 353-356 (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
4
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
DOI 10.1038/nrn1007
-
Soto, C. (2003) Unfolding the role of protein misfolding in neurodegenerative diseases Nat. Rev. Neurosci. 4, 49-60 (Pubitemid 37271088)
-
(2003)
Nature Reviews Neuroscience
, vol.4
, Issue.1
, pp. 49-60
-
-
Soto, C.1
-
5
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
DOI 10.1146/annurev.biochem.75.101304.123901
-
Chiti, F. and Dobson, C. M. (2006) Protein Misfolding, Functional Amyloid, and Human Disease Annu. Rev. Biochem. 75, 333-366 (Pubitemid 44118036)
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
6
-
-
70349923038
-
Alzheimer's Disease: From Pathology to Therapeutic Approaches
-
Jakob-Roetne, R. and Jacobsen, H. (2009) Alzheimer's Disease: From Pathology to Therapeutic Approaches Angew. Chem., Int. Ed. 48, 3030-3059
-
(2009)
Angew. Chem., Int. Ed.
, vol.48
, pp. 3030-3059
-
-
Jakob-Roetne, R.1
Jacobsen, H.2
-
7
-
-
63849197629
-
Amyloid β-Protein Assembly and Alzheimer Disease
-
Roychaudhuri, R., Yang, M., Hoshi, M. M., and Teplow, D. B. (2009) Amyloid β-Protein Assembly and Alzheimer Disease J. Biol. Chem. 284 (8) 4749-4753
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.8
, pp. 4749-4753
-
-
Roychaudhuri, R.1
Yang, M.2
Hoshi, M.M.3
Teplow, D.B.4
-
8
-
-
0037041426
-
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
-
DOI 10.1038/416535a
-
Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Naturally secreted oligomers of amyloid-β protein potently inhibit hippocampal long-term potentiation in vivo Nature 416, 535-539 (Pubitemid 34288854)
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
9
-
-
34248190279
-
Aβ Oligomers π - π a decade of discovery
-
Walsh, D. M. and Selkoe, D. J. (2007) Aβ Oligomers π - π a decade of discovery J. Neurochem. 101, 1172-1184
-
(2007)
J. Neurochem.
, vol.101
, pp. 1172-1184
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
10
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
DOI 10.1038/416507a
-
Bucciantini, M., Giannoni, E., Chiti, F., Baroni, F., Formigli, L., Zurdo, J., Taddei, N., Ramponi, G., Dobson, C. M., and Stefani, M. (2002) Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases Nature 416, 507-511 (Pubitemid 34288846)
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
11
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
DOI 10.1126/science.1079469
-
Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis Science 300, 486-489 (Pubitemid 36444329)
-
(2003)
Science
, vol.300
, Issue.5618
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabel, C.G.7
-
12
-
-
77951975748
-
Structural conversion of neurotoxic amyloid-β(1-42) oligomers to fibrils
-
Ahmed, M., Davis, J., Aucoin, D., Sato, T., Ahuja, S., Aimoto, S., Elliott, J. I., Sostrand, W. E. V., and Smith, S. O. (2010) Structural conversion of neurotoxic amyloid-β(1-42) oligomers to fibrils Nat. Struct. Mol. Biol. 17, 561-567
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 561-567
-
-
Ahmed, M.1
Davis, J.2
Aucoin, D.3
Sato, T.4
Ahuja, S.5
Aimoto, S.6
Elliott, J.I.7
Sostrand, W.E.V.8
Smith, S.O.9
-
13
-
-
0035997080
-
Supramolecular structure in full-length Alzheimer's β-amyloid fibrils: Evidence for a parallel β-sheet organization from solid-state nuclear magnetic resonance
-
Balbach, J. J., Petkova, A. T., Oyler, N. A., Antzutkin, O. N., Gordon, D. J., Meredith, S. C., and Tycko, R. (2002) Supramolecular Structure in Full-Length Alzheimer's β-Amyloid Fibrils: Evidence for a Parallel β-Sheet Organization from Solid-State Nuclear Magnetic Resonance Biophys. J. 83, 1205-1216 (Pubitemid 34803651)
-
(2002)
Biophysical Journal
, vol.83
, Issue.2
, pp. 1205-1216
-
-
Balbach, J.J.1
Petkova, A.T.2
Oyler, N.A.3
Antzutkin, O.N.4
Gordon, D.J.5
Meredith, S.C.6
Tycko, R.7
-
14
-
-
0037168655
-
A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR
-
DOI 10.1073/pnas.262663499
-
Petkova, A. T., Ishii, Y., Balbach, J. J., Antzutkin, O. N., Leapman, R. D., Delaglio, F., and Tycko, R. (2002) A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR Proc. Natl. Acad. Sci. U.S.A. 99, 16742-16747 (Pubitemid 36034043)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.26
, pp. 16742-16747
-
-
Petkova, A.T.1
Ishii, Y.2
Balbach, J.J.3
Antzutkin, O.N.4
Leapman, R.D.5
Delaglio, F.6
Tycko, R.7
-
15
-
-
12244249201
-
Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils
-
DOI 10.1126/science.1105850
-
Petkova, A. T., Leapman, R. D., Guo, Z., Yau, W.-M., Mattson, M. P., and Tycko, R. (2005) Self-Propagating, Molecular-Level Polymorphism in Alzheimer's β-Amyloid Fibrils Science 307, 262-265 (Pubitemid 40116242)
-
(2005)
Science
, vol.307
, Issue.5707
, pp. 262-265
-
-
Petkova, A.T.1
Leapman, R.D.2
Guo, Z.3
Yau, W.-M.4
Mattson, M.P.5
Tycko, R.6
-
16
-
-
30744433878
-
Experimental constraints on quaternary structure in Alzheimer's β-amyloid fibrils
-
DOI 10.1021/bi051952q
-
Petkova, A. T., Yau, W.-M., and Tycko, R. (2006) Experimental Constraints on Quaternary Structure in Alzheimer's β-Amyloid Fibrils Biochemistry 45, 498-512 (Pubitemid 43100415)
-
(2006)
Biochemistry
, vol.45
, Issue.2
, pp. 498-512
-
-
Petkova, A.T.1
Yau, W.-M.2
Tycko, R.3
-
17
-
-
57449091884
-
Molecular structural basis for polymorphism in Alzheimer's β-amyloid fibrils
-
Paravastu, A. K., Leapman, R. D., Yau, W.-M., and Tycko, R. (2008) Molecular structural basis for polymorphism in Alzheimer's β-amyloid fibrils Proc. Natl. Acad. Sci. U.S.A. 105, 18349-18354
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 18349-18354
-
-
Paravastu, A.K.1
Leapman, R.D.2
Yau, W.-M.3
Tycko, R.4
-
18
-
-
79953765150
-
Solid-State NMR Studies of Amyloid Fibril Structure
-
Tycko, R. (2011) Solid-State NMR Studies of Amyloid Fibril Structure Annu. Rev. Phys. Chem. 62, 279-299
-
(2011)
Annu. Rev. Phys. Chem.
, vol.62
, pp. 279-299
-
-
Tycko, R.1
-
19
-
-
17844410343
-
Folding events in the 21-30 region of amyloid β-protein (Aβ) studied in silico
-
DOI 10.1073/pnas.0502006102
-
Borreguero, J. M., Urbanc, B., Lazo, N. D., Buldyrev, S. V., Teplow, D. B., and Stanley, H. E. (2005) Folding events in the 21-30 region of amyloid β-protein (Aβ) studied in silico Proc. Natl. Acad. Sci. U.S.A. 102, 6015-6020 (Pubitemid 40594247)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.17
, pp. 6015-6020
-
-
Borreguero, J.M.1
Urbanc, B.2
Lazo, N.D.3
Buldyrev, S.V.4
Teplow, D.B.5
Stanley, H.E.6
-
21
-
-
69449099387
-
17-42 (p3) Oligomers: The Importance of the Turn Location and Its Conformation
-
17-42 (p3) Oligomers: The Importance of the Turn Location and Its Conformation Biophys. J. 97, 1168-1177
-
(2009)
Biophys. J.
, vol.97
, pp. 1168-1177
-
-
Miller, Y.1
Ma, B.2
Nussinov, R.3
-
22
-
-
28444442999
-
3D structure of Alzheimer's amyloid-β(1-42) fibrils
-
Lührs, T., Ritter, C., Adrian, M., Riek-Loher, D., Bohrmann, B., Döbeli, H., Schubert, D., and Riek, R. (2005) 3D structure of Alzheimer's amyloid-β(1-42) fibrils Proc. Natl. Acad. Sci. U.S.A. 102, 17342-17347
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 17342-17347
-
-
Lührs, T.1
Ritter, C.2
Adrian, M.3
Riek-Loher, D.4
Bohrmann, B.5
Döbeli, H.6
Schubert, D.7
Riek, R.8
-
23
-
-
0036438914
-
Solution structure of the Alzheimer amyloid β-peptide (1-42) in an apolar microenvironment: Similarity with a virus fusion domain
-
DOI 10.1046/j.1432-1033.2002.03271.x
-
Crescenzi, O., Tomaselli, S., Guerrini, R., Salvadori, S., D'Ursi, A. M., Temussi, P. A., and Picone, D. (2002) Solution structure of the Alzheimer amyloid β-peptide (1-42) in an apolar microenvironment Eur. J. Biochem. 269, 5642-5648 (Pubitemid 35365553)
-
(2002)
European Journal of Biochemistry
, vol.269
, Issue.22
, pp. 5642-5648
-
-
Crescenzi, O.1
Tomaselli, S.2
Guerrini, R.3
Salvadori, S.4
D'Ursi, A.M.5
Temussi, P.A.6
Picone, D.7
-
24
-
-
32344451179
-
The α-to-β conformational transition of Alzheimer's Aβ-(1-42) peptide in aqueous media is reversible: A step by step conformational analysis suggests the location of β conformation seeding
-
DOI 10.1002/cbic.200500223
-
Tomaselli, S., Esposito, V., Vangone, P., Nuland, N. A. J. v., Bonvin, A. M. J. J., Guerrini, R., Tancredi, T., Temussi, P. A., and Picone, D. (2006) The α-to-β Conformational Transition of Alzheimer's Aβ-(1-42) Peptide in Aqueous Media is Reversible: A Step by Step Conformational Analysis Suggests the Location of β Conformation Seeding ChemBioChem 7, 257-267 (Pubitemid 43220939)
-
(2006)
ChemBioChem
, vol.7
, Issue.2
, pp. 257-267
-
-
Tomaselli, S.1
Esposito, V.2
Vangone, P.3
Van Nuland, N.A.J.4
Bonvin, A.M.J.J.5
Guerrini, R.6
Tancredi, T.7
Temussi, P.A.8
Picone, D.9
-
25
-
-
22444449900
-
On the nucleation of amyloid β-protein monomer folding
-
DOI 10.1110/ps.041292205
-
Lazo, N. D., Grant, M. A., Condron, M. C., Rigby, A. C., and Teplow, D. B. (2005) On the nucleation of amyloid β -protein monomer folding Protein Sci. 14, 1581-1596 (Pubitemid 41007920)
-
(2005)
Protein Science
, vol.14
, Issue.6
, pp. 1581-1596
-
-
Lazo, N.D.1
Grant, M.A.2
Condron, M.C.3
Rigby, A.C.4
Teplow, D.B.5
-
26
-
-
42449111198
-
Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation
-
DOI 10.1073/pnas.0711731105
-
Hoyer, W., Grönwall, C., Jonsson, A., Ståhl, S., and Härd, T. (2008) Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation Proc. Natl. Acad. Sci. U.S.A. 105, 5099-5104 (Pubitemid 351738516)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.13
, pp. 5099-5104
-
-
Hoyer, W.1
Gronwall, C.2
Jonsson, A.3
Stahl, S.4
Hard, T.5
-
27
-
-
77957257176
-
Stabilization of neurotoxic Alzheimer amyloid-β oligomers by protein engineering
-
Sandberg, A., Luheshi, L. M., Söllvander, S., Barros, T. P. d, Macao, B., Knowles, T. P. J, Biverstål, H., Lendel, C., Ekholm-Petterson, F., Dubnovitsky, A., Lannfelt, L., Dobson, C. M., and Härd, T. (2010) Stabilization of neurotoxic Alzheimer amyloid-β oligomers by protein engineering Proc. Natl. Acad. Sci. U.S.A. 107, 15595-15600
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 15595-15600
-
-
Sandberg, A.1
Luheshi, L.M.2
Söllvander, S.3
Barros, T.P.D.4
MacAo, B.5
Knowles, T.P.J.6
Biverstål, H.7
Lendel, C.8
Ekholm-Petterson, F.9
Dubnovitsky, A.10
Lannfelt, L.11
Dobson, C.M.12
Härd, T.13
-
28
-
-
17644397372
-
Aβ40-lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid
-
DOI 10.1021/bi0474867
-
Sciaretta, K. L., Gordon, D. J., Petkova, A. T., Tycko, R., and Meredith, S. C. (2005) Aβ40-Lactam (D23/K28) Models a Conformation Highly Favorable for Nucleation of Amyloid Biochemistry 44, 6003-6014 (Pubitemid 40570694)
-
(2005)
Biochemistry
, vol.44
, Issue.16
, pp. 6003-6014
-
-
Sciarretta, K.L.1
Gordon, D.J.2
Petkova, A.T.3
Tycko, R.4
Meredith, S.C.5
-
29
-
-
79960476905
-
Azobenzene photoswitches for biomolecules
-
Beharry, A. A. and Woolley, G. A. (2011) Azobenzene photoswitches for biomolecules Chem. Soc. Rev 40, 4422-4437
-
(2011)
Chem. Soc. Rev
, vol.40
, pp. 4422-4437
-
-
Beharry, A.A.1
Woolley, G.A.2
-
30
-
-
22244487296
-
Photocontrolling Peptide α-Helices
-
Woolley, G. A. (2005) Photocontrolling Peptide α-Helices Acc. Chem. Res. 38, 486-493
-
(2005)
Acc. Chem. Res.
, vol.38
, pp. 486-493
-
-
Woolley, G.A.1
-
31
-
-
67849095782
-
Structure-Based Approach to the Photocontrol fo Protein Folding
-
Zhang, F., Zarrine-Afsar, A., Al-Abdul-Wahid, M. S., Prosser, R. S., Davidson, A. R., and Woolley, G. A. (2009) Structure-Based Approach to the Photocontrol fo Protein Folding J. Am. Chem. Soc. 131, 2283-2289
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 2283-2289
-
-
Zhang, F.1
Zarrine-Afsar, A.2
Al-Abdul-Wahid, M.S.3
Prosser, R.S.4
Davidson, A.R.5
Woolley, G.A.6
-
32
-
-
77952977698
-
Photocontrol of Coiled-Coil Proteins in Living Cells
-
Zhang, F., Timm, K. A., Arndt, K. M., and Woolley, G. A. (2010) Photocontrol of Coiled-Coil Proteins in Living Cells Angew. Chem., Int. Ed. 49, 3943-3946
-
(2010)
Angew. Chem., Int. Ed.
, vol.49
, pp. 3943-3946
-
-
Zhang, F.1
Timm, K.A.2
Arndt, K.M.3
Woolley, G.A.4
-
33
-
-
79952001500
-
Light-Triggered Aggregation and Disassembly of Amyloid-Like Structures
-
Deeg, A. A., Schrader, T. E., Kempter, S., Pfizer, J., Moroder, L., and Zinth, W. (2011) Light-Triggered Aggregation and Disassembly of Amyloid-Like Structures ChemPhysChem 12, 559-562
-
(2011)
ChemPhysChem
, vol.12
, pp. 559-562
-
-
Deeg, A.A.1
Schrader, T.E.2
Kempter, S.3
Pfizer, J.4
Moroder, L.5
Zinth, W.6
-
34
-
-
0033578647
-
Photomodulation of the conformation of cyclic peptides with azobenzene moieties in the peptide backbone
-
DOI 10.1002/(SICI)1521-3773(19990917)38:18<2771::AID-ANIE2771>3.0. CO;2-W
-
Behrendt, R., Renner, C., Schenk, M., Wang, F., Wachtveitl, J., Oesterhelt, D., and Moroder, L. (1999) Photomodulation of the Conformation of Cyclic Peptides with Azobenzene Moieties in the Peptide Backbone Angew. Chem., Int. Ed. 38, 2771-2774 (Pubitemid 29462851)
-
(1999)
Angewandte Chemie - International Edition
, vol.38
, Issue.18
, pp. 2771-2774
-
-
Behrendt, R.1
Renner, C.2
Schenk, M.3
Wang, F.4
Wachtveitl, J.5
Oesterhelt, D.6
Moroder, L.7
-
35
-
-
31344463473
-
A Photocontrolled β -Hairpin Peptide
-
Dong, S.-L., Loweneck, M., Schrader, T. E., Schreier, W. J., Moroder, L., and Renner, C. (2006) A Photocontrolled β -Hairpin Peptide Chem.π - πEur. J. 12, 1114-1120
-
(2006)
Chem.π - πEur. J.
, vol.12
, pp. 1114-1120
-
-
Dong, S.-L.1
Loweneck, M.2
Schrader, T.E.3
Schreier, W.J.4
Moroder, L.5
Renner, C.6
-
36
-
-
16844374069
-
Use of molecular dynamics in the design and structure determination of a photoinducible β-hairpin
-
DOI 10.1021/ja044253u
-
Kräutler, V., Aemissegger, A., Hünenberger, P. H., Hilvert, D., Hansson, T., and Gunsteren, W. F. v. (2005) Use of Molecular Dynamics in the Design and Structure Determination of a Photoinducible β-Hairpin J. Am. Chem. Soc. 127, 4935-4942 (Pubitemid 40489648)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.13
, pp. 4935-4942
-
-
Krautler, V.1
Aemissegger, A.2
Hunenberger, P.H.3
Hilvert, D.4
Hansson, T.5
Van Gunsteren, W.F.6
-
37
-
-
34347267670
-
Synthesis and application of an azobenzene amino acid as a light-switchable turn element in polypeptides
-
DOI 10.1038/nprot.2006.488, PII NPROT.2006.488
-
Aemissegger, A. and Hilvert, D. (2007) Synthesis and application of an azobenzene amino acid as a light-switchable turn element in polypeptides Nat. Protoc. 2, 161-167 (Pubitemid 47040079)
-
(2007)
Nature Protocols
, vol.2
, Issue.1
, pp. 161-167
-
-
Aemissegger, A.1
Hilvert, D.2
-
38
-
-
14844282762
-
A Photoinducible β-Hairpin
-
Aemissegger, A., Kräutler, V., Gunsteren, W. F. v., and Hilvert, D. (2005) A Photoinducible β-Hairpin J. Am. Chem. Soc. 127, 2929-2936
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 2929-2936
-
-
Aemissegger, A.1
Kräutler, V.2
Gunsteren, W.F.V.3
Hilvert, D.4
-
39
-
-
33749251222
-
Kinetics and Thermodynamics of Amyloid Assembly Using a High-Performance Liquid Chromatography-Based Sedimentation Assay
-
DOI 10.1016/S0076-6879(06)13003-7, PII S0076687906130037, Amyloid, Prions, and Other Protein Aggregates, Part C
-
O'Nuallain, B., Thakur, A. K., Williams, A. D., Bhattacharyya, A. M., Chen, S., Thiagarajan, G., and Wetzel, R. (2006) Kinetics and Thermodynamics of Amyloid Assembly Using a High-Performance Liquid Chromatography-Based Sedimentation Assay Methods Enzymol. 413, 34-74 (Pubitemid 44528684)
-
(2006)
Methods in Enzymology
, vol.413
, pp. 34-74
-
-
O'Nuallain, B.1
Thakur, A.K.2
Williams, A.D.3
Bhattacharyya, A.M.4
Chen, S.5
Thiagarajan, G.6
Wetzel, R.7
-
40
-
-
0035918550
-
Effect of environmental factors on the kinetics of insulin fibril formation: Elucidation of the molecular mechanism
-
DOI 10.1021/bi002555c
-
Nielsen, L., Khurana, R., Coats, A., Frokjaer, S., Brange, J., Vyas, S., Uversky, V. N., and Fink, A. L. (2001) Effect of Environmental Factors on the Kinetics of Insulin Fibril Formation: Elucidation of the Molecular Mechanism Biochemistry 40, 6036-6046 (Pubitemid 32466306)
-
(2001)
Biochemistry
, vol.40
, Issue.20
, pp. 6036-6046
-
-
Nielsen, L.1
Khurana, R.2
Coats, A.3
Frokjaer, S.4
Brange, J.5
Vyas, S.6
Uversky, V.N.7
Fink, A.L.8
-
41
-
-
3343003514
-
Techniques to study amyloid fibril formation in vitro
-
DOI 10.1016/j.ymeth.2004.03.012, PII S104620230400060X
-
Nilsson, M. R. (2004) Techniques to study amyloid fibril formation in vitro Methods 34, 151-160 (Pubitemid 38993215)
-
(2004)
Methods
, vol.34
, Issue.1
, pp. 151-160
-
-
Nilsson, M.R.1
-
42
-
-
33744981623
-
Image Processing with ImageJ
-
Abramoff, M. D., Magelhaes, P. J., and Ram, S. J. (2004) Image Processing with ImageJ Biophotonics Int. 11, 36-42
-
(2004)
Biophotonics Int.
, vol.11
, pp. 36-42
-
-
Abramoff, M.D.1
Magelhaes, P.J.2
Ram, S.J.3
-
43
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
-
DOI 10.1074/jbc.M201750200
-
Dahlgren, K. N., Manelli, A. M., Stine, W. B., Baker, L. K., Krafft, G. A., and LaDu, M. J. (2002) Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability J. Biol. Chem. 277, 32046-32053 (Pubitemid 34969015)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.35
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Blaine Stine Jr., W.3
Baker, L.K.4
Krafft, G.A.5
Ladu, M.J.6
-
44
-
-
0038176528
-
In vitro characterization of conditions for amyloid-β peptide oligomerization and fibrillogenesis
-
DOI 10.1074/jbc.M210207200
-
Stine, W. B., Dahlgren, K. N., Krafft, G. A., and LaDu, M. J. (2003) In vitro characterization of conditions for amyloid-β peptide oligomerization and fibrillogenesis J. Biol. Chem. 278, 11612-11622 (Pubitemid 36792723)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11612-11622
-
-
Stine Jr., W.B.1
Dahlgren, K.N.2
Krafft, G.A.3
LaDu, M.J.4
-
45
-
-
36749033116
-
Peptide conformation and supramolecular organization in amylin fibrils: Constraints from solid-state NMR
-
DOI 10.1021/bi701427q
-
Luca, S., Yau, W.-M., Leapman, R., and Tycko, R. (2007) Peptide Conformation and Supramolecular Organization in Amylin Fibrils: Constraints from Solid-State NMR Biochemistry 46, 13505-13522 (Pubitemid 350209947)
-
(2007)
Biochemistry
, vol.46
, Issue.47
, pp. 13505-13522
-
-
Luca, S.1
Yau, W.-M.2
Leapman, R.3
Tycko, R.4
-
46
-
-
0032849874
-
Quantification of β-Sheet Amyloid Fibril Structures with Thioflavin T
-
LeVine, H. (1999) Quantification of β-Sheet Amyloid Fibril Structures with Thioflavin T Methods Enzymol. 309, 274-284
-
(1999)
Methods Enzymol.
, vol.309
, pp. 274-284
-
-
Levine, H.1
-
47
-
-
0032877134
-
Analysis of protein aggregation kinetics
-
DOI 10.1016/S0076-6879(99)09019-9
-
Ferrone, F. (1999) Analysis of Protein Aggregation Kinetics Methods Enzymol. 309, 256-274 (Pubitemid 29446454)
-
(1999)
Methods in Enzymology
, vol.309
, pp. 256-274
-
-
Ferrone, F.1
-
48
-
-
0027492164
-
Determination of protein secondary structure by Fourier transform infrared spectroscopy: A critical assessment
-
DOI 10.1021/bi00053a001
-
Surewicz, W. K., Mantsch, H. H., and Chapman, D. (1993) Determination of Protein Secondary Structure by Fourier Transform Infrared Spectroscopy: A Critical Assessment Biochemistry 32, 389-394 (Pubitemid 23034873)
-
(1993)
Biochemistry
, vol.32
, Issue.2
, pp. 389-394
-
-
Surewicz, W.K.1
Mantsch, H.H.2
Chapman, D.3
-
49
-
-
0033584815
-
An FT-IR Study of the β -Amyloid Conformation: Standardization of Aggregation Grade
-
Szabó, Z., Klement, é., Jost, K., Zarándi, M., Soós, K., and Penke, B. (1999) An FT-IR Study of the β -Amyloid Conformation: Standardization of Aggregation Grade Biochem. Biophys. Res. Commun. 265, 297-300
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.265
, pp. 297-300
-
-
Szabó, Z.1
Klement, E.2
Jost, K.3
Zarándi, M.4
Soós, K.5
Penke, B.6
-
50
-
-
0035865539
-
Temperature-induced conformational changes in amyloid β(1-40) peptide investigated by simultaneous FT-IR microspectroscopy with thermal system
-
DOI 10.1016/S0301-4622(00)00228-3, PII S0301462200002283
-
Chu, H.-L. and Lin, C.-Y. (2001) Temperature-induced conformational changes in amyloid β (1-40) peptide investigated by simultaneous FT-IR microspectroscopy with thermal system Biophys. Chem. 89, 173-180 (Pubitemid 32143807)
-
(2001)
Biophysical Chemistry
, vol.89
, Issue.2-3
, pp. 173-180
-
-
Chu, H.-L.1
Lin, S.-Y.2
-
51
-
-
0033579545
-
Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin
-
DOI 10.1006/jmbi.1999.3286
-
Nilsson, M. R. and Raleigh, D. P. (1999) Analysis of Amylin Cleavage Products Provides New Insights into the Amyloidogenic Region of Human Amylin J. Mol. Biol. 294, 1375-1385 (Pubitemid 30008807)
-
(1999)
Journal of Molecular Biology
, vol.294
, Issue.5
, pp. 1375-1385
-
-
Nilsson, M.R.1
Raleigh, D.P.2
-
52
-
-
0024363054
-
Two simple methods for quantifying low-affinity dye-substrate binding
-
Klunk, W. E., Pettegrew, J. W., and Abraham, D. J. (1989) Two Simple Methods for Quantifying Low-affinity Dye-Substrate Binding J. Histochem. Cytochem. 37, 1293-1297 (Pubitemid 19186032)
-
(1989)
Journal of Histochemistry and Cytochemistry
, vol.37
, Issue.8
, pp. 1293-1297
-
-
Klunk, W.E.1
Pettegrew, J.W.2
Abraham, D.J.3
-
53
-
-
14944378094
-
Certain inhibitors of synthetic amyloid β-peptide (Aβ) fibrillogenesis block oligomerization of natural Aβ and thereby rescue long-term potentiation
-
DOI 10.1523/JNEUROSCI.4391-04.2005
-
Walsh, D. M., Townsend, M., Podlisny, M. B., Shankar, G. M., Fadeeva, J. V., Agnaf, O. E., Harley, D. M., and Selkoe, D. J. (2005) Certain Inhibitors of Synthetic Amyloid β-Peptide (Aβ) Fibrillogenesis Block Oligomerization of Natural Aβ and Thereby Rescue Long-Term Potentiation J. Neurosci. 25, 2455-2462 (Pubitemid 40365155)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.10
, pp. 2455-2462
-
-
Walsh, D.M.1
Townsend, M.2
Podlisny, M.B.3
Shankar, G.M.4
Fadeeva, J.V.5
El Agnaf, O.6
Hartley, D.M.7
Selkoe, D.J.8
-
54
-
-
25444522601
-
Thermodynamics of Aβ(1-40) amyloid fibril elongation
-
DOI 10.1021/bi050927h
-
O'Nuallain, B., Shivaprasad, S., Kheterpal, I., and Wetzel, R. (2005) Thermodynamics of Aβ(1-40) Amyloid Fibril Formation Biochemistry 44, 12709-12718 (Pubitemid 41377310)
-
(2005)
Biochemistry
, vol.44
, Issue.38
, pp. 12709-12718
-
-
O'Nuallain, B.1
Shivaprasad, S.2
Kheterpal, I.3
Wetzel, R.4
-
55
-
-
17644397372
-
Aβ40-lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid
-
DOI 10.1021/bi0474867
-
Sciarretta, K. L., Gordon, D. J., Petkova, A. T., Tycko, R., and Meredith, S. C. (2005) Aβ40-Lactam (D23/K28) Models a Conformation Highly Favorable for Nucleation of Amyloid Biochemistry 44, 6003-6014 (Pubitemid 40570694)
-
(2005)
Biochemistry
, vol.44
, Issue.16
, pp. 6003-6014
-
-
Sciarretta, K.L.1
Gordon, D.J.2
Petkova, A.T.3
Tycko, R.4
Meredith, S.C.5
-
56
-
-
58149333149
-
A New Amyloid-Like β-Aggregate with Amyloid Characteristics, Except Fibril Morphology
-
Chang, E. S.-H., Liao, T.-Y., Lim, T.-S., Fann, W., and Chen, R. P.-Y. (2009) A New Amyloid-Like β-Aggregate with Amyloid Characteristics, Except Fibril Morphology J. Mol. Biol. 385, 1257-1265
-
(2009)
J. Mol. Biol.
, vol.385
, pp. 1257-1265
-
-
Chang, E.S.-H.1
Liao, T.-Y.2
Lim, T.-S.3
Fann, W.4
Chen, R.P.-Y.5
-
57
-
-
0030992473
-
Insights on β-hairpin stability in aqueous solution from peptides with enforced type I' and type II β-turns
-
DOI 10.1021/ja963653h, PII S0002786396036530
-
Haque, T. S. and Gellman, S. H. (1997) Insights on β-Hairpin Stability in Aqueous Solution from Peptides with Enforced Type I- and Type II- β-Turns J. Am. Chem. Soc. 119, 2303-2304 (Pubitemid 27160004)
-
(1997)
Journal of the American Chemical Society
, vol.119
, Issue.9
, pp. 2303-2304
-
-
Haque, T.S.1
Gellman, S.H.2
|